2-hydroxy-2-cyclohexenone, 10316-66-2

Supplier Sponsors

Best of Chemicals Supplier
Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services.
BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies.
Email:	Marketing
US Email:	Marketing
Email:	Sales
US Email:	Sales
Voice: 1-631-485-4226
Fax: 1-631-614-7828
US Voice: 1-631-485-4226
US Fax: 1-631-614-7828
Europe	44-203-286-1088
Facebook
Twitter
Linkedin
Blog
Get the App!
CODE103630 CODE103630
Product(s):
10316-66-2 2-Cyclohexen-1-one,2-hydroxy-

R C Treatt and Co Ltd

Innovative ingredient solutions
World-leading innovative ingredient solutions provider for the flavour, fragrance and FMCG industries.
We offer innovative and trend-setting product concepts for our customers, collaborating with them to create true value for their products.
Email:	Enquiries
US Email:	Enquiries
Voice: +44 (0) 1284 702500
Fax: +44 (0) 1284 703809
US Voice: +1 863 668 9500
US Fax: +1 863 668 3388
Twitter
Linkedin
Youtube
News
CODE103630 CODE103630
Product(s):
1,2-Cyclohexanedione NI, Kosher
Used in flavours in bakery and confections at 2ppm, and in meat products soups and sauces at 5ppm.

Name:	2-hydroxycyclohex-2-en-1-one
CAS Number:	10316-66-2	3D/inchi
FDA UNII:	75C1OVW0FJ
Nikkaji Web:	J274.216K
CoE Number:	11046
XlogP3-AA:	0.70 (est)
Molecular Weight:	112.12816000
Formula:	C6 H8 O2
NMR Predictor:	Predict (works with chrome, Edge or firefox)

Category:flavoring agents

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
Google Books:	Search
Google Scholar: with word "volatile"	Search
Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Perfumer and Flavorist:	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search
JECFA Food Flavoring:	424 2-hydroxy-2-cyclohexen-1-one
DG SANTE Food Flavourings:	07.119 2-hydroxycyclohex-2-en-1-one
FEMA Number:	3458 2-hydroxy-2-cyclohexen-1-one
FDA:	No longer provide for the use of these seven synthetic flavoring substances
FDA Mainterm (SATF):	10316-66-2 ; 2-HYDROXY-2-CYCLOHEXEN-1-ONE

Physical Properties:

Appearance:	pale yellow solid (est)
Assay:	99.30 to 100.00
Food Chemicals Codex Listed:	No
Melting Point:	35.00 to 38.00 °C. @ 760.00 mm Hg
Boiling Point:	53.00 °C. @ 2.20 mm Hg
Boiling Point:	256.00 to 257.00 °C. @ 760.00 mm Hg
Vapor Pressure:	0.002000 mmHg @ 25.00 °C. (est)
Flash Point:	184.00 °F. TCC ( 84.44 °C. )
logP (o/w):	-0.742 (est)
Soluble in:
	alcohol
	water
	fats
	water, 9494 mg/L @ 25 °C (est)

Organoleptic Properties:

Flavor Type: caramellic

caramellic

Taste Description: Used in flavours in bakery and confections at 2ppm, and in meat products soups and sauces at 5ppm.caramellic

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

None found

Suppliers:

BOC Sciences

For experimental / research use only.

2-Cyclohexen-1-one,2-hydroxy-

Parchem

2-hydroxy-2-cyclohexenone

R C Treatt & Co Ltd

1,2-Cyclohexanedione

NI, Kosher

Flavor: caramel

Used in flavours in bakery and confections at 2ppm, and in meat products soups and sauces at 5ppm.

Safety Information:


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
flavoring agents
Recommendation for 2-hydroxy-2-cyclohexenone usage levels up to:
	not for fragrance use.

Maximised Survey-derived Daily Intakes (MSDI-EU):		0.049 (μg/capita/day)
Maximised Survey-derived Daily Intakes (MSDI-USA):		0.76 (μg/capita/day)
Structure Class:		II
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 9
Click here to view publication 9
		average usual ppm	average maximum ppm
baked goods:		-	-
beverages(nonalcoholic):		-	-
beverages(alcoholic):		-	-
breakfast cereal:		-	-
cheese:		-	-
chewing gum:		-	-
condiments / relishes:		-	7.00000
confectionery froastings:		-	7.00000
egg products:		-	-
fats / oils:		-	-
fish products:		-	-
frozen dairy:		-	3.00000
fruit ices:		-	3.00000
gelatins / puddings:		-	7.00000
granulated sugar:		-	-
gravies:		-	5.00000
hard candy:		-	-
imitation dairy:		-	-
instant coffee / tea:		-	-
jams / jellies:		-	-
meat products:		-	5.00000
milk products:		-	-
nut products:		-	-
other grains:		-	-
poultry:		-	-
processed fruits:		-	-
processed vegetables:		-	-
reconstituted vegetables:		-	-
seasonings / flavors:		-	-
snack foods:		-	-
soft candy:		-	-
soups:		-	5.00000
sugar substitutes:		-	-
sweet sauces:		-	-

Safety References:

European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...

European Food Safety Authority (EFSA) reference(s):

Flavouring Group Evaluation 213: alpha,beta-Unsaturated alicyclic ketones and precursors from chemical subgroup 2.7 of FGE.19
View page or View pdf

Scientific Opinion on Flavouring Group Evaluation 213, Revision 2 (FGE.213Rev2): Consideration of genotoxic potential for a,�-unsaturated alicyclic ketones and precursors from chemical subgroup 2.7 of FGE.19
View page or View pdf

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :61502

National Institute of Allergy and Infectious Diseases:Data

2-hydroxycyclohex-2-en-1-one

Chemidplus:0010316662

References:

	2-hydroxycyclohex-2-en-1-one
NIST Chemistry WebBook:	Search Inchi
Canada Domestic Sub. List:	10316-66-2
Pubchem (cid):	61502
Pubchem (sid):	135017737

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):	View
HMDB (The Human Metabolome Database):	Search
VCF-Online:	VCF Volatile Compounds in Food
ChemSpider:	View