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Isoacteoside

Supplier Sponsors

CAS Number: 61303-13-7Picture of molecule3D/inchi
FDA UNII: 588LJK42AP
MDL:MFCD06798947
Molecular Weight:624.59392000
Formula:C29 H36 O15
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 2281 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Isoacteoside 98%
BOC Sciences
For experimental / research use only.
Isoacteoside >98%
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for Isoacteoside usage levels up to:
 not for fragrance use.
 
Recommendation for Isoacteoside flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :6476333
National Institute of Allergy and Infectious Diseases:Data
[(2R,3R,4S,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-3,5-dihydroxy-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]methyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
Chemidplus:0061303137
 
References:
  [(2R,3R,4S,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-3,5-dihydroxy-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]methyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):6476333
Pubchem (cas):61303-13-7
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):HMDB41025
FooDB:FDB020894
VCF-Online:VCF Volatile Compounds in Food
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 lippia alba
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 lippia canescens
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 lippia dulcis
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 magnolia denudata flower
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 paulownia tomentosa
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Synonyms:
[(2R,3R,4S,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-3,5-dihydroxy-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]methyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
beta-D-glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-alpha-L-mannopyranosyl)-, 6-(3-(3,4-dihydroxyphenyl)-2-propenoate), (E)-
 

Articles:

PubMed:Isoacteoside, a dihydroxyphenylethyl glycoside, exhibits anti-inflammatory effects through blocking toll-like receptor 4 dimerization
PubMed:Acteoside and Isoacteoside Protect Amyloid ? Peptide Induced Cytotoxicity, Cognitive Deficit and Neurochemical Disturbances In Vitro and In Vivo
PubMed:Anti-inflammatory effects of isoacteoside from Abeliophyllum distichum
PubMed:Suppression of in vitro and in vivo human ovarian cancer growth by isoacteoside is mediated via sub-G1 cell cycle arrest, ROS generation, and modulation of AKT/PI3K/m-TOR signalling pathway
PubMed:Simultaneous determination of savaside A, acteoside, and isoacteoside in rat plasma by UHPLC-MS/MS: Comparative pharmacokinetic and bioavailability characteristics of Monochasma savatieri via different routes of administra
PubMed:A metabolic way to investigate related hurdles causing poor bioavailability in oral delivery of isoacteoside in rats employing ultrahigh-performance liquid chromatography/quadrupole time-of-flight tandem mass spectrometry
PubMed:Isolation and purification of acteoside and isoacteoside from Plantago psyllium L. by high-speed counter-current chromatography
PubMed:Antioxidant activity of isoacteoside from Clerodendron trichotomum
PubMed:Inhibitory activities of acteoside, isoacteoside, and its structural constituents against protein glycation in vitro
PubMed:Antioxidant activity of phenylethanoid glycosides on glutamate-induced neurotoxicity
PubMed:Medicinal plants with concomitant anti-diabetic and anti-hypertensive effects as potential sources of dual acting therapies against diabetes and hypertension: A review
PubMed:Two-phase hollow fiber liquid phase microextraction based on magnetofluid for simultaneous determination of Echinacoside, Tubuloside B, Acteoside and Isoacteoside in rat plasma after oral administration of Cistanche salsa
