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Category:flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 97.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.85300 to 0.85700 @ 20.00 °C.
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| Pounds per Gallon - (est).: | 7.106 to 7.139
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| Refractive Index: | 1.40300 to 1.40700 @ 20.00 °C.
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| Boiling Point: | 78.00 to 80.00 °C. @ 760.00 mm Hg
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| Vapor Pressure: | 96.759003 mmHg @ 25.00 °C. (est) |
| Flash Point: | 12.00 °F. TCC ( -11.11 °C. )
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| logP (o/w): | 1.008 (est) |
| Shelf Life: | 6.00 month(s) or longer if stored properly. |
| Storage: | refrigerate in tightly sealed containers. |
| Soluble in: |
| | alcohol | | | water, 8861 mg/L @ 25 °C (est) | | | water, 1.39E+05 mg/L @ 25 °C (exp) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| Substantivity:4 Hour(s) |
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | Xi - Irritant |
R 11 - Highly flammable.
R 19 - May form explosive peroxides.
R 38 - Irritating to skin.
S 02 - Keep out of the reach of children.
S 16 - Keep away from sources of ignition - No Smoking.
S 24/25 - Avoid contact with skin and eyes.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 37/39 - Wear suitable gloves and eye/face protection.
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
skin-rabbit LD50 4500 mg/kg
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 395, 1969.
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| Inhalation Toxicity: |
inhalation-rat LC50 6000 ppm/4H
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 395, 1969.
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Safety in Use Information:
| Category: | | flavoring agents |
| Recommendation for 2-methyl tetrahydrofuran usage levels up to: | | | not for fragrance use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | furan, 2-methyl-tetrahydro- | | | furan, tetrahydro-2-methyl- | | 2- | methyl oxolane | | 2- | methyl-4,5-dihydrofuran | | 2- | methyloxolane | | 2- | methyltetrahydrofuran | | | tetrahydro-2-methyl furan | | | tetrahydro-2-methylfuran | | | tetrahydrofuran, 2-methyl- |
Articles:
| PubMed:Direct Detection of a Triplet Vinylnitrene, 1,4-Naphthoquinone-2- ylnitrene in Solution and Cryogenic Matrices. |
| PubMed:Direct transformation of xylan-type hemicelluloses to furfural via SnCl4 catalysts in aqueous and biphasic systems. |
| PubMed:A "naked" Fe(III)-(O₂²⁻)-Cu(II) species allows for structural and spectroscopic tuning of low-spin heme-peroxo-Cu complexes. |
| PubMed:Hydroxo radicals, C-H activation, and Pt-C bond formation from 77 K photolysis of a platinum(IV) hydroxo complex. |
| PubMed:Highly efficient and enzymatic regioselective undecylenoylation of gastrodin in 2-methyltetrahydrofuran-containing systems. |
| PubMed:Conformational control of oligo(p-phenyleneethynylene)s with intrinsic substituent electronic effects: origin of the twist in pentiptycene-containing systems. |
| PubMed:A unified strategy for iron-catalyzed ortho-alkylation of carboxamides. |
| PubMed:Efficient, solvent-free hydrogenation of α-angelica lactone catalysed by Ru/C at atmospheric pressure and room temperature. |
| PubMed:Photoreduction of Pt(IV) chloro complexes: substrate chlorination by a triplet excited state. |
| PubMed:Highly efficient enzymatic synthesis of an ascorbyl unstaturated fatty acid ester with ecofriendly biomass-derived 2-methyltetrahydrofuran as cosolvent. |
| PubMed:Photophysics of platinum tetrayne oligomers: delocalization of triplet exciton. |
| PubMed:Low-temperature combustion chemistry of novel biofuels: resonance-stabilized QOOH in the oxidation of diethyl ketone. |
