EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

punicalin

Supplier Sponsors

CAS Number: 65995-64-4Picture of molecule3D/inchi
FDA UNII: Search
Nikkaji Web:J353.470G
XlogP3-AA:-0.30 (est)
Molecular Weight:782.53174000
Formula:C34 H22 O22
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 3213 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Punicalin 98%
BOC Sciences
For experimental / research use only.
Punicalin >98%
Odor: characteristic
Use: Punicalin is an ellagitannin. It is a highly active carbonic anhydrase inhibitor. It have strong antioxidative activity. Punicalin have anti-hepatotoxic activity but that the larger dose of punicalin induced liver damage.
Sigma-Aldrich
For experimental / research use only.
Punicalin, mixture of anomers analytical standard
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for punicalin usage levels up to:
 not for fragrance use.
 
Recommendation for punicalin flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5464368
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
Chemidplus:0065995644
 
References:
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5464368
Pubchem (cas):65995-64-4
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
HMDB (The Human Metabolome Database):HMDB39205
FooDB:FDB018735
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 punica granatum peel
Search Trop Picture
 terminalia catappa
Search Trop Picture
 
Synonyms:
D-glucose, cyclic 4,6-(2,2'-(5,10-dihydro-2,3,7,8-tetrahydroxy-5,10-dioxo(1)benzopyrano(5,4,3-cde)(1)benzopyran-1,6-diyl)bis(3,4,5-trihydroxybenzoate)), (4(S,S))-
 

Articles:

PubMed:Lafoensia pacari A. St. -Hil: wound healing activity and mechanism of action of standardized hydroethanolic leaves extract.
PubMed:On-line monitoring of Aspergillus niger GH1 growth in a bioprocess for the production of ellagic acid and ellagitannase by solid-state fermentation.
PubMed:Impact of extraction techniques on antioxidant capacities and phytochemical composition of polyphenol-rich extracts.
PubMed:Qualitative Analysis of Polyphenols in Macroporous Resin Pretreated Pomegranate Husk Extract by HPLC-QTOF-MS.
PubMed:Characterisation of Pomegranate-Husk Polyphenols and Semi-Preparative Fractionation of Punicalagin.
PubMed:Phytochemical Characterization ofTerminalia catappaLinn. Extracts and Their antifungal Activities againstCandidaspp.
PubMed:Multiple Activities of Punica granatum Linne against Acne Vulgaris.
PubMed:A nematicidal tannin from Punica granatum L. rind and its physiological effect on pine wood nematode (Bursaphelenchus xylophilus).
PubMed:Identification of hydrolyzable tannins (punicalagin, punicalin and geraniin) as novel inhibitors of hepatitis B virus covalently closed circular DNA.
PubMed:Punica granatum L. Hydrogel for Wound Care Treatment: From Case Study to Phytomedicine Standardization.
PubMed:A systematic determination of polyphenols constituents and cytotoxic ability in fruit parts of pomegranates derived from five Chinese cultivars.
PubMed:Effect of drying on the bioactive compounds, antioxidant, antibacterial and antityrosinase activities of pomegranate peel.
PubMed:Cost-effective imprinting combining macromolecular crowding and a dummy template for the fast purification of punicalagin from pomegranate husk extract.
PubMed:The complete biodegradation pathway of ellagitannins by Aspergillus niger in solid-state fermentation.
PubMed:Soy protein isolate does not affect ellagitannin bioavailability and urolithin formation when mixed with pomegranate juice in humans.
PubMed:Anti-Glycation Effects of Pomegranate (Punica granatum L.) Fruit Extract and Its Components in Vivo and in Vitro.
PubMed:Pomegranate ellagitannins stimulate growth of gut bacteria in vitro: Implications for prebiotic and metabolic effects.
PubMed:Pomegranate ellagitannins inhibit α-glucosidase activity in vitro and reduce starch digestibility under simulated gastro-intestinal conditions.
PubMed:Terminalia catappa L.: a medicinal plant from the Caribbean pharmacopeia with anti-Helicobacter pylori and antiulcer action in experimental rodent models.
PubMed:An extract of pomegranate fruit and galangal rhizome increases the numbers of motile sperm: a prospective, randomised, controlled, double-blinded trial.
PubMed:Small molecule inhibitors of HCV replication from pomegranate.
PubMed:Ellagitannin oligomers and a neolignan from pomegranate arils and their inhibitory effects on the formation of advanced glycation end products.
PubMed:Fungal biodegradation of pomegranate ellagitannins.
PubMed:Purification, antioxidant activity and protein-precipitating capacity of punicalin from pomegranate husk.
PubMed:Absence of pomegranate ellagitannins in the majority of commercial Pomegranate extracts: implications for standardization and quality control.
PubMed:Effects of pomegranate chemical constituents/intestinal microbial metabolites on CYP1B1 in 22Rv1 prostate cancer cells.
PubMed:Environmental conditions affect the color, taste, and antioxidant capacity of 11 pomegranate accessions' fruits.
PubMed:Pomegranate phenolics from the peels, arils, and flowers are antiatherogenic: studies in vivo in atherosclerotic apolipoprotein e-deficient (E 0) mice and in vitro in cultured macrophages and lipoproteins.
PubMed:A new strategy to inhibit the excision reaction catalysed by HIV-1 reverse transcriptase: compounds that compete with the template-primer.
PubMed:A new method of standartization of health-promoting pomegranate fruit (Punica granatum) extract.
PubMed:Pomegranate fruit extract modulates UV-B-mediated phosphorylation of mitogen-activated protein kinases and activation of nuclear factor kappa B in normal human epidermal keratinocytes paragraph sign.
PubMed:Two ellagitannins from the leaves of Terminalia triflora with inhibitory activity on HIV-1 reverse transcriptase.
PubMed:Two ellagitannins from Punica granatum heartwood.
PubMed:Antioxidant and hepatoprotective effects of punicalagin and punicalin on acetaminophen-induced liver damage in rats.
PubMed:Antioxidant and free radical scavenging effects of the tannins of Terminalia catappa L.
PubMed:Effects of punicalagin and punicalin on carrageenan-induced inflammation in rats.
PubMed:Antioxidant and hepatoprotective activity of punicalagin and punicalin on carbon tetrachloride-induced liver damage in rats.
PubMed:Carbonic anhydrase inhibitors from the pericarps of Punica granatum L.
PubMed:Prevention of binding of rgp120 by anti-HIV active tannins.
PubMed:Anti-AIDS agents, 2: Inhibitory effects of tannins on HIV reverse transcriptase and HIV replication in H9 lymphocyte cells.
 
Notes:
None found
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