EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

ginsenoside F2

Supplier Sponsors

CAS Number: 62025-49-4Picture of molecule3D/inchi
FDA UNII: Search
Nikkaji Web:J38.857B
XlogP3-AA:4.00 (est)
Molecular Weight:785.02544000
Formula:C42 H72 O13
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 0.0333 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Ginsenoside F2 98%
BOC Sciences
For experimental / research use only.
Ginsenoside F2
Santa Cruz Biotechnology
For experimental / research use only.
Ginsenoside F2 ≥98%
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for ginsenoside F2 usage levels up to:
 not for fragrance use.
 
Recommendation for ginsenoside F2 flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :9918692
National Institute of Allergy and Infectious Diseases:Data
 
References:
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):9918692
Pubchem (cas):62025-49-4
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C20779
HMDB (The Human Metabolome Database):HMDB39545
FooDB:FDB019164
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 panax ginseng
Search Trop Picture
 
Synonyms:
(3beta,12beta)-20-(beta-D-glucopyranosyloxy)-12-hydroxydammar
3beta,20-bis(beta-D-glucopyranosyloxy)dammar-24-en-12beta-ol
 

Articles:

PubMed:Ginseng polysaccharides enhanced ginsenoside Rb1 and microbial metabolites exposure through enhancing intestinal absorption and affecting gut microbial metabolism.
PubMed:Ciceribacter azotifigens sp. nov., a nitrogen-fixing bacterium isolated from activated sludge.
PubMed:Comparative study on chemical components and anti-inflammatory effects of Panax notoginseng flower extracted by water and methanol.
PubMed:Chryseobacterium ginsengiterrae sp. nov., with Beta-Glucosidase Activity Isolated from Soil of a Ginseng Field.
PubMed:Daejeonia ginsenosidivorans gen. nov., sp. nov., a ginsenoside-transforming bacterium isolated from lake water.
PubMed:Ginsenoside F2 induces the release of mediators associated with Anaphylactoid reactions.
PubMed:Production of the Rare Ginsenoside Rh2-MIX (20(S)-Rh2, 20(R)-Rh2, Rk2, and Rh3) by Enzymatic Conversion Combined with Acid Treatment and Evaluation of Its Anti-Cancer Activity.
PubMed:Fermentation of protopanaxadiol type ginsenosides (PD) with probiotic Bifidobacterium lactis and Lactobacillus rhamnosus.
PubMed:iTRAQ-Based Proteomic Analysis of Ginsenoside F2on Human Gastric Carcinoma Cells SGC7901.
PubMed:Cloning and Characterization of Ginsenoside-Hydrolyzing β-Glucosidase fromLactobacillus brevisThat Transforms Ginsenosides Rb1 and F2 into Ginsenoside Rd and Compound K.
PubMed:Ginsenosides, ingredients of the root of Panax ginseng, are not substrates but inhibitors of sodium-glucose transporter 1.
PubMed:Protective effects of ginsenoside F2 on 12-O-tetradecanoylphorbol-13-acetate-induced skin inflammation in mice.
PubMed:Sphingobacterium jejuense sp. nov., with ginsenoside-converting activity, isolated from compost.
PubMed:Biotransformation of ginsenoside Rb1 to ginsenoside C-K by endophytic fungus Arthrinium sp. GE 17-18 isolated from Panax ginseng.
PubMed:Pseudobacter ginsenosidimutans gen. nov., sp. nov., isolated from ginseng cultivating soil.
PubMed:The chemoattractant potential of ginsenosides in the ginseng - Pythium irregulare pathosystem.
PubMed:Production of Ginsenoside F2 by Using Lactococcus lactis with Enhanced Expression of β-Glucosidase Gene from Paenibacillus mucilaginosus.
PubMed:Ninjin'yoeito and ginseng extract prevent oxaliplatin-induced neurodegeneration in PC12 cells.
PubMed:Effects of broad-spectrum antibiotics on the metabolism and pharmacokinetics of ginsenoside Rb1: a study on rats׳ gut microflora influenced by lincomycin.
PubMed:The Bioconversion of Red Ginseng Ethanol Extract into Compound K by Saccharomyces cerevisiae HJ-014.
PubMed:Characterization of recombinant β-glucosidase from Arthrobacter chlorophenolicus and biotransformation of ginsenosides Rb1, Rb 2, Rc, and Rd.
PubMed:Ginsenoside F2 reduces hair loss by controlling apoptosis through the sterol regulatory element-binding protein cleavage activating protein and transforming growth factor-β pathways in a dihydrotestosterone-induced mouse model.
