| Name: | aframomum melegueta rosc. k. schum. |  
| FDA internal no.:  | 977050-87-5 |  
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| FDA UNII:  | Search |  
| CoE Number: | 15 |  
 
Category:spices, other natural seasonings and flavorings 
  
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: 
  
Physical Properties: 
| Food Chemicals Codex Listed:  | No |  
 
  
Organoleptic Properties: 
| Odor and/or flavor descriptions from others (if found). |  
 
  
Cosmetic Information: 
  
Suppliers: 
  
Safety Information: 
|   |  
| Hazards identification |  
|   |  
|  Classification of the substance or mixture |  
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |  
| None found. |  
|  GHS Label elements, including precautionary statements |  
|   |  
| Pictogram |  |  
|   |  
                                                                     
| Hazard statement(s) |  
| None found. |  
| Precautionary statement(s) |  
| None found. |  
| Oral/Parenteral Toxicity:  |  
| 
Not determined
 |  
| Dermal Toxicity:  |  
| 
Not determined
 |  
| Inhalation Toxicity:  |  
| 
Not determined
 |  
 
  
Safety in Use Information: 
| Category:  |  | spices, other natural seasonings and flavorings |  
| Recommendation for grains of paradise usage levels up to:  |  |   | not for fragrance use.
 |  
|   |  
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |  
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |  
| publication number: 3 |  
| Click here to view publication 3 |  
|   | average usual ppm | average maximum ppm |  
| baked goods:  | - | - |  
| beverages(nonalcoholic):  | - | 43.00000 |  
| beverages(alcoholic):  | - | - |  
| breakfast cereal:  | - | - |  
| cheese:  | - | - |  
| chewing gum:  | - | - |  
| condiments / relishes:  | - | - |  
| confectionery froastings:  | - | - |  
| egg products:  | - | - |  
| fats / oils:  | - | - |  
| fish products:  | - | - |  
| frozen dairy:  | - | 120.00000 |  
| fruit ices:  | - | 120.00000 |  
| gelatins / puddings:  | - | - |  
| granulated sugar:  | - | - |  
| gravies:  | - | - |  
| hard candy:  | - | 120.00000 |  
| imitation dairy:  | - | - |  
| instant coffee / tea:  | - | - |  
| jams / jellies:  | - | - |  
| meat products:  | - | - |  
| milk products:  | - | - |  
| nut products:  | - | - |  
| other grains:  | - | - |  
| poultry:  | - | - |  
| processed fruits:  | - | - |  
| processed vegetables:  | - | - |  
| reconstituted vegetables:  | - | - |  
| seasonings / flavors:  | - | - |  
| snack foods:  | - | - |  
| soft candy:  | - | - |  
| soups:  | - | - |  
| sugar substitutes:  | - | - |  
| sweet sauces:  | - | - |  
 
  
Safety References: 
  
References: 
|   | aframomum melegueta rosc. k. schum. |  
| Pubchem (sid): | 135361286 |  
 
  
Other Information: 
| FDA Substances Added to Food (formerly EAFUS): | View |  
| Export Tariff Code: | 3301.29.6000 |  
| FDA Listing of Food Additive Status: | View |  
| Wikipedia: | View |  
 
  
Potential Blenders and core components  note 
  
Potential Uses: 
  
Occurrence (nature, food, other): note 
  
Synonyms: 
|   | aframomum melegueta rosc. k. schum. |  |   | aframomum meleguetella |  |   | amomum melegueta |  |   | guinea grains |  |   | maniguette seed |  |   | melagueta pepper |  |   | semente do paraiso |  
 
