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cucurbitacin B

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CAS Number: 6199-67-3Picture of molecule3D/inchi
FDA UNII: 0115W5MABF
XlogP3-AA:2.60 (est)
Molecular Weight:558.71222000
Formula:C32 H46 O8
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 0.376 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Cucurbitacin B 98%
BOC Sciences
For experimental / research use only.
Cucurbitacin B >98%
Odor: characteristic
Use: Cucurbitacin B, which can be extracted from the rhizomes of Hemsleya amabilis Diels, has profound in vitro and in vivo antiproliferative effects against human pancreatic cancer cells. Cucurbitacin B inhibits proliferation and induces apoptosis via STAT3 Antiproliferative
Santa Cruz Biotechnology
For experimental / research use only.
Cucurbitacin B
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for cucurbitacin B usage levels up to:
 not for fragrance use.
 
Recommendation for cucurbitacin B flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5281316
National Institute of Allergy and Infectious Diseases:Data
[(E,6R)-6-[(2S,8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate
Chemidplus:0006199673
 
References:
 [(E,6R)-6-[(2S,8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5281316
Pubchem (cas):6199-67-3
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C08794
HMDB (The Human Metabolome Database):HMDB34927
FooDB:FDB013515
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 ipomopsis aggregata
Search Trop Picture
 luffa aegyptiaca
Search Trop Picture
 
Synonyms:
 datisca principle B
1,2-dihydro-alpha-elaterin
[(E,6R)-6-[(2S,8S,9R,10R,13R,14S,16R,17R)-2,16-dihydroxy-4,4,9,13,14-pentamethyl-3,11-dioxo-2,7,8,10,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-hydroxy-2-methyl-5-oxohept-3-en-2-yl] acetate
19-norlanosta-5,23-diene-3,11,22-trione, 25-(acetyloxy)-2,16,20-trihydroxy-9-methyl-, (2beta,9beta,10alpha,16alpha,23E)- (9CI)
 

Articles:

PubMed:Association of textile industry effluent with mutagenicity and its toxic health implications upon acute and sub-chronic exposure.
PubMed:Natural Terpenoids Against Female Breast Cancer: a 5-year Recent Research.
PubMed:Cucurbitacin B suppresses metastasis mediated by reactive oxygen species (ROS) via focal adhesion kinase (FAK) in breast cancer MDA-MB-231 cells.
PubMed:Cucurbitacin B induces inhibitory effects via CIP2A/PP2A/Akt pathway in glioblastoma multiforme.
PubMed:Cucurbitacin B and SCH772984 exhibit synergistic anti-pancreatic cancer activities by suppressing EGFR, PI3K/Akt/mTOR, STAT3 and ERK signaling.
PubMed:Cucurbitacin-B attenuates CCl4-induced hepatic fibrosis in mice through inhibition of STAT-3.
PubMed:Cucurbitacin B acts a potential insect growth regulator by antagonizing 20-hydroxyecdysone activity.
PubMed:Exploring the Cytotoxic Potential of Triterpenoids-enriched Fraction ofBacopa monnieriby ImplementingIn vitro,In vivo, andIn silicoApproaches.
PubMed:Cucurbitacin B and cancer intervention: Chemistry, biology and mechanisms (Review).
PubMed:Simultaneous determination of cucurbitacin B and cucurbitacin E in rat plasma by UHPLC-MS/MS: A pharmacokinetics study after oral administration of cucurbitacin tablets.
PubMed:Inhibition of paclitaxel resistance and apoptosis induction by cucurbitacin B in ovarian carcinoma cells.
PubMed:Cucurbitacin B inhibits cell proliferation and induces apoptosis in human osteosarcoma cells via modulation of the JAK2/STAT3 and MAPK pathways.
PubMed:Antitumor effectiveness of a combined therapy with a new cucurbitacin B derivative and paclitaxel on a human lung cancer xenograft model.
PubMed:Cucurbitacins: elucidation of their interactions with the cytoskeleton.
