| PubMed:The alkaloids of Banisteriopsis caapi, the plant source of the Amazonian hallucinogen Ayahuasca, stimulate adult neurