ganoderiol F, 114567-47-4

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CODE187070 CODE187070
Product(s):
114567-47-4 Ganoderiol F >98%
Lansiumarin C is a natural coumarin found in the branches of Clausena lansium. and found to induce senescence of cancer cell lines, it induces growth arrest of cancer cell lines HepG2, Huh7 and K562; activation of the mitogen-activated protein kinase EKR anti-inflammatory; anti-HIV;

CAS Number:	114567-47-4	3D/inchi
FDA UNII:	Search
XlogP3-AA:	5.80 (est)
Molecular Weight:	454.69422000
Formula:	C30 H46 O3
NMR Predictor:	Predict (works with chrome, Edge or firefox)

Category:natural substances and extractives

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
Google Books:	Search
Google Scholar: with word "volatile"	Search
Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search

Physical Properties:

Assay:	95.00 to 100.00
Food Chemicals Codex Listed:	No
Soluble in:
	water, 0.001935 mg/L @ 25 °C (est)

Organoleptic Properties:

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

None found

Suppliers:

BOC Sciences

For experimental / research use only.

Ganoderiol F >98%

Odor: characteristic

Use: Lansiumarin C is a natural coumarin found in the branches of Clausena lansium. and found to induce senescence of cancer cell lines, it induces growth arrest of cancer cell lines HepG2, Huh7 and K562; activation of the mitogen-activated protein kinase EKR anti-inflammatory; anti-HIV;

Coompo

For experimental / research use only.

Ganoderiol F 98%

Safety Information:


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
natural substances and extractives
Recommendation for ganoderiol F usage levels up to:
	not for fragrance use.

Recommendation for ganoderiol F flavor usage levels up to:
	not for flavor use.

Safety References:

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :471008

National Institute of Allergy and Infectious Diseases:Data

(5R,10S,13R,14R,17R)-17-[(2R)-7-hydroxy-6-(hydroxymethyl)hept-5-en-2-yl]-4,4,10,13,14-pentamethyl-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-3-one

Chemidplus:0114567474

References:

	(5R,10S,13R,14R,17R)-17-[(2R)-7-hydroxy-6-(hydroxymethyl)hept-5-en-2-yl]-4,4,10,13,14-pentamethyl-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-3-one
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	471008
Pubchem (cas):	114567-47-4

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
CHEMBL:	View
HMDB (The Human Metabolome Database):	HMDB38707
FooDB:	FDB018115
VCF-Online:	VCF Volatile Compounds in Food

Potential Blenders and core components note

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):note

ganoderma lucidum
Search PMC Picture

Synonyms:

26,27-	dihydroxylanosta-7,9(11),24-trien-3-one
(5R,10S,13R,14R,17R)-17-[(2R)-7-	hydroxy-6-(hydroxymethyl)hept-5-en-2-yl]-4,4,10,13,14-pentamethyl-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-3-one

Articles:

PubMed:Tubulin polymerization-stimulating activity of Ganoderma triterpenoids.

PubMed:Anti-inflammatory and heme oxygenase-1 inducing activities of lanostane triterpenes isolated from mushroom Ganoderma lucidum in RAW264.7 cells.

PubMed:Pharmacophore-based discovery of FXR-agonists. Part II: identification of bioactive triterpenes from Ganoderma lucidum.

PubMed:Anti-human immunodeficiency virus-1 protease activity of new lanostane-type triterpenoids from Ganoderma sinense.

PubMed:Metabolism and pharmacokinetics in rats of ganoderiol F, a highly cytotoxic and antitumor triterpene from Ganoderma lucidum.

PubMed:Anti-androgen effects of extracts and compounds from Ganoderma lucidum.

PubMed:Ganoderiol F, a ganoderma triterpene, induces senescence in hepatoma HepG2 cells.

PubMed:Anticomplement activity of terpenoids from the spores of Ganoderma lucidum.

PubMed:Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum.

Notes:

None found