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Category:information only not used for fragrances or flavors
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | water, 2.891e+004 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | information only not used for fragrances or flavors |
| Recommendation for 1,4-pentadien-3-one usage levels up to: | | | not for fragrance use.
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| |
| Recommendation for 1,4-pentadien-3-one flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | divinyl ketone | | | penta-1,4-dien-3-one |
Articles:
| PubMed:Synthesis, anti-tobacco mosaic virus and cucumber mosaic virus activity, and 3D-QSAR study of novel 1,4-pentadien-3-one derivatives containing 4-thioquinazoline moiety. |
| PubMed:Antiviral activity and interaction mechanisms study of novel glucopyranoside derivatives. |
| PubMed:Design, synthesis, antiviral activity and three-dimensional quantitative structure-activity relationship study of novel 1,4-pentadien-3-one derivatives containing the 1,3,4-oxadiazole moiety. |
| PubMed:Synthesis, photophysical studies, solvatochromic analysis and TDDFT calculations of diazaspiro compounds. |
| PubMed:Design, synthesis, and antiviral activity of novel rutin derivatives containing 1, 4-pentadien-3-one moiety. |
| PubMed:Synthesis and antiviral bioactivity of novel 3-((2-((1E,4E)-3-oxo-5-arylpenta-1,4-dien-1-yl)phenoxy)methyl)-4(3H)-quinazolinone derivatives. |
| PubMed:Synthesis and biological evaluation of novel 6-chloro-quinazolin derivatives as potential antitumor agents. |
| PubMed:The role of methoxy group in the Nazarov cyclization of 1,5-bis-(2-methoxyphenyl)-1,4-pentadien-3-one in the gas phase and condensed phase. |
| PubMed:Curcumin analogue identified as hyaluronan export inhibitor by virtual docking to the ABC transporter MRP5. |
| PubMed:Curcumin analog 1, 5-bis (2-trifluoromethylphenyl)-1, 4-pentadien-3-one exhibits enhanced ability on Nrf2 activation and protection against acrolein-induced ARPE-19 cell toxicity. |
| PubMed:Synthesis and antiviral bioactivity of novel (1E, 4E)-1-aryl-5-(2-(quinazolin-4-yloxy)phenyl)-1,4-pentadien-3-one derivatives. |
| PubMed:Construction of α-amido-indanones via formal allenamide hydroacylation-Nazarov cyclization. |
| PubMed:Synthesis of 2-(1,5-diaryl-1,4-pentadien-3-ylidene)-hydrazinecarboximidamide hydrochloride catalyzed by p-dodecylbenzenesulfonic acid in aqueous media under ultrasound irradiation. |
| PubMed:The curcumin analog ca27 down-regulates androgen receptor through an oxidative stress mediated mechanism in human prostate cancer cells. |
| PubMed:New antitumoral agents I: In vitro anticancer activity and in vivo acute toxicity of synthetic 1,5-bis(4-hydroxy-3-methoxyphenyl)-1,4-pentadien-3-one and derivatives. |
| PubMed:Symmetrical alpha-bromoacryloylamido diaryldienone derivatives as a novel series of antiproliferative agents. Design, synthesis and biological evaluation. |
| PubMed:Ultrasound promoted one-pot synthesis of 3-aza-6,10-diaryl-2-oxa-spiro[4.5]decane-1,4,8-trione. |
| PubMed:Evaluation of anti-inflammatory effect of synthetic 1,5-bis(4-acetoxy-3-methoxyphenyl)-1,4-pentadien-3-one, HB2. |
| PubMed:Cyclization of cross-conjugated trienes: the vinylogous Nazarov reaction. |
| PubMed:Curcumin in cancer management: recent results of analogue design and clinical studies and desirable future research. |
| PubMed:[Synthesis and anti-inflammatory activity of hydroxylated E,E-1-(3'-indolyl)-5-(substituted phenyl)-1,4-pentadien-3-one derivatives]. |
| PubMed:Activation of NFkappaB is inhibited by curcumin and related enones. |
| PubMed:Synthesis of 1,1-disubstituted-2,6-diarylcyclohexane-4-ones catalyzed by KF/basic Al2O3 under ultrasound. |
| PubMed:About the conformations of alpha,beta-diunsaturated ketones. |
| PubMed:Discovery of natural products from Curcuma longa that protect cells from beta-amyloid insult: a drug discovery effort against Alzheimer's disease. |
| PubMed:[Not Available]. |
| PubMed:[Reactions of 1,4-pentadien-3-ones. 10. The reaction of 1,5-diphenyl-1,4-pentadien-3-one with malondinitrile]. |
| PubMed:[STUDIES ON NITROFURAN AND RELATED COMPOUNDS FOR MEDICINAL PURPOSE. II. HYDROLYSIS OF 1,5-BIS(5-NITRO-2-FURYL)-1,4-PENTADIEN-3-ONE AMIDINOHYDRAZONE AND ITS CYCLIZED PRODUCT]. |
| PubMed:[STUDIES ON NITROFURAN AND RELATED COMPOUNDS FOR MEDICINAL PURPOSE. I. CYCLIZATION OF 1,5-BIS(5-NITRO-2-FURYL)-1,4-PENTADIEN-3-ONE AMIDINOHYDRAZONE AND RELATED COMPOUNDS]. |
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3D/inchi