ci 45350:1
3,6-dihydroxyspiro[xanthene-9,3'-phthalide]

Supplier Sponsors

• 
  Glentham Life Sciences Ltd

  The Chemical, Biochemical & Research Essentials Supplier
  Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK.
  With a Glentham Life Sciences account you can view more product details, request quotes and order products online.
  Email:	Info
  Email:	Sales
  Email:	Tech Support
  Voice: +44 (0) 1225 667798
  Fax: +44 (0) 2033 978909
  Facebook
  Twitter
  Linkedin
  Google+
  News
  Distribution
  Products List:	View
  CODE124716 CODE124716
  Product(s):
  GT3509 Fluorescein (C.I. 45350)

Name: 3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one CAS Number: 2321-07-5 3D/inchi Other(deleted CASRN): 126605-73-0 ECHA EINECS - REACH Pre-Reg: 219-031-8 FDA UNII: TPY09G7XIR Nikkaji Web: J7.875A Beilstein Number: 0094324 MDL: MFCD00005050 XlogP3-AA: 3.40 (est) Molecular Weight: 332.31164000 Formula: C20 H12 O5 BioActivity Summary: listing NMR Predictor: Predict (works with chrome, Edge or firefox) Category:hair dyeing agents   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search   Physical Properties: Appearance: yellow to orange amorphous solid (est) Assay: 95.00 to 100.00 Food Chemicals Codex Listed: No Melting Point: 315.00 °C. @ 760.00 mm Hg Boiling Point: 620.80 °C. @ 760.00 mm Hg (est) Flash Point: 451.00 °F. TCC ( 232.60 °C. ) (est) logP (o/w): 2.980 (est) Soluble in:   water, 3.212 mg/L @ 25 °C (est)   Organoleptic Properties: Odor and/or flavor descriptions from others (if found).   Cosmetic Information: CosIng: cosmetic data Cosmetic Uses: hair dyeing agents   Suppliers: Abbey Color Fluorescein, Fluorescein Dye, Fluorescein USP Odor: characteristic Use: Abbey Color’s customers for fluorescein are companies that manufacture the application dosages in which fluorescein is a component. Glentham Life Sciences Fluorescein (C.I. 45350) Santa Cruz Biotechnology For experimental / research use only. Fluorescein (free acid) Dye content 95% Sigma-Aldrich: Aldrich For experimental / research use only. Fluorescein (free acid) sds Dye content 95 %   Safety Information: Preferred SDS: View   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) None found. GHS Label elements, including precautionary statements   Pictogram   Hazard statement(s) None found. Precautionary statement(s) None found. Oral/Parenteral Toxicity: unreported-guinea pig LDLo 400 mg/kg "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935. intravenous-man TDLo 7143 nL/kg SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" GASTROINTESTINAL: NAUSEA OR VOMITING American Journal of Ophthalmology. Vol. 126, Pg. 837, 1998. intravenous-mouse LD50 300 mg/kg United States Patent Document. Vol. #4775625 unreported-mouse LDLo 600 mg/kg "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935. intravenous-rabbit LDLo 300 mg/kg International Journal of Leprosy and Other Mycobacterial Diseases. Vol. 2, Pg. 257, 1934. intraperitoneal-rat LDLo 600 mg/kg International Journal of Leprosy and Other Mycobacterial Diseases. Vol. 2, Pg. 257, 1934. Dermal Toxicity: Not determined Inhalation Toxicity: Not determined   Safety in Use Information: Category: hair dyeing agents Recommendation for ci 45350:1 usage levels up to:   not for fragrance use.   Recommendation for ci 45350:1 flavor usage levels up to:   not for flavor use.   Safety References: EPI System: View ClinicalTrials.gov:search Daily Med:search Chemical Carcinogenesis Research Information System:Search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA GENetic TOXicology:Search EPA Substance Registry Services (TSCA):2321-07-5 EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :16850 National Institute of Allergy and Infectious Diseases:Data WGK Germany:3 3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one Chemidplus:0002321075 EPA/NOAA CAMEO:hazardous materials RTECS:LM5075000 for cas# 2321-07-5   References:   3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one NIST Chemistry WebBook: Search Inchi Canada Domestic Sub. List: 2321-07-5 Pubchem (cid): 16850 Pubchem (sid): 135050608   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements CHEBI: View CHEMBL: View Golm Metabolome Database: Search KEGG (GenomeNet): D01261 HMDB (The Human Metabolome Database): HMDB14831 Export Tariff Code: 2932.90.4500 FDA Color Additive Status List View ChemSpider: View Wikipedia: View EFSA Update of results on the monitoring of furan levels in food: Read Report EFSA Previous report: Results on the monitoring of furan levels in food: Read Report EFSA Report of the CONTAM Panel on provisional findings on furan in food: Read Report Formulations/Preparations: •fluorescite (fluorescein injection, usp) 10% contains fluorescein sodium (equivalent to fluorescein 10% wv. •ak-fluor (fluorescein injection, usp) 10% is 100 mgml in a 5 ml single vial and ak-fluor (fluorescein injection, usp) 25% is 250 mgml in a 2 ml single dose vial   Potential Blenders and core components note None Found   Potential Uses:   cosmetic colorants   Occurrence (nature, food, other):note   not found in nature   Synonyms:   benzoic acid, 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-   benzoic acid, o-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-   c.i. 45350:1   C.I. 45350.1   C.I. acid yellow 73   C.I. solvent yellow 94 9-(o- carboxyphenyl)-6-hydroxy-3-isoxanthenone 9-(o- carboxyphenyl)-6-hydroxy-3h-xanthen-3-one   D & C yellow no. 7   D & C yellow no. 8   D and C yellow no. 7   D&C yellow no. 7   dc yellow no. 7 3',6'- dihydroxy-3H-spiro[2-benzofuran-1,9'-xanthen]-3-one 3',6'- dihydroxy-3H-spiro[isobenzofuran-1,9'-xanthen]-3-one 3',6'- dihydroxyfluoran 3',6'- dihydroxyspiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one 3',6'- dihydroxyspiro(isobenzofuran-1(3H),9'(9H)-xanthen)-3-one 3,6- dihydroxyspiro(xanthene-9,3'-phthalide) 3',6'- dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one 12,15- dihydroxyspiro[3-hydroisobenzofuran-3,9'-xanthene]-1-one 3',6'- dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one 3,6- dihydroxyspiro[xanthene-9,3'-phthalide]   fluoran, 3',6'-dihydroxy- 3,6- fluorandiol 3',6'- fluorandiol   fluorescein   fluoresceine   fluorescite   ful-glo   funduscein 2-(6- hydroxy-3-oxo-(3H)-xanthen-9-yl) benzoic acid 2-(6- hydroxy-3-oxo-(3H)-xanthen-9-yl)benzoic acid 2-(6- hydroxy-3-oxo-3H-xanthen-9-yl)-benzoic acid 2-(3- hydroxy-6-oxo-6H-xanthen-9-yl)benzoic acid   japan yellow 201   japan yellow no. 201   soap yellow F   solvent yellow 94   spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 3',6'-dihydroxy- 3H- xanthen-3-one, 9-(o-carboxyphenyl)-6-hydroxy-   Articles:   None found yet. Try the PubMed Search.

Notes: a phthalic indicator dye that appears yellow-green in normal tear film and bright green in a more alkaline medium, such as the aqueous humor, and is used therapeutically as a diagnostic aid in corneal injuries and corneal trauma. it has been approved by fda for use in externally applied drugs and cosmetics. (from merck index, 12th ed; american medical association drug evaluations; 1995, p2275)