PubMed:Cucurbitacin B induces autophagy and apoptosis by suppressing CIP2A/PP2A/mTORC1 signaling axis in human cisplatin resistant gastric cancer cells.
PubMed:Cucurbitacin B Protects Against Pressure Overload Induced Cardiac Hypertrophy.
PubMed:Simultaneous determination of cucurbitacin B, E, I and E-glucoside in plant material and body fluids by HPLC-MS.
PubMed:Protective Effects of Cucurbitacin B on Acute Lung Injury Induced by Sepsis in Rats.
PubMed:Cucurbitacin B synergistically enhances the apoptosis-inducing effect of arsenic trioxide by inhibiting STAT3 phosphorylation in lymphoma Ramos cells.
PubMed:Doxorubicin has a synergistic cytotoxicity with cucurbitacin B in anaplastic thyroid carcinoma cells.
PubMed:Cucurbitacin B purified from Ecballium elaterium (L.) A. Rich from Tunisia inhibits α5β1 integrin-mediated adhesion, migration, proliferation of human glioblastoma cell line and angiogenesis.
PubMed:PTEN Activation by DNA Damage Induces Protective Autophagy in Response to Cucurbitacin B in Hepatocellular Carcinoma Cells.
PubMed:Sestrin-3 modulation is essential for therapeutic efficacy of cucurbitacin B in lung cancer cells.
PubMed:Anticancer effect of cucurbitacin B on MKN-45 cells via inhibition of the JAK2/STAT3 signaling pathway.
PubMed:Therapeutic potential of Benincasa cerifera: A review.
PubMed:Cucurbitacin B exerts anti-cancer activities in human multiple myeloma cells in vitro and in vivo by modulating multiple cellular pathways.
PubMed:Cucurbitacin B reverses multidrug resistance by targeting CIP2A to reactivate protein phosphatase 2A in MCF-7/adriamycin cells.
PubMed:Cucurbitacin B inhibits breast cancer metastasis and angiogenesis through VEGF-mediated suppression of FAK/MMP-9 signaling axis.
PubMed:A biotransformation process for the production of cucurbitacin B from its glycoside using a selected Streptomyces sp.
PubMed:Cucurbitacin B inhibits the stemness and metastatic abilities of NSCLC via downregulation of canonical Wnt/β-catenin signaling axis.
PubMed:Cucurbitacin B Enhances the Anticancer Effect of Imatinib Mesylate Through Inhibition of MMP-2 Expression in MCF-7 and SW480 Tumor Cell Lines.
PubMed:Cytotoxic effects of natural and semisynthetic cucurbitacins on lung cancer cell line A549.
PubMed:[Rat intestine absorption kinetics study on cucurbitacin B-sodium deoxycholate/phospholipid mixed nanomicelles with in vitro everted gut sacs model].
PubMed:Cucurbitacins: A Systematic Review of the Phytochemistry and Anticancer Activity.
PubMed:Modulation of signal transduction pathways by natural compounds in cancer.
PubMed:Cucurbitacins attenuate microglial activation and protect from neuroinflammatory injury through Nrf2/ARE activation and STAT/NF-κB inhibition.
PubMed:Cucurbitacin B inhibits immunomodulatory function and the inflammatory response in macrophages.
PubMed:Synergistic effect of cucurbitacin B in combination with curcumin via enhancing apoptosis induction and reversing multidrug resistance in human hepatoma cells.
PubMed:A simple LC-MS method for determination of cyasterone in rat plasma: application to a pilot pharmacokinetic study.
PubMed:Synergistic Antiproliferative Effects of a New Cucurbitacin B Derivative and Chemotherapy Drugs on Lung Cancer Cell Line A549.
PubMed:Hepatoprotective and proapoptotic effect of Ecballium elaterium on CCl4-induced hepatotoxicity in rats.
PubMed:Approach for chemosensitization of cisplatin-resistant ovarian cancer by cucurbitacin B.