PubMed:Ginsenoside F2 possesses anti-obesity activity via binding with PPARγ and inhibiting adipocyte differentiation in the 3T3-L1 cell line.
PubMed:The inductive effect of ginsenoside F2 on hair growth by altering the WNT signal pathway in telogen mouse skin.
PubMed:Highly selective hydrolysis for the outer glucose at the C-20 position in ginsenosides by β-glucosidase from Thermus thermophilus and its application to the production of ginsenoside F2 from gypenoside XVII.
PubMed:[Chemical constituents from processed rhizomes of Panax notoginseng].
PubMed:Characterization of a ginsenoside-transforming β-glucosidase from Paenibacillus mucilaginosus and its application for enhanced production of minor ginsenoside F₂.
PubMed:Enzyme-modified Panax ginseng inhibits UVB-induced skin aging through the regulation of procollagen type I and MMP-1 expression.
PubMed:Biotransformation of ginsenoside Rb1 via the gypenoside pathway by human gut bacteria.
PubMed:Ginsenoside F(2) induces apoptosis in humor gastric carcinoma cells through reactive oxygen species-mitochondria pathway and modulation of ASK-1/JNK signaling cascade in vitro and in vivo.
PubMed:Biotransformation of saponins by endophytes isolated from Panax notoginseng.
PubMed:Enzymatic Biotransformation of Ginsenoside Rb1 and Gypenoside XVII into Ginsenosides Rd and F2 by Recombinant β-glucosidase from Flavobacterium johnsoniae.
PubMed:[Screening of pregnane X receptor activation from ginsenosides].
PubMed:Biotransformation and metabolic profile of American ginseng saponins with human intestinal microflora by liquid chromatography quadrupole time-of-flight mass spectrometry.
PubMed:Microbial transformation of ginsenoside Rb1 to compound K by Lactobacillus paralimentarius.
PubMed:Lactobacillus ginsenosidimutans sp. nov., isolated from kimchi with the ability to transform ginsenosides.
PubMed:Purification and characterization of a ginsenoside Rb(1)-hydrolyzing β-glucosidase from Aspergillus niger KCCM 11239.
PubMed:Ginsenosidases and the pathogenicity of Pythium irregulare.
PubMed:Ginsenoside F2 induces apoptosis accompanied by protective autophagy in breast cancer stem cells.
PubMed:Anti-Cancer Effect of Ginsenoside F2 against Glioblastoma Multiforme in Xenograft Model in SD Rats.
PubMed:Biotransformation of Ginsenoside Rb1 to Prosapogenins, Gypenoside XVII, Ginsenoside Rd, Ginsenoside F2, and Compound K by Leuconostoc mesenteroides DC102.
PubMed:Phycicoccus ginsenosidimutans sp. nov., isolated from soil of a ginseng field.
PubMed:Partial purification and characterization of three ginsenoside-metabolizing beta-glucosidases from Pythium irregulare.
PubMed:Comparative analysis on microbial and rat metabolism of ginsenoside Rb1 by high-performance liquid chromatography coupled with tandem mass spectrometry.
PubMed:Development and validation of a reversed-phase HPLC method for quantitative determination of ginsenosides Rb1, Rd, F2, and compound K during the process of biotransformation of ginsenoside Rb1.
PubMed:Microbial conversion of ginsenoside Rb1 to minor ginsenoside F2 and gypenoside XVII by Intrasporangium sp. GS603 isolated from soil.
PubMed:Marked production of ginsenosides Rd, F2, Rg3, and compound K by enzymatic method.
PubMed:Conversion of major ginsenoside Rb1 to ginsenoside F2 by Caulobacter leidyia.
PubMed:In vitro metabolism of ginsenosides by the ginseng root pathogen Pythium irregulare.
PubMed:[Metabolism of ginsenoside Rb1 and panaxadiol saponins by fungi].
PubMed:[Minor saponins from leaves of Panax ginseng C.A. Meyer].
PubMed:Studies on absorption, distribution, excretion and metabolism of ginseng saponins. VII. Comparison of the decomposition modes of ginsenoside-Rb1 and -Rb2 in the digestive tract of rats.
PubMed:Studies on absorption, distribution, excretion and metabolism of ginseng saponins. V. The decomposition products of ginsenoside Rb2 in the large intestine of rats.
 
Notes:
None found
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