PubMed:Acteoside and Acyl-Migrated Acteoside, Compounds in Chinese Kudingcha Tea, Inhibit -Amylase In Vitro
PubMed:Enzyme inhibitory assessment of the isolated constituents from Plantago holosteum Scop
PubMed:A new macrocyclic diterpenoid from Anisomeles indica
PubMed:Isoacteoside attenuates acute kidney injury induced by severe acute pancreatitis
PubMed:UPLC-QTOF-MS/MS screening and identification of bioactive compounds in fresh, aged, and browned Magnolia denudata flower extracts
PubMed:Computational Determination of Potential Inhibitors of SARS-CoV-2 Main Protease
PubMed:[Chemome profiling and comparison of three Orobanche medicinal plants]
PubMed:Antineoplastic agents, 107. Isolation of acteoside and isoacteoside from Castilleja linariaefolia
PubMed:Screening and identification of three typical phenylethanoid glycosides metabolites from Cistanches Herba by human intestinal bacteria using UPLC/Q-TOF-MS
PubMed:Active compounds isolated from Plantago subulata L. via wound healing and antiinflammatory activity guided studies
PubMed:Cistanches Herba: An overview of its chemistry, pharmacology, and pharmacokinetics property
PubMed:Quality Assessment of Commercial Spagyric Tinctures of Harpagophytum procumbens and Their Antioxidant Properties
PubMed:[Comparative studies of three Cistanche speices based on UPLC specific chromatogram and determination of main components]
PubMed:Antioxidative activities of phenylethanoid glycosides from Ligustrum purpurascens
PubMed:Bioactivity, Compounds Isolated, Chemical Qualitative, and Quantitative Analysis of Cymbaria daurica Extracts
PubMed:Fixed oil from seeds of narrow-leaved ash (F. angustifolia subsp. angustifolia): Chemical profile, antioxidant and antiproliferative activities
PubMed:Biosynthesis of acteoside in cultured cells of Olea europaea
PubMed:Antioxidant Activity, Enzyme Inhibition Potentials, and Phytochemical Profiling of Premna serratifolia L. Leaf Extracts
PubMed:The Difference of Chemical Components and Biological Activities of the Raw Products slices and the Wine Steam-Processed Product from Cistanche deserticola
PubMed:Simultaneous Quantification of Four Phenylethanoid Glycosides in Rat Plasma by UPLC-MS/MS and Its Application to a Pharmacokinetic Study of Acanthus Ilicifolius Herb
PubMed:Antiproliferative constituents in the plants 7. Leaves of Clerodendron bungei and leaves and bark of C. trichotomum
PubMed:Extract of Plantago asiatica L. Seeds Ameliorates Hypertension in Spontaneously Hypertensive Rats by Inhibition of Angiotensin Converting Enzyme
PubMed:Acylated phenylethanoid oligoglycosides with hepatoprotective activity from the desert plant Cistanche tubulosa
PubMed:The influence of light quality on the production of bioactive metabolites - verbascoside, isoverbascoside and phenolic acids and the content of photosynthetic pigments in biomass of Verbena officinalis L. cultured in vitro
PubMed:In-silico prediction of potential inhibitors against phosphatidylinositol 3-kinase catalytic subunit alpha involved in head and neck squamous cell carcinomas
PubMed:Simultaneous quantification of five bioactive phenylethanoid, iridoid, and flavonol glycosides in Duranta erecta L.: Ultra performance liquid chromatography method validation and uncertainty measurement
PubMed:Production of Verbascoside, Isoverbascoside and Phenolic Acids in Callus, Suspension, and Bioreactor Cultures of Verbena officinalis and Biological Properties of Biomass Extracts
PubMed:Xanthine oxidase inhibitors from Brandisia hancei
PubMed:Effect of phenylethanoid glycosides and polysaccharides from the seed of Plantago asiatica L. on the maturation of murine bone marrow-derived dendritic cells
