| PubMed:Effect of UDP-Glucuronosyltransferase (UGT) 1A Polymorphism (rs8330 and rs10929303) on Glucuronidation Status of Acetaminophen. |
| PubMed:Race, Gender, and Genetic Polymorphism Contribute to Variability in Acetaminophen Pharmacokinetics, Metabolism, and Protein-Adduct Concentrations in Healthy African-American and European-American Volunteers. |
| PubMed:A method for evaluating the pharmaceutical deconjugation potential in river water environments. |
| PubMed:Quantitative Method for Simultaneous Analysis of Acetaminophen and 6 Metabolites. |
| PubMed:Neonatal Maturation of Paracetamol (Acetaminophen) Glucuronidation, Sulfation, and Oxidation Based on a Parent-Metabolite Population Pharmacokinetic Model. |
| PubMed:Detection of pharmaceuticals and phytochemicals together with their metabolites in hospital effluents in Japan, and their contribution to sewage treatment plant influents. |
| PubMed:Simultaneous quantification of acetaminophen and five acetaminophen metabolites in human plasma and urine by high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry: Method validation and application to a neonatal pharmacokinetic study. |
| PubMed:Tracer-based assessments of hepatic anaplerotic and TCA cycle flux: practicality, stoichiometry, and hidden assumptions. |
| PubMed:Developmental changes rather than repeated administration drive paracetamol glucuronidation in neonates and infants. |
| PubMed:Favipiravir inhibits acetaminophen sulfate formation but minimally affects systemic pharmacokinetics of acetaminophen. |
| PubMed:Simplified analysis of acetaminophen glucuronide for quantifying gluconeogenesis and glycogenolysis using deuterated water. |
| PubMed:Altered regulation of hepatic efflux transporters disrupts acetaminophen disposition in pediatric nonalcoholic steatohepatitis. |
| PubMed:Establishment of a model of acetaminophen-induced hepatotoxicity in different weekly-aged ICR mice. |
| PubMed:An open label pilot study to evaluate the efficacy of Spanish black radish on the induction of phase I and phase II enzymes in healthy male subjects. |
| PubMed:Magnetic beads as an extraction medium for simultaneous quantification of acetaminophen and structurally related compounds in human serum. |
| PubMed:Population pharmacokinetics of intravenous acetaminophen and its metabolites in major surgical patients. |
| PubMed:The effect of sunitinib on the plasma exposure of intravenous paracetamol and its major metabolite: paracetamol glucuronide. |
| PubMed:Detection and follow-up, after partial liver resection, of the urinary paracetamol metabolites by proton NMR spectroscopy. |
| PubMed:Changes in pharmacokinetic profiles of acetaminophen and its glucuronide after pretreatment with combinations of N-acetylcysteine and either glycyrrhizin, silibinin or spironolactone in rat. |
| PubMed:Simultaneous quantification of acetaminophen and structurally related compounds in human serum and plasma. |
| PubMed:The effect of aging on acetaminophen pharmacokinetics, toxicity and Nrf2 in Fischer 344 rats. |
| PubMed:Development of a simple analytical method for the simultaneous determination of paracetamol, paracetamol-glucuronide and p-aminophenol in river water. |
| PubMed:Effect of excipients on acetaminophen metabolism and its implications for prevention of liver injury. |
| PubMed:Consumption and occurrence of pharmaceutical and personal care products in the aquatic environment in Spain. |
| PubMed:The pharmacokinetic profile of intravenous paracetamol in adult patients undergoing major abdominal surgery. |
| PubMed:Acetaminophen glucuronide and plasma glucose report identical estimates of gluconeogenesis and glycogenolysis for healthy and prediabetic subjects using the deuterated water method. |
| PubMed:Quantification of acetaminophen and two of its metabolites in human plasma by ultra-high performance liquid chromatography-low and high resolution tandem mass spectrometry. |