| PubMed:Excited state properties of chlorophyll f in organic solvents at ambient and cryogenic temperatures. |
| PubMed:Excitation wavelength dependent O2 release from copper(II)-superoxide compounds: laser flash-photolysis experiments and theoretical studies. |
| PubMed:Measurement of the relative mobility of geminate ions in ethereal solutions of aromatic compounds using the fluorescence response of the solutions to pulsed irradiation. |
| PubMed:High-spin S = 2 ground state aminyl tetraradicals. |
| PubMed:Catalytic transfer hydrogenation/hydrogenolysis for reductive upgrading of furfural and 5-(hydroxymethyl)furfural. |
| PubMed:Stepwise protonation and electron-transfer reduction of a primary copper-dioxygen adduct. |
| PubMed:2-Methyltetrahydrofuran and cyclopentylmethylether: two green solvents for efficient purification of membrane proteins like FhuA. |
| PubMed:Plant-derived juvenile hormone III analogues and other sesquiterpenes from the stem bark of Cananga latifolia. |
| PubMed:U-shaped temperature dependence of rate constant of intramolecular photoinduced charge separation in zinc-porphyrin-bridge-quinone compounds. |
| PubMed:Reaction kinetics of hydrogen abstraction reactions by hydroperoxyl radical from 2-methyltetrahydrofuran and 2,5-dimethyltetrahydrofuran. |
| PubMed:Critical practical aspects in the application of liquid chromatography-mass spectrometric studies for the characterization of impurities and degradation products. |
| PubMed:Chemoselective CaO-mediated acylation of alcohols and amines in 2-methyltetrahydrofuran. |
| PubMed:Highly efficient and regioselective acylation of pharmacologically interesting cordycepin catalyzed by lipase in the eco-friendly solvent 2-methyltetrahydrofuran. |
| PubMed:Enzymatic regioselective acylation of nucleosides in biomass-derived 2-methyltetrahydrofuran: kinetic study and enzyme substrate recognition. |
| PubMed:Mesolysis of radical anions of tetra-, penta-, and hexaphenylethanes. |
| PubMed:Efficient synthesis of phosphatidylserine in 2-methyltetrahydrofuran. |
| PubMed:2-Methyltetrahydrofuran (2-MeTHF): a biomass-derived solvent with broad application in organic chemistry. |
| PubMed:Ligand-localized triplet-state photophysics in a platinum(II) terpyridyl perylenediimideacetylide. |
| PubMed:Intimate electronic coupling in cationic homodimeric iridium(III) complexes. |
| PubMed:Regioselective enzymatic undecylenoylation of 8-chloroadenosine and its analogs with biomass-based 2-methyltetrahydrofuran as solvent. |
| PubMed:Electronic excitation spectra of radical anions of cyanoethylenes and cyanobenzenes: symmetry adapted cluster-configuration interaction study. |
| PubMed:M-M bond-stretching energy landscapes for M2(dimen)4(2+) (M = Rh, Ir; dimen = 1,8-diisocyanomenthane) complexes. |
| PubMed:Intramolecular charge resonance in dimer radical anions of di-, tri-, tetra-, and pentaphenylalkanes. |
| PubMed:Kinetics and thermochemistry of 2,5-dimethyltetrahydrofuran and related oxolanes: next next-generation biofuels. |
| PubMed:Enhanced asymmetric induction for the copolymerization of CO2 and cyclohexene oxide with unsymmetric enantiopure salenCo(III) complexes: synthesis of crystalline CO2-based polycarbonate. |
| PubMed:New method for C-H arylation/alkylation at α-position of cyclic aliphatic ethers by iron-oxide mediated reaction. |
| PubMed:Terpenoids and hexenes from the leaves of Crataegus pinnatifida. |
| PubMed:Direct hydrocyclization of biomass-derived levulinic acid to 2-methyltetrahydrofuran over nanocomposite copper/silica catalysts. |
| PubMed:Strain effects in electron spin resonance spectroscopy of quintet 2,6-bis(4'-nitrenophenyl)-4-phenylpyridine. |
| PubMed:Conformationally constrained macrocyclic diporphyrin-fullerene artificial photosynthetic reaction center. |
| PubMed:Two glass transitions and secondary relaxations of methyltetrahydrofuran in a binary mixture. |
