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Category:solvents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless clear viscous liquid (est) |
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.99400 @ 25.00 °C.
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| Refractive Index: | 1.45000 @ 20.00 °C.
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| Melting Point: | -16.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 238.00 to 239.00 °C. @ 760.00 mm Hg
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| Vapor Pressure: | 0.003900 mmHg @ 25.00 °C. |
| Flash Point: | 265.00 °F. TCC ( 129.44 °C. )
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| logP (o/w): | -0.599 (est) |
| Soluble in: |
| | alcohol | | | water, 6.633e+004 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rabbit LD50 6300 mg/kg
BEHAVIORAL: MUSCLE WEAKNESS
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: EXCITEMENT
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 38(9), Pg. 14, 1973.
oral-rat LD50 2000 mg/kg
Journal of Agricultural and Food Chemistry. Vol. 23, Pg. 418, 1975.
oral-mouse LD50 6300 mg/kg
BEHAVIORAL: MUSCLE WEAKNESS
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: EXCITEMENT
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 38(9), Pg. 14, 1973.
intraperitoneal-mouse LD50 2250 mg/kg
Toxicology and Applied Pharmacology. Vol. 49, Pg. 385, 1979.
oral-guinea pig LD50 4600 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: EXCITEMENT
BEHAVIORAL: MUSCLE WEAKNESS
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 38(9), Pg. 14, 1973.
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| Dermal Toxicity: |
skin-rabbit LD50 > 20 ml/kg
Union Carbide Data Sheet. Vol. 5/22/1959
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | solvents |
| Recommendation for 1,5-pentane diol usage levels up to: | | | not for fragrance use.
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| Recommendation for 1,5-pentane diol flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 1,5- | dihydroxypentane | | | pentamethylene glycol | | 1,5- | pentamethylene glycol | | alpha,omega- | pentane diol | | | pentane-1,5-diol | | 1,5- | pentanediol | | alpha,omega- | pentanediol | | 1,5- | pentylene glycol |
Articles:
| PubMed:Contribution of liver alcohol dehydrogenase to metabolism of alcohols in rats. |
| PubMed:Excess enthalpies of mixing, effect of temperature and composition on the density, and viscosity and thermodynamic properties of binary systems of {ammonium-based ionic liquid + alkanediol}. |
| PubMed:Enzymatic production of 5-aminovalerate from L-lysine using L-lysine monooxygenase and 5-aminovaleramide amidohydrolase. |
| PubMed:Tetrabutylammonium bromide (TBABr)-based deep eutectic solvents (DESs) and their physical properties. |
| PubMed:A comparative ultrasonic relaxation study of lower vicinal and terminal alkanediols at 298.15 K in relation to their molecular structure and hydrogen bonding. |
| PubMed:1,3,5-Tri-p-tolyl-pentane-1,5-diol. |
| PubMed:Preliminary crystallographic analysis of a cruciferin protein from seeds of Moringa oleifera. |
| PubMed:Isolation, structure determination, and antiaging effects of 2,3-pentanediol from endophytic fungus of Curcuma amada and docking studies. |
| PubMed:Molybdenum-catalyzed deoxydehydration of vicinal diols. |
| PubMed:Aqueous phase hydrogenation of levulinic acid to 1,4-pentanediol. |
| PubMed:Safety assessment and biological effects of a new cold processed SilEmulsion for dermatological purpose. |
| PubMed:Phase-diagram-guided method for growth of a large crystal of glycoside hydrolase family 45 inverting cellulase suitable for neutron structural analysis. |
| PubMed:Cubic and sponge phases in ether lipid-solvent-water ternary systems: phase behavior and NMR characterization. |
| PubMed:Controlled synthesis of ultrathin lamellar Eu(2)O(3) nanocrystals: self-assembly of 1D nanowires to 2D nanosheets. |
| PubMed:In vivo study of an instantly formed lipid-water cubic phase formulation for efficient topical delivery of aminolevulinic acid and methyl-aminolevulinate. |
| PubMed:Metabolic engineering of Escherichia coli for the production of 5-aminovalerate and glutarate as C5 platform chemicals. |
| PubMed:Catalyst-controlled reversal of chemoselectivity in acylation of 2-aminopentane-1,5-diol derivatives. |
| PubMed:Highly crosslinked polymeric monoliths for reversed-phase capillary liquid chromatography of small molecules. |
| PubMed:Synthesis of high molecular weight polyesters via in vacuo dehydrogenation polymerization of diols. |
| PubMed:Theoretical calculation of the OH vibrational overtone spectra of 1,5-pentanediol and 1,6-hexanediol. |
| PubMed:A Fast Degrading Odd-Odd Aliphatic Polyester-5,7 Made by Condensation Polymerization for Biomedical Applications. |
| PubMed:The preparation of 3-substituted-1,5-dibromopentanes as precursors to heteracyclohexanes. |
| PubMed:Direct catalytic conversion of furfural to 1,5-pentanediol by hydrogenolysis of the furan ring under mild conditions over Pt/Co2AlO4 catalyst. |
| PubMed:The size control of silver nanocrystals with different polyols and its application to low-reflection coating materials. |
| PubMed:Influence of polyols on the formation of iron oxide nanoparticles in solvothermal system. |
| PubMed:A practical total synthesis of (+)-spirolaxine methyl ether. |