PubMed:Caffeoylated phenylpropanoid glycosides from Brandisia hancei inhibit advanced glycation end product formation and aldose reductase in vitro and vessel dilation in larval zebrafish in vivo
PubMed:Simultaneous quantification of six phenylethanoid glycosides in some Turkish Scutellaria species by a new HPLC-DAD method
PubMed:Neuroprotective Effects of Four Phenylethanoid Glycosides on H?O?-Induced Apoptosis on PC12 Cells via the Nrf2/ARE Pathway
PubMed:Phenylpropanoids from the stem bark of Jacaranda mimosaefolia
PubMed:Phenylethanoid and flavone glycosides from Ruellia tuberosa L
PubMed:Seasonal variation in the chemical composition of two chemotypes of Lippia alba
PubMed:Cholinesterase inhibitors from the roots of Harpagophytum procumbens
PubMed:Antigout Effects of Plantago asiatica: Xanthine Oxidase Inhibitory Activities Assessed by Electrochemical Biosensing Method
PubMed:Phenylpropanoid glycosides from Orobanche caerulescens
PubMed:On-line HPLC-DPPH bioactivity-guided assay for isolated of antioxidative phenylpropanoids from Qinghai-Tibet Plateau medicinal plant Lancea tibetica
PubMed:Iridoid glycosides from Globularia davisiana
PubMed:Plant-derived verbascoside and isoverbascoside regulate Toll-like receptor 2 and 4-driven neutrophils priming and activation
PubMed:Antioxidant principles from Bauhinia tarapotensis
PubMed:Iridoid, phenylethanoid and flavonoid glycosides from Sideritis trojana
PubMed:Layer-by-layer assembly strategy for fabrication of polydopamine-polyethyleneimine hybrid modified fibers and their application to solid-phase microextraction of bioactive molecules from medicinal plant samples followed by
PubMed:Separation of phenylpropanoid glycosides from a Chinese herb by HSCCC
PubMed:Iridoid glycosides from Globularia trichosantha
PubMed:Chemical characterization and biological activity in young sesame leaves (Sesamum indicum L.) and changes in iridoid and polyphenol content at different growth stages
PubMed:A Novel HPLC Method for Direct Detection of Nitric Oxide Scavengers from Complex Plant Matrices and Its Application to Aloysia triphylla Leaves
PubMed:Anti-inflammatory phenylpropanoid glycosides from Clerodendron trichotomum leaves
PubMed:Degradation of phenylethanoid glycosides in Osmanthus fragrans Lour. flowers and its effect on anti-hypoxia activity
PubMed:[Caffeoyl phenylethanoid glycosides from Callicarpa kwangtungensis]
PubMed:Antiproliferative constituents in plants 9. Aerial parts of Lippia dulcis and Lippia canescens
PubMed:Phenylethanoid Glycoside Profiles and Antioxidant Activities of Osmanthus fragrans Lour. Flowers by UPLC/PDA/MS and Simulated Digestion Model
PubMed:Amphipaniculosides A-D, triterpenoid glycosides, and amphipaniculoside E, an aliphatic alcohol glycoside from the leaves of Amphilophium paniculatum
PubMed:Antihepatotoxic activity and chemical constituents of Buddleja asiatica Lour
PubMed:Phenylpropanoid glycosides from the leaves of Paulownia coreana
PubMed:Pro-oxidative action of polyphenols as action mechanism for their pro-apoptotic activity
PubMed:[Chemical Constitutes from Seeds of Plantago asiatica]
PubMed:Phenylethanoid and iridoid glycosides from Veronica persica
PubMed:Alteration of Neutrophil Reactive Oxygen Species Production by Extracts of Devil's Claw (Harpagophytum)
PubMed:Rational quality assessment procedure for less-investigated herbal medicines: Case of a Congolese antimalarial drug with an analytical report
PubMed:Antiradical activity of Paulownia tomentosa (Scrophulariaceae) extracts
PubMed:Acylated phenylethanoid glycosides, echinacoside and acteoside from Cistanche tubulosa, improve glucose tolerance in mice
PubMed:Antioxidant phenylethanoid glycosides and a neolignan from Jacaranda caucana
PubMed:Evaluation of anticandidal and antioxidant activities of phenolic compounds from Pyrostegia venusta (Ker Gawl.) Miers