| PubMed:Pharmacokinetics of paracetamol and its metabolites in women at delivery and post-partum. |
| PubMed:Simultaneous LC-MS/MS quantitation of acetaminophen and its glucuronide and sulfate metabolites in human dried blood spot samples collected by subjects in a pilot clinical study. |
| PubMed:Pharmacokinetics and ocular disposition of paracetamol and paracetamol glucuronide in rabbits with diabetes mellitus induced by alloxan. |
| PubMed:Severe diabetes and leptin resistance cause differential hepatic and renal transporter expression in mice. |
| PubMed:Investigating paracetamol pharmacokinetics using venous and capillary blood and saliva sampling. |
| PubMed:Simultaneous quantitative determination of paracetamol and its glucuronide conjugate in human plasma and urine by liquid chromatography coupled to electrospray tandem mass spectrometry: application to a clinical pharmacokinetic study. |
| PubMed:Can a cocktail designed for phenotyping pharmacokinetics and metabolism enzymes in human be used efficiently in rat? |
| PubMed:Imitation of drug metabolism in human liver and cytotoxicity assay using a microfluidic device coupled to mass spectrometric detection. |
| PubMed:Exacerbation of acetaminophen hepatotoxicity by the anthelmentic drug fenbendazole. |
| PubMed:UDP-glucuronosyltransferase expression in mouse liver is increased in obesity- and fasting-induced steatosis. |
| PubMed:Pharmacokinetics of intravenous paracetamol in elderly patients. |
| PubMed:Acetaminophen pharmacokinetics in children with nonalcoholic fatty liver disease. |
| PubMed:Evaluating human liver reserve function by measuring serum concentrations of phenacetin and its metabolites. |
| PubMed:Species comparison of oral bioavailability, first-pass metabolism and pharmacokinetics of acetaminophen. |
| PubMed:Drugs, bugs, and personalized medicine: pharmacometabonomics enters the ring. |
| PubMed:Studies of acetaminophen and metabolites in urine and their correlations with toxicity using metabolomics. |
| PubMed:Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism. |
| PubMed:The effect of transcatheter arterial chemoembolization on phase II drug metabolism enzymes in patients with hepatocellular carcinoma. |
| PubMed:In vivo glucuronidation activity of drugs in neonates: extensive interindividual variability despite their young age. |
| PubMed:Effect of repeated administration with subtoxic doses of acetaminophen to rats on enterohepatic recirculation of a subsequent toxic dose. |
| PubMed:Additional evidence that transaldolase exchange, isotope discrimination during the triose-isomerase reaction, or both occur in humans: effects of type 2 diabetes. |
| PubMed:Effect of the acute phase response induced by endotoxin administration on the expression and activity of UGT isoforms in rats. |
| PubMed:Altered disposition of acetaminophen in Nrf2-null and Keap1-knockdown mice. |
| PubMed:Simultaneous modelling of the Michaelis-Menten kinetics of paracetamol sulphation and glucuronidation. |
| PubMed:Sources of hepatic glucose production by 2H2O ingestion and Bayesian analysis of 2H glucuronide enrichment. |
| PubMed:Hepatic synthesis and urinary elimination of acetaminophen glucuronide are exacerbated in bile duct-ligated rats. |
| PubMed:Development of an HPLC-MS/MS method for the selective determination of paracetamol metabolites in mouse urine. |
| PubMed:Evidence that processes other than gluconeogenesis may influence the ratio of deuterium on the fifth and third carbons of glucose: implications for the use of 2H2O to measure gluconeogenesis in humans. |
| PubMed:Monitoring paracetamol metabolism after single and repeated administration in pediatric patients with neoplastic diseases. |