PubMed:Development and validation of a UPLC-MS/MS method for the determination of cucurbitacin B in rat plasma and application to a pharmacokinetic study.
PubMed:Treatment with cucurbitacin B alone and in combination with gefitinib induces cell cycle inhibition and apoptosis via EGFR and JAK/STAT pathway in human colorectal cancer cell lines.
PubMed:Cucurbitacin B induces DNA damage and autophagy mediated by reactive oxygen species (ROS) in MCF-7 breast cancer cells.
PubMed:Anticancer and anti-inflammatory activities of some dietary cucurbits.
PubMed:Effective mucoadhesive water-soluble polymers for the solidification transformation of phospholipid-bile salts-mixed micelles.
PubMed:The role of STAT3 in autophagy.
PubMed:Improve bile duct-targeted drug delivery and therapeutic efficacy for cholangiocarcinoma by cucurbitacin B loaded phospholipid complex modified with berberine hydrochloride.
PubMed:Cucurbitacin B Alters the Expression of Tumor-Related Genes by Epigenetic Modifications in NSCLC and Inhibits NNK-Induced Lung Tumorigenesis.
PubMed:Inhibitory effect of cucurbitacin B on imiquimod-induced skin inflammation.
PubMed:Corrigendum to "Cucurbitacin B Causes Increased Radiation Sensitivity of Human Breast Cancer Cells via G2/M Cell Cycle Arrest".
PubMed:In vitro and in vivo antitumor activity of a novel semisynthetic derivative of cucurbitacin B.
PubMed:Potential New Pharmacological Agents Derived From Medicinal Plants for the Treatment of Pancreatic Cancer.
PubMed:Cucurbitacin-B inhibits neuroblastoma cell proliferation through up-regulation of PTEN.
PubMed:[Preparation and characterization of cucurbitacin B sodium deoxycholate/phospholipid-mixed oral fast dissolving film and antitumor activity study].
PubMed:Cucurbitacin B inhibits proliferation and induces apoptosis via STAT3 pathway inhibition in A549 lung cancer cells.
PubMed:HER2 mediated de novo production of TGFβ leads to SNAIL driven epithelial-to-mesenchymal transition and metastasis of breast cancer.
PubMed:Molecular dynamics study of the diffusivity of a hydrophobic drug Cucurbitacin B in pseudo-poly(ethylene oxide-b-caprolactone) micelle environments.
PubMed:Cucurbitacin B induces DNA damage, G2/M phase arrest, and apoptosis mediated by reactive oxygen species (ROS) in leukemia K562 cells.
PubMed:Cucurbitacin B inhibits growth and induces apoptosis through the JAK2/STAT3 and MAPK pathways in SH‑SY5Y human neuroblastoma cells.
PubMed:Carbon and fullerene nanomaterials in plant system.
PubMed:Inhibition of Integrin-HER2 signaling by Cucurbitacin B leads to in vitro and in vivo breast tumor growth suppression.
PubMed:VASP activation via the Gα13/RhoA/PKA pathway mediates cucurbitacin-B-induced actin aggregation and cofilin-actin rod formation.
PubMed:Inactivation of ATP citrate lyase by Cucurbitacin B: A bioactive compound from cucumber, inhibits prostate cancer growth.
PubMed:Application of spray granulation for conversion of mixed phospholipid-bile salt micelles to dry powder form: influence of drug hydrophobicity on nanoparticle reagglomeration.
PubMed:Cucurbitacin B induced ATM-mediated DNA damage causes G2/M cell cycle arrest in a ROS-dependent manner.
PubMed:Mucoadhesive buccal films containing phospholipid-bile salts-mixed micelles as an effective carrier for Cucurbitacin B delivery.
PubMed:Cucurbitacin B inhibits the translational expression of hypoxia-inducible factor-1α.
PubMed:Cucurbitacin B and cucurbitacin I suppress adipocyte differentiation through inhibition of STAT3 signaling.
PubMed:The anti-melanoma efficiency of the intratumoral injection of cucurbitacin-loaded sustained-release carriers: a PLGA particle system.
