EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

rebaudioside B

Supplier Sponsors

CAS Number: 58543-17-2Picture of molecule3D/inchi
FDA UNII: U2N4XKX7HP
Nikkaji Web:J13.836C
XlogP3:-1.00 (est)
Molecular Weight:804.88180000
Formula:C38 H60 O18
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
FEMA Number:4978
FDA:No longer provide for the use of these seven synthetic flavoring substances
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 68.35 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Rebaudioside B 98%
BOC Sciences
For experimental / research use only.
Rebaudioside B
Sigma-Aldrich
For experimental / research use only.
Rebaudioside B analytical standard
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for rebaudioside B usage levels up to:
 not for fragrance use.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 30
Click here to view publication 30
 average usual ppmaverage maximum ppm
baked goods: 20.0000030.00000
beverages(nonalcoholic): 20.0000030.00000
beverages(alcoholic): 20.0000030.00000
breakfast cereal: 20.0000030.00000
cheese: --
chewing gum: 25.0000030.00000
condiments / relishes: 20.0000030.00000
confectionery froastings: 20.0000030.00000
egg products: --
fats / oils: --
fish products: --
frozen dairy: 20.0000030.00000
fruit ices: 20.0000030.00000
gelatins / puddings: 20.0000030.00000
granulated sugar: --
gravies: 20.0000030.00000
hard candy: 20.0000030.00000
imitation dairy: 20.0000030.00000
instant coffee / tea: 20.0000030.00000
jams / jellies: 20.0000030.00000
meat products: --
milk products: 20.0000030.00000
nut products: 20.0000030.00000
other grains: 20.0000030.00000
poultry: --
processed fruits: 20.0000030.00000
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: 20.0000030.00000
snack foods: 20.0000030.00000
soft candy: 20.0000030.00000
soups: 20.0000030.00000
sugar substitutes: --
sweet sauces: 20.0000030.00000
 
Safety References:
EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :21593623
National Institute of Allergy and Infectious Diseases:Data
(1R,4S,5R,9S,10R,13S)-13-[(2S,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-3,4-bis[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]oxan-2-yl]oxy-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acid
Chemidplus:0058543172
 
References:
 (1R,4S,5R,9S,10R,13S)-13-[(2S,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-3,4-bis[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]oxan-2-yl]oxy-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):21593623
Pubchem (cas):58543-17-2
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):HMDB34949
FooDB:FDB013542
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 stevia rebaudiana
Search Trop Picture
 
Synonyms:
(8alpha,9beta,10alpha,13alpha)-13-{[beta-D-glucopyranosyl-(1->2)-[beta-D-glucopyranosyl-(1->3)]-beta-D-glucopyranosyl]oxy}kaur-16-en-18-oic acid
(1R,4S,5R,9S,10R,13S)-13-[(2S,3R,4S,5R,6R)-5-hydroxy-6-(hydroxymethyl)-3,4-bis[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy]oxan-2-yl]oxy-5,9-dimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecane-5-carboxylic acid
 rebaudioside B 95%
 

Articles:

PubMed:Evaluation of the Antihyperglycemic Effect of Minor Steviol Glycosides in Normoglycemic and Induced-Diabetic Wistar Rats.
PubMed:Validation of HPLC-UV method for determination of minor glycosides contained in Stevia rebaudiana Bertoni leaves.
PubMed:In vitro metabolism of rebaudioside B, D, and M under anaerobic conditions: comparison with rebaudioside A.
PubMed:Hydrogenation of the exocyclic olefinic bond at C-16/C-17 position of ent-kaurane diterpene glycosides of Stevia rebaudiana using various catalysts.
PubMed:Simultaneous analysis of steviol and steviol glycosides by liquid chromatography with ultraviolet detection on a mixed-mode column: application to Stevia plant material and Stevia-containing dietary supplements.
PubMed:Catalytic hydrogenation of the sweet principles of Stevia rebaudiana, Rebaudioside B, Rebaudioside C, and Rebaudioside D and sensory evaluation of their reduced derivatives.
PubMed:Purification and some properties of a beta-glucosidase from Flavobacterium johnsonae.
 
Notes:
None found
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