(20R)-ginsenoside Rh2, 112246-15-8

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CODE187835 CODE187835
Product(s):
112246-15-8 20(R)-Ginsenoside Rh2 >98%
Ginsenoside Rh2 possesses matrix metalloproteinase inhibitory, anti-inflammatory and antioxidative activity. It had a significant inhibitory effect on the proliferation.

CAS Number:	112246-15-8	3D/inchi
FDA UNII:	Search
Nikkaji Web:	J466.392F
XlogP3-AA:	5.60 (est)
Molecular Weight:	622.88374000
Formula:	C36 H62 O8
NMR Predictor:	Predict (works with chrome, Edge or firefox)

Category:natural substances and extractives

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
Google Books:	Search
Google Scholar: with word "volatile"	Search
Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search

Physical Properties:

Assay:	95.00 to 100.00
Food Chemicals Codex Listed:	No
Soluble in:
	water, 0.004538 mg/L @ 25 °C (est)

Organoleptic Properties:

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

None found

Suppliers:

Alfa Biotechnology

For experimental / research use only.

20(R)-Ginsenoside Rh2 98%

BOC Sciences

For experimental / research use only.

20(R)-Ginsenoside Rh2 >98%

Odor: characteristic

Use: Ginsenoside Rh2 possesses matrix metalloproteinase inhibitory, anti-inflammatory and antioxidative activity. It had a significant inhibitory effect on the proliferation.

Santa Cruz Biotechnology

For experimental / research use only.

(20R)-Ginsenoside Rh2

Safety Information:


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
natural substances and extractives
Recommendation for (20R)-ginsenoside Rh2 usage levels up to:
	not for fragrance use.

Recommendation for (20R)-ginsenoside Rh2 flavor usage levels up to:
	not for flavor use.

Safety References:

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :54580480

National Institute of Allergy and Infectious Diseases:Data

(2R,3R,4S,5S,6R)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol

Chemidplus:0112246158

References:

	(2R,3R,4S,5S,6R)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	54580480
Pubchem (cas):	112246-15-8

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
CHEMBL:	View
HMDB (The Human Metabolome Database):	HMDB39544
FooDB:	FDB019172
VCF-Online:	VCF Volatile Compounds in Food
ChemSpider:	View

Potential Blenders and core components note

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):note

panax ginseng
Search Trop Picture

Synonyms:

(2R,3R,4S,5S,6R)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-	hydroxy-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
20(R)-	protopanaxdiol-3-O-beta-D-glycopyranoside

Articles:

PubMed:The interaction of serum albumin with ginsenoside Rh2 resulted in the downregulation of ginsenoside Rh2 cytotoxicity.

PubMed:Antitumoral Activity of (20R)- and (20S)-Ginsenoside Rh2 on Transplanted Hepatocellular Carcinoma in Mice.

PubMed:Semisynthesis and bioactive evaluation of oxidized products from 20(S)-ginsenoside Rg3, Rh2, protopanaxadiol (PPD) and their 20(R)-epimers as cytotoxic agents.

PubMed:Effects of ginsenosides from Panax ginseng on cell-to-cell communication function mediated by gap junctions.

Notes:

None found