PubMed:Formation of cofilin-actin rods following cucurbitacin-B-induced actin aggregation depends on Slingshot homolog 1-mediated cofilin hyperactivation.
PubMed:Nanobiotechnology can boost crop production and quality: first evidence from increased plant biomass, fruit yield and phytomedicine content in bitter melon (Momordica charantia).
PubMed:Steroid hormone signaling is involved in the age-dependent behavioral response to sex pheromone in the adult male moth Agrotis ipsilon.
PubMed:The effectiveness of cucurbitacin B in BRCA1 defective breast cancer cells.
PubMed:Cucurbitacin B and its rapidly emerging role in the management of systemic malignancies besides lung carcinomas.
PubMed:Cucurbitacin B potently suppresses non-small-cell lung cancer growth: identification of intracellular thiols as critical targets.
PubMed:The triterpenoid cucurbitacin B augments the antiproliferative activity of chemotherapy in human breast cancer.
PubMed:Cucurbitacin B inhibits human breast cancer cell proliferation through disruption of microtubule polymerization and nucleophosmin/B23 translocation.
PubMed:Preparation, characterization, cellular uptake and evaluation in vivo of solid lipid nanoparticles loaded with cucurbitacin B.
PubMed:Cucurbitacin B regulates immature myeloid cell differentiation and enhances antitumor immunity in patients with lung cancer.
PubMed:Cucurbitacin B induces cell cycle arrest, apoptosis and autophagy associated with G actin reduction and persistent activation of cofilin in Jurkat cells.
PubMed:Cucurbitacin B Causes Increased Radiation Sensitivity of Human Breast Cancer Cells via G2/M Cell Cycle Arrest.
PubMed:Synthesis and cytotoxic activity evaluation of dihydrocucurbitacin B and cucurbitacin B derivatives.
PubMed:Cucurbitacin induces autophagy through mitochondrial ROS production which counteracts to limit caspase-dependent apoptosis.
PubMed:The definition and significance of Cucurbitacin B a STAT3 inhibitors.
PubMed:Cucurbitacin B inhibits 12-O-tetradecanoylphorbol 13-acetate-induced invasion and migration of human hepatoma cells through inactivating mitogen-activated protein kinase and PI3K/Akt signal transduction pathways.
PubMed:Cucurbitacins-type triterpene with potent activity on mouse embryonic fibroblast from Cucumis prophetarum, cucurbitaceae.
PubMed:Inhibition of Wnt signaling by cucurbitacin B in breast cancer cells: reduction of Wnt-associated proteins and reduced translocation of galectin-3-mediated β-catenin to the nucleus.
PubMed:[Studies on chemical constituents in roots of Helicteres angustifolia].
PubMed:Cucurbitacin B induces rapid depletion of the G-actin pool through reactive oxygen species-dependent actin aggregation in melanoma cells.
PubMed:Histone deacetylase inhibitor valproic acid sensitizes B16F10 melanoma cells to cucurbitacin B treatment.
PubMed:Synergistic effect of low-dose cucurbitacin B and low-dose methotrexate for treatment of human osteosarcoma.
PubMed:Cucurbitacin B suppresses the transactivation activity of RelA/p65.
PubMed:Studies toward the total syntheses of cucurbitacins B and D.
PubMed:Cucurbitacin B inhibits growth, arrests the cell cycle, and potentiates antiproliferative efficacy of cisplatin in cutaneous squamous cell carcinoma cell lines.
PubMed:Cucurbitacin B, a novel in vivo potentiator of gemcitabine with low toxicity in the treatment of pancreatic cancer.
PubMed:Cucurbitacin B, a small molecule inhibitor of the Stat3 signaling pathway, enhances the chemosensitivity of laryngeal squamous cell carcinoma cells to cisplatin.
PubMed:An isoaurone and other constituents from Trichosanthes kirilowii seeds inhibit hypoxia-inducible factor-1 and nuclear factor-kappaB.
