adipic acid
hexanedioic acid

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  Beijing Lys Chemicals Co, LTD.

  From Grams to Tons
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  BEIJING LYS CHEMICALS CO, LTD, established in 2004, is a fine chemical high-tech company which contains R&D, production, and sales. We mainly engaged in export and technology development of flavor and fragrance materials and pharmaceutical intermediates. We have nearly 500 kinds of products, from grams to tons, exported to USA, Europe, South Asia and etc. And we custom manufacture new products according to customers’ needs, and serve good quality products and service. Our goal is to become a fine chemical enterprise which could provide special products and services.
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  BOC Sciences

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  Charkit Chemical Corporation

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  about: Since 1982, Charkit has been committed to expanding the markets we serve as our roster of products and services continues to grow with us. Our substantial portfolio of personal care ingredients now include a wide array of luxury and exotic components to compliment the key products we have always offered. We have expanded our offerings to the nutraceutical, industrial, and resin markets with a growing roster of versatile and unique ingredients. We continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions. Please contact us to learn how we can help you reach your goals.
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  Glentham Life Sciences Ltd

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  OQEMA

  With a focus on providing the highest level of service
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  The guiding principles of OQEMA have always been to establish long term relationships with customers and suppliers alike to build sustainable and profitable business for all parties. Through OQEMA’s business divisions the company tailors products and services to better support and service our customers requirements. This structure also allows the company to focus its marketing campaigns more effectively to certain industries. Over the last decade OQEMA has achieved strong growth as a result of the expansion of our business model. Going forward, the company will be expanding this business model into existing and new strategic territories.
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  Penta International Corporation

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  For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes.
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  Sigma-Aldrich

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  Sigma-Aldrich is a leading Life Science and High Technology company dedicated to providing high-quality, safe and certified flavor ingredients with transparent and easily accessible documentation to customers around the globe. Sigma-Aldrich also provides a suite of analytical tools that allow food analysts to simplify sample preparation, cleanup and analysis steps, while increasing sensitivity to trace ingredients and harmful substances to meet regulations and quality standards.
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• 
  TCI AMERICA

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  With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. Over 30,000 Reagents available today in benchtop to bulk quantities. We also offer custom synthesis solutions. Sign up for a TCI account today for fast and free shipping!
  Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose plants enable TCI to offer more than 30,000 products as well as custom synthesis.
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  Tianjin Danjun International Trade Co., LTD.

  Quality Products
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  Tianjin danjun international trade co., LTD. is an organic chemicals trading company approved by the relevant state authorities to register. We have about 300 kinds of products (natural aroma chemicals, synthetic aroma chemicals and pharmaceutical intermediates). Most of the products are used in flavor and fragrance industry. We know the Chinese chemical market well and we have close relationship with many of the main manufacturers, and to provide our customers with quality goods together with comprehensive service.
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  G-071 Adipic acid