| PubMed:Beneficial effect of spironolactone administration on ethynylestradiol-induced cholestasis in the rat: involvement of up-regulation of multidrug resistance-associated protein 2. |
| PubMed:Urinary metabolites to assess in vivo ontogeny of hepatic drug metabolism in early neonatal life. |
| PubMed:Evidence for function of UDP galactose pyrophosphorylase in mice with absent galactose-1-phosphate uridyltransferase. |
| PubMed:Effects of combined UDP-glucuronosyltransferase (UGT) 1A1*28 and 1A6*2 on paracetamol pharmacokinetics in beta-thalassemia/HbE. |
| PubMed:Glucuronidation in the chimpanzee (Pan troglodytes): studies with acetaminophen, oestradiol and morphine. |
| PubMed:Evaluation of the role of multidrug resistance-associated protein (Mrp) 3 and Mrp4 in hepatic basolateral excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in Abcc3-/- and Abcc4-/- mice. |
| PubMed:Noninvasive analysis of hepatic glycogen kinetics before and after breakfast with deuterated water and acetaminophen. |
| PubMed:Identification of phenacetin metabolites in human urine after administration of phenacetin-C2H3: measurement of futile metabolic deacetylation via HPLC/MS-SPE-NMR and HPLC-ToF MS. |
| PubMed:A pharmacokinetic study of paracetamol in Thai beta-thalassemia/HbE patients. |
| PubMed:Multidrug resistance-associated proteins 3, 4, and 5. |
| PubMed:Ethynylestradiol increases expression and activity of rat liver MRP3. |
| PubMed:Contrasting changes in phase I and phase II metabolism of acetaminophen in male mice pretreated with carbon tetrachloride. |
| PubMed:Comments on "shift from biliary to urinary elimination of acetaminophen-glucuronide in acetaminophen-pretreated rats". |
| PubMed:Intra- and interindividual variability of glucuronidation of paracetamol during repeated administration of propacetamol in neonates. |
| PubMed:Pathways of galactose metabolism by galactosemics: evidence for galactose conversion to hepatic UDPglucose. |
| PubMed:Shift from biliary to urinary elimination of acetaminophen-glucuronide in acetaminophen-pretreated rats. |
| PubMed:Effect of taurine on biliary excretion and metabolism of acetaminophen in male hamsters. |
| PubMed:Glucuronidation of acetaminophen is independent of UGT1A1 promotor genotype. |
| PubMed:The quantification of paracetamol, paracetamol glucuronide and paracetamol sulphate in plasma and urine using a single high-performance liquid chromatography assay. |
| PubMed:Glucose production pathways by 2H and 13C NMR in patients with HIV-associated lipoatrophy. |
| PubMed:Higher insulin concentrations are required to suppress gluconeogenesis than glycogenolysis in nondiabetic humans. |
| PubMed:Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites. |
| PubMed:Feasibility of atmospheric pressure desorption/ionization on silicon mass spectrometry in analysis of drugs. |
| PubMed:Transiently altered acetaminophen metabolism after liver transplantation. |
| PubMed:Paracetamol and metabolite pharmacokinetics in infants. |
| PubMed:Hepatobiliary excretion of acetaminophen glutathione conjugate and its derivatives in transport-deficient (TR-) hyperbilirubinemic rats. |
| PubMed:Noninvasive evaluation of liver metabolism by 2H and 13C NMR isotopomer analysis of human urine. |
| PubMed:Analysis of acetaminophen glucuronide conjugate accompanied by adduct ion production by liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry. |
| PubMed:Mechanisms of impaired biliary excretion of acetaminophen glucuronide after acute phenobarbital treatment or phenobarbital pretreatment. |
| PubMed:Effect of enteral vs. parenteral glucose delivery on initial splanchnic glucose uptake in nondiabetic humans. |
| PubMed:Effect of nizatidine on paracetamol and its metabolites in human plasma. |
| PubMed:Acetaminophen and metabolite: lack of effect on nitric oxide synthase (constitutive or inducible). |
| PubMed:Disposition of acetaminophen and indocyanine green in cystic fibrosis-knockout mice. |
| PubMed:Interindividual variability in acetaminophen glucuronidation by human liver microsomes: identification of relevant acetaminophen UDP-glucuronosyltransferase isoforms. |
| PubMed:An integrated (2)H and (13)C NMR study of gluconeogenesis and TCA cycle flux in humans. |
| PubMed:Methods for measuring glycogen cycling. |
| PubMed:Cisapride raises the bioavailability of paracetamol by inhibiting its glucuronidation in man. |
| PubMed:Type I diabetes mellitus does not alter initial splanchnic glucose extraction or hepatic UDP-glucose flux during enteral glucose administration. |
| PubMed:Immune thrombocytopenia resulting from sensitivity to metabolites of naproxen and acetaminophen. |
| PubMed:High-performance liquid chromatographic assay for acetaminophen glucuronide in human liver microsomes. |
| PubMed:Tissue distribution and interindividual variation in human UDP-glucuronosyltransferase activity: relationship between UGT1A1 promoter genotype and variability in a liver bank. |
| PubMed:Lack of suppression of glucagon contributes to postprandial hyperglycemia in subjects with type 2 diabetes mellitus. |
| PubMed:Assessment of postprandial hepatic glycogen synthesis from uridine diphosphoglucose kinetics in obese and lean non-diabetic subjects. |
| PubMed:Altered hepatobiliary disposition of acetaminophen glucuronide in isolated perfused livers from multidrug resistance-associated protein 2-deficient TR(-) rats. |
| PubMed:Hepatic disposition of the acyl glucuronide 1-O-gemfibrozil-beta-D-glucuronide: effects of clofibric acid, acetaminophen, and acetaminophen glucuronide. |
| PubMed:Hepatic nonoxidative disposal of an oral glucose meal in patients with liver cirrhosis. |
| PubMed:Simple and rapid assay for acetaminophen and conjugated metabolites in low-volume serum samples. |
| PubMed:Sulphation deficit in "low-functioning" autistic children: a pilot study. |
| PubMed:Pharmacokinetics and metabolism of rectally administered paracetamol in preterm neonates. |
| PubMed:In vitro cleavage of paracetamol glucuronide by human liver and kidney beta-glucuronidase: determination of paracetamol by capillary electrophoresis. |
| PubMed:Role of CYP1A2 in the hepatotoxicity of acetaminophen: investigations using Cyp1a2 null mice. |
| PubMed:Blood sampling site-dependent plasma concentrations and hepatotoxic parameters in serum after intraperitoneal administration of acetaminophen to rats. |
| PubMed:Coadministration of acetaminophen and troglitazone: pharmacokinetics and safety. |
| PubMed:Metabolic changes of acetaminophen after intravenous administration to rats pretreated with 2-(allylthio)pyrazine. |
| PubMed:Monitoring in situ liver metabolism in rats using microdialysis. Comparison of microdialysis mass-transport model predictions to experimental metabolite generation data. |
| PubMed:NMR spectroscopic studies on the metabolism and futile deacetylation of phenacetin in the rat. |
| PubMed:In vitro mechanisms of probenecid-associated alterations in acetaminophen glucuronide hepatic disposition. |
| PubMed:Combined HPLC, NMR spectroscopy, and ion-trap mass spectrometry with application to the detection and characterization of xenobiotic and endogenous metabolites in human urine. |
| PubMed:Decrease of plasma and urinary oxidative metabolites of acetaminophen after consumption of watercress by human volunteers. |
| PubMed:Acetaminophen glucuronidation accurately reflects gluconeogenesis in fasted dogs. |
| PubMed:Effect of lipid-free total parenteral nutrition on hepatic drug conjugation in rats. |
| PubMed:Hepatic glycogen accurately reflected by acetaminophen glucuronide in dogs refed after fasting. |
| PubMed:Gluconeogenesis and glucuronidation in liver in vivo and the heterogeneity of hepatocyte function. |