PubMed:Cucurbitacin E as a new inhibitor of cofilin phosphorylation in human leukemia U937 cells.
PubMed:Inhibition of pancreatic cancer cell growth by cucurbitacin B through modulation of signal transducer and activator of transcription 3 signaling.
PubMed:Cucurbitacin B induces apoptosis and S phase cell cycle arrest in BEL-7402 human hepatocellular carcinoma cells and is effective via oral administration.
PubMed:Galactosylated solid lipid nanoparticles with cucurbitacin B improves the liver targetability.
PubMed:Antiproliferative effects of cucurbitacin B in breast cancer cells: down-regulation of the c-Myc/hTERT/telomerase pathway and obstruction of the cell cycle.
PubMed:Cucurbitacin B induces G2 arrest and apoptosis via a reactive oxygen species-dependent mechanism in human colon adenocarcinoma SW480 cells.
PubMed:Prediction of the solubility of cucurbitacin drugs in self-associating poly(ethylene oxide)-b-poly(alpha-benzyl carboxylate epsilon-caprolactone) block copolymer with different tacticities using molecular dynamics simulation.
PubMed:Cucurbitacin B inhibits STAT3 and the Raf/MEK/ERK pathway in leukemia cell line K562.
PubMed:Roles of nonpolar and polar intermolecular interactions in the improvement of the drug loading capacity of PEO-b-PCL with increasing PCL content for two hydrophobic Cucurbitacin drugs.
PubMed:Cucurbitacin B induces apoptosis by inhibition of the JAK/STAT pathway and potentiates antiproliferative effects of gemcitabine on pancreatic cancer cells.
PubMed:Interaction of cucurbitacins with human serum albumin: Thermodynamic characteristics and influence on the binding of site specific ligands.
PubMed:Cucurbitane-type triterpenoids from the stems of Cucumis melo.
PubMed:Cytotoxic properties of root extract and fruit juice of Trichosanthes cucumerina.
PubMed:Cogniauxia podolaena: bioassay-guided fractionation of defoliated stems, isolation of active compounds, antiplasmodial activity and cytotoxicity.
PubMed:[Effects of cucurbitacin B on cell proliferation and apoptosis in Hep-2 cells].
PubMed:Cucurbitacin B has a potent antiproliferative effect on breast cancer cells in vitro and in vivo.
PubMed:Cucurbitacin B markedly inhibits growth and rapidly affects the cytoskeleton in glioblastoma multiforme.
PubMed:Targeted constitutive activation of signal transducer and activator of transcription 3 in human hepatocellular carcinoma cells by cucurbitacin B.
PubMed:Combined antitumor activity of cucurbitacin B and docetaxel in laryngeal cancer.
PubMed:Cucurbitacin B induces differentiation, cell cycle arrest, and actin cytoskeletal alterations in myeloid leukemia cells.
PubMed:Inhibitory effects of cucurbitacin B on laryngeal squamous cell carcinoma.
PubMed:Octanorcucurbitane and cucurbitane triterpenoids from the tubers of Hemsleya endecaphylla with HIV-1 inhibitory activity.
PubMed:Cucurbitacin glucosides: antioxidant and free-radical scavenging activities.
PubMed:Polymeric micelles for the solubilization and delivery of STAT3 inhibitor cucurbitacins in solid tumors.
PubMed:[Determination of the cucurbitacins from Cucubita pepo cv dayangua by HPLC].
PubMed:Small molecule inhibitors of Stat3 signaling pathway.
PubMed:Phytochemical and biological investigation of Begonia heracleifolia.
PubMed:Cucurbitane triterpenes from the fruiting bodies and cultivated mycelia of Leucopaxillus gentianeus.
PubMed:Studies on the cytotoxicity of cucurbitacins isolated from Cayaponia racemosa (Cucurbitaceae).
PubMed:Cucurbitacin B 2-sulfate and cucurbitacin glucosides from the root bark of Helicteres angustifolia.
PubMed:Growth inhibitory activity of cucurbitacin glucosides isolated from Citrullus colocynthis on human breast cancer cells.
