EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

beta-mangostin

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CAS Number: 20931-37-7Picture of molecule3D/inchi
FDA UNII: Search
Nikkaji Web:J15.918B
XlogP3-AA:6.60 (est)
Molecular Weight:424.49336000
Formula:C25 H28 O6
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
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Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 5.494e-005 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Beta-mangostin 98%
BOC Sciences
For experimental / research use only.
beta-mangostin >98%
Odor: characteristic
Use: Beta-mangostin, a natural product extracted from the fruits of Garcinia mangostana, can reduced the levels of TNF-à and IL-1? in peritoneal fluid.
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for beta-mangostin usage levels up to:
 not for fragrance use.
 
Recommendation for beta-mangostin flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5495925
National Institute of Allergy and Infectious Diseases:Data
1,6-dihydroxy-3,7-dimethoxy-2,8-bis(3-methylbut-2-enyl)xanthen-9-one
 
References:
 1,6-dihydroxy-3,7-dimethoxy-2,8-bis(3-methylbut-2-enyl)xanthen-9-one
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5495925
Pubchem (cas):20931-37-7
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
HMDB (The Human Metabolome Database):HMDB36596
FooDB:FDB015508
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 garcinia mangostana
Search Trop Picture
 
Synonyms:
1,6-dihydroxy-3,7-dimethoxy-2,8-bis(3-methylbut-2-enyl)xanthen-9-one
 

Articles:

PubMed:Garcixanthone A, a new cytotoxic xanthone from the pericarps of Garcinia mangostana.
PubMed:Beta-mangostin from Cratoxylum arborescens activates the intrinsic apoptosis pathway through reactive oxygen species with downregulation of the HSP70 gene in the HL60 cells associated with a G0/G1cell-cycle arrest.
PubMed:Isolation and structural modifications of ananixanthone from Calophyllum teysmannii and their cytotoxic activities.
PubMed:β-mangostin suppresses human hepatocellular carcinoma cell invasion through inhibition of MMP-2 and MMP-9 expression and activating the ERK and JNK pathways.
PubMed:Beta-mangostin demonstrates apoptogenesis in murine leukaemia (WEHI-3) cells in vitro and in vivo.
PubMed:Acetyl- and O-alkyl- derivatives of β-mangostin from Garcinia mangostana and their anti-inflammatory activities.
PubMed:New xanthones and cytotoxic constituents from Garcinia mangostana fruit hulls against human hepatocellular, breast, and colorectal cancer cell lines.
PubMed:Mangostanaxanthones III and IV: advanced glycation end-product inhibitors from the pericarp of Garcinia mangostana.
PubMed:Depigmentation of α-melanocyte-stimulating hormone-treated melanoma cells by β-mangostin is mediated by selective autophagy.
PubMed:Evidence of the gastroprotective and anti- Helicobacter pylori activities of β-mangostin isolated from Cratoxylum arborescens (vahl) blume.
PubMed:Screening of mammalian DNA polymerase and topoisomerase inhibitors from Garcinia mangostana L. and analysis of human cancer cell proliferation and apoptosis.
PubMed:Antibacterial tetraoxygenated xanthones from the immature fruits of Garcinia cowa.
PubMed:Metabolite footprinting of Plasmodium falciparum following exposure to Garcinia mangostana Linn. crude extract.
PubMed:In vitro antiplasmodial activity of benzophenones and xanthones from edible fruits of Garcinia species.
PubMed:A new coumarin from Calophyllum hosei.
PubMed:A new furanoxanthone from Garcinia mangostana.
PubMed:β Mangostin suppress LPS-induced inflammatory response in RAW 264.7 macrophages in vitro and carrageenan-induced peritonitis in vivo.
PubMed:A concise and efficient total synthesis of α-mangostin and β-mangostin from Garcinia mangostana.
PubMed:Benzophenone and xanthone derivatives from the inflorescences of Garcinia cowa.
PubMed:Apoptosis, antimicrobial and antioxidant activities of phytochemicals from Garcinia malaccensis Hk.f.
PubMed:Cytotoxic xanthone constituents of the stem bark of Garcinia mangostana (mangosteen).
PubMed:Cytotoxic geranylated xanthones and O-alkylated derivatives of alpha-mangostin.
PubMed:Anti-cancer effects of xanthones from pericarps of mangosteen.
PubMed:Garcinia mangostana: a source of potential anti-cancer lead compounds against CEM-SS cell line.
PubMed:HPLC analysis of selected xanthones in mangosteen fruit.
PubMed:Antioxidant xanthones from Cratoxylum cochinchinense.
PubMed:Quantitative and qualitative determination of six xanthones in Garcinia mangostana L. by LC-PDA and LC-ESI-MS.
PubMed:Xanthones from Garcinia mangostana (Guttiferae).
PubMed:Cytotoxic and antimalarial prenylated xanthones from Cratoxylum cochinchinense.
PubMed:Xanthones induce cell-cycle arrest and apoptosis in human colon cancer DLD-1 cells.
PubMed:A geranylated biphenyl derivative from Garcinia malvgostana.
PubMed:Antimalarial xanthones from Garcinia cowa.
 
Notes:
None found
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