EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

gamma-cyclodextrin

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CAS Number: 17465-86-0Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:241-482-4
FDA UNII:KZJ0BYZ5VA
Beilstein Number:078740
MDL:MFCD00009595
XlogP3-AA:-17.20 (est)
Molecular Weight:1297.13360000
Formula:C48 H80 O40
NMR Predictor:Predict (works with chrome or firefox)
Category:carrier solvents, flavor modifiers, stabilizers
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
GRN 46 Gamma cyclodextrin View - notice PDF
JECFA Food Additive: gamma-Cyclodextrin
GSFA Codex: Cyclodextrin, gamma- (458)
 
Physical Properties:
Appearance:white crystalline solid (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 alcohol, slightly
 
Organoleptic Properties:
Odor Description:at 100.00 %. odorless
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Sugammadex Impurity 1 (Cyclooctapentylose)
Glentham Life Sciences
gamma-Cyclodextrin
Santa Cruz Biotechnology
For experimental / research use only.
gamma-Cyclodextrin
Sigma-Aldrich: Sigma
For experimental / research use only.
gamma-Cyclodextrin ≥98%
TCI AMERICA
For experimental / research use only.
gamma-Cyclodextrin >99.0%(HPLC)
Chemical Sources Association
Need This Item for Flavor/Food?: You can contact the Chemical Sources Association
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
carrier solvents, flavor modifiers, stabilizers
Recommendation for gamma-cyclodextrin usage levels up to:
 not for fragrance use.
 
Recommendation for gamma-cyclodextrin flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):17465-86-0
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :86575
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:2
Chemidplus:0017465860
RTECS:GU2293080 for cas# 17465-86-0
 
References:
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):86575
Pubchem (sid):135044763
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):HMDB29927
FooDB:FDB001186
Export Tariff Code:3505.10.0020
FDA Listing of Food Additive Status:View
ChemSpider:View
Wikipedia:View
FAO:CYCLODEXTRIN
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
.gama.-cyclodextrin
 cyclooctapentylose
 dexy pearl gamma-100
 ringdex C
 

Articles:

PubMed:Sensory properties of ginseng solutions modified by masking agents.
PubMed:Rational development of taste masked oral liquids guided by an electronic tongue.
PubMed:The effect of solvent interactions on alpha-, beta-, and gamma-cyclodextrin/flavor molecular inclusion complexes.
PubMed:Encapsulation of shiitake (Lenthinus edodes) flavors by spray drying.
PubMed:Cyclodextrin encapsulation to prevent the loss of l-menthol and its retention during drying.
PubMed:GC Separation of Enantiomers of Alkyl Esters of 2-Bromo Substituted Carboxylic Acids Enantiomers on 6-TBDMS-2,3-di-alkyl- β- and γ-Cyclodextrin Stationary Phases.
PubMed:Influence of oral supplementation with sesamin on longevity of Caenorhabditis elegans and the host defense.
PubMed:R-α lipoic acid γ-cyclodextrin complex increases energy expenditure: a 4-month feeding study in mice.
PubMed:Hydroxypropyl-β-cyclodextrin impacts renal and systemic hemodynamics in the anesthetized dog.
PubMed:Enhanced production of γ-cyclodextrin by optimization of reaction of γ-cyclodextrin glycosyltransferase as well as synchronous use of isoamylase.
PubMed:Oral administration of monogalactosyl diacylglycerol from spinach inhibits colon tumor growth in mice.
PubMed:Aqueous solubility and stability enhancement of astilbin through complexation with cyclodextrins.
PubMed:Structure selective complexation of cyclodextrins with five polyphenols investigated by capillary electrokinetic chromatography.
PubMed:Empirical, thermodynamic and quantum-chemical investigations of inclusion complexation between flavanones and (2-hydroxypropyl)-cyclodextrins.
PubMed:An investigation into the supramolecular structure, solubility, stability and antioxidant activity of rutin/cyclodextrin inclusion complex.
PubMed:Gamma-cyclodextrin production using cyclodextrin glycosyltransferase from Bacillus clarkii 7364.
PubMed:Development of a method for oral administration of hydrophobic substances to Caenorhabditis elegans: pro-longevity effects of oral supplementation with lipid-soluble antioxidants.
PubMed:Comparative effect of the addition of α-, β-, or γ-cyclodextrin on main sensory and physico-chemical parameters.
PubMed:Distribution and organoleptic impact of ethyl 2-hydroxy-4-methylpentanoate enantiomers in wine.
PubMed:Nanoporous carbohydrate metal-organic frameworks.
PubMed:Sensory properties of ginseng solutions modified by masking agents.
PubMed:Determination of sugammadex in human plasma, urine, and dialysate using a high-performance liquid chromatography/tandem mass spectrometry assay.
PubMed:Transglycosylation properties of maltodextrin glucosidase (MalZ) from Escherichia coli and its application for synthesis of a nigerose-containing oligosaccharide.
PubMed:Chiral separation of (+)/(-)-catechin from sulfated and glucuronidated metabolites in human plasma after cocoa consumption.
PubMed:Composition of aldrin, dieldrin, and photodieldrin enantiomers in technical and environmental samples.
PubMed:Update on neuromuscular pharmacology.
PubMed:Cyclodextrin inclusion complex formation and solid-state characterization of the natural antioxidants alpha-tocopherol and quercetin.
PubMed:(-)-Catechin in cocoa and chocolate: occurrence and analysis of an atypical flavan-3-ol enantiomer.
PubMed:gamma-Cyclodextrin: a review on enzymatic production and applications.
PubMed:Enantioseparation of isoxanthohumol in beer by hydroxypropyl-gamma-cyclodextrin-modified micellar electrokinetic chromatography.
PubMed:Biochemical and structural features of a novel cyclodextrinase from cow rumen metagenome.
PubMed:GC separation of 2-substituted ethyl propionate enantiomers on permethylated and 2,6-dimethyl-3-pentyl beta- and gamma-cyclodextrin stationary phases.
PubMed:Pullulans and gamma-cyclodextrin affect apparent digestibility and metabolism in healthy adult ileal cannulated dogs.
PubMed:2-Hydroxypropyl-beta-cyclodextrin (HP-beta-CD): a toxicology review.
PubMed:Separation of enantiomers of butorphanol and cycloamine by capillary zone electrophoresis.
PubMed:On the capillary gas chromatographic separation of enantiomers of N-trifluoroacetyl-O-alkyl esters of selected amino acids on 2,3-di-O-pentyl-6-O-acyl cyclodextrins.
PubMed:The effect of solvent interactions on alpha-, beta-, and gamma-cyclodextrin/flavor molecular inclusion complexes.
PubMed:Encapsulation of shiitake (Lenthinus edodes) flavors by spray drying.
PubMed:Stability of natamycin and its cyclodextrin inclusion complexes in aqueous solution.
PubMed:Formation of natamycin:cyclodextrin inclusion complexes and their characterization.
PubMed:Determination of monoterpene hydrocarbons and alcohols in Majorana hortensis Moench by micellar electrokinetic capillary chromatographic.
PubMed:Inclusion complex of conjugated linoleic acid (CLA) with cyclodextrins.
PubMed:Enantioseparation of vinclozolin by gamma-cyclodextrin-modified micellar electrokinetic chromatography.
PubMed:Enantioseparation of chiral thiobarbiturates using cyclodextrin-modified capillary electrophoresis.
PubMed:Evaluation of certain food additives and contaminants.
PubMed:Starch digestion in tropical fishes: isolation, structural studies and inhibition kinetics of alpha-amylases from two tilapias Oreochromis niloticus and Sarotherodon melanotheron.
PubMed:Evaluation of certain food additives. Fifty-first report of the Joint FAO/WHO Expert Committee on Food Additives.
PubMed:Gastrointestinal tolerance of gamma-cyclodextrin in humans.
PubMed:Structure elucidation, enantioselective analysis, and biogenesis of nerol oxide in Pelargonium species.
PubMed:Biogenetic studies in Mentha x piperita. 1. deuterium-labeled monoterpene ketones: synthesis and stereoselective analysis.
PubMed:Analysis of food oligosaccharides using MALDI-MS: quantification of fructooligosaccharides.
PubMed:Subchronic intravenous toxicity studies with gamma-cyclodextrin in rats.
PubMed:Subchronic oral toxicity studies with gamma-cyclodextrin in rats.
PubMed:Embryotoxicity and teratogenicity study with gamma-cyclodextrin in rabbits.
PubMed:Embryotoxicity and teratogenicity study with gamma-cyclodextrin in rats.
PubMed:Subchronic (13-week) oral toxicity study of gamma-cyclodextrin in dogs.
PubMed:Disposition of [14C]gamma-cyclodextrin in germ-free and conventional rats.
PubMed:Chiral gas chromatographic determination of ephedrine-type alkaloids in dietary supplements containing Má Huáng.
PubMed:Postcolumn excitation of aflatoxins using cyclodextrins in liquid chromatography for food analysis.
PubMed:Inhibition of dextran and mutan synthesis by cycloisomaltooligosaccharides.
PubMed:Safety of oral cyclodextrins: effects of hydroxypropyl cyclodextrins, cyclodextrin sulfates and cationic cyclodextrins on steroid balance in rats.
PubMed:Evidence for beta-galactosidase catalyzed hydrolysis of paranitrophenyl-beta-D-galactopyranoside anchored in cyclodextrins.
 
Notes:
Stabiliser, emulsifier, carrier and formulation aid. Generally recognised as safe (GRAS) in the USA
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