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Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | water, 11.89 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for planinin usage levels up to: | | | not for fragrance use.
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| Recommendation for planinin flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :129290 |
| National Institute of Allergy and Infectious Diseases:Data |
| 5-[(3R,3aS,6S,6aS)-6-(3,4-dimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-1,3-benzodioxole |
| Chemidplus:0068296275 |
References:
| | 5-[(3R,3aS,6S,6aS)-6-(3,4-dimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-1,3-benzodioxole |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 129290 |
| Pubchem (cas): | 68296-27-5 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| (+)- | fargesin | | 1,3- | benzodioxole, 5-(4-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo(3,4-c)furan-1-yl)-, (1S-(1alpha,3aalpha,4beta,6aalpha))- | | 2-(3',4'- | dimethoxyphenyl)-6-(3'',4''-methylenedioxyphenyl)-3,7-dioxabicyclo(3,3,0)octane | | 5-[(3R,3aS,6S,6aS)-6-(3,4- | dimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-1,3-benzodioxole |
Articles:
| PubMed:Antifeedant Activities of Lignans from Stem Bark of Zanthoxylum armatum DC. against Tribolium castaneum. |
| PubMed:Escalation of liver malfunctioning: A step toward Herbal Awareness. |
| PubMed:Inhibitory Effects of Dimethyllirioresinol, Epimagnolin A, Eudesmin, Fargesin, and Magnolin on Cytochrome P450 Enzyme Activities in Human Liver Microsomes. |
| PubMed:Fargesin exerts anti-inflammatory effects in THP-1 monocytes by suppressing PKC-dependent AP-1 and NF-ĸB signaling. |
| PubMed:Simultaneous quantification and identification of flavonoids, lignans, coumarin and amides in leaves of Zanthoxylum armatum using UPLC-DAD-ESI-QTOF-MS/MS. |
| PubMed:Antihypertensive effects of fargesin in vitro and in vivo via attenuating oxidative stress and promoting nitric oxide release. |
| PubMed:Analysis of lignans in Magnoliae Flos by turbulent flow chromatography with online solid-phase extraction and high-performance liquid chromatography with tandem mass spectrometry. |
| PubMed:A new dimeric lignan from Zanthoxylum simulans. |
| PubMed:Ultrasound-Assisted Aqueous Two-Phase System for Extraction and Enrichment of Zanthoxylum armatum Lignans. |
| PubMed:Fargesin as a potential β₁ adrenergic receptor antagonist protects the hearts against ischemia/reperfusion injury in rats via attenuating oxidative stress and apoptosis. |
| PubMed:A new geranylbenzofuranone from Zanthoxylum armatum. |
| PubMed:New prenylated carbazole alkaloids from Zanthoxylum armatum. |
| PubMed:[Study on chemical constituents of Zanthoxyli cortex's ethyl acetate extract]. |
| PubMed:Quantitative and structural analysis of amides and lignans in Zanthoxylum armatum by UPLC-DAD-ESI-QTOF-MS/MS. |
| PubMed:Tetrahydrofurofuran-type lignans inhibit breast cancer-mediated bone destruction by blocking the vicious cycle between cancer cells, osteoblasts and osteoclasts. |
| PubMed:Intramolecular Larock indole synthesis: preparation of 3,4-fused tricyclic indoles and total synthesis of fargesine. |
| PubMed:Fargesin, a component of Flos Magnoliae, stimulates glucose uptake in L6 myotubes. |
| PubMed:Fargesin improves lipid and glucose metabolism in 3T3-L1 adipocytes and high-fat diet-induced obese mice. |
| PubMed:Antiprotozoal and Antimycobacterial Activities of Pure Compounds from Aristolochia elegans Rhizomes. |
| PubMed:Antinociceptive and anti-inflammatory activities of ethyl acetate fraction from Zanthoxylum armatum in mice. |
| PubMed:Liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry for the simultaneous determination of dimethoxyaschantin, dimethylliroresinol, dimethylpinoresinol, epimagnolin A, fargesin and magnolin in rat plasma. |
| PubMed:Anti-Candida property of a lignan glycoside derived from Styrax japonica S. et Z. via membrane-active mechanisms. |
| PubMed:Antitrypanosomal activity of a diterpene and lignans isolated from Aristolochia cymbifera. |
| PubMed:Suppression of inducible nitric oxide synthase expression by furfuran lignans from flower buds of Magnolia fargesii in BV-2 microglial cells. |
| PubMed:Antifungal effect with apoptotic mechanism(s) of Styraxjaponoside C. |
| PubMed:5-lipoxygenase-inhibitory constituents from Schizandra fructus and Magnolia flos. |
| PubMed:Extracts of Magnoliae flos inhibit inducible nitric oxide synthase via ERK in human respiratory epithelial cells. |
| PubMed:Chemistry and bioactivity of Flos Magnoliae, a Chinese herb for rhinitis and sinusitis. |
| PubMed:Inhibitions of mast cell-derived histamine release by different Flos Magnoliae species in rat peritoneal mast cells. |
| PubMed:Evaluation of insecticidal activity of diterpenes and lignans from Aristolochia malmeana against Anticarsia gemmatalis. |
| PubMed:Isolation and purification of lignans from Magnolia biondii Pamp by isocratic reversed-phase two-dimensional liquid chromatography following microwave-assisted extraction. |
| PubMed:A new lignan glycoside from the stem bark of Styrax japonica S. et Z. |
| PubMed:Allelochemicals from Stauranthus perforatus, a Rutaceous tree of the Yucatan Peninsula, Mexico. |
| PubMed:C-H insertion approach to the synthesis of endo,exo-furofuranones: synthesis of (+/-)-asarinin, (+/-)-epimagnolin A, and (+/-)-fargesin. |
| PubMed:Determination of 1,3-benzodioxanes in Piper mullesua by high-performance thin-layer chromatography. |
| PubMed:Inhibition of low density lipoprotein oxidation by tetrahydrofurofuran lignans from Forsythia suspensa and Magnolia coco. |
| PubMed:A new amide from zanthoxylum armatum |
| PubMed:Two new constituents from the leaves of magnolia coco |
| PubMed:[Biologically active lignins from Magnolia biondii Pamp]. |
| PubMed:[Studies on the chemical constituents of Zanthoxylum planispinum Sieb. et Zucc]. |
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3D/inchi