| PubMed:Phytotherapy And NAFLD - From Goals And Challenges To Clinical Practice. |
| PubMed:Effect of Silitidil, a standardized extract of milk thistle, on the serum prolactin levels in female rats. |
| PubMed:The effects of milk thistle (Silybum marianum) on human cytochrome P450 activity. |
| PubMed:Silymarin and its constituents in cardiac preconditioning. |
| PubMed:New therapeutic potentials of milk thistle (Silybum marianum). |
| PubMed:Anti-aging effects of some selected Iranian folk medicinal herbs-biochemical evidences. |
| PubMed:Flavonolignans from Aspergillus iizukae, a fungal endophyte of milk thistle (Silybum marianum). |
| PubMed:A study on the protective effect of Silybum marianum extract on hepatic ischemia-reperfusion injury. |
| PubMed:Preliminary study about the possible glycemic clinical advantage in using a fixed combination of Berberis aristata and Silybum marianum standardized extracts versus only Berberis aristata in patients with type 2 diabetes. |
| PubMed:Effects of Berberis aristata/Silybum marianum association on metabolic parameters and adipocytokines in overweight dyslipidemic patients. |
| PubMed:Berberis aristata/Silybum marianum fixed combination on lipid profile and insulin secretion in dyslipidemic patients. |
| PubMed:Silibinin meglumine, a water-soluble form of milk thistle silymarin, is an orally active anti-cancer agent that impedes the epithelial-to-mesenchymal transition (EMT) in EGFR-mutant non-small-cell lung carcinoma cells. |
| PubMed:An assessment of pharmacokinetics and antioxidant activity of free silymarin flavonolignans in healthy volunteers: a dose escalation study. |
| PubMed:A systematic approach to evaluate herb-drug interaction mechanisms: investigation of milk thistle extracts and eight isolated constituents as CYP3A inhibitors. |
| PubMed:Semisynthesis, cytotoxicity, antiviral activity, and drug interaction liability of 7-O-methylated analogues of flavonolignans from milk thistle. |
| PubMed:Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence. |
| PubMed:Gemmomodification: an emerging source of natural antioxidants from Silybum marianum. |
| PubMed:Hepatoprotective effect of silyamarin in individuals chronically exposed to hydrogen sulfide; modulating influence of TNF-α cytokine genetic polymorphism. |
| PubMed:Multiclass mycotoxin analysis in Silybum marianum by ultra high performance liquid chromatography-tandem mass spectrometry using a procedure based on QuEChERS and dispersive liquid-liquid microextraction. |
| PubMed:Enhanced bioactivity of silybin B methylation products. |
| PubMed:Effect of topical application of silymarin (Silybum marianum) on excision wound healing in albino rats. |
| PubMed:Potential antioxidant properties and hepatoprotective effects of an aqueous extract formula derived from three Chinese medicinal herbs against CCl(4)-induced liver injury in rats. |
| PubMed:Absolute configuration of isosilybin A by X-ray crystallography of the heavy atom analogue 7-(4-Bromobenzoyl)isosilybin A. |
| PubMed:Silibinin regulates matrix metalloproteinase 3 (stromelysine1) gene expression, hexoseamines and collagen production during rat skin wound healing. |
| PubMed:Pilot study on the additive effects of berberine and oral type 2 diabetes agents for patients with suboptimal glycemic control. |
| PubMed:Silibinin modulates the NF-κb pathway and pro-inflammatory cytokine production by mononuclear cells from preeclamptic women. |
| PubMed:A sensitive LC-MS/MS assay for the simultaneous analysis of the major active components of silymarin in human plasma. |
| PubMed:Amelioration of Ochratoxin A-induced immunotoxic effects by silymarin and Vitamin E in White Leghorn cockerels. |
| PubMed:Formulation of microemulsion systems for dermal delivery of silymarin. |
| PubMed:[Effects of the mixture of Swertia pseudochinensis Hara and Silybum marianum Gaertn extracts on CCl(4)-induced liver injury in rats with non-alcoholic fatty liver disease]. |
| PubMed:Metabolic effects of silibinin in the rat liver. |
| PubMed:The effects of milk thistle on hepatic fibrosis due to methotrexate in rat. |
| PubMed:Silymarin prevents the toxicity induced by benzo(a)pyrene in human erythrocytes by preserving its membrane integrity: an in vitro study. |
| PubMed:The chemopreventive effect of Ginkgo biloba and Silybum marianum extracts on hepatocarcinogenesis in rats. |
