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Category:indirect food additives: adhesives and components of coatings
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.03000 @ 25.00 °C.
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| Refractive Index: | 1.52100 @ 20.00 °C.
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| Melting Point: | -9.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 225.00 to 226.00 °C. @ 760.00 mm Hg (est)
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| Vapor Pressure: | 0.003270 mmHg @ 25.00 °C. |
| Flash Point: | 133.00 °F. TCC ( 56.11 °C. )
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| logP (o/w): | 2.216 (est) |
| Soluble in: |
| | water, 1.39E+04 mg/L @ 25 °C (exp) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-mouse LD50 270 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 26(12), Pg. 22, 1961.
oral-mouse LDLo 5000 mg/kg
Shell Chemical Company. Unpublished Report. Vol. -, Pg. 3, 1961.
intraperitoneal-rat LD50 95 mg/kg
BEHAVIORAL: MUSCLE WEAKNESS
BEHAVIORAL: ATAXIA
American Industrial Hygiene Association Journal. Vol. 19, Pg. 205, 1958.
oral-rat LD50 382 mg/kg
KIDNEY, URETER, AND BLADDER: HEMATURIA
American Industrial Hygiene Association Journal. Vol. 19, Pg. 205, 1958.
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| Dermal Toxicity: |
subcutaneous-mouse LD50 490 mg/kg
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: EXCITEMENT
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 26(12), Pg. 22, 1961.
skin-rabbit LDLo 1200 mg/kg
CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP
BLOOD: CHANGES IN ERYTHROCYTE (RBC) COUNT
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 8(8), Pg. 12, 1964.
skin-rat LD50 500 mg/kg
KIDNEY, URETER, AND BLADDER: HEMATURIA
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Archives of Environmental Health. Vol. 30, Pg. 1, 1975.
subcutaneous-rat LD50 382 mg/kg
"Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 242, 1986.
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| Inhalation Toxicity: |
inhalation-mouse LC50 200 ppm/4H
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
American Industrial Hygiene Association Journal. Vol. 19, Pg. 205, 1958.
inhalation-rat LC50 220 ppm/4H
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
American Industrial Hygiene Association Journal. Vol. 19, Pg. 205, 1958.
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Safety in Use Information:
| Category: | | indirect food additives: adhesives and components of coatings |
| Recommendation for cumene hydroperoxide usage levels up to: | | | not for fragrance use.
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| Recommendation for cumene hydroperoxide flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | cumolhydroperoxide | | | cumyl hydroperoxide | | | cumylhydroperoxide | | a,a- | dimethylbenzyl hydroperoxide | | a,a- | dimethylbenzylhydroperoxide | | | hydroperoxide, 1-methyl-1-phenylethyl | | | hydroperoxide, a,a-dimethylbenzyl | | | hydroperoxide, a,a-dimethylbenzyl- | | 2- | hydroperoxy-2-phenylpropane | | 2- | hydroperoxypropan-2-ylbenzene | | 1- | methyl-1-phenyl ethyl hydroperoxide | | 1- | methyl-1-phenylethyl hydroperoxide | | 1- | methyl-1-phenylethylhydroperoxide | | 2- | phenyl-2-propanyl hydroperoxide | | 2- | phenyl-2-propyl hydroperoxide | | 2- | phenylpropan-2-yl hydroperoxide |
Articles:
| PubMed:In vitro/in vivo screening of oxidative homeostasis and damage to DNA, protein, and lipids using UPLC/MS-MS. |
| PubMed:Homologous overexpression of alkyl hydroperoxide reductase subunit C (ahpC) protects Bifidobacterium longum strain NCC2705 from oxidative stress. |
| PubMed:The importance of Arabidopsis glutathione peroxidase 8 for protecting Arabidopsis plant and E. coli cells against oxidative stress. |
| PubMed:Membranar effects exerted in vitro by polyphenols - quercetin, epigallocatechin gallate and curcumin - on HUVEC and Jurkat cells, relevant for diabetes mellitus. |
