EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

ganodermanontriol

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CAS Number: 106518-63-2Picture of molecule3D/inchi
Other(deleted CASRN):1192133-46-2
FDA UNII: Search
Nikkaji Web:J1.005.780I
MDL:MFCD07779162
XlogP3-AA:4.80 (est)
Molecular Weight:472.70936000
Formula:C30 H48 O4
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 0.008667 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Ganodermanontriol 98%
BOC Sciences
For experimental / research use only.
Ganodermanontriol >98%
Odor: characteristic
Use: Ganodermanontriol, a natural triterpene isolated from Ganoderma lucidum, it has the activities of anti-HIV-1, anti-oxidative and anti-complement, and also can induce anti-inflammatory activity in t-BHP-damaged hepatic cells through the expression of HO- anti-HIV-1, anti-oxidative, anti-complement
Carbosynth
For experimental / research use only.
Ganodermanontriol
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for ganodermanontriol usage levels up to:
 not for fragrance use.
 
Recommendation for ganodermanontriol flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :73177
National Institute of Allergy and Infectious Diseases:Data
(5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-[(2R,5S)-5,6,7-trihydroxy-6-methylheptan-2-yl]-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-3-one
Chemidplus:0106518632
 
References:
 (5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-[(2R,5S)-5,6,7-trihydroxy-6-methylheptan-2-yl]-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-3-one
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):73177
Pubchem (cas):106518-63-2
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):HMDB35977
FooDB:FDB014781
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 ganoderma lucidum
Search PMC Picture
 
Synonyms:
 lanosta-7,9(11)-dien-3-one, 24,25,26-trihydroxy-, (24S,25R)-
(5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-[(2R,5S)-5,6,7-trihydroxy-6-methylheptan-2-yl]-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-3-one
 

Articles:

PubMed:Triterpenoids fromGanoderma luciduminhibit the activation of EBV antigens as telomerase inhibitors.
PubMed:Tubulin polymerization-stimulating activity of Ganoderma triterpenoids.
PubMed:Effects of Ganodermanondiol, a New Melanogenesis Inhibitor from the Medicinal Mushroom Ganoderma lucidum.
PubMed:Distinct Responses of Cytotoxic Ganoderma lucidum Triterpenoids in Human Carcinoma Cells.
PubMed:In vitro and in vivo hepatoprotective effect of ganodermanontriol against t-BHP-induced oxidative stress.
PubMed:Semisynthesis and biological evaluation of ganodermanontriol and its stereoisomeric triols.
PubMed:Ganodermanontriol (GDNT) exerts its effect on growth and invasiveness of breast cancer cells through the down-regulation of CDC20 and uPA.
PubMed:Pharmacophore-based discovery of FXR-agonists. Part II: identification of bioactive triterpenes from Ganoderma lucidum.
PubMed:Ganodermanontriol, a lanostanoid triterpene from Ganoderma lucidum, suppresses growth of colon cancer cells through ß-catenin signaling.
PubMed:Triterpene-farnesyl hydroquinone conjugates from Ganoderma sinense.
PubMed:New triterpene aldehydes, lucialdehydes A-C, from Ganoderma lucidum and their cytotoxicity against murine and human tumor cells.
PubMed:Anticomplement activity of terpenoids from the spores of Ganoderma lucidum.
PubMed:Triterpene antioxidants from ganoderma lucidum.
PubMed:Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum.
PubMed:Triterpenes from the spores of Ganoderma lucidum and their inhibitory activity against HIV-1 protease.
 
Notes:
None found
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