| PubMed:Internally protected amino sugar equivalents from enantiopure 1,2-oxazines: synthesis of variably configured carbohydrates with C-branched amino sugar units. |
| PubMed:Allergic contact dermatitis to propyl gallate and pentylene glycol in an emollient cream. |
| PubMed:Lipase-catalyzed regioselective monoacetylation of unsymmetrical 1,5-primary diols. |
| PubMed:Improved synthesis of three methyl-branched pheromone components produced by the female lichen moth. |
| PubMed:Bridged oligonucleotides as molecular probes for investigation of enzyme-substrate interaction and allele-specific analysis of DNA. |
| PubMed:Reactivity of poly-alcohols towards OH, NO3 and SO4- in aqueous solution. |
| PubMed:In vitro activity of chlorhexidine and pentane-1,5-diol and their combination on Candida albicans, Staphylococcus aureus and Propionibacterium acnes. |
| PubMed:1,4-Butanediol content of aqua dots children's craft toy beads. |
| PubMed:Therapeutic effect of 1,5-pentanediol for herpes simplex labialis: a randomized, double-blind, placebo-controlled clinical trial. |
| PubMed:The shape evolution of gold seeds and gold@silver core-shell nanostructures. |
| PubMed:Experimental stroke protection induced by 4-hydroxybenzyl alcohol is cancelled by bacitracin. |
| PubMed:Transferable force field for alcohols and polyalcohols. |
| PubMed:Chemoselective hydrogenolysis of tetrahydrofurfuryl alcohol to 1,5-pentanediol. |
| PubMed:Effect of pentane-1,5-diol and propane-1,2-diol on percutaneous absorption of terbinafine. |
| PubMed:Enantioselective syntheses of both enantiomers of noranabasamine. |
| PubMed:Thermal properties and mixing state of diol-water mixtures studied by calorimetry, large-angle X-ray scattering, and NMR relaxation. |
| PubMed:A comparison of pentane-1,5-diol to other diols for use in dermatology. |
| PubMed:Synthesis of phosphate monomers and bonding to dentin: esterification methods and use of phosphorus pentoxide. |
| PubMed:Allergic contact dermatitis to pentylene glycol in a cosmetic cream. |
| PubMed:[Spectral studies on liquid crystal photoalignment film of photosensitive monomer with fluorinated groups]. |
| PubMed:Polyhedral gold nanocrystals with O h symmetry: from octahedra to cubes. |
| PubMed:Treatment of atopic dermatitis with 1% hydrocortisone and 25% pentane-1,5-diol: effect on Staphylococcus aureus. |
| PubMed:Thermotropic properties of organic nanocrystals embedded in ultrasmall crystallization chambers. |
| PubMed:MD simulations of the binding of alcohols and diols by a calixarene in water: connections between microscopic and macroscopic properties. |
| PubMed:Pentane-1,5-diol as a percutaneous absorption enhancer. |
| PubMed:Total synthesis of the epoxy isoprostane phospholipids PEIPC and PECPC. |
| PubMed:The in vitro activity of pentane-1,5-diol against aerobic bacteria. A new antimicrobial agent for topical usage? |
| PubMed:Removal of lipopolysaccharides from protein-lipopolysaccharide complexes by nonflammable solvents. |
| PubMed:Characterization of European wine glycerol: stable carbon isotope approach. |
| PubMed:Improved assay for determination of busulfan by liquid chromatography using postcolumn photolysis. |
| PubMed:Simple synthesis of beta-D-glycopyranosides using beta-glycosidase from almonds. |
| PubMed:Allergic contact dermatitis from pentylene glycol in an emollient cream, with possible co-sensitization to resveratrol. |
| PubMed:Continuous monitoring of prostatic acid phosphatase using self-indicating substrates. |
| PubMed:Effects of aldehydes and methods of cross-linking on properties of calcium alginate microspheres prepared by emulsification. |
| PubMed:Stereocontrolled total synthesis of the Stemona alkaloid (-)-stenine. |
| PubMed:Volumes of aqueous alcohols, ethers, and ketones to T = 523 K and p = 28 MPa. |
| PubMed:Aerobic and anaerobic metabolism of glutaraldehyde in a river water-sediment system. |
| PubMed:New synthesis of serricornin, the female sex pheromone of the cigarette beetle. |
| PubMed:Ecotoxicology of glutaraldehyde: review of environmental fate and effects studies. |
| PubMed:Determination of leachable components from four commercial dental composites by gas and liquid chromatography/mass spectrometry. |
| PubMed:On protein solubility in organic solvent. |
| PubMed:The effect of pH and temperature on the stability and enzymatic activity of prostatic acid phosphatase. Studies on the optimization of a continuous monitored determination of acid phosphatase, II. |
| PubMed:Effect of ascorbic acid on the metabolism of N-nitrosopiperidine. |
| PubMed:Protection of CGS 10078B against ouabain-induced arrhythmia in the cat. |
| PubMed:[Synthesis of propenol and pentanediol derivatives]. |
| PubMed:Synthesis and antitumor effect of new biological alkylating agents, isethionic acid esters. |
| PubMed:Mutagenicity and alpha-hydroxylation of N-nitrosopyrrolidine and N-nitrosopiperidine: a possible correlation. |
| PubMed:The antimycotic activity in vitro of five diols. |
| PubMed:Permeability of dog lung endothelium to sodium, diols, amides, and water. |
| PubMed:Inhibition of bovine hepatic fructose-1,6-diphosphatase by substrate analogs. |
| PubMed:Action of gamma radiation on liquid 1,5-pentanediol. |
| PubMed:Preparation of dihydropyran delta-hydroxyvaleraldehyde and 1,5-pentanediol from tetrahydrofurfuryl alcohol. |
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3D/inchi