| Category:food-contact surface of paper and paperboard   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:   Physical Properties: 
| Food Chemicals Codex Listed: | No |  | Specific Gravity: | 1.08300 @  25.00 °C. |  | Boiling Point: | -19.50 °C. @  760.00 mm Hg (est) |  | Vapor Pressure: | 3463.820068 mmHg @  25.00 °C. (est) |  | Flash Point: | 133.00 °F. TCC (   56.11 °C. ) |  | logP (o/w): | 0.350 |  | Soluble in: |  |  | water, 400000 mg/L @ 20 °C (exp) |    Organoleptic Properties: 
| Odor and/or flavor descriptions from others (if found). |    Cosmetic Information:   Suppliers:   Safety Information: 
| Preferred SDS: View |  |  |  | Hazards identification |  |  |  | Classification of the substance or mixture |  | GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |  | None found. |  | GHS Label elements, including precautionary statements |  |  |  | Pictogram |  |  |  |  | Hazard statement(s) |  | None found. |  | Precautionary statement(s) |  | None found. |  | Oral/Parenteral Toxicity: |  | intravenous-cat LDLo  30 mg/kg BLOOD: OTHER CHANGES
 Acta Pharmacologica et Toxicologica. Vol. 8, Pg. 275, 1952.
 
 intravenous-dog LDLo  70 mg/kg
 International Polymer Science and Technology. Vol. 3, Pg. 93, 1976.
 
 parenteral-frog LDLo  800 ug/kg
 International Polymer Science and Technology. Vol. 3, Pg. 93, 1976.
 
 oral-guinea pig LD50  260 mg/kg
 Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.
 
 unreported-man LDLo  477 mg/kg
 "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
 
 oral-man TDLo  643 mg/kg
 GASTROINTESTINAL: NAUSEA OR VOMITING
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY OBSTRUCTION
GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH
 Japanese Journal of Toxicology. Vol. 4, Pg. 261, 1991.
 
 oral-man TDLo  646 mg/kg
 GASTROINTESTINAL: NAUSEA OR VOMITING
GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH
GASTROINTESTINAL: GASTRITIS
 Japanese Journal of Toxicology. Vol. 4, Pg. 261, 1991.
 
 oral-mouse LD50  42 mg/kg
 BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: EXCITEMENT
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
 National Technical Information Service. Vol. AD-A125-539
 
 intraperitoneal-mouse LDLo  16 mg/kg
 Toxicology and Applied Pharmacology. Vol. 23, Pg. 288, 1972.
 
 intravenous-rabbit LDLo  48 mg/kg
 Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 213, 1955.
 
 intravenous-rat LD50  87 mg/kg
 Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 221, Pg. 166, 1954.
 
 oral-rat LD50  100 mg/kg
 Food and Chemical Toxicology. Vol. 26, Pg. 447, 1988.
 
 
 |  | Dermal Toxicity: |  | subcutaneous-dog LDLo 350 mg/kg International Polymer Science and Technology. Vol. 3, Pg. 93, 1976.
 
 subcutaneous-mouse LD50 300 mg/kg
 LUNGS, THORAX, OR RESPIRATION: BRONCHIOLAR CONSTRICTION
LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA
 Acta Pharmacologica et Toxicologica. Vol. 6, Pg. 299, 1950.
 
 skin-rabbit LD50 270 uL/kg
 Union Carbide Data Sheet. Vol. 4/21/1967
 
 subcutaneous-rabbit LDLo 240 mg/kg
 JAMA, Journal of the American Medical Association. Vol. 62, Pg. 984, 1914.
 
 subcutaneous-rat LD50 420 mg/kg
 LUNGS, THORAX, OR RESPIRATION: BRONCHIOLAR CONSTRICTION
LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA
 Acta Pharmacologica et Toxicologica. Vol. 6, Pg. 299, 1950.
 
 
 |  | Inhalation Toxicity: |  | inhalation-cat LCLo 400 mg/m3/2H "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 69, 1982.
 
 inhalation-human TCLo 17 mg/m3/30M
 SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
 JAMA, Journal of the American Medical Association. Vol. 165, Pg. 1908, 1957.
 
 inhalation-man TCLo 300 ug/m3
 BEHAVIORAL: AGGRESSION
SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION
 Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 12(7), Pg. 20, 1968.
 
 inhalation-mouse LC50 454000 mg/m3/4H
 Current Toxicology. Vol. 1, Pg. 47, 1993.
 
 inhalation-rat LC50 203 mg/m3
 BEHAVIORAL: EXCITEMENT
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE
 Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 18(2), Pg. 55, 1974.
 
