| Name: | podophyllum peltatum rhizome/root |
| CAS Number: | 90063-90-4 |
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| ECHA EC Number: | 290-050-1 |
| FDA UNII: | Search |
Category:information only not used for fragrances or flavors
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Food Chemicals Codex Listed: | No |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | information only not used for fragrances or flavors |
| Recommendation for podophyllum peltatum rhizome/root usage levels up to: | | | not for fragrance use.
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| Recommendation for podophyllum peltatum rhizome/root flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| Toxicology Citations:Search |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| National Institute of Allergy and Infectious Diseases:Data |
| podophyllum peltatum rhizome/root |
| Chemidplus:0090063904 |
References:
| | podophyllum peltatum rhizome/root |
| Pubchem (sid): | 135304108 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | indian-apple rhizome/root | | wild | jalap rhizome/root | | wild | lemon rhizome/root | | american | mandrake rhizome/root | | wild | mandrake rhizome/root | | | mayapple rhizome/root | | | raccoon-berry rhizome/root |
Articles:
| PubMed:High throughput screening of natural products for anti-mitotic effects in MDA-MB-231 human breast carcinoma cells. |
| PubMed:Next generation sequencing in predicting gene function in podophyllotoxin biosynthesis. |
| PubMed:Plant-associated bacterial populations on native and invasive plant species: comparisons between 2 freshwater environments. |
| PubMed:Taxonomy of mayapple rust: the genus Allodus resurrected. |
| PubMed:Application of ultrasound as pretreatment for extraction of podophyllotoxin from rhizomes of Podophyllum peltatum. |
| PubMed:Rapid analysis of lignans from leaves of Podophyllum peltatum L. samples using UPLC-UV-MS. |
| PubMed:The role of biotechnology in the production of the anticancer compound podophyllotoxin. |
| PubMed:Podophyllum peltatum and observations on the Creek and Cherokee Indians: William Bartram's preservation of Native American pharmacology. |
| PubMed:[Interest of lignans in prevention and treatment of cancers]. |
| PubMed:Cessation of nail growth following Bajiaolian intoxication. |
| PubMed:In vitro propagation of Podophyllum peltatum. |
| PubMed:Endophyte fungal isolates from Podophyllum peltatum produce podophyllotoxin. |
| PubMed:Frequency and timing of leaf removal affect growth and podophyllotoxin content of Podophyllum peltatum in full sun. |
| PubMed:Secoisolariciresinol dehydrogenase: mode of catalysis and stereospecificity of hydride transfer in Podophyllum peltatum. |
| PubMed:Geographic information system method for assessing chemo-diversity in medicinal plants. |
| PubMed:Pharmacy through the ages. Podophyllum peltatum. |
| PubMed:Natural products of plant origin as anticancer agents. |
| PubMed:Myths and mandrakes. |
| PubMed:Podophyllum peltatum possesses a beta-glucosidase with high substrate specificity for the aryltetralin lignan podophyllotoxin. |
| PubMed:Useful plants of dermatology. VI. The mayapple (Podophyllum). |
| PubMed:Evaluation of Podophyllum peltatum accessions for podophyllotoxin production. |
| PubMed:Potent anti-cancer drug from witches' umbrella. |
| PubMed:Aryltetralin lignans: chemistry, pharmacology and biotransformations. |
| PubMed:Heteroblasty and preformation in mayapple, Podophyllum Peltatum (Berberidaceae): developmental flexibility and morphological constraint. |
| PubMed:Secoisolariciresinol dehydrogenase purification, cloning, and functional expression. Implications for human health protection. |
| PubMed:High yield of podophyllotoxin from leaves of Podophyllum peltatum by in situ conversion of podophyllotoxin 4- O-beta-D-glucopyranoside. |
| PubMed:Dirigent-mediated podophyllotoxin biosynthesis in Linum flavum and Podophyllum peltatum. |
| PubMed:Identification and characterization of Podophyllum emodi by API-LC/MS/MS. |
| PubMed:Therapeutic applications of medicinal plants in the treatment of breast cancer: a review of their pharmacology, efficacy and tolerability. |
| PubMed:Podophyllotoxin. |
| PubMed:Podophyllotoxins: current status and recent developments. |
| PubMed:Mandrake toxicity. A case of mistaken identity. |
| PubMed:Nuclear (DNA, RNA, histone and non-histone protein) and nucleolar changes during growth and senescence of may apple leaves. |
| PubMed:Etoposide phosphate: what, why, where, and how? |
| PubMed:Etoposide: a semisynthetic epipodophyllotoxin. Chemistry, pharmacology, pharmacokinetics, adverse effects and use as an antineoplastic agent. |
| PubMed:An investigation of the antiviral activity of Podophyllum peltatum. |
| PubMed:Formation of podophyllotoxins by Podophyllum peltatum tissue cultures. |
| PubMed:Topical treatment of penile condylomata acuminata with podophyllin, podophyllotoxin and colchicine. A comparative study. |
| PubMed:Bridge and fragment aberrations in Podophyllum peltatum. |
| PubMed:[ASTRAGALIN FROM PODOPHYLLUM PELTATUM L. AND P. EMODI WALL]. |
| PubMed:alpha-Peltatin, a new compound isolated from podophyllum peltatum. |
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