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Category:humectants, skin conditioning
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.04400 @ 25.00 °C.
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| Refractive Index: | 1.47200 @ 20.00 °C.
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| Melting Point: | 8.20 °C. @ 760.00 mm Hg
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| Boiling Point: | 221.00 °C. @ 760.00 mm Hg
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| Vapor Pressure: | 0.100000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 176.00 °F. TCC ( 80.00 °C. )
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| logP (o/w): | -0.030 (est) |
| Soluble in: |
| | water, 9554 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| |
| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-mouse LD50 2840 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION
Journal of Medicinal Chemistry. Vol. 11, Pg. 214, 1968.
oral-rat LD50 1190 uL/kg
SKIN AND APPENDAGES (SKIN): HAIR: OTHER
BEHAVIORAL: TREMOR
SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 1, Pg. 191, 1992.
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| Dermal Toxicity: |
skin-rabbit LD50 930 uL/kg
GASTROINTESTINAL: OTHER CHANGES
GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
BEHAVIORAL: TREMOR
Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 1, Pg. 191, 1992.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | humectants, skin conditioning |
| Recommendation for dimethyl imidazolidinone usage levels up to: | | | not for fragrance use.
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| |
| Recommendation for dimethyl imidazolidinone flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 1,3- | dimethyl-2-imidazolidinone | | 1,3- | dimethylethyleneurea | | N,N'- | dimethylethyleneurea | | 1,3- | dimethylimidazolidin-2-one | | N,N'- | dimethylimidazolidinone | | N,N'- | dimethylimidazolidone | | | karbomos TsEM | | | rhonite 1 |
Articles:
| PubMed:Full evaporation headspace gas chromatography for sensitive determination of high boiling point volatile organic compounds in low boiling matrices. |
| PubMed:Synthesis of 1,2-bis(trimethylsilyl)benzene derivatives from 1,2-dichlorobenzenes using a hybrid metal Mg/CuCl in the presence of LiCl in 1,3-dimethyl-2-imidazolidinone. |
| PubMed:Poly[bis-(1,3-dimethyl-imidazolidin-2-one)(μ2-2,5-dioxidoterephthalato)zirconium(IV)]. |
| PubMed:L-Leucylglycine 0.67-hydrate and [(4S)-2,2-dimethyl-4-(2-methylpropyl)-5-oxoimidazolidin-3-ium-1-yl]acetate. |
| PubMed:Density functional theory study on the reaction mechanism of synthesizing 1,3-dimethyl-2-imidazolidinone by urea method. |
| PubMed:3-{[(4Z)-1,2-Dimethyl-5-oxoimidazol-4-yl-idene]meth-yl}-4-hy-droxy-benzonitrile. |
| PubMed:Zinc-mediated highly α-regioselective prenylation of imines with prenyl bromide. |
| PubMed:Inorganic-organic hybrid materials through post-synthesis modification: Impact of the treatment with azides on the mesopore structure. |
| PubMed:Light-scattering analysis of native wood holocelluloses totally dissolved in LiCl-DMI solutions: high probability of branched structures in inherent cellulose. |
| PubMed:Identification of a higher-order organozincate intermediate involved in Negishi cross-coupling reactions by mass spectrometry and NMR spectroscopy. |
| PubMed:Coefficients of evaporation and gas phase diffusion of low-volatility organic solvents in nitrogen from interferometric study of evaporating droplets. |
| PubMed:In situ diffuse reflectance infrared Fourier transform spectroscopy of MCM-41 mesoporous silica: mechanistic consideration on the chemical fixation of CO2 with N,N'-dimethylethylenediamine to 1,3-dimethyl-2-imidazolidinone. |
