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Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | water, 1.185e+005 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for D-1,5-anhydrofructose usage levels up to: | | | not for fragrance use.
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| Recommendation for D-1,5-anhydrofructose flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 1,5- | anhydro-D-fructose | | (4S,5S,6R)-4,5- | dihydroxy-6-(hydroxymethyl)oxan-3-one | | D- | fructose, 1:5-anhydro- |
Articles:
| PubMed:Production of 1,5-anhydro-d-fructose by an α-glucosidase belonging to glycoside hydrolase family 31. |
| PubMed:The structure of substrate-free 1,5-anhydro-D-fructose reductase from Sinorhizobium meliloti 1021 reveals an open enzyme conformation. |
| PubMed:Crystal structure of α-1,4-glucan lyase, a unique glycoside hydrolase family member with a novel catalytic mechanism. |
| PubMed:Effect of 1,5-anhydro-D-fructose on the inhibition of adipogenesis in 3T3-L1 adipocytes. |
| PubMed:Two structures of a thiazolinyl imine reductase from Yersinia enterocolitica provide insight into catalysis and binding to the nonribosomal peptide synthetase module of HMWP1. |
| PubMed:Lyase activity of glycogen synthase: Is an elimination/addition mechanism a possible reaction pathway for retaining glycosyltransferases? |
| PubMed:1,5-Anhydro-D-fructose: A natural antibiotic that inhibits the growth of gram-positive bacteria and microbial biofilm formation to prevent nosocomial infection. |
| PubMed:Study on administration of 1,5-anhydro-D-fructose in C57BL/6J mice challenged with high-fat diet. |
| PubMed:1,5-anhydro-D-fructose and its derivatives: biosynthesis, preparation and potential medical applications. |
| PubMed:1,5-Anhydro-D-fructose: biocatalytic and chemical synthetic methods for the preparation, transformation and derivatization. |
| PubMed:Attenuation of LPS-induced iNOS expression by 1,5-anhydro-d-fructose. |
| PubMed:Synthesis of 4-O-glycosylated 1,5-anhydro-D-fructose and of 1,5-anhydro-D-tagatose from a common intermediate 2,3-O-isopropylidene-D-fructose. |
| PubMed:Inhibition spectrum studies of microthecin and other anhydrofructose derivatives using selected strains of Gram-positive and -negative bacteria, yeasts and moulds, and investigation of the cytotoxicity of microthecin to malignant blood cell lines. |
| PubMed:1,5-Anhydro-D-fructose attenuates lipopolysaccharide-induced cytokine release via suppression of NF-kappaB p65 phosphorylation. |
| PubMed:The anhydrofructose pathway of glycogen catabolism. |
| PubMed:Structure of monkey dimeric dihydrodiol dehydrogenase in complex with isoascorbic acid. |
| PubMed:Mouse AKR1E1 is an ortholog of pig liver NADPH dependent 1,5-anhydro-D-fructose reductase. |
| PubMed:1,5-anhydro-D-fructose from D-fructose. |
| PubMed:Crystal structure of NADP(H)-dependent 1,5-anhydro-D-fructose reductase from Sinorhizobium morelense at 2.2 A resolution: construction of a NADH-accepting mutant and its application in rare sugar synthesis. |
| PubMed:A cold active (2R,3R)-(-)-di-O-benzoyl-tartrate hydrolyzing esterase from Rhodotorula mucilaginosa. |
| PubMed:A new chemical synthesis of Ascopyrone P from 1,5-anhydro-D-fructose. |
| PubMed:Synthesis of 1,4-anhydro-D-fructose and 1,4-anhydro-D-tagatose. |
| PubMed:Catabolism of 1,5-anhydro-D-fructose in Sinorhizobium morelense S-30.7.5: discovery, characterization, and overexpression of a new 1,5-anhydro-D-fructose reductase and its application in sugar analysis and rare sugar synthesis. |
| PubMed:Examination of 1,5-anhydro-D-fructose and the enolone ascopyrone P, metabolites of the anhydrofructose pathway of glycogen and starch degradation, for their possible application in fruits, vegetables, and beverages as antibrowning agents. |
| PubMed:A 90-day toxicological evaluation of 1,5-anhydro-d-fructose in Sprague-Dawley rats. |
| PubMed:Enzymatic description of the anhydrofructose pathway of glycogen degradation II. Gene identification and characterization of the reactions catalyzed by aldos-2-ulose dehydratase that converts 1,5-anhydro-D-fructose to microthecin with ascopyrone M as the intermediate. |
| PubMed:A novel family of glucosyl 1,5-anhydro-d-fructose derivatives synthesised by transglucosylation with dextransucrase from Leuconostoc mesenteroides NRRL B-512F. |
| PubMed:Basic toxicology and metabolism studies of 1,5-anhydro-D-fructose using bacteria, cultured mammalian cells, and rodents. |
| PubMed:Synthesis and co-polymerization of an unsaturated 1,5-anhydro-D-fructose derivative. |
| PubMed:Enzymatic description of the anhydrofructose pathway of glycogen degradation; I. Identification and purification of anhydrofructose dehydratase, ascopyrone tautomerase and alpha-1,4-glucan lyase in the fungus Anthracobia melaloma. |
| PubMed:Preparation and reactivity of a novel disaccharide, glucosyl 1,5-anhydro-D-fructose (1,5-anhydro-3-O-alpha-glucopyranosyl-D-fructose). |
| PubMed:1,5-Anhydro-D-fructose; a versatile chiral building block: biochemistry and chemistry. |
| PubMed:Antioxidant effects of 1,5-anhydro-D-fructose, a new natural sugar, in vitro. |
| PubMed:1,5-Anhydro-D-fructose increases glucose tolerance by increasing glucagon-like peptide-1 and insulin in mice. |
| PubMed:alpha-1,4-glucan lyases producing 1,5-anhydro-D-fructose from starch and glycogen have sequence similarity to alpha-glucosidases. |
| PubMed:A group of alpha-1,4-glucan lyase genes from the fungi Morchella costata, M. vulgaris and Peziza ostracoderma. Cloning, complete sequencing and heterologous expression. |
| PubMed:A group of alpha-1,4-glucan lyases and their genes from the red alga Gracilariopsis lemaneiformis: purification, cloning, and heterologous expression. |
| PubMed:Analysis of 1,5-anhydro-D-fructose, microthecin, and 4-deoxy-glycero-hexo-2,3-diulose in algae using gas chromatography-mass spectrometry in selected ion monitoring mode. |
| PubMed:Purification and some properties of a hepatic NADPH-dependent reductase that specifically acts on 1,5-anhydro-D-fructose. |
| PubMed:Efficient purification, characterization and partial amino acid sequencing of two alpha-1,4-glucan lyases from fungi. |
| PubMed:NMR of all-carbon-13 sugars: an application in development of an analytical method for a novel natural sugar, 1,5-anhydrofructose. |
| PubMed:alpha-1,4-Glucan lyase, a new class of starch/glycogen degrading enzyme. III. Substrate specificity, mode of action, and cleavage mechanism. |
| PubMed:Effects of 1,5-anhydro-D-fructose on selected glucose-metabolizing enzymes. |
| PubMed:Oxidation of 1,5-anhydro-D-glucitol to 1,5-anhydro-D-fructose catalyzed by an enzyme from bacterial membranes. |
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3D/inchi