  
Articles:
| PubMed:Protective Effect of Aframomum melegueta phenolics Against CCl4-Induced Rat Hepatocytes Damage; Role of Apoptosis and Pro-inflammatory Cytokines inhibition. |  
| PubMed:Evaluation of the In Vitro and In Vivo Antioxidant Potentials of Aframomum melegueta Methanolic Seed Extract. |  
| PubMed:Daily ingestion of grains of paradise (Aframomum melegueta) extract increases whole-body energy expenditure and decreases visceral fat in humans. |  
| PubMed:In vitro bactericidal activity of diterpenoids isolated from Aframomum melegueta K.Schum against strains of Escherichia coli, Listeria monocytogenes and Staphylococcus aureus. |  
| PubMed:Acute toxicity, biochemical and haematological study of Aframomum melegueta seed oil in male Wistar albino rats. |  
| PubMed:Antioxidant extracts of African medicinal plants induce cell cycle arrest and differentiation in B16F10 melanoma cells. |  
| PubMed:In situ morphometric characterization of Aframomum melegueta accessions in Ghana. |  
| PubMed:Characterization of the spectrum of insecticidal activity of a double-stranded RNA with targeted activity against Western Corn Rootworm (Diabrotica virgifera virgifera LeConte). |  
| PubMed:Grains of paradise (Aframomum melegueta) extract activates brown adipose tissue and increases whole-body energy expenditure in men. |  
| PubMed:Acetylcholinesterase (AChE) inhibitory activity, antioxidant properties and phenolic composition of two Aframomum species. |  
| PubMed:Ethnobotanical study of plants used in treating hypertension in Edo State of Nigeria. |  
| PubMed:Putative mycobacterial efflux inhibitors from the seeds of Aframomum melegueta. |  
| PubMed:Inhibition of key enzymes linked to type 2 diabetes and sodium nitroprusside-induced lipid peroxidation in rat pancreas by water extractable phytochemicals from some tropical spices. |  
| PubMed:Damnacanthal from the Congolese medicinal plant Garcinia huillensis has a potent preferential cytotoxicity against human pancreatic cancer PANC-1 cells. |  
| PubMed:Ghana's herbal market. |  
| PubMed:Spasmolytic effects of aqueous extract of mixture from Aframomumum melegueta (K Schum) - Citrus aurantifolia (Christm and Panzer) on isolated trachea from rat. |  
| PubMed:Hepatoprotective effect of aqueous extract of Aframomum melegueta on ethanol-induced toxicity in rats. |  
| PubMed:Screening for estrogenic and antiestrogenic activities of plants growing in Egypt and Thailand. |  
| PubMed:Effects of the aqueous extract of dry seeds of Aframomum melegueta on some parameters of the reproductive function of mature male rats. |  
| PubMed:Extract of grains of paradise and its active principle 6-paradol trigger thermogenesis of brown adipose tissue in rats. |  
| PubMed:Effect of aqueous extract of alligator pepper (Zingiberaceae aframomum melegueta) on gestational weight gain. |  
| PubMed:Effect of alligator pepper (Zingiberaceae aframomum melegueta) on first trimester pregnancy in Sprague Dawley rats. |  
| PubMed:In vitro inhibitory effect of West African medicinal and food plants on human cytochrome P450 3A subfamily. |  
| PubMed:Toxicological evaluation of grains of paradise (Aframomum melegueta) [Roscoe] K. Schum. |  
| PubMed:Behavioural responses of the maize weevil, Sitophilus zeamais, to host (stored-grain) and non-host plant volatiles. |  
| PubMed:Repellent activity of alligator pepper, Aframomum melegueta, and ginger, Zingiber officinale, against the maize weevil, Sitophilus zeamais. |  
| PubMed:Traditional management of tuberculosis in Ogun State of Nigeria: the practice and ethnobotanical survey. |  
| PubMed:Further pharmacological studies on aqueous seed extract of Aframomum melegueta in rats. |  
| PubMed:Some Nigerian plants of dermatologic importance. |  
| PubMed:Further studies on the antinociceptive action of aqueous seed extract of Aframomum melegueta. |  
| PubMed:Food of paradise: Tahitian breadfruit and the autocritique of European consumption. |  
| PubMed:Antimicrobial activity of some medicinal plants from Ghana. |  
| PubMed:Effects of Aframomum melegueta and Piper guineense on sexual behaviour of male rats. |  
| PubMed:Medicinal and ethnoveterinary remedies of hunters in Trinidad. |  
 
  
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