Name: hexanedioic acid CAS Number: 124-04-9 3D/inchi Other(deleted CASRN): 1186514-28-2 ECHA EINECS - REACH Pre-Reg: 204-673-3 FDA UNII: 76A0JE0FKJ Nikkaji Web: J10.057I Beilstein Number: 1209788 MDL: MFCD00004420 CoE Number: 26 XlogP3: 0.10 (est) Molecular Weight: 146.14250000 Formula: C6 H10 O4 BioActivity Summary: listing NMR Predictor: Predict (works with chrome, Edge or firefox) EFSA/JECFA Comments: ADI: 0-5 (JECFA, 1978a). Category:flavoring agents and adjuvants, curing and pickling agents, flavor enhancers   US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Google Scholar: Search Google Books: Search Google Scholar: with word "volatile" Search Google Scholar: with word "flavor" Search Google Scholar: with word "odor" Search Perfumer and Flavorist: Search Google Patents: Search US Patents: Search EU Patents: Search Pubchem Patents: Search PubMed: Search NCBI: Search   FDA/DG SANTE Petitions, Reviews, Notices: 184.1009 Adipic acid View - review EU SANCO Adipic acid View - review EU SANCO Adipic acid - adipates View - review JECFA Food Flavoring: 623 adipic acid JECFA Food Additive: Adipic Acid GSFA Codex: Adipic acid (355) DG SANTE Food Flavourings: 08.026 adipic acid DG SANTE Food Additives: adipic acid DG SANTE Food Contact Materials: adipic acid FEMA Number: 2011 adipic acid FDA: No longer provide for the use of these seven synthetic flavoring substances FDA Mainterm (SATF): 124-04-9 ; ADIPIC ACID FDA Regulation: FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS Subpart C--Substances for Use as Components of Coatings Sec. 175.300 Resinous and polymeric coatings. FDA PART 175 -- INDIRECT FOOD ADDITIVES: ADHESIVES AND COMPONENTS OF COATINGS Subpart C--Substances for Use as Components of Coatings Sec. 175.320 Resinous and polymeric coatings for polyolefin films. FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS Subpart B--Substances for Use Only as Components of Paper and Paperboard Sec. 176.170 Components of paper and paperboard in contact with aqueous and fatty foods. FDA PART 176 -- INDIRECT FOOD ADDITIVES: PAPER AND PAPERBOARD COMPONENTS Subpart B--Substances for Use Only as Components of Paper and Paperboard Sec. 176.180 Components of paper and paperboard in contact with dry food. FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact Sec. 177.1200 Cellophane. FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact Sec. 177.1390 Laminate structures for use at temperatures of 250 deg. F and above. FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact Sec. 177.1500 Nylon resins. FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact Sec. 177.1630 Polyethylene phthalate polymers. FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS Subpart B--Substances for Use as Basic Components of Single and Repeated Use Food Contact Sec. 177.1680 Polyurethane resins. FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS Subpart C--Substances for Use Only as Components of Articles Intended for Repeated Use Sec. 177.2420 Polyester resins, cross-linked. FDA PART 177 -- INDIRECT FOOD ADDITIVES: POLYMERS Subpart C--Substances for Use Only as Components of Articles Intended for Repeated Use Sec. 177.2600 Rubber articles intended for repeated use. FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE Subpart B--Listing of Specific Substances Affirmed as GRAS Sec. 184.1009 Adipic acid.   Physical Properties: Appearance: white powder crystals (est) Assay: 99.00 to 100.00 Food Chemicals Codex Listed: Yes Melting Point: 152.00 to 154.00 °C. @ 760.00 mm Hg Boiling Point: 265.00 °C. @ 100.00 mm Hg Boiling Point: 216.00 °C. @ 15.00 mm Hg Vapor Pressure: 1.000000 mmHg @ 159.00 °C. Vapor Density: 5.0 ( Air = 1 ) Flash Point: 385.00 °F. TCC ( 196.11 °C. ) logP (o/w): 0.080 Soluble in:   alcohol   water, hot water   water, slightly soluble in cold water   water, 30800 mg/L @ 34C (exp) Insoluble in:   paraffin oil Similar Items:note butane dicarboxylic anhydride   Organoleptic Properties: Odor Strength:none Odor Description:at 100.00 %. odorless Odor and/or flavor descriptions from others (if found).   