| PubMed:A new approach to enhance oral bioavailability of Silybum Marianum dry extract: association of mechanochemical activation and spray congealing. |
| PubMed:Evidence for differences in regioselective and stereoselective glucuronidation of silybin diastereomers from milk thistle (Silybum marianum) by human UDP-glucuronosyltransferases. |
| PubMed:Effects of long-term silymarin oral supplementation on the blood biochemical profile of rainbow trout (Oncorhynchus mykiss). |
| PubMed:[Development of a new HPLC technique for analyzing monosaccharide composition and its application in the quality control of Silybum marianum polysaccharide]. |
| PubMed:The efficacy and safety of herbal medicines used in the treatment of hyperlipidemia; a systematic review. |
| PubMed:Assessment of a dry extract from milk thistle (Silybum marianum) for interference with human liver cytochrome-P450 activities. |
| PubMed:Evaluation of silymarin as a promising radioprotector. |
| PubMed:Milk thistle in liver diseases: past, present, future. |
| PubMed:Multiple effects of silymarin on the hepatitis C virus lifecycle. |
| PubMed:Anti-apoptotic and anti-inflammatory effects of Silybum marianum in treatment of experimental steatohepatitis. |
| PubMed:The effect of silybin on passive avoidance learning and pathological changes in hippocampal CA1 and DG regions in male Wistar rats offspring. |
| PubMed:Comparison of Silybum marianum (L.) Gaertn. with fluoxetine in the treatment of Obsessive-Compulsive Disorder. |
| PubMed:Silymarin, the antioxidant component and Silybum marianum extracts prevent liver damage. |
| PubMed:Large-scale isolation of flavonolignans from Silybum marianum extract affords new minor constituents and preliminary structure-activity relationships. |
| PubMed:Two flavonolignans from milk thistle (Silybum marianum) inhibit CYP2C9-mediated warfarin metabolism at clinically achievable concentrations. |
| PubMed:Silymarin inhibits in vitro T-cell proliferation and cytokine production in hepatitis C virus infection. |
| PubMed:Optimisation of enzyme assisted extraction of silybin from the seeds of Silybum marianum by Box-Behnken experimental design. |
| PubMed:Silymarin BIO-C, an extract from Silybum marianum fruits, induces hyperprolactinemia in intact female rats. |
| PubMed:A randomized controlled trial to assess the safety and efficacy of silymarin on symptoms, signs and biomarkers of acute hepatitis. |
| PubMed:Clinical efficacy, safety and tolerability of BIO-C (micronized Silymarin) as a galactagogue. |
| PubMed:Solid state mechanochemical activation of Silybum marianum dry extract with betacyclodextrins: Characterization and bioavailability of the coground systems. |
| PubMed:In vitro antioxidant activity of silymarin. |
| PubMed:[Influence of silymarin and doxorubicin on the myocardial function in rats]. |
| PubMed:Hepatic metabolism and biliary excretion of silymarin flavonolignans in isolated perfused rat livers: role of multidrug resistance-associated protein 2 (Abcc2). |
| PubMed:Silymarin attenuated mast cell recruitment thereby decreased the expressions of matrix metalloproteinases-2 and 9 in rat liver carcinogenesis. |
| PubMed:Solid state mechanochemical simultaneous activation of the constituents of the Silybum marianum phytocomplex with crosslinked polymers. |
| PubMed:Effects of silymarin on the resolution of liver fibrosis induced by carbon tetrachloride in rats. |
| PubMed:An updated systematic review with meta-analysis for the clinical evidence of silymarin. |
| PubMed:Some common signal transduction events are not necessary for the elicitor-induced accumulation of silymarin in cell cultures of Silybum marianum. |
| PubMed:In vitro evaluation and pharmacokinetics in dogs of solid dispersion pellets containing Silybum marianum extract prepared by fluid-bed coating. |
| PubMed:Clinical assessment of CYP2D6-mediated herb-drug interactions in humans: effects of milk thistle, black cohosh, goldenseal, kava kava, St. John's wort, and Echinacea. |
| PubMed:Pressurized water versus ethanol as a Silybum marianum extraction solvent for inhibition of low-density lipoprotein oxidation mediated by copper and J774 macrophage cells. |
| PubMed:Immunosuppressive effect of silibinin in experimental autoimmune encephalomyelitis. |
