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Category:flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | white crystalline solid (est) |
| Assay: | 95.00 to 100.00
|
| Food Chemicals Codex Listed: | No |
| Melting Point: | 64.00 to 65.00 °C. @ 760.00 mm Hg
|
| Boiling Point: | 279.00 to 280.00 °C. @ 760.00 mm Hg
|
| Vapor Pressure: | 0.000480 mmHg @ 25.00 °C. (est) |
| Flash Point: | 242.00 °F. TCC ( 116.67 °C. )
|
| logP (o/w): | 4.592 (est) |
| Soluble in: |
| | alcohol | | | water, slightly | | | water, 3.12 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| Odor Description:spicy minty |
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
| Axsyn |
| For experimental / research use only. |
| 1H-Cyclopenta[1,3]cyclopropa[1,2]benzen-3-ol,octahydro-3,7-dimethyl-4-(1-methylethyl)-, (3S,3aR,3bR,4S,7R,7aR)-
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| Parchem |
| cubebol
|
| Chemical Sources Association |
| Need This Item for Flavor/Food?: You can contact the Chemical Sources Association |
Safety Information:
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
|
Not determined
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| Dermal Toxicity: |
|
Not determined
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| Inhalation Toxicity: |
|
Not determined
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Safety in Use Information:
| Category: | | flavoring agents |
| Recommendation for cubebol usage levels up to: | | | not for fragrance use.
|
| |
| Structure Class: | I |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 24 |
| Click here to view publication 24 |
| | average usual ppm | average maximum ppm |
| baked goods: | 1.00000 | 30.00000 |
| beverages(nonalcoholic): | 1.00000 | 30.00000 |
| beverages(alcoholic): | 1.00000 | 30.00000 |
| breakfast cereal: | 1.00000 | 30.00000 |
| cheese: | - | - |
| chewing gum: | 1.00000 | 30.00000 |
| condiments / relishes: | - | - |
| confectionery froastings: | 1.00000 | 30.00000 |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | 1.00000 | 20.00000 |
| fruit ices: | - | - |
| gelatins / puddings: | - | - |
| granulated sugar: | 1.00000 | 20.00000 |
| gravies: | - | - |
| hard candy: | 1.00000 | 20.00000 |
| imitation dairy: | - | - |
| instant coffee / tea: | 1.00000 | 20.00000 |
| jams / jellies: | 1.00000 | 10.00000 |
| meat products: | - | - |
| milk products: | 1.00000 | 10.00000 |
| nut products: | 1.00000 | 10.00000 |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | 1.00000 | 30.00000 |
| soups: | - | - |
| sugar substitutes: | 1.00000 | 30.00000 |
| sweet sauces: | 1.00000 | 30.00000 |
Safety References:
| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :11276107 |
| National Institute of Allergy and Infectious Diseases:Data |
| (3S,3aR,3bR,4S,7R,7aR)-3,7-dimethyl-4-(propan-2-yl)octahydro-1H-cyclopenta[1,3]cyclopropa[1,2]benzen-3-ol |
| Chemidplus:0023445025 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | cubeb camphor | | 1H- | cyclopenta[1,3]cyclopropa[1,2]benzen-3-ol,octahydro-3,7-dimethyl-4-(1-methylethyl)-, (3S,3aR,3bR,4S,7R,7aR)- | | (3S,3aR,3bR,4S,7R,7aR)-3,7- | dimethyl-4-(propan-2-yl)octahydro-1H-cyclopenta[1,3]cyclopropa[1,2]benzen-3-ol | | (3S,3aR,3bR, 4S,7R,7aR)- | octahydro-3,7-dimethyl-4-(1-methyl ethyl)-1H-cyclopenta(1,3)cyclopropa(1,2)benzen-3-ol | | (-)-(1R,4S,5R,6R,7S,10R)-7-iso | propyl-4,10-dimethyl-tricyclo[4.4.0.0(1,5)]decan-4-ol | | (1R,4S,5R,6R,7S,10R)-7-iso | propyl-4,10-dimethyl-tricyclo[4.4.0.0(1,5)]decan-4-ol |
Articles:
| Google Patents:Use of cubebol as a flavoring ingredient |
| PubMed:Essential oil characterization of two Azorean Cryptomeria japonica populations and their biological evaluations. |
| PubMed:Identification of cryptic species within liverwort Conocephalum conicum based on the volatile components. |
| PubMed:[Sesquiterpenes from stem of Schisandra glaucescens]. |
| PubMed:Inter-population variability of terpenoid composition in leaves of Pistacia lentiscus L. from Algeria: a chemoecological approach. |
| PubMed:Sesquiterpene synthases Cop4 and Cop6 from Coprinus cinereus: catalytic promiscuity and cyclization of farnesyl pyrophosphate geometric isomers. |
| PubMed:Enhancement of farnesyl diphosphate pool as direct precursor of sesquiterpenes through metabolic engineering of the mevalonate pathway in Saccharomyces cerevisiae. |
| PubMed:Stereocontrolled syntheses of (-)-cubebol and (-)-10-epicubebol involving intramolecular cyclopropanation of alpha-lithiated epoxides. |
| PubMed:Synthesis of (-)-cubebol by face-selective platinum-, gold-, or copper-catalyzed cycloisomerization: evidence of chirality transfer and mechanistic insights. |
| PubMed:Enhancing sesquiterpene production in Saccharomyces cerevisiae through in silico driven metabolic engineering. |
| PubMed:Mosquito larvicidal activities of extractives from black heartwood-type Cryptomeria japonica. |
| PubMed:Antifeedants against Locusta migratoria from the Japanese Cedar, Cryptomeria japonica II. |
| PubMed:Production of plant sesquiterpenes in Saccharomyces cerevisiae: effect of ERG9 repression on sesquiterpene biosynthesis. |
| PubMed:Synthesis of (-)-cubebol by face-selective platinum-, gold-, or copper-catalyzed cycloisomerization: evidence for chirality transfer. |
| PubMed:Platinum- and gold-catalyzed rearrangement reactions of propargyl acetates: total syntheses of (-)-alpha-cubebene, (-)-cubebol, sesquicarene and related terpenes. |
| PubMed:[Isolation and preparation of sesquiterpenols from the Japanese cedar, Cryptomeria japonica D. Don, by preparative reversed-phase high performance liquid chromatography and its characterization]. |
| PubMed:Antifeedants against Acusta despesta from the Japanese cedar, Cryptomeria japonica II. |
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3D/inchi