PubMed:The Osmanthus fragrans flower phenylethanoid glycoside-rich extract: Acute and subchronic toxicity studies
PubMed:Convenient TLC-based Identification Test for the Crude Drug "Pogostemoni Herba"
PubMed:Identification of bioactive ingredients with immuno-enhancement and anti-oxidative effects from Fufang-Ejiao-Syrup by LC-MS(n) combined with bioassays
PubMed:Analysis of the inhibitory activity of Abeliophyllum distichum leaf constituents against aldose reductase by using high-speed counter current chromatography
PubMed:Three new flavonoid glycosides, byzantionoside B 6'-O-sulfate and xyloglucoside of (Z)-hex-3-en-1-ol from Ruellia patula
PubMed:Identification of major metal complexing compounds in Blepharis aspera
PubMed:Preparative isolation and purification of four compounds from Cistanches deserticola Y.C. Ma by high-speed counter-current chromatography
PubMed:The antioxidant activity and thermal stability of lemon verbena (Aloysia triphylla) infusion
PubMed:Diterpenoids and phenylethanoid glycosides from the roots of Clerodendrum bungei and their inhibitory effects against angiotensin converting enzyme and -glucosidase
PubMed:Verbascoside, isoverbascoside, and their derivatives recovered from olive mill wastewater as possible food antioxidants
PubMed:Bioguided isolation of angiotensin-converting enzyme inhibitors from the seeds of Plantago asiatica L
PubMed:[Isolation and characterization of phenylethanoid glycosides from Clerodendron bungei]
PubMed:[Effects of phenylethanoid glycosides from seeds of Plantago asiatica on maturation of dendritic cells]
PubMed:Changes in Levels of Phenylethanoid Glycosides, Antioxidant Activity, and Other Quality Traits in Cistanche deserticola Slices by Steam Processing
PubMed:New metabolites of acteoside identified by ultra-performance liquid chromatography/quadrupole-time-of-flight MS(E) in rat plasma, urine, and feces
PubMed:Hepatoprotective activity of phenylethanoids from Cistanche deserticola
PubMed:Phenylpropanoid and iridoid glycosides from Pedicularis striata
PubMed:Phenylpropanoid glycosides from Scrophularia scorodonia: in vitro anti-inflammatory activity
PubMed:Preparation and physicochemical characterization of Ag nanoparticles biosynthesized by Lippia citriodora (Lemon Verbena)
PubMed:UPLC-ESI-Q-TOF-MS-Based Metabolite Profiling, Antioxidant and Anti-Inflammatory Properties of Different Organ Extracts of Abeliophyllum distichum
PubMed:Immunosuppressive principles of Rehmannia glutinosa var. hueichingensis
PubMed:Induction of differentiation in human hepatocarcinoma cells by isoverbascoside
PubMed:In vitro neuroprotective activities of phenylethanoid glycosides from Callicarpa dichotoma
PubMed:Immunosuppressive Principles of Rehmannia glutinosa var. hueichingensis1
PubMed:Isolation and purification of phenylethanoid glycosides from Cistanche deserticola by high-speed counter-current chromatography
PubMed:[Chemical Constituents from Leaves of Acanthus ilicifolius and Their Anti-influenza Virus Activities]
PubMed:Antioxidative effects of phenylethanoids from Cistanche deserticola
PubMed:New Bisabolane-Type Sesquiterpenes from the Aerial Parts of Lippia dulcis
PubMed:Evaluation of the intestinal transport of a phenylethanoid glycoside-rich extract from Cistanche deserticola across the Caco-2 cell monolayer model
PubMed:Chemical constituents of Acanthus ilicifolius L. and effect on osteoblastic MC3T3E1 cells
PubMed:Antioxidant constituents of the aerial parts of Globularia alypum growing in Morocco
PubMed:Caffeic Acid Derivatives from Bacopa monniera Plants as Inhibitors of Pancreatic Lipase Activity and their Structural Requirements
PubMed:Antispasmodic activity of an extract from Plantago lanceolata L. and some isolated compounds
