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 Category:information only not used for fragrances or flavors 
  
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: 
  
Physical Properties: 
| Food Chemicals Codex Listed:  | No |  
 
  
Organoleptic Properties: 
| Odor and/or flavor descriptions from others (if found). |  
 
  
Cosmetic Information: 
  
Suppliers: 
  
Safety Information: 
|   |  
| Hazards identification |  
|   |  
|  Classification of the substance or mixture |  
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |  
| None found. |  
|  GHS Label elements, including precautionary statements |  
|   |  
| Pictogram |  |  
|   |  
                                                                     
| Hazard statement(s) |  
| None found. |  
| Precautionary statement(s) |  
| None found. |  
| Oral/Parenteral Toxicity:  |  
| 
Not determined
 |  
| Dermal Toxicity:  |  
| 
Not determined
 |  
| Inhalation Toxicity:  |  
| 
Not determined
 |  
 
  
Safety in Use Information: 
| Category:  |  | information only not used for fragrances or flavors |  
| Recommendation for hydrastis canadensis root usage levels up to:  |  |   | not for fragrance use.
 |  
|   |  
| Recommendation for hydrastis canadensis root flavor usage levels up to:  |  
|   | not for flavor use.
 |  
 
  
Safety References: 
  
References: 
|   | hydrastis canadensis root |  
| Pubchem (sid): | 135307822 |  
 
  
Other Information: 
  
Potential Blenders and core components  note 
  
Potential Uses: 
  
Occurrence (nature, food, other): note 
  
Synonyms: 
|   | golden seal root |  |   | goldenseal root |  
 
  
Articles:
| PubMed:Characterization of the alkaloids in goldenseal (Hydrastis canadensis) root by high resolution Orbitrap LC-MS(n). |  
| PubMed:Analysis of goldenseal, Hydrastis canadensis L., and related alkaloids in urine using HPLC with UV detection. |  
| PubMed:Toxicology and carcinogenesis studies of goldenseal root powder (Hydrastis Canadensis) in F344/N rats and B6C3F1 mice (feed studies). |  
| PubMed:Hydrophobic treatment enabling analysis of wettable surfaces using a liquid microjunction surface sampling probe/electrospray ionization-mass spectrometry system. |  
| PubMed:Goldenseal (Hydrastis canadensis L.) extracts synergistically enhance the antibacterial activity of berberine via efflux pump inhibition. |  
| PubMed:Seasonal variation of biomass and bioactive alkaloid content of goldenseal, Hydrastis canadensis. |  
| PubMed:Determination of hydrastine and berberine in goldenseal raw materials, extracts, and dietary supplements by high-performance liquid chromatography with UV: collaborative study. |  
| PubMed:Photochemistry and photocytotoxicity of alkaloids from Goldenseal (Hydrastis canadensis L.) 3: effect on human lens and retinal pigment epithelial cells. |  
| PubMed:Effects of root isoquinoline alkaloids from Hydrastis canadensis on Fusarium oxysporum isolated from Hydrastis root tissue. |  
| PubMed:Photochemistry and photocytotoxicity of alkaloids from Goldenseal (Hydrastis canadensis L.). 2. Palmatine, hydrastine, canadine, and hydrastinine. |  
| PubMed:Capillary zone electrophoresis as a tool for the quality control of goldenseal extracts. |  
| PubMed:Chemical comparison of goldenseal (Hydrastis canadensis L.) root powder from three commercial suppliers. |  
| PubMed:Method validation for determination of alkaloid content in goldenseal root powder. |  
| PubMed:Increased production of antigen-specific immunoglobulins G and M following in vivo treatment with the medicinal plants Echinacea angustifolia and Hydrastis canadensis. |  
| PubMed:Antitubercular natural products: berberine from the roots of commercial Hydrastis canadensis powder. Isolation of inactive 8-oxotetrahydrothalifendine, canadine, beta-hydrastine, and two new quinic acid esters, hycandinic acid esters-1 and -2. |  
 
  
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