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ginsenoside F1

Supplier Sponsors

CAS Number: 53963-43-2Picture of molecule3D/inchi
Other(deleted CASRN):156912-00-4
FDA UNII: Search
Nikkaji Web:J38.859I
MDL:MFCD06410947
XlogP3-AA:4.30 (est)
Molecular Weight:638.88294000
Formula:C36 H62 O9
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
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Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 0.07331 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Ginsenoside F1 98%
BOC Sciences
For experimental / research use only.
Ginsenoside F1
Carbosynth
For experimental / research use only.
Ginsenoside F1
Sigma-Aldrich: Sigma
For experimental / research use only.
Ginsenoside F1 ≥98% (HPLC)
sds
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for ginsenoside F1 usage levels up to:
 not for fragrance use.
 
Recommendation for ginsenoside F1 flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :9809542
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[(2S)-6-methyl-2-[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,6,12-trihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]hept-5-en-2-yl]oxyoxane-3,4,5-triol
Chemidplus:0053963432
 
References:
 (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[(2S)-6-methyl-2-[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,6,12-trihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]hept-5-en-2-yl]oxyoxane-3,4,5-triol
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):9809542
Pubchem (cas):53963-43-2
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C20780
HMDB (The Human Metabolome Database):HMDB39555
FooDB:FDB019176
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 panax ginseng
Search Trop Picture
 
Synonyms:
beta-D-glucopyranoside, (3beta,6aalpha,12beta)-3,6,12-trihydroxydammar-24-ene-20-yl
(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[(2S)-6-methyl-2-[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,6,12-trihydroxy-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]hept-5-en-2-yl]oxyoxane-3,4,5-triol
 

Articles:

PubMed:Ginsenoside F1 suppresses astrocytic senescence-associated secretory phenotype.
PubMed:Rare ginsenoside Ia synthesized from F1 by cloning and overexpression of the UDP-glycosyltransferase gene fromBacillus subtilis: synthesis, characterization, andin vitromelanogenesis inhibition activity in BL6B16 cells.
PubMed:Ginsenoside F1 Ameliorates Endothelial Cell Inflammatory Injury and Prevents Atherosclerosis in Mice through A20-Mediated Suppression of NF-kB Signaling.
PubMed:Metabolic analysis of Panax notoginseng saponins with gut microbiota-mediated biotransformation by HPLC-DAD-Q-TOF-MS/MS.
PubMed:Gram-Scale Production of Ginsenoside F1 Using a Recombinant Bacterial β-Glucosidase.
PubMed:Production of ginsenoside F1 using commercial enzyme Cellulase KN.
PubMed:Screening SIRT1 Activators from Medicinal Plants as Bioactive Compounds against Oxidative Damage in Mitochondrial Function.
PubMed:Characterization of Panax ginseng UDP-Glycosyltransferases Catalyzing Protopanaxatriol and Biosyntheses of Bioactive Ginsenosides F1 and Rh1 in Metabolically Engineered Yeasts.
PubMed:Ginsenoside F1 attenuates hyperpigmentation in B16F10 melanoma cells by inducing dendrite retraction and activating Rho signalling.
PubMed:Role of epidermal γδ T-cell-derived interleukin 13 in the skin-whitening effect of Ginsenoside F1.
PubMed:Inhibitory effects of herbal constituents on P-glycoprotein in vitro and in vivo: herb-drug interactions mediated via P-gp.
PubMed:Production of ginsenoside aglycons and Rb1 deglycosylation pathway profiling by HPLC and ESI-MS/MS using Sphingobacterium multivorum GIN723.
PubMed:Metabolite profiling of ginsenoside Re in rat urine and faeces after oral administration.
PubMed:Bioconversion of major ginsenosides Rg1 to minor ginsenoside F1 using novel recombinant ginsenoside hydrolyzing glycosidase cloned from Sanguibacter keddieii and enzyme characterization.
PubMed:Co-transformation of Panax major ginsenosides Rb₁ and Rg₁ to minor ginsenosides C-K and F₁ by Cladosporium cladosporioides.
PubMed:Microbial transformation of ginsenoside-Rg₁ by Absidia coerulea and the reversal activity of the metabolites towards multi-drug resistant tumor cells.
PubMed:Ginsenoside F1 production from ginsenoside Rg1 by a purified β-glucosidase from Fusarium moniliforme var. subglutinans.
PubMed:Purification and characterization of a novel and unique ginsenoside Rg1-hydrolyzing β-D-glucosidase from Penicillium sclerotiorum.
PubMed:[Pharmacokinetics of ginsenosides Rg1 and its metabolites in rats].
PubMed:Dammarane-type glycosides and long chain sesquiterpene glycosides from Gynostemma yixingense.
PubMed:[Metabolic study of ginsenoside Re in rats].
PubMed:Screening of anti-platelet aggregation agents from Panax notoginseng using human platelet extraction and HPLC-DAD-ESI-MS/MS.
PubMed:Influence of ginsenoside Rh1 and F1 on human cytochrome p450 enzymes.
PubMed:Metabolism of ginsenoside Re by human intestinal microflora and its estrogenic effect.
PubMed:Ginsenoside F1 protects human HaCaT keratinocytes from ultraviolet-B-induced apoptosis by maintaining constant levels of Bcl-2.
PubMed:Degradation of ginsenosides in humans after oral administration.
PubMed:Enzymatic preparation of ginsenosides Rg2, Rh1, and F1 from protopanaxatriol-type ginseng saponin mixture.
PubMed:Enzymatic preparation of ginsenosides Rg2, Rh1, and F1.
PubMed:[Saponins with low sugar chain from the leaves of Panax notoginseng (Burk) F. H. Chen].
PubMed:Effects of ginsenosides from Panax ginseng on cell-to-cell communication function mediated by gap junctions.
PubMed:[Studies on saponins from the leaves of Panax japonicus var. bipinnatifidus(Seem.)Wu et Feng].
PubMed:[Isolation and identification of saponin IV, V, VI and VII in ginseng stems].
 
Notes:
None found
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