 
 |    Safety in Use Information: 
| Category: |  | food-contact surface of paper and paperboard |  | Recommendation for formaldehyde usage levels up to: |  |  | not for fragrance use. |  |  |  | Recommendation for formaldehyde flavor usage levels up to: |  |  | not for flavor use. |  | NOEL (No Observed Effect Level): | 15 (mg/kg bw per day) |    Safety References: 
| European Food Safety Authority (EFSA) reference(s): 
 
 |  | Flavouring Group Evaluation 8 (FGE.08)[1]: Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical group 20 View page or View pdf
 
 
 |  | Scientific Opinion on Flavouring Group Evaluation 20, Revision 3(FGE.20Rev3): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf
 
 
 |  | Report of ESCO WG on non-plastic Food Contact Materials View page or View pdf
 
 
 |  | Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to use of formaldehyde as a preservative during the manufacture and preparation of food additives View page or View pdf
 
 
 |  | Reasoned opinion on the modification of the existing MRLs for metaldehyde in certain legume vegetables and pulses View page or View pdf
 
 
 |  | Scientific Opinion on the re-evaluation of hexamethylene tetramine (E 239) as a food additive View page or View pdf
 
 
 |  | Scientific Opinion on the safety and efficacy of formaldehyde as a feed hygiene substance in feed for pigs and poultry View page or View pdf
 
 
 |  | EFSA scientific advice to EC on accumulating formaldehyde in GM soybeans View page or View pdf
 
 
 |  | EPI System: View |  | EPA-Iris:IRIS |  | ClinicalTrials.gov:search |  | Daily Med:search |  | NIOSH International Chemical Safety Cards:search |  | NIOSH Pocket Guide:search |  | Chemical Carcinogenesis Research Information System:Search |  | AIDS Citations:Search |  | Cancer Citations:Search |  | Toxicology Citations:Search |  | Carcinogenic Potency Database:Search |  | EPA GENetic TOXicology:Search |  | EPA Substance Registry Services (TSCA):50-00-0 |  | EPA ACToR:Toxicology Data |  | EPA Substance Registry Services (SRS):Registry |  | Laboratory Chemical Safety Summary :712 |  | National Institute of Allergy and Infectious Diseases:Data |  | WGK Germany:2 |  | formaldehyde |  | Chemidplus:0000050000 |  | EPA/NOAA CAMEO:hazardous materials |  | RTECS:50-00-0 |    References:   Other Information: 
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |  | Videos: | The Periodic Table of Videos |  | tgsc: | Atomic Weights use for this web site |  | (IUPAC): | Periodic Table of the Elements |  | FDA Substances Added to Food (formerly EAFUS): | View |  | FDA Indirect Additives used in Food Contact Substances: | View |  | CHEBI: | View |  | CHEMBL: | View |  | Metabolomics Database: | Search |  | UM BBD: | Search |  | KEGG (GenomeNet): | C00067 |  | HMDB (The Human Metabolome Database): | HMDB01426 |  | FooDB: | FDB009445 |  | YMDB (Yeast Metabolome Database): | YMDB00321 |  | Export Tariff Code: | 2912.11.0000 |  | FDA Listing of Food Additive Status: | View |  | VCF-Online: | VCF Volatile Compounds in Food |  | ChemSpider: | View |  | Wikipedia: | View |  | Formulations/Preparations: •pure formaldehyde is not avail commercially because of its tendency to polymerize. it is sold as aqueous solutions containing from 37% to 50% formaldehyde by wt & varying amounts of methanol.
•marketed under the trade name formcel, soln in methanol, n-butanol, and isobutanol. ...
•aq formaldehyde, known as formalin, is usually 37% by weight of formaldehyde, though more concn soln are available. formalin is the general-purpose formaldehyde of commerce supplied unstabilized or methanol-stabilized. formaldehyde may also exist in the form of the cyclic trimer trioxane. this is a fairly stable cmpd that does not easily release formaldehyde. ...
•grade: aqueous solutions: 37%, 44%, 50% inhibited (with varying percentages of methanol) or stabilized or unstabilized (methanol-free), also available in solution in n-butanol, ethanol, or urea; usp (37% aqueous solution containing methanol).
•soluble concentrate; hot fogging concentrate
•formaldehyde is available in the united states as as paraformaldehyde. paraformaldehyde is available as a powdered or flaked product that contains the equivalent of 90-93% formaldehyde, a maximum of 9% water, and a maximum of 0.03% acidity as formic acid. it is readily soluble in hot water with the evolution of formaldehyde vapors ...
•formalin consists of an aqueous solution of formaldehyde, usually containing about 37% formaldehyde and 12-15% methanol. formalin
 |    Potential Blenders and core components note  Potential Uses:   Occurrence (nature, food, other):note  Synonyms: 
|  | formalin |  |  | formic aldehyde |  |  | formol |  |  | methaldehyde |  |  | methanal |  |  | methyl aldehyde |  |  | paraform |    Articles:  | 
| a highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. in solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant, and as a laboratory fixative or preservative. formaldehyde solution (formalin) is considered a hazardous compound, and its vapor toxic. (from reynolds, martindale the extra pharmacopoeia, 30th ed, p717) A highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons.
 |