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Category:flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 98.00 to 100.00 sum of isomers
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| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.92600 to 0.93700 @ 20.00 °C.
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| Pounds per Gallon - (est).: | 7.714 to 7.806
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| Refractive Index: | 1.46100 to 1.46600 @ 20.00 °C.
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| Boiling Point: | 163.00 to 165.00 °C. @ 760.00 mm Hg
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| Vapor Pressure: | 0.475000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 136.00 °F. TCC ( 58.00 °C. )
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| logP (o/w): | 1.818 (est) |
| Soluble in: |
| | alcohol | | | water, 9140 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| Odor Strength:low |
| Odor Description:at 100.00 %. mild coconut oil |
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intramuscular-mouse LD50 1000 mg/kg
Journal of Scientific and Industrial Research, Section C: Biological Sciences. Vol. 21, Pg. 342, 1962.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | flavoring agents |
| Recommendation for (Z+E)-2-methyl cyclohexanol usage levels up to: | | | not for fragrance use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | cyclohexanol, 2-methyl- | | | hexahydro-o-cresol | | 1- | hydroxy-2-methylcyclohexane | | 2- | methyl cyclohexan-1-ol | | 2- | methyl cyclohexanol | | o- | methyl cyclohexanol | | ortho- | methyl cyclohexanol | | 2- | methyl cyclohexyl alcohol | | 2- | methyl-1-cyclohexanol | | 1- | methyl-2-cyclohexanol | | 2- | methyl-cyclohexan-1-ol | | 2- | methylcyclohexan-1-ol | | (Z+E)-2- | methylcyclohexanol | | 2- | methylcyclohexanol | | o- | methylcyclohexanol | | ortho- | methylcyclohexanol | | 2- | methylcyclohexyl alcohol |
Articles:
| PubMed:Contribution of liver alcohol dehydrogenase to metabolism of alcohols in rats. |
| PubMed:Mechanism of catalytic functionalization of primary C-H bonds using a silylation strategy. |
| PubMed:Effect of ring-constrained phenylpropyloxyethylamines on sigma receptors. |
| PubMed:Camphor modulates TRPV3 cation channels activity by interacting with critical pore-region cysteine residues. |
| PubMed:Simultaneous detection of multiple designer drugs in serum, urine, and CSF in a patient with prolonged psychosis. |
| PubMed:Antidepressant-like effect of 1-(7-methoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-4-YL)-cyclohexanol, a putative trace amine receptor ligand involves l-arginine-nitric oxide-cyclic guanosine monophosphate pathway. |
| PubMed:Cyclohexanol analogues are positive modulators of GABA(A) receptor currents and act as general anaesthetics in vivo. |
| PubMed:Evaluation of antidepressant activity of 1-(7-methoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-4-YL)-cyclohexanol, a β-substituted phenylethylamine in mice. |
| PubMed:Electrochromatographic characterization of methacrylate ester-based monolith and capillary electrochromatography separation of flavonoids. |
| PubMed:Fragment-based screen against HIV protease. |
| PubMed:Preparation and evaluation of the highly cross-linked poly(1-hexadecane-co-trimethylolpropane trimethacrylate) monolithic column for capillary electrochromatography. |
| PubMed:Constitutive activity of cannabinoid-2 (CB2) receptors plays an essential role in the protean agonism of (+)AM1241 and L768242. |
| PubMed:Alkaloid and sesquiterpenes from the root tuber of Curcuma longa. |
| PubMed:Fragrance material review on dihydrocarveol (R,R,R). |
| PubMed:Fragrance material review on dihydrocarveol. |
| PubMed:Biotransformation of (+/-)-2-methylcyclohexanone by fungi. |
| PubMed:Viscosity dependence of the kinetic parameters of the radical ion pair in homogeneous solution determined by optically detected X- and ku-band electron spin resonance. |
| PubMed:Unraveling the reactive species of a functional non-heme iron monooxygenase model using stopped-flow UV-vis spectroscopy. |