| PubMed:Flavonoid, silibinin, inhibits proliferation and promotes cell-cycle arrest of human colon cancer. |
| PubMed:Gram-scale purification of flavonolignan diastereoisomers from Silybum marianum (Milk Thistle) extract in support of preclinical in vivo studies for prostate cancer chemoprevention. |
| PubMed:Pharmacokinetics and metabolic profile of free, conjugated, and total silymarin flavonolignans in human plasma after oral administration of milk thistle extract. |
| PubMed:The potential of milk thistle (Silybum marianum L.), an Israeli native, as a source of edible sprouts rich in antioxidants. |
| PubMed:Silybin is metabolized by cytochrome P450 2C8 in vitro. |
| PubMed:Use of Silybum marianum fruit extract in broiler chicken nutrition: influence on performance and meat quality. |
| PubMed:Inhibition of T-cell inflammatory cytokines, hepatocyte NF-kappaB signaling, and HCV infection by standardized Silymarin. |
| PubMed:Metabolomic alterations in elicitor treated Silybum marianum suspension cultures monitored by nuclear magnetic resonance spectroscopy. |
| PubMed:Antioxidant capacity of 55 medicinal herbs traditionally used to treat the urinary system: a comparison using a sequential three-solvent extraction process. |
| PubMed:The efficacy of Silybum marianum (L.) Gaertn. (silymarin) in the treatment of type II diabetes: a randomized, double-blind, placebo-controlled, clinical trial. |
| PubMed:Influence of silymarin and its flavonolignans on H(2)O(2)-induced oxidative stress in human keratinocytes and mouse fibroblasts. |
| PubMed:Does Silybum marianum play a role in the treatment of chronic hepatitis C? |
| PubMed:Evaluation of hybrid liposomes-encapsulated silymarin regarding physical stability and in vivo performance. |
| PubMed:[The use of flavolignans of "Silybum marianum (L.) Gaertn." to create a new fat product--fortified butter]. |
| PubMed:A silychristin isomer and variation of flavonolignan levels in milk thistle (Silybum marianum) fruits. |
| PubMed:Herbal medicines for liver diseases. |
| PubMed:A review of the bioavailability and clinical efficacy of milk thistle phytosome: a silybin-phosphatidylcholine complex (Siliphos). |
| PubMed:Yeast extract and methyl jasmonate-induced silymarin production in cell cultures of Silybum marianum (L.) Gaertn. |
| PubMed:Efficacy of silymarin-phospholipid complex in reducing the toxicity of aflatoxin B1 in broiler chicks. |
| PubMed:Silymarin, a possible hepatoprotector in dairy cows: biochemical and histological observations. |
| PubMed:Chemoprotective effect of plant phenolics against anthracycline-induced toxicity on rat cardiomyocytes. Part I. Silymarin and its flavonolignans. |
| PubMed:Silibinin protects mice from T cell-dependent liver injury. |
| PubMed:[St. Mary's Thistle: an overview]. |
| PubMed:Primary cultures of human hepatocytes as a tool in cytotoxicity studies: cell protection against model toxins by flavonolignans obtained from Silybum marianum. |
| PubMed:Immunostimulatory effect of Silybum Marianum (milk thistle) extract. |
| PubMed:Effect of silybin and its congeners on human liver microsomal cytochrome P450 activities. |
| PubMed:Neurotrophic and neuroprotective effects of milk thistle (Silybum marianum) on neurons in culture. |
| PubMed:Influence of silymarin and its flavonolignans on doxorubicin-iron induced lipid peroxidation in rat heart microsomes and mitochondria in comparison with quercetin. |
| PubMed:["Silymarin"--an extract from the milk thistle (Silybum marianum)--is it a drug or nutritional supplement?]. |
| PubMed:Evaluation of the immunomodulatory effects of five herbal plants. |
| PubMed:Biologically active compounds of Helichrysum arenarium (L.) Moench. |
| PubMed:Determination of silymarine in the extract from the dried silybum marianum fruits by high performance liquid chromatography and capillary electrophoresis. |
| PubMed:Activities of silymarin and its flavonolignans upon low density lipoprotein oxidizability in vitro. |
| PubMed:A review of plants used in the treatment of liver disease: part two. |
| PubMed:Effect of the flavanolignans of Silybum marianum L. on lipid peroxidation in rat liver microsomes and freshly isolated hepatocytes. |
| PubMed:[High-performance liquid chromatographic separation of silymarins and their determination in a raw extract of Silybum marianum Gaertn]. |