| PubMed:Thermodynamic and molecular-scale analysis of new systems of water-soluble hydrate formers + CH4. |
| PubMed:One-step catalytic transformation of carbohydrates and cellulosic biomass to 2,5-dimethyltetrahydrofuran for liquid fuels. |
| PubMed:Highly luminescent tetradentate bis-cyclometalated platinum complexes: design, synthesis, structure, photophysics, and electroluminescence application. |
| PubMed:Electronic spectra of two long-lived photoproducts: double-proton transfer in 7-hydroxyquinoline dimer in a 2-methyltetrahydrofuran glass matrix. |
| PubMed:Electron spin resonance studies of the reorientational motion of Ni(mnt)2(-). |
| PubMed:Copper(I)/O2 chemistry with imidazole containing tripodal tetradentate ligands leading to mu-1,2-peroxo-dicopper(II) species. |
| PubMed:Molecular structure and magnetic parameters of septet 2,4,6-trinitrenotoluene. |
| PubMed:Temperature dependence of blue phosphorescent cyclometalated Ir(III) complexes. |
| PubMed:A push-pull aromatic chromophore with a touch of merocyanine. |
| PubMed:Syntheses, structural characterization and photophysical properties of 4-(2-pyridyl)-1,2,3-triazole rhenium(I) complexes. |
| PubMed:Triplet formation involving a polar transition state in a well-defined intramolecular perylenediimide dimeric aggregate. |
| PubMed:Unexpectedly similar charge transfer rates through benzo-annulated bicyclo[2.2.2]octanes. |
| PubMed:Theoretical study of pyrazolate-bridged dinuclear platinum(II) complexes: interesting potential energy curve of the lowest energy triplet excited state and phosphorescence spectra. |
| PubMed:Photophysics of diplatinum polyynediyl oligomers: chain length dependence of the triplet state in sp carbon chains. |
| PubMed:Copper(I) complex O(2)-reactivity with a N(3)S thioether ligand: a copper-dioxygen adduct including sulfur ligation, ligand oxygenation, and comparisons with all nitrogen ligand analogues. |
| PubMed:Photophysical properties of highly luminescent copper(I) halide complexes chelated with 1,2-bis(diphenylphosphino)benzene. |
| PubMed:Structures of the hexafluorocyclopropane, octafluorocyclobutane, and decafluorocyclopentane radical anions probed by experimental and computational studies of anisotropic electron spin resonance (ESR) spectra. |
| PubMed:Dioxygen reactivity of a copper(I) complex with a N3S thioether chelate; peroxo-dicopper(II) formation including sulfur-ligation. |
| PubMed:Dual fluorescence from an isonido ReIII rhenacarborane phosphine complex, [7,10-mu-H-7-CO-7,7-(PPh3)2-isonido-7,8,9-ReC2B7H9]. |
| PubMed:Emission spectroscopic investigation of triplet diarylcarbene generated in molecular sieve VPI-5. |
| PubMed:Photoinduced long-lived charge separation in a tetrathiafulvalene-porphyrin-fullerene triad detected by time-resolved electron paramagnetic resonance. |
| PubMed:Dual electron transfer pathways from 4,4'-dimethoxybenzophenone ketyl radical in the excited state to parent molecule in the ground state. |
| PubMed:Ultrafast energy migration in platinum(II) diimine complexes bearing pyrenylacetylide chromophores. |
| PubMed:Structures of tetrafluorocyclopropene, hexafluorocyclobutene, octafluorocyclopentene and related perfluoroalkene radical anions revealed by electron spin resonance spectroscopic and computational studies. |
| PubMed:Conversion of intramolecular singlet electron transfer at room temperature into triplet energy transfer at 77 K: photoisomerization in norbornadiene- and carbazole-labeled poly(aryl ether) dendrimers. |
| PubMed:Synthesis and characterization of ruthenacarborane complexes incorporating chelating N-donor ligands: unexpected luminescence from the complex [3-CO-3,3-kappa2-Me2N(CH2)2NMe2]-closo-3,1,2-RuC2B9H11]. |
| PubMed:Electronic coupling effects on photoinduced electron transfer in carotene-porphyrin-fullerene triads detected by time-resolved EPR. |