PubMed:Cucurbitacin glucosides from Citrullus colocynthis.
PubMed:[Relationships of Aulacophora beetles feeding behavior with cucurbitacin types in host crops].
PubMed:Cucurbitacins and cucurbitane glycosides: structures and biological activities.
PubMed:[Studies on chemical constituents in bulbs of Bolbostemma paniculatum].
PubMed:Isolation of ani-hepatotoxic principle form the juice of Ecballium elaterium.
PubMed:Cucurbitane triterpenoids from Leucopaxillus gentianeus.
PubMed:Cytotoxic and anti-HIV principles from the rhizomes of Begonia nantoensis.
PubMed:Callus formation and cucurbitacin B accumulation in Ecballium elaterium callus cultures.
PubMed:The effect of manipulating ecdysteroid signaling on embryonic eye development in the locust Schistocerca americana.
PubMed:Morierinin: a new cytotoxic cucurbitacin from the leaves of Morierina montana Vieill.
PubMed:Antifeedant effects of proteinase inhibitors on feeding behaviors of adult western corn rootworm (Diabrotica virgifera virgifera).
PubMed:Bioactive constituents of the roots of Licania intrapetiolaris.
PubMed:Ecbalium elaterium (squirting cucumber)--remedy or poison?
PubMed:Novel cytotoxic diterpenes from Casearia arborea.
PubMed:Anti-inflammatory effects of the products from Wilbrandia ebracteata on carrageenan-induced pleurisy in mice.
PubMed:Cucurbitacins are insect steroid hormone antagonists acting at the ecdysteroid receptor.
PubMed:Anti-inflammatory and analgesic effects of cucurbitacins from Wilbrandia ebracteata.
PubMed:Identification of sensilla involved in taste mediation in adult western corn rootworm (Diabrotica virgifera virgifera LeConte).
PubMed:[Studies on the chemical constituents of Trichosanthes hupehensis C.Y. Cheng et Yueh].
PubMed:A new cucurbitacin profile forCucurbita andreana: A candidate for cucurbitacin tissue culture.
PubMed:New cucurbitacin glycosides from Picrorhiza kurrooa.
PubMed:[Studies on the constituents of "Trichosanthes root". IV. Constituents of roots of Trichosanthes multiloba Miq., Trichosanthes miyagii Hay. and Chinese crude drug "karo-kon"].
PubMed:[Studies on the constituents of trichosanthes root. III. Constituents of roots of Trichosanthes bracteata Voigt].
PubMed:[Studies on the constituents of trichosanthes root. I. Constituents of roots of Trichosanthes kirilowii Maxim. var. japonicum Kitam].
PubMed:Isolation of an anti-inflammatory principle from the fruit juice of Ecballium elaterium.
PubMed:Disposition and fate of cucurbitacin B in five species of diabroticites.
PubMed:Cucurbitacin B and isocucurbitacin B: cytotoxic components of Helicteres isora.
PubMed:Plant anticancer agents. XXX: Cucurbitacins from Ipomopsis aggregata (Polemoniaceae).
PubMed:Cucurbitacin B, the cytotoxic principle of Begonia tuberhybrida var. alba.
PubMed:Cucurbitacin B delta 23-reductase from Cucurbita maxima. I. Assay methods, isolation and purification.
PubMed:Cucurbitacin B delta 23-reductase from Cucurbita maxima. II. Cofactor requirements, enzyme kinetics, substrate specificity and other characteristics.
PubMed:A thin-layer and an improved paper-chromatographic method for the separation of cucurbitacin B. and 23, 24-dihydrocucurbitacin B.
PubMed:[THE DISTRIBUTION OF CUCURBITACINS AND CUCURBITACIN GLYCOSIDES IN THE GENUS IBERIS (CRUCIFERAE). ISOLATION OF CUCURBITACINS J AND K FROM IBERIS AMARA L. AND CUCURBITACIN B AND FROM IBERIS UMBELLATA L].
 
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