| PubMed:A limitation in the use of mass isotopomer distributions to measure gluconeogenesis in fasting humans. |
| PubMed:Sulfation and glucuronidation of acetaminophen by human hepatocytes cultured on Matrigel and type 1 collagen reproduces conjugation in vivo. |
| PubMed:The adverse influence of pregnancy upon sulphation: a clue to the pathogenesis of intrahepatic cholestasis of pregnancy? |
| PubMed:The estimation of paracetamol and its major metabolites in both plasma and urine by a single high-performance liquid chromatography assay. |
| PubMed:Influence of rifampicin on the toxicity and the analgesic effect of acetaminophen. |
| PubMed:The effect of garlic extract on human metabolism of acetaminophen. |
| PubMed:Acute phenobarbital administration alters the disposition of acetaminophen metabolites in the rat. |
| PubMed:Hepatic disposition of acetaminophen and metabolites. Pharmacokinetic modeling, protein binding and subcellular distribution. |
| PubMed:Effect of genetic obesity and phenobarbital treatment on the hepatic conjugation pathways. |
| PubMed:Effect of phenobarbital and p-hydroxyphenobarbital glucuronide on acetaminophen metabolites in isolated rat hepatocytes: use of a kinetic model to examine the rates of formation and egress. |
| PubMed:Inhibition of acetaminophen and lorazepam glucuronidation in vitro by probenecid. |
| PubMed:The misuse of urinary metabolite excretion data in drug metabolism studies. |
| PubMed:The disposition of paracetamol and its conjugates during multiple dosing in patients with end-stage renal failure maintained on haemodialysis. |
| PubMed:Biotransformation and toxicity of acetaminophen in congenic RHA rats with or without a hereditary deficiency in bilirubin UDP-glucuronosyltransferase. |
| PubMed:p-aminophenol nephrotoxicity: biosynthesis of toxic glutathione conjugates. |
| PubMed:Probenecid-impaired biliary excretion of acetaminophen glucuronide and sulfate in the rat. |
| PubMed:Impaired biliary excretion of acetaminophen glucuronide in the isolated perfused rat liver after acute phenobarbital treatment and in vivo phenobarbital pretreatment. |
| PubMed:Protective effects of fulvotomentosides on acetaminophen-induced hepatotoxicity. |
| PubMed:Plasma concentration of paracetamol and its major metabolites after p.o. dosing with paracetamol or concurrent administration of paracetamol and its N-acetyl-DL-methionine ester in mice. |
| PubMed:Decreased glucuronidation and increased bioactivation of acetaminophen in Gilbert's syndrome. |
| PubMed:Variability of acetaminophen metabolism in Caucasians and Orientals. |
| PubMed:Changes in conjugative enzyme activity and acetaminophen metabolism in young and senescent male F-344 rats following prolonged exposure to buthionine sulfoximine. |
| PubMed:Disposition of drugs in cystic fibrosis. III. Acetaminophen. |
| PubMed:Gastric emptying in the postpartum period. |
| PubMed:Effects of protein and carbohydrate content of diet on drug conjugation. |
| PubMed:Protective effect of pregnenolone-16 alpha-carbonitrile on acetaminophen-induced hepatotoxicity in hamsters. |
| PubMed:The effect of malaria infection on paracetamol disposition in the rat. |
| PubMed:Oltipraz-induced amelioration of acetaminophen hepatotoxicity in hamsters. II. Competitive shunt in metabolism via glucuronidation. |
| PubMed:In vivo microdialysis sampling for pharmacokinetic investigations. |
| PubMed:Age-dependent changes in first-pass metabolism of acetaminophen in rats. |
| PubMed:Fish oil protects mice against acetaminophen hepatotoxicity in vivo. |
| PubMed:Drug metabolizing enzyme changes after chronic buthionine sulfoximine exposure modify acetaminophen disposition in rats. |
| PubMed:Phenacetin and acetaminophen metabolism in the isolated perfused rat liver. Precursor concentration influences the selection of kinetic parameters to assess hypoxic impairment. |