| PubMed:Amphiphilic paramagnetic neutral gold dithiolene complexes. |
| PubMed:Mesoporous silica-catalysed continuous chemical fixation of CO(2) with N,N'-dimethylethylenediamine in supercritical CO(2): the efficient synthesis of 1,3-dimethyl-2-imidazolidinone. |
| PubMed:(2R,5S)-5-Benzyl-2,3-dimethyl-4-oxo-2-phenyl-imidazolidin-1-ium chloride. |
| PubMed:Pentakis(trifluoromethyl)phenyl, a sterically crowded and electron-withdrawing group: synthesis and acidity of pentakis(trifluoromethyl)benzene, -toluene, -phenol, and -aniline. |
| PubMed:SEC-MALS-QELS study on the molecular conformation of cellulose in LiCl/amide solutions. |
| PubMed:Matrix media selection for the determination of residual solvents in pharmaceuticals by static headspace gas chromatography. |
| PubMed:Rheological properties and molecular structure of tunicate cellulose in LiCl/1,3-dimethyl-2-imidazolidinone. |
| PubMed:2,2,3-Trisubstituted Tetrahydrofurans and 2H-Tetrahydropyrans by Tandem Demethoxycarbonylation-Michael Addition Reactions. |
| PubMed:1,5-Dimethyl-4-phenylimidazolidin-2-one-derived iminic glycinimides: useful new reagents for practical asymmetric synthesis of alpha-amino acids. |
| PubMed:Synthesis and Physical Properties of Sterically Congested Cycloalkenes, 1,2-Di-tert-butyl-3,3,5,5-tetramethylcyclopentene and 1,2-Di-tert-butyl-3,3,6,6-tetramethylcyclohexene. |
| PubMed:Improved and efficient synthesis of 1alpha-hydroxy-[6-(2)H] and 1alpha-hydroxy-[6,19,19-(2)H]vitamin D3 derivatives. |
| PubMed:Reduced proconvulsant activity of caffeine in rats after a series of electroconvulsive seizures. |
| PubMed:Beta-adrenergic regulation of the eosinophil respiratory burst as detected by lucigenin-dependent luminescence. |
| PubMed:Selective, centrally acting serotonin 5-HT2 antagonists. 2. Substituted 3-(4-fluorophenyl)-1H-indoles. |
| PubMed:K(+)-evoked depolarization stimulates cyclic AMP accumulation in photoreceptor-enriched retinal cell cultures: role of calcium influx through dihydropyridine-sensitive calcium channels. |
| PubMed:Effect of organic N-halamines on selected membrane functions in intact Staphylococcus aureus cells. |
| PubMed:Replacement of carcinogenic solvent HMPA by DMI in insect sex pheromone synthesis. |
| PubMed:Combined halogen disinfectants in poultry processing. |
| PubMed:Potential uses of combined halogen disinfectants in poultry processing. |
| PubMed:The effects of 16,16-dimethyl PGE2 and phosphodiesterase inhibitors on Con A blastogenic responses and NK cytotoxic activity of mouse spleen cells. |
| PubMed:Histamine inhibits activation of human neutrophils and HL-60 leukemic cells via H2-receptors. |
| PubMed:Zetidoline metabolism by rat liver microsomes. Formation of metabolites with potential neuroleptic activity. |
| PubMed:Specificity in enzyme inhibition. 3. Synthesis of 5-substituted 2,2-dimethyl-4-imidazolidinones as inhibitors of tyrosine decarboxylase and histidine decarboxylase. |
| PubMed:Drug-induced alterations in morphology and level of cAMP in cultured human glioma cells. |
| PubMed:Correlation between the carcinogenicities of nitrofuran derivatives and their destructive actions on sebaceous glands of mouse skin. |
| PubMed:[Pharmaceutical studies of imidazolidinone derivatives. V. Stability of 1,2-dimethyl-3-phenyl-4-imidazolidinone and 3-phenyl-4-imidazolidinone in blood]. |
| PubMed:[Pharmaceutical studies of imidazolidinone derivatives. I. Stability of 1,2-dimethyl-3-phenyl-4-imidazolidinone]. |
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3D/inchi