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Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | water, 828.2 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| Rosmanol
Odor: characteristic Use: Rosmanol is a novel antioxidant found in Rosemary. |
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for rosmanol usage levels up to: | | | not for fragrance use.
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| Recommendation for rosmanol flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 2H-10,4a-( | epoxymethano)phenanthren-12-one, 1,3,4,9,10,10a-hexahydro-5,6,9-trihydroxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR,9S,10S,10aS)- | | (4bR,8aS,9S,10S)-3,4,10- | trihydroxy-2-isopropyl-8,8-dimethyl-6,7,8,8a,9,10-hexahydro-5H-9,4b-(epoxymethano)phenanthren-12-one |
Articles:
| PubMed:NMR, HS-SPME-GC-MS and HPLC-MS(n) analyses of phytoconstituents and aroma profile of Rosmarinus eriocalyx L. |
| PubMed:Determination and Pharmacokinetic Study of Three Diterpenes in Rat Plasma by UHPLC-ESI-MS/MS after Oral Administration of Rosmarinus officinalis L. Extract. |
| PubMed:Phytochemical Profiling of Flavonoids, Phenolic Acids, Terpenoids, and Volatile Fraction of a Rosemary (Rosmarinus officinalis L.) Extract. |
| PubMed:Antidepressant, Anxiolytic and Antinociceptive Activities of Constituents from Rosmarinus Officinalis. |
| PubMed:Diterpenes from rosemary (Rosmarinus officinalis): Defining their potential for anti-cancer activity. |
| PubMed:New terpenoid glycosides obtained from Rosmarinus officinalis L. aerial parts. |
| PubMed:Relevance of the carnosic acid/carnosol ratio for the level of rosemary diterpene transfer and for improving lamb meat antioxidant status. |
| PubMed:Bioavailability of the major bioactive diterpenoids in a rosemary extract: metabolic profile in the intestine, liver, plasma, and brain of Zucker rats. |
| PubMed:Structure activity relationship of phenolic diterpenes from Salvia officinalis as activators of the nuclear factor E2-related factor 2 pathway. |
| PubMed:Phenolic diterpenes derived from Hyptis incana induce apoptosis and G(2)/M arrest of neuroblastoma cells. |
| PubMed:Role of macrophage CCAAT/enhancer binding protein delta in the pathogenesis of rheumatoid arthritis in collagen-induced arthritic mice. |
| PubMed:Comparison of different extraction procedures for the comprehensive characterization of bioactive phenolic compounds in Rosmarinus officinalis by reversed-phase high-performance liquid chromatography with diode array detection coupled to electrospray time-of-flight mass spectrometry. |
| PubMed:Rosmanol potently induces apoptosis through both the mitochondrial apoptotic pathway and death receptor pathway in human colon adenocarcinoma COLO 205 cells. |
| PubMed:Rosmanol potently inhibits lipopolysaccharide-induced iNOS and COX-2 expression through downregulating MAPK, NF-kappaB, STAT3 and C/EBP signaling pathways. |
| PubMed:Semisynthesis and biological evaluation of abietane-type diterpenes. Revision of the structure of rosmaquinone. |
| PubMed:Neuroprotective and neurotrophic effects of isorosmanol. |
| PubMed:Characterization of two unknown compounds in methanol extracts of rosemary oil. |
| PubMed:[Chemical diversity of the biological active ingredients of salvia officinalis and some closely related species]. |
| PubMed:Abietane diterpenoids from Salvia pachyphylla and S. clevelandii with cytotoxic activity against human cancer cell lines. |
| PubMed:Recovery of antioxidant activity from carnosol quinone: antioxidants obtained from a water-promoted conversion of carnosol quinone. |
| PubMed:Antioxidant activity of organic extracts from aqueous infusions of sage. |
| PubMed:Subcritical water extraction of antioxidant compounds from rosemary plants. |
| PubMed:Recovery mechanism of the antioxidant activity from carnosic acid quinone, an oxidized sage and rosemary antioxidant. |
| PubMed:Antioxidant capacity of abietanes from Sphacele salviae. |
| PubMed:Semisynthesis of rosmanol and its derivatives. Easy access to abietatriene diterpenes isolated from the genus Salvia with biological activities. |
| PubMed:Antioxidant activity of chemical components from sage (Salvia officinalis L.) and thyme (Thymus vulgaris L.) measured by the oil stability index method. |
| PubMed:Antioxidant properties of phenolic diterpenes from Rosmarinus officinalis. |
| PubMed:Apianane terpenoids from Salvia officinalis. |
| PubMed:Response of abietane diterpenes to stress in Rosmarinus officinalis L.: new insights into the function of diterpenes in plants. |
| PubMed:Atmospheric pressure chemical ionization (APcI) liquid chromatography-mass spectrometry: characterization of natural antioxidants. |
| PubMed:Inhibition of lipid peroxidation and superoxide generation by diterpenoids from Rosmarinus officinalis. |
| PubMed:Inhibitory effect of carnosic acid on HIV-1 protease in cell-free assays [corrected]. |
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3D/inchi