Cosmetic Information: CosIng: cosmetic data Cosmetic Uses: buffering agents fragrance   Suppliers: Allan Chemical Adipic Acid Anhui Haibei Hexanedioic Acid Beijing Lys Chemicals Adipic acid BOC Sciences For experimental / research use only. Adipic Acid 95% Charkit Chemical ADIPIC ACID Covalent Chemical Adipic Acid EMD Millipore For experimental / research use only. Adipic Acid sds Glentham Life Sciences Adipic acid Graham Chemical Adipic Acid Kraft Chemical Adipic Acid OQEMA Adipic Acid Penta International ADIPIC ACID NF EP GRADE Penta International ADIPIC ACID NF Penta International ADIPIC ACID Pfaltz & Bauer For experimental / research use only. Adipic acid 99% sds Rainbow Chemical Adipic Acid 99.70 Santa Cruz Biotechnology For experimental / research use only. Adipic Acid Shiva Chemicals and Pharmaceuticals Adipic Acid Sigma-Aldrich Adipic acid, ≥99.5% sds Certified Food Grade Products Silver Fern Chemical Adipic Acid Odor: odorless Use: Adipic Acid is primarily produced for use as a precursor for the production of nylon. Other major applications also involve polymers. Small but significant amounts of Adipic Acid are used as a food ingredient as a flavorant and gelling aid. SysKem Chemie Adipic Acid TCI AMERICA For experimental / research use only. Adipic Acid >99.0%(GC)(T) sds Tianjin Danjun International Adipic acid   Safety Information: Preferred SDS: View European information : Most important hazard(s): Xi - Irritant R 36 - Irritating to eyes. S 02 - Keep out of the reach of children. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36 - Wear suitable protective clothing.   Hazards identification   Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) Serious eye damage (Category 1), H318 Acute aquatic toxicity (Category 3), H402 GHS Label elements, including precautionary statements   Pictogram   Signal word Danger Hazard statement(s) H318 - Causes serious eye damage H402 - Harmful to aquatic life Precautionary statement(s) P273 - Avoid release to the environment. P280 - Wear protective gloves/protective clothing/eye protection/face protection. P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P310 - Immediately call a POISON CENTER or doctor/physician. P501 - Dispose of contents/ container to an approved waste disposal plant. Oral/Parenteral Toxicity: oral-rat LD50 > 11000 mg/kg Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 48(9), Pg. 72, 1983. oral-mouse LD50 [sex: M] 1900 mg/kg Dosed as a 6% suspension in 0.5% methyl cellulose. (Horn et al., 1957) intraperitoneal-rat LD50 275 mg/kg GASTROINTESTINAL: OTHER CHANGES BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BLOOD: HEMORRHAGE Journal of Agricultural and Food Chemistry. Vol. 5, Pg. 759, 1957. oral-rabbit LD50 > 11000 mg/kg Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 48(9), Pg. 72, 1983. intravenous-mouse LD50 680 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BLOOD: HEMORRHAGE Journal of Agricultural and Food Chemistry. Vol. 5, Pg. 759, 1957. oral-mouse LD50 1900 mg/kg GASTROINTESTINAL: OTHER CHANGES Journal of Agricultural and Food Chemistry. Vol. 5, Pg. 759, 1957. Dermal Toxicity: Not determined Inhalation Toxicity: Not determined   Safety in Use Information: Category: flavoring agents and adjuvants, curing and pickling agents, flavor enhancers Recommendation for adipic acid usage levels up to:   not for fragrance use.   Maximised Survey-derived Daily Intakes (MSDI-EU): 11.00 (μg/capita/day) Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library publication number: 3 Click here to view publication 3   average usual ppm average maximum ppm baked goods: - - beverages(nonalcoholic): - 40.00000 beverages(alcoholic): - - breakfast cereal: - - cheese: - - chewing gum: - - condiments / relishes: - - confectionery froastings: - - egg products: - - fats / oils: - - fish products: - - frozen dairy: - - fruit ices: - - gelatins / puddings: - 5000.00000 granulated sugar: - - gravies: - - hard candy: - - imitation dairy: - - instant coffee / tea: - - jams / jellies: - - meat products: - - milk products: - - nut products: - - other grains: - - poultry: - - processed fruits: - - processed vegetables: - - reconstituted vegetables: - - seasonings / flavors: - - snack foods: - - soft candy: - - soups: - - sugar substitutes: - - sweet sauces: - -   Safety References: European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies... European Food Safety Authority (EFSA) reference(s): Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) on a request from the Commission related to - Flavouring Group Evaluation 10: Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - (Commission Regulation (EC) No 1565/2000 