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Category:herbicides / pesticides
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 132.80 °C. @ 760.00 mm Hg
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| Boiling Point: | 418.20 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 404.00 °F. TCC ( 206.70 °C. ) (est)
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| logP (o/w): | 3.280 |
| Soluble in: |
| | water, 3.1 mg/L @ 20 °C (exp) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-duck LD50 > 2250 mg/kg
Pesticide Manual. Vol. 9, Pg. 546, 1991.
oral-mouse LD50 > 5000 mg/kg
Pesticide Manual. Vol. 9, Pg. 546, 1991.
oral-quail LD50 > 2250 mg/kg
Pesticide Manual. Vol. 9, Pg. 546, 1991.
oral-rat LD50 > 5000 mg/kg
Pesticide Manual. Vol. 9, Pg. 546, 1991.
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| Dermal Toxicity: |
skin-rat LD50 > 2000 mg/kg
Pesticide Manual. Vol. 9, Pg. 546, 1991.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | herbicides / pesticides |
| Recommendation for mepanipyrim usage levels up to: | | | not for fragrance use.
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| Recommendation for mepanipyrim flavor usage levels up to: |
| | not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
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Reasoned opinion on the modification of the existing maximum residue levels (MRLs) for mepanipyrim in tomato, aubergine, strawberry and cucumber
View page or View pdf
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Modification of the existing maximum residue levels for mepanipyrim in blackberries, raspberries and peppers
View page or View pdf
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Peer review of the pesticide risk assessment of the active substance mepanipyrim
View page or View pdf
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| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :86296 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:2 |
| 4-methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine |
| Chemidplus:0110235477 |
| RTECS:UV6261540 for cas# 110235-47-7 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| N-(4- | methyl-6-prop-1-ynylpyrimidin-2-yl)aniline (IUPAC) | | 4- | methyl-N-phenyl-6-(1-propynyl)-2-pyrimidinamine | | 4- | methyl-N-phenyl-6-prop-1-ynylpyrimidin-2-amine | | 2- | pyrimidinamine, 4-methyl-N-phenyl-6-(1-propynyl)- |
Articles:
| PubMed:Toxicity evaluation of new agricultural fungicides in primary cultured cortical neurons. |
| PubMed:Determination of 28 pesticides applied on two tomato cultivars with a different surface/weight ratio of the berries, using a multiresidue GC-MS/MS method. |
| PubMed:[Determination of six novel amide fungicides in vegetables and fruits by liquid chromatography-tandem mass spectrometry]. |
| PubMed:Influence of new generation fungicides on Saccharomyces cerevisiae growth, grape must fermentation and aroma biosynthesis. |
| PubMed:Single drop microextraction and gas chromatography-mass spectrometry for the determination of diflufenican, mepanipyrim, fipronil, and pretilachlor in water samples. |
| PubMed:Mepanipyrim haptens and antibodies with nanomolar affinity. |
| PubMed:Effect of nonpersistent pesticides on estrogen receptor, androgen receptor, and aryl hydrocarbon receptor. |
| PubMed:Simultaneous determination of pyrimethanil, cyprodinil, mepanipyrim and its metabolite in fresh and home-processed fruit and vegetables by a QuEChERS method coupled with UPLC-MS/MS. |
| PubMed:[Determination of fungicide anilinopyrimidine residues in food by series solid phase extraction-high performance liquid chromatography-tandem mass spectrometry]. |
| PubMed:Planar solid phase extraction clean-up for pesticide residue analysis in tea by liquid chromatography-mass spectrometry. |
| PubMed:Pesticide residues in Portuguese strawberries grown in 2009-2010 using integrated pest management and organic farming. |
| PubMed:Residues behavior of some fungicides applied on two greenhouse tomato varieties different in shape and weight. |
| PubMed:Effect of anilinopyrimidine resistance on aflatoxin production and fitness parameters in Aspergillus parasiticus Speare. |
| PubMed:Metabolism of a fungicide mepanipyrim by soil fungus Cunninghamella elegans ATCC36112. |
| PubMed:Regio- and chemoselective metalation of chloropyrimidine derivatives with TMPMgCl x LiCl and TMP(2)Zn x 2 MgCl(2) x 2 LiCl. |
| PubMed:Evaluation of anilinopyrimidine and other fungicides for control of grey mould (Botrytis cinerea) in container-grown Calluna vulgaris. |
| PubMed:Molecularly imprinted solid-phase extraction method for the high-performance liquid chromatographic analysis of fungicide pyrimethanil in wine. |
| PubMed:Degradation of anilinopyrimidine fungicides photoinduced by iron(III)-polycarboxylate complexes. |
| PubMed:Characterisation by high-performance liquid chromatography-multiple mass spectrometry of intermediate compounds formed from mepanipyrim photoinduced degradation. |
| PubMed:Synthesis and structure-activity study of fungicidal anilinopyrimidines leading to mepanipyrim (KIF-3535) as an anti-Botrytis agent. |
| PubMed:Mepanipyrim, a novel inhibitor of pharmacologically induced Golgi dispersion. |
| PubMed:Pesticide residues in grapes, wine, and their processing products. |
| PubMed:Pesticides in fermentative processes of wine. |
| PubMed:Mepanipyrim, a new fungicide, inhibits intracellular transport of very low density lipoprotein in rat hepatocytes. |
| PubMed:Gas chromatographic determination of azoxystrobin, fluazinam, kresoxim-methyl, mepanipyrim, and tetraconazole in grapes, must, and wine. |
| PubMed:Effects of mepanipyrim on lipid metabolism in rats. |
| PubMed:Mepanipyrim induces fatty liver in rats but not in mice and dogs. |
| PubMed:Effects of mepanipyrim on intracellular trafficking: a comparative study on its effects on exocytic and endocytic trafficking of proteins, sphingolipids, and cholesterol. |
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3D/inchi