| PubMed:Noninvasive determination of acetaminophen disposition in Down's syndrome. |
| PubMed:Quantitative comparison of pathways of hepatic glycogen repletion in fed and fasted humans. |
| PubMed:Sulfation and glucuronidation of acetaminophen by cultured hepatocytes replicating in vivo metabolism. |
| PubMed:Isolation, identification, and analysis of 4-acetylaminophenol-glucuronide in body fluids of dialyzed renal patients; a molecular mass marker for peritoneal diffusive transport. |
| PubMed:First-pass metabolism of acetaminophen in rats after low and high doses. |
| PubMed:Altered hepatobiliary disposition of acetaminophen metabolites after phenobarbital pretreatment and renal ligation: evidence for impaired biliary excretion and a diffusional barrier. |
| PubMed:Dose-dependent intestinal glucuronidation and sulfation of acetaminophen in the rat in situ. |
| PubMed:Effect of microsomal enzyme inducers on biliary and urinary excretion of acetaminophen metabolites in rats. Decreased hepatobiliary and increased hepatovascular transport of acetaminophen-glucuronide after microsomal enzyme induction. |
| PubMed:Effect of amiodarone on the disposition of acetaminophen in the rat. |
| PubMed:Enhanced acetaminophen toxicity in rats with bilirubin glucuronyl transferase deficiency. |
| PubMed:Gastrointestinal, liver, and lung extraction ratio of acetaminophen in the rat after high dose administration. |
| PubMed:Disposition of phenacetin in rabbits pretreated orally and intraperitoneally with 3,4-benzpyrene. |
| PubMed:Influence of phenacetin and its metabolites on renal function. |
| PubMed:Estimation of phenolic conjugation by colonic mucosa. |
| PubMed:Transport of acetaminophen conjugates in isolated rat hepatocytes. |
| PubMed:Intestinal first-pass metabolism of phenacetin in rabbits pretreated orally and intraperitoneally with 3,4-benzpyrene. |
| PubMed:Paracetamol disposition and metabolite kinetics in patients with chronic renal failure. |
| PubMed:Acetaminophen metabolism in vivo by pregnant, fetal, and neonatal guinea pigs. |
| PubMed:Suppression of acetaminophen conjugation and of conjugate elimination in the rat by metyrapone, a classical P-450 inhibitor. |
| PubMed:Mechanism of decreased acetaminophen glucuronidation in the fasted rat. |
| PubMed:Effect of taurolithocholate on in vivo sulfation and glucuronidation of acetaminophen in rats. |
| PubMed:Effect of antipyrine coadministration on the kinetics of acetaminophen and lidocaine. |
| PubMed:A method for the preparation of calibration curves for acetaminophen glucuronide and acetaminophen sulfate in rabbit urine without use of authentic compounds in high-performance liquid chromatography. |
| PubMed:Glycoconjugates as noninvasive probes of intrahepatic metabolism: II. Application to measurement of plasma alpha 1-acid glycoprotein turnover during inflammation. |
| PubMed:Glycoconjugates as noninvasive probes of intrahepatic metabolism: I. Kinetics of label incorporation with evidence of a common precursor UDP-glucose pool for secreted glycoconjugates. |
| PubMed:Paracetamol conjugation: an interethnic and dietary study. |
| PubMed:BHA (2(3)-tert-butyl-4-hydroxyanisole)-mediated modulation of acetaminophen phase II metabolism in vivo in Fisher 344 rats. |
| PubMed:Acetaminophen sulfation deficit in obese rats overfed an energy-dense cafeteria diet. |
| PubMed:Pharmacokinetic consequences and toxicologic implications of metyrapone-induced alterations of acetaminophen elimination in man. |
| PubMed:Biochemical changes associated with the potentiation of acetaminophen hepatotoxicity by brief anesthesia with diethyl ether. |
| PubMed:An overfed rat model that reproduces acetaminophen disposition in obese humans. |
| PubMed:Effect of prevention of inorganic sulfate depletion on the pharmacokinetics of acetaminophen in rats. |