| PubMed:Determination of total plasma hydroperoxides using a diphenyl-1-pyrenylphosphine fluorescent probe. |
| PubMed:The role of plasmalogen in the oxidative stability of neutral lipids and phospholipids. |
| PubMed:A search for hepatoprotective activity of aqueous extract of Rhus coriaria L. against oxidative stress cytotoxicity. |
| PubMed:GSTT2, a phase II gene induced by apple polyphenols, protects colon epithelial cells against genotoxic damage. |
| PubMed:Impact of apple polyphenols on GSTT2 gene expression, subsequent protection of DNA and modulation of proliferation using LT97 human colon adenoma cells. |
| PubMed:Efficiency of hemoglobin from rainbow trout, cod, and herring in promotion of hydroperoxide-derived free radicals. |
| PubMed:Heme-mediated production of free radicals via preformed lipid hydroperoxide fragmentation. |
| PubMed:Synthesis and biological evaluation of novel C(6) modified baicalein derivatives as antioxidative agents. |
| PubMed:Amino acid and protein scavenging of radicals generated by iron/hydroperoxide system: an electron spin resonance spin trapping study. |
| PubMed:Role of proteins in oil-in-water emulsions on the stability of lipid hydroperoxides. |
| PubMed:Biochemical characterisation of the recombinant peroxiredoxin (FhePrx) of the liver fluke, Fasciola hepatica. |
| PubMed:SigmaB activation under environmental and energy stress conditions in Listeria monocytogenes. |
| PubMed:The HtrA protease of Campylobacter jejuni is required for heat and oxygen tolerance and for optimal interaction with human epithelial cells. |
| PubMed:Distribution of betalain pigments in red blood cells after consumption of cactus pear fruits and increased resistance of the cells to ex vivo induced oxidative hemolysis in humans. |
| PubMed:RsbT and RsbV contribute to sigmaB-dependent survival under environmental, energy, and intracellular stress conditions in Listeria monocytogenes. |
| PubMed:Effects of released iron, lipid peroxides, and ascorbate in trout hemoglobin-mediated lipid oxidation of washed cod muscle. |
| PubMed:Oxidative stress response of rat testis to model prooxidants in vitro and its modulation. |
| PubMed:Oxidative stress associated DNA damage in testis of mice: induction of abnormal sperms and effects on fertility. |
| PubMed:Effect of natural phenolic acids on DNA oxidation in vitro. |
| PubMed:Role of sigma(B) in heat, ethanol, acid, and oxidative stress resistance and during carbon starvation in Listeria monocytogenes. |
| PubMed:Conjugated triene oxidation products of alpha-farnesene induce symptoms of superficial scald on stored apples. |
| PubMed:Ability of surfactant headgroup size to alter lipid and antioxidant oxidation in oil-in-water emulsions. |
| PubMed:Iron-accelerated cumene hydroperoxide decomposition in hexadecane and trilaurin emulsions. |
| PubMed:Male-mediated dominant lethal mutations in mice following prooxidant treatment. |
| PubMed:Toxicity of linoleic acid hydroperoxide to Saccharomyces cerevisiae: involvement of a respiration-related process for maximal sensitivity and adaptive response. |
| PubMed:Free radical scavenging and antioxidative properties of 'silibin' complexes on microsomal lipid peroxidation. |
| PubMed:Ergosterol oxidation may be considered a signal for fungal growth and aflatoxin production in Aspergillus parasiticus. |
| PubMed:Purification of a cytosolic enzyme from human liver with phospholipid hydroperoxide glutathione peroxidase activity. |
| PubMed:Glutathione content of the small intestine: regulation and function. |
| PubMed:The role of NADPH in the regulation of glucose-6-phosphate and 6-phosphogluconate dehydrogenases in rat adipose tissue. |
| PubMed:Damage to protein synthesis concurrent with lipid peroxidation in rat liver slices: effect of halogenated compounds, peroxides, and vitamin E1. |
| PubMed:Application of simulation modeling to lipid peroxidation processes. |
| PubMed:Peroxides, genes and cancer. |
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3D/inchi