|
Category:herbicides / pesticides
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
|
| Food Chemicals Codex Listed: | No |
| Melting Point: | 191.00 °C. @ 760.00 mm Hg
|
| Boiling Point: | 323.00 °C. @ 760.00 mm Hg (est)
|
| Flash Point: | 300.00 °F. TCC ( 149.10 °C. ) (est)
|
| logP (o/w): | 2.800 |
| Soluble in: |
| | water, 7 mg/L @ 20 °C (exp) | | | water, 163.6 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-duck LD50 > 2000 mg/kg
Pesticide Manual. Vol. 9, Pg. 265, 1991.
oral-guinea pig LD50 1450 mg/kg
Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 343, 1966.
unreported-mammal (species unspecified) LD50 1500 mg/kg
"Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 87, 1971.
intravenous-mouse LD50 56 mg/kg
U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#03022
oral-mouse LD50 1500 mg/kg
Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 343, 1966.
unreported-mouse LD50 4490 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: ATAXIA
BEHAVIORAL: EXCITEMENT
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 54(11), Pg. 4, 1989.
oral-rat LD50 2400 mg/kg
BEHAVIORAL: ATAXIA
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
BEHAVIORAL: TREMOR
Office of Toxic Substances Report. Vol. OTS
|
| Dermal Toxicity: |
skin-mouse LD50 > 5000 mg/kg
Pesticide Manual. Vol. 9, Pg. 265, 1991.
skin-rabbit LD50 > 2000 mg/kg
Pesticide Manual. Vol. 9, Pg. 265, 1991.
|
| Inhalation Toxicity: |
inhalation-rat LC50 > 21600 mg/m3/1
Pesticide Manual. Vol. 9, Pg. 265, 1991.
|
Safety in Use Information:
| Category: | | herbicides / pesticides |
| Recommendation for dicloran usage levels up to: | | | not for fragrance use.
|
| |
| Recommendation for dicloran flavor usage levels up to: |
| | not for flavor use.
|
Safety References:
European Food Safety Authority (EFSA) reference(s):
|
Reasoned opinion on the review of the existing maximum residue levels (MRLs) for dicloran according to Article 12 of Regulation (EC) No 396/2005
View page or View pdf
|
| EPI System: View |
| NIOSH International Chemical Safety Cards:search |
| Chemical Carcinogenesis Research Information System:Search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| Carcinogenic Potency Database:Search |
| EPA GENetic TOXicology:Search |
| EPA Substance Registry Services (TSCA):99-30-9 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :7430 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:3 |
| 2,6-dichloro-4-nitroaniline |
| Chemidplus:0000099309 |
| RTECS:99-30-9 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | allisan | | | aniline, 2,6-dichloro-4-nitro- | | | batran | | | benzenamine, 2,6-dichloro-4-nitro- | | | botran | | | dichloran | | 2,6- | dichloro-4-nitroaniline | | 2,6- | dichloro-4-nitrobenzenamine | | 2,6- | dichloro-4-nitrophenylamine | | | dicloron | | | resinan | | | resisan |
Articles:
| PubMed:Synthesis and antifungal evaluation of a series of maleimides. |
| PubMed:Community air monitoring for pesticides-part 2: multiresidue determination of pesticides in air by gas chromatography, gas chromatography-mass spectrometry, and liquid chromatography-mass spectrometry. |
| PubMed:Performance and matrix effect observed in QuEChERS extraction and tandem mass spectrometry analyses of pesticide residues in different target crops. |
| PubMed:Evaluation of dicloran's contribution to the mutagenic activity of Cristais River, Brazil, water samples. |
| PubMed:Simultaneous conduction of two- and three-phase hollow-fiber-based liquid-phase microextraction for the determination of aromatic amines in environmental water samples. |
| PubMed:A multi-lysimeter investigation on the mobility and persistence of pesticides in the loam soil of the Fucino Plain (Italy). |
| PubMed:In vivo phosphorylation of regulatory light chain of myosin II in sea urchin eggs and its role in controlling myosin localization and function during cytokinesis. |
| PubMed:p-Nitro-N-propylaniline/silica: synthesis, characterization, and its application in matrix solid phase dispersion for multiresidue analysis of pesticides in carrots. |
| PubMed:Relationship between sampling duration and concentration of culturable airborne mould and bacteria on selected culture media. |
| PubMed:Measurement uncertainty associated with sample processing of oranges and tomatoes for pesticide residue analysis. |
| PubMed:Comparison of different sorbents for multiresidue solid-phase extraction of 16 pesticides from groundwater coupled with high-performance liquid chromatography. |