| PubMed:Effect of reduced hepatic energy state on acetaminophen conjugation in rats. |
| PubMed:Pharmacokinetic studies of the disposition of acetaminophen in the sheep maternal-placental-fetal unit. |
| PubMed:Hepatic UDP-glucuronic acid regulation during acetaminophen biotransformation in rats. |
| PubMed:Toxicological studies in a Distalgesic addict. |
| PubMed:Effects of butylated hydroxyanisole on acetaminophen hepatotoxicity and glucuronidation in vivo. |
| PubMed:Renal transport of the glucuronides of paracetamol and p-nitrophenol in the dog. |
| PubMed:Effects of cysteine pro-drugs on acetaminophen-induced hepatotoxicity. |
| PubMed:Effect of aging on drug-metabolizing enzymes important in acetaminophen elimination. |
| PubMed:Anomalous susceptibility of the fasted hamster to acetaminophen hepatotoxicity. |
| PubMed:Comparison of the effects of sodium sulfate and N-acetylcysteine on the hepatotoxicity of acetaminophen in mice. |
| PubMed:Influence of advanced age on the formation and elimination of acetaminophen metabolites by male rats. |
| PubMed:Absorption and metabolism of acetaminophen by the in situ perfused rat small intestine preparation. |
| PubMed:Distribution and fate of acetaminophen conjugates in fetal lambs in utero. |
| PubMed:Probenecid impairment of acetaminophen and lorazepam clearance: direct inhibition of ether glucuronide formation. |
| PubMed:A high resolution proton nuclear magnetic resonance approach to the study of hepatocyte and drug metabolism. Application to acetaminophen. |
| PubMed:Micro high-performance liquid chromatographic assay of acetaminophen and its major metabolites in plasma and urine. |
| PubMed:Studies on the fate of the glutathione and cysteine conjugates of acetaminophen in mice. |
| PubMed:Disposition of acetaminophen in protein-calorie malnutrition. |
| PubMed:Pharmacokinetic study of the enterohepatic circulation of acetaminophen glucuronide in rats. |
| PubMed:Sources of interindividual variations in acetaminophen and antipyrine metabolism. |
| PubMed:Renal clearance and serum protein binding of acetaminophen and its major conjugates in humans. |
| PubMed:Glucuronidation and biliary excretion of acetaminophen in rats. |
| PubMed:Effect of brussels sprouts and cabbage on drug conjugation. |
| PubMed:Biliary excretion of acetaminophen in ureter-ligated rats. |
| PubMed:Acetaminophen metabolism in subjects fed charcoal-broiled beef. |
| PubMed:Mechanism of ketone-induced protection from acetaminophen hepatotoxicity in the rat. |
| PubMed:Pharmacokinetic study of the fate of acetaminophen and its conjugates in rats. |
| PubMed:Intracellular inhibition of UDP-glucose dehydrogenase during ethanol oxidation. |
| PubMed:Platelet phenol sulfotransferase activity: correlation with sulfate conjugation of acetaminophen. |
| PubMed:Effect of experimental renal failure on sulfate retention and acetaminophen pharmacokinetics in rats. |
| PubMed:Altered acetaminophen disposition in fed and food-deprived rats after acute ethanol administration. |
| PubMed:Acetaminophen pharmacokinetics after overdose. |
| PubMed:High-performance liquid chromatographic assay for acetaminophen and phenacetin in the presence of their metabolites in biological fluids. |
| PubMed:Effect of subacute dosing and phenobarbital and 3-methylcholanthrene pretreatment on the metabolism of acetaminophen in rats. |
| PubMed:Drug biotransformation interactions in man VI: acetaminophen and ascorbic acid. |
| PubMed:Pharmacokinetics of acetaminophen elimination by anephric patients. |
| PubMed:Effect of hemodialysis on kinetics of acetaminophen elimination by anephric patients. |
| PubMed:Pharmacokinetics of acetaminophen in the human neonate: formation of acetaminophen glucuronide and sulfate in relation to plasma bilirubin concentration and D-glucaric acid excretion. |
3D/inchi