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Category:indirect food additives: adhesives and components of coatings
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.06600 @ 25.00 °C.
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| Refractive Index: | 1.49700 @ 20.00 °C.
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| Flash Point: | > 230.00 °F. TCC ( > 110.00 °C. )
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| Soluble in: |
| | water, 0.1211 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 9900 mg/kg
BEHAVIORAL: FOOD INTAKE (ANIMAL)
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
LIVER: OTHER CHANGES
National Technical Information Service. Vol. OTS000555173
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| Dermal Toxicity: |
skin-rabbit LD > 10000 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: MUSCLE WEAKNESS
BEHAVIORAL: FOOD INTAKE (ANIMAL)
National Technical Information Service. Vol. OTS0555173
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| Inhalation Toxicity: |
inhalation-guinea pig LC50 51 mg/m3/1H
LUNGS, THORAX, OR RESPIRATION: CYANOSIS
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
National Technical Information Service. Vol. OTS0534736
inhalation-rat LCLo 20 ppm/5H
"Documentation of the Threshold Limit Values and Biological Exposure Indices," 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986Vol. 6, Pg. 998, 1991.
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Safety in Use Information:
| Category: | | indirect food additives: adhesives and components of coatings |
| Recommendation for 4,4-methylene bis(cyclohexyl isocyanate) (mixture of isomers) usage levels up to: | | | not for fragrance use.
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| Recommendation for 4,4-methylene bis(cyclohexyl isocyanate) (mixture of isomers) flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 1-iso | cyanato-4-[(4-isocyanatocyclohexyl)methyl]cyclohexane | | bis(4-iso | cyanatocyclohexyl)methane | | | cyclohexane, 1,1'-methylenebis(4-isocyanato- | | | dicyclohexylmethane-4,4'-diisocyanate | | | hydrogenated MDI | | | hylene W | | 1,1- | methylene bis(4-isocyanatocyclohexane) | | 4,4- | methylenebis(cyclohexylisocyanate) | | | nacconate H 12 |
Articles:
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3D/inchi