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Category:cosmetic ingredient for skin conditioning
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | cosmetic ingredient for skin conditioning |
| Recommendation for pentadiplandra brazzeana root extract usage levels up to: | | | not for fragrance use.
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| Recommendation for pentadiplandra brazzeana root extract flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | extract obtained from the roots of pentadiplandra brazzeana, pentadiplandraceae |
Articles:
| PubMed:Potential arms race in the coevolution of primates and angiosperms: brazzein sweet proteins and gorilla taste receptors. |
| PubMed:Chemical composition, in vitro antioxidant and anti-inflammatory properties of essential oils of four dietary and medicinal plants from Cameroon. |
| PubMed:Estrogenic properties of spices of the traditional Cameroonian dish "Nkui" in ovariectomized Wistar rats. |
| PubMed:Potent natural soluble epoxide hydrolase inhibitors from Pentadiplandra brazzeana baillon: synthesis, quantification, and measurement of biological activities in vitro and in vivo. |
| PubMed:Expression of plant sweet protein brazzein in the milk of transgenic mice. |
| PubMed:The structure of brazzein, a sweet-tasting protein from the wild African plant Pentadiplandra brazzeana. |
| PubMed:Multiple mutations of the critical amino acid residues for the sweetness of the sweet-tasting protein, brazzein. |
| PubMed:Temperature-dependent conformational change affecting Tyr11 and sweetness loops of brazzein. |
| PubMed:Stability of benzylic-type isothiocyanates in hydrodistillation-mimicking conditions. |
| PubMed:Efficient production and characterization of the sweet-tasting brazzein secreted by the yeast Pichia pastoris. |
| PubMed:[Optimization of plant des-pGlu1-Brazzein gene according to yeasty biased codons and its expression in Pichia pastoris]. |
| PubMed:Determinants of sweetness in proteins: a topological approach. |
| PubMed:Profile and quantification of glucosinolates in Pentadiplandra brazzeana Baillon. |
| PubMed:Structural role of the terminal disulfide bond in the sweetness of brazzein. |
| PubMed:Key amino acid residues involved in multi-point binding interactions between brazzein, a sweet protein, and the T1R2-T1R3 human sweet receptor. |
| PubMed:Design and evaluation of new analogs of the sweet protein brazzein. |
| PubMed:Interactions between the human sweet-sensing T1R2-T1R3 receptor and sweeteners detected by saturation transfer difference NMR spectroscopy. |
| PubMed:Large increase in brazzein expression achieved by changing the plasmid /strain combination of the NICE system in Lactococcus lactis. |
| PubMed:[Optimizing conditions for the expression of human beta defensin 3 and des-pGlu1-Brazzein in Escherichia coli and analysis of their activity]. |
| PubMed:Direct NMR detection of the binding of functional ligands to the human sweet receptor, a heterodimeric family 3 GPCR. |
| PubMed:Efficient and rapid protein expression and purification of small high disulfide containing sweet protein brazzein in E. coli. |
| PubMed:Optimization of fermentation conditions for the expression of sweet-tasting protein brazzein in Lactococcus lactis. |
| PubMed:Computer simulation and discrete-event models in the analysis of a mammography clinic patient flow. |
| PubMed:Developments in biotechnological production of sweet proteins. |
| PubMed:Interactions of the sweet protein brazzein with the sweet taste receptor. |
| PubMed:[The influences of lactose as an inducer on expression of plant des-pGlu1-brazzein in Escherichia coli]. |
| PubMed:Expression of the sweet-tasting plant protein brazzein in Escherichia coli and Lactococcus lactis: a path toward sweet lactic acid bacteria. |
| PubMed:Probing the sweet determinants of brazzein: wild-type brazzein and a tasteless variant, brazzein-ins(R18a-I18b), exhibit different pH-dependent NMR chemical shifts. |
| PubMed:Brazzein, a small, sweet protein: effects of mutations on its structure, dynamics and functional properties. |
| PubMed:Brazzein a small, sweet protein: discovery and physiological overview. |
| PubMed:Molecular mechanisms of sweet receptor function. |
| PubMed:Sweet proteins--potential replacement for artificial low calorie sweeteners. |
| PubMed:The cysteine-rich region of T1R3 determines responses to intensely sweet proteins. |
| PubMed:Interaction of sweet proteins with their receptor. A conformational study of peptides corresponding to loops of brazzein, monellin and thaumatin. |
| PubMed:Monkey electrophysiological and human psychophysical responses to mutants of the sweet protein brazzein: delineating brazzein sweetness. |
| PubMed:Critical regions for the sweetness of brazzein. |
| PubMed:Correlation of the sweetness of variants of the protein brazzein with patterns of hydrogen bonds detected by NMR spectroscopy. |
| PubMed:Evaluation of androgenic activity of Zingiber officinale and Pentadiplandra brazzeana in male rats. |
| PubMed:Why are sweet proteins sweet? Interaction of brazzein, monellin and thaumatin with the T1R2-T1R3 receptor. |
| PubMed:Characterization of five new low-molecular-mass trypsin inhibitors from white mustard (Sinapis alba L.) seed. |
| PubMed:Sweetness determinant sites of brazzein, a small, heat-stable, sweet-tasting protein. |
| PubMed:Efficient production of recombinant brazzein, a small, heat-stable, sweet-tasting protein of plant origin. |
| PubMed:Urea derivatives from Pentadiplandra brazzeana. |
| PubMed:Solution conformation of brazzein by 1H nuclear magnetic resonance: resonance assignment and secondary structure. |
| PubMed:Complete 1H and partial 13C resonance assignments at 37 and 22 degrees C for brazzein, an intensely sweet protein. |
| PubMed:Solution structure of the thermostable sweet-tasting protein brazzein. |
| PubMed:Synthesis and characterization of the sweet protein brazzein. |
| PubMed:Crystallization and preliminary X-ray analysis of brazzein, a new sweet protein. |
| PubMed:Assignment of the disulfide bonds in the sweet protein brazzein. |
| PubMed:Quantification of cysteinyl sulfhydryl residues in peptides and proteins by ESI-MS or MALDI-MS. |
| PubMed:Quantification of cysteinyl sulfhydryl residues in peptides and proteins by ESI-MS or MALDI-MS. |
| PubMed:Brazzein, a new high-potency thermostable sweet protein from Pentadiplandra brazzeana B. |
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