PubMed:[Identification of Chinese Traditional Medicine Cistanches Herba from Different Places by HPLC-ESI-MS and FTIR Methods]
PubMed:Four glycosides from the leaves of Abeliophyllum distichum with inhibitory effects on angiotensin converting enzyme
PubMed:Integrated Strategy Drives Direct Infusion-Tandem Mass Spectrometry as an Eligible Tool for Shotgun Pseudo-Targeted Metabolomics of Medicinal Plants
PubMed:Gastroprotection as an example: antiadhesion against Helicobacter pylori, anti-inflammatory and antioxidant activities of aqueous extracts from the aerial parts of Lippia integrifolia Hieron
PubMed:[Structure-activity relationships of phenylethanoid glycosides in plants of Cistanche salsa on antioxidative activity]
PubMed:Comparative analysis of three Callicarpa herbs using high performance liquid chromatography with diode array detector and electrospray ionization-trap mass spectrometry method
PubMed:Verbascosides from olive mill waste water: assessment of their bioaccessibility and intestinal uptake using an in vitro digestion/Caco-2 model system
PubMed:Inhibition of nitric oxide by phenylethanoids in activated macrophages
PubMed:Acteoside and 6-O-acetylacteoside downregulate cell adhesion molecules induced by IL-1beta through inhibition of ERK and JNK in human vascular endothelial cells
PubMed:[Isolation and identification of compounds from marine mangrove plant Avicennia marina]
PubMed:Antioxidative and chelating activities of phenylpropanoid glycosides from Pedicularis striata
PubMed:A comparative study of some Veronica species
PubMed:Isolation, structure elucidation and antioxidant potential of the major phenolic and flavonoid compounds in brined olive drupes
PubMed:Phenylethanoids in the herb of Plantago lanceolata and inhibitory effect on arachidonic acid-induced mouse ear edema
PubMed:Pedicularioside A from Buddleia lindleyana inhibits cell death induced by 1-methyl-4-phenylpyridinium ions (MPP+) in primary cultures of rat mesencephalic neurons
PubMed:Effect of isoverbascoside, a phenylpropanoid glycoside antioxidant, on proliferation and differentiation of human gastric cancer cell
PubMed:New and known iridoid- and phenylethanoid glycosides from Harpagophytum procumbens and their in vitro inhibition of human leukocyte elastase
PubMed:[Phenylethanoid glucosides from flos Buddlejae]
PubMed:Chemical constituents of the aerial parts of Scutellaria lateriflora and their alpha-glucosidase inhibitory activities
PubMed:Antioxidant and anti-cholinesterase activity of Globularia meridionalis extracts and isolated constituents
PubMed:A new rearranged abietane diterpene and other constituents from Clerodendrum philipinum
PubMed:[Analysis of phenylethanoid glycosides in the extract of herba Cistanchis by LC/ESI-MS/MS]
PubMed:Isolation, purification and structure identification of two phenolic glycosides from the roots of Incarvillea younghusbandii Sprague and their antioxidant activities
PubMed:Simultaneous separation and determination of four phenylethanoid glycosides in rat plasma sample after oral administration of Cistanche salsa extract by microemulsion liquid chromatography
PubMed:[Chemical constituents from rhizome of Phlomis umbrosa]
PubMed:Hypoglycemic and hypolipidemic effects of total glycosides of Cistanche tubulosa in diet/streptozotocin-induced diabetic rats
PubMed:[Study on chemical constituents of mangrove Acanthus ilcifolius]
PubMed:[Induced-differentiation and cytotoxicity of isoverbascoside on HL-60 cells]
PubMed:[Metabolic regulation of phenylethanoid glycosides from Herba cistanches in dogs' gastrointestine]
PubMed:Protection of phenylpropanoid glycosides from Pedicularis against oxidative hemolysis in vitro
PubMed:[Studies on the chemical constituents from herba of Corallodiscus flabellata]
 
Notes:
None found
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