| PubMed:Characteristics of pesticide pyrotechnic smoke devices. |
| PubMed:Development of selective media for the isolation and enumeration of Alternaria species from soil and plant debris. |
| PubMed:Quality control of Aspergillus flavus and A. parasiticus agar and comparison with dichloran 18% glycerol agar: a collaborative study. |
| PubMed:Cynodontin: a fungal metabolite with antifungal properties. |
| PubMed:Contemporary-use pesticides in personal air samples during pregnancy and blood samples at delivery among urban minority mothers and newborns. |
| PubMed:A more selective medium for Culicinomyces clavisporus. |
| PubMed:[Relationship between salivary lipid peroxidation and the strategy of local dichloran gel treatment for periodontitis]. |
| PubMed:A multi-analyte method for the quantification of contemporary pesticides in human serum and plasma using high-resolution mass spectrometry. |
| PubMed:Comparison of five extraction methods for determination of incurred and added pesticides in dietary composites. |
| PubMed:Mechanisms of resistance to fungicides in field strains of Botrytis cinerea. |
| PubMed:Formulation and evaluation of diclofenac sodium using hydrophilic matrices. |
| PubMed:Comparison of dichloran 18% glycerol (DG18) agar with general purpose mycological media for enumerating food spoilage yeasts. |
| PubMed:Pesticide residues in the Canadian Market Basket Survey--1992 to 1996. |
| PubMed:Determination of fungicides in natural waters using solid-phase microextraction and gas chromatography coupled with electron-capture and mass spectrometric detection. |
| PubMed:A new 2D-TLC bioautography method for the discovery of novel antifungal agents To control plant pathogens. |
| PubMed:Multiresidue analysis of seventeen pesticides in wine by gas chromatography with mass-selective detection. |
| PubMed:A chemostat system for investigating pesticide biodegradation in continuous mixed bacteria cultures originating from surface water. |
| PubMed:A collaborative study on media for the enumeration of yeasts in foods. |
| PubMed:Direct identification of the common cheese contaminant Penicillium commune in factory air samples as an aid to factory hygiene. |
| PubMed:Evaluation of modified dichloran 18% glycerol (DG18) agar for enumerating fungi in wheat flour: a collaborative study. |
| PubMed:Comparison of three selective media for detecting Fusarium species in foods: a collaborative study. |
| PubMed:Residues of dicloran in clingstone peaches after pre- and postharvest application. |
| PubMed:Hormonal regulation of S-adenosylmethionine synthase transcripts in pea ovaries. |
| PubMed:Enhancement by non-mutagenic pesticides of GST-P positive hepatic foci development initiated with diethylnitrosamine in the rat. |
| PubMed:Fungicide inhibition of aflatoxins, diacetoxyscirpenol and zearalenone production. |
| PubMed:Postharvest-applied agrochemicals and their residues in fresh fruits and vegetables. |
| PubMed:Acute toxicity of cadmium, copper, zinc, ammonia, 3,3'-dichlorobenzidine, 2,6-dichloro-4-nitroaniline, methylene chloride, and 2,4,6-trichlorophenol to juvenile grass shrimp and killifish. |
| PubMed:Botran and bleomycin induce crossing-over, and bleomycin also increases aneuploidy in diploid strains of Aspergillus. |
| PubMed:[Biological effect of Botran-75B]. |
| PubMed:Oxidative detection of coulometrically reduced organonitro pesticides in reversed-phase high-performance liquid chromatography. |
| PubMed:Characterization and identification of an indirect cytochrome P-450-initiated denitrosation of 2,6-dichloro-4-nitroaniline in rat hepatic microsomes. |
| PubMed:Selective medium for isolation of Fusarium species and dematiaceous hyphomycetes from cereals. |
| PubMed:Functional expression in Escherichia coli of cloned reovirus S1 gene encoding the viral cell attachment protein sigma 1. |
| PubMed:[Chromatographic methods of determining botran in water, soil and plants]. |
| PubMed:Metabolism of [14C]dichloran (2,6-dichloro-4-nitroaniline) in the lactating goat. |
| PubMed:Anomalous cell wall synthesis in Mucor mucedo (L.) Fres. induced by some fungicides and other compounds related to the problem of dimorphism. |
| PubMed:Dichloran-glycerol medium for enumeration of xerophilic fungi from low-moisture foods. |
| PubMed:Effects of temperature and fungicides on Chrysosporium pannorum (Link) Hughes. |
| PubMed:Effects of fungicides on Aspergillus fumigatus. |
|
3D/inchi