| PubMed:Controlling the surface chemistry and chromatographic properties of methacrylate-ester-based monolithic capillary columns via photografting. |
| PubMed:Antiobesity efficacy of a novel cannabinoid-1 receptor inverse agonist, N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-[[5-(trifluoromethyl)pyridin-2-yl]oxy]propanamide (MK-0364), in rodents. |
| PubMed:Differential role of 5-HT1A and 5-HT1B receptors on the antinociceptive and antidepressant effect of tramadol in mice. |
| PubMed:Agonist-directed trafficking of response by endocannabinoids acting at CB2 receptors. |
| PubMed:The endocannabinoid noladin ether acts as a full agonist at human CB2 cannabinoid receptors. |
| PubMed:Role of 5-HT1A and 5-HT1B receptors in the antinociceptive effect of tramadol. |
| PubMed:Discriminative stimulus effects of the structurally novel cannabinoid CB1/CB2 receptor partial agonist BAY 59-3074 in the rat. |
| PubMed:Species comparison and pharmacological characterization of rat and human CB2 cannabinoid receptors. |
| PubMed:Correlation between the physicochemical properties of organic solvents and their biocompatibility toward epoxide hydrolase activity in whole-cells of a yeast, Rhodotorula sp. |
| PubMed:Characterization of cannabinoid modulation of sensory neurotransmission in the rat isolated mesenteric arterial bed. |
| PubMed:Synthesis, structure, and catalytic activity of mononuclear iron and (mu-Oxo)diiron complexes with the ligand 2,6-bis(N-methylbenzimidazol-2-yl)pyridine. |
| PubMed:Fe2+-catalyzed heterolytic RO-OH bond cleavage and substrate oxidation: a functional synthetic non-heme iron monooxygenase system. |
| PubMed:Pharmacological characterisation of cannabinoid receptors inhibiting interleukin 2 release from human peripheral blood mononuclear cells. |
| PubMed:3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB(1) cannabinoid receptor. |
| PubMed:Inhibition of interleukin-8 release in the human colonic epithelial cell line HT-29 by cannabinoids. |
| PubMed:Discriminative stimulus effects of BAY 38-7271, a novel cannabinoid receptor agonist. |
| PubMed:Capillary electrochromatography with monolithic stationary phases: 1. Preparation of sulfonated stearyl acrylate monoliths and their electrochromatographic characterization with neutral and charged solutes. |
| PubMed:"Intermolecular" trapping of a nonheme Fe(IV)=O intermediate. |
| PubMed:Asymmetric synthesis of alpha,alpha-disubstituted alpha-amino acids using (S,S)-cyclohexane-1,2-diol as a chiral auxiliary. |
| PubMed:Synthesis, structure, and H2O2-dependent catalytic functions of disulfide-bridged dicopper(I) and related thioether-copper(I) and thioether-copper(II) complexes. |
| PubMed:Role of hydrogen migration in the mechanism of acetic acid elimination from MH(+) ions of acetates on chemical ionization and collision-induced dissociation |
| PubMed:Assessment of anandamide interaction with the cannabinoid brain receptor: SR 141716A antagonism studies in mice and autoradiographic analysis of receptor binding in rat brain. |
| PubMed:Penicillium discolor, a new species from cheese, nuts and vegetables. |
| PubMed:Applications of High-Temperature Aqueous Media for Synthetic Organic Reactions. |
| PubMed:Pharmacological characterization of three novel cannabinoid receptor agonists in the mouse isolated vas deferens. |
| PubMed:Variation of the alkyl side chain in delta 8-THC. |
| PubMed:Alpha-isoenzyme of alcohol dehydrogenase from monkey liver. Cloning, expression, mechanism, coenzyme, and substrate specificity. |
| PubMed:Neurotoxic metabolites of "commercial hexane" in the urine of shoe factory workers. |
| PubMed:Measurement of the urinary metabolites of N-hexane, cyclohexane and their isomers by gas chromatography. |
| PubMed:A relationship between estrogenicity and antifertility activity of 1-diphenylmethylenyl-2-methyl-3-ethyl-4-acetoxycyclohexane (ORF 8511) and similar nonsteroidal anti-implantive agents. |
| PubMed:[Aminoether derivatives from 2-methylcyclohexanol, menthol and borned]. |
| PubMed:STEREOCHEMICAL ASPECTS OF THE METABOLISM OF THE ISOMERIC METHYLCYCLOHEXANOLS AND METHYLCYCLOHEXANONES. |
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3D/inchi