| PubMed:Europium(II) and ytterbium(II) cyclic organohydroborates with agostic interactions. |
| PubMed:Photochemistry of 4-(2-nitrophenyl)-1,4-dihydropyridines. Evidence for electron transfer and formation of an intermediate. |
| PubMed:Triplet excitation transfer in glassy systems: spatial and spectral diffusion. |
| PubMed:Platinum(II) 1,10-phenanthroline complexes of acetylides containing redox-active groups. |
| PubMed:Synthesis and characterization of phenanthrylphosphine gold complex: observation of Au-induced blue-green phosphorescence at room temperature. |
| PubMed:Generation and characterization of highly strained dibenzotetrakisdehydro[12]- and dibenzopentakisdehydro[14]annulenes. |
| PubMed:Competition between superexchange-mediated and sequential electron transfer in a bridged donor-acceptor system. |
| PubMed:Dynamics of glass-forming liquids. VIII. Dielectric signature of probe rotation and bulk dynamics in branched alkanes. |
| PubMed:Triplet diphenylcarbenes protected by o-Aryl groups. |
| PubMed:Solvent control of spin-dependent charge recombination mechanisms within donor-conjugated bridge-acceptor molecules. |
| PubMed:Self-assembly of supramolecular light-harvesting arrays from covalent multi-chromophore perylene-3,4:9,10-bis(dicarboximide) building blocks. |
| PubMed:Spin delocalization by triple-bonded functionalities in propargyl and heteropropargyl radicals, assessed from the EPR-spectral D parameter of 1,3-cyclopentanediyl triplet diradicals. |
| PubMed:Excited-state symmetry breaking in cofacial and linear dimers of a green perylenediimide chlorophyll analogue leading to ultrafast charge separation. |
| PubMed:Spin delocalization in 1-heteroallyl monoradicals as a measure of radical stabilization by heterovinyl substituents assessed through the EPR-spectral zero-field D parameter of 1,3-cyclopentanediyl triplet diradicals. |
| PubMed:Hydrogen atom abstraction reactions of charged polyaromatic sigma-radicals related to the active intermediates of the enediyne antitumor drugs. |
| PubMed:The EPR-Spectral D Parameter of Photochemically Generated Cyclopentane-1,3-diyl Triplet Diradicals as a Quantitative Measure of Spin Delocalization in Vinyl-, Phenyl-, and Carbonyl-Substituted Radicals. |
| PubMed:Photoswitched singlet energy transfer in a porphyrin-spiropyran dyad. |
| PubMed:Synthesis and characterization of several dicopper(I) complexes and a spin-delocalized dicopper(I,II) mixed-valence complex using a 1,8-naphthyridine-based dinucleating ligand. |
| PubMed:Driving force and electronic coupling effects on photoinduced electron transfer in a fullerene-based molecular triad |
| PubMed:Steric influence of E- or Z-monosubstituted and terminally disubstituted vinyl groups in matrix-isolated cyclopentane-1,3-diyl triplet diradicals as probed by the zero-field EPR D parameter |
| PubMed:The D parameter of vinyl-substituted 1,3-cyclopentanediyl triplet diradicals as a sensitive tool To determine electronic substituent effects in allylic radicals |
| PubMed:Reactivity of Cl-P(+)-Cl toward cyclic organic ethers. |
| PubMed:The D Parameter (EPR Zero-Field Splitting) of Localized 1,3-Cyclopentanediyl Triplet Diradicals as a Measure of Electronic Substituent Effects on the Spin Densities in Para-Substituted Benzyl-Type Radicals. |
| PubMed:Phosphorescence of nucleic acids and DNA components at 77 K. |
| PubMed:Some aspects of room-temperature phosphorescence in liquid solutions. |
| PubMed:2-methyltetrahydrofuran--lithium hexafluoroarsenate: a superior electrolyte for the secondary lithium electrode. |
| PubMed:EPR study of the effect of concentration on the mechanism of the photochemical reaction of acridine and quinoline with 2-methyltetrahydrofuran. |
| PubMed:Delineation of the intimate details of the backbone conformation of pyridine nucleotide coenzymes in aqueous solution. |
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3D/inchi