of 18 July 2000) View page or View pdf Flavouring Group Evaluation 10, Revision 1 (FGE10 Rev1)[1] - Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC) View page or View pdf Flavouring Group Evaluation 64 (FGE.64): Consideration of aliphatic acyclic diols, triols, and related substances evaluated by JECFA (57th meeting) structurally related to aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 evaluated by EFSA in FGE.10Rev1 (EFSA, 2008ab) View page or View pdf Scientific Report of EFSA on the risk assessment of salts of authorised acids, phenols or alcohols for use in food contact materials [1] View page or View pdf Scientific Opinion on Flavouring Group Evaluation 92 (FGE.92): Consideration of aliphatic acyclic diols, triols, and related substances evaluated by JECFA (68th meeting) structurally related to aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones evaluated by EFSA in FGE.10Rev1 (2009) View page or View pdf Scientific Opinion on Flavouring Group Evaluation 10, Revision 2 (FGE.10Rev2): Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 View page or View pdf Review of substances/agents that have direct beneficial effect on the environment: mode of action and assessment of efficacy View page or View pdf EPI System: View NIOSH International Chemical Safety Cards:search Chemical Carcinogenesis Research Information System:Search AIDS Citations:Search Cancer Citations:Search Toxicology Citations:Search EPA GENetic TOXicology:Search EPA Substance Registry Services (TSCA):124-04-9 EPA ACToR:Toxicology Data EPA Substance Registry Services (SRS):Registry Laboratory Chemical Safety Summary :196 National Institute of Allergy and Infectious Diseases:Data WISER:UN 3077 WGK Germany:1 hexanedioic acid Chemidplus:0000124049 EPA/NOAA CAMEO:hazardous materials RTECS:124-04-9   References:   hexanedioic acid NIST Chemistry WebBook: Search Inchi Canada Domestic Sub. List: 124-04-9 Pubchem (cid): 196 Pubchem (sid): 134974898   Other Information: (IUPAC): Atomic Weights of the Elements 2011 (pdf) Videos: The Periodic Table of Videos tgsc: Atomic Weights use for this web site (IUPAC): Periodic Table of the Elements FDA Substances Added to Food (formerly EAFUS): View FDA Indirect Additives used in Food Contact Substances: View CHEBI: View CHEMBL: View Golm Metabolome Database: Search Metabolomics Database: Search UM BBD: Search KEGG (GenomeNet): C06104 HMDB (The Human Metabolome Database): HMDB00448 FooDB: FDB008309 Export Tariff Code: 2917.12.1000 FDA Listing of Food Additive Status: View VCF-Online: VCF Volatile Compounds in Food ChemSpider: View Wikipedia: View FAO: ADIPIC ACID FAO: Adipic acid Formulations/Preparations: grades: technical; fcc grades of purity: commercial, 99.8% food grades   Potential Blenders and core components note None Found   Potential Uses:   buffering agents   Occurrence (nature, food, other):note   beet juice Search Trop Picture   beet root Search Trop Picture   guava fruit Search Trop Picture   pork fat Search PMC Picture   raspberry red raspberry Search Trop Picture   Synonyms:   acide adipique   acifloctin   acinetten   adi-pure   adilactetten   adipic acid FCC   adipicacid   adipinic acid   asapic 1,4- butane dicarboxylic acid   butane-1,4-dicarboxylic acid 1,4- butanedicarboxylic acid   hexane dioic acid 1,6- hexane dioic acid   hexanedioic acid   hexanedioicacid   inipol DS   Articles: PubMed:The accelerated ripening of cholesterol-reduced Cheddar cheese by crosslinked beta-cyclodextrin. PubMed:[Biosynthesis of adipic acid].

Notes: Constit. of beet juice, pork fat, guava fruit (Psidium guajava), papaya (Carica papaya) and raspberry (Rubus idaeus). Food acidulant Adipic acid is a compound of the class of carboxylic acids that is derived from oxidation of various fats. It is a white crystalline powder appearing as an acid in aqueous circumstances, though it is not highly soluble (wikipedia); Adipic acid, like most carboxylic acids, is a mild skin irritant. It is mildly toxic, with LD50 of 3600 mg/kg for oral ingestion by rats.; By far the majority of the 2.5 billion kg of adipic acid produced annually is used as monomer for the production of nylon by a polycondensation reaction with hexamethylene diamine forming 6,6-nylon. Other major applications also involve polymers: it is a monomer for production of Polyurethane and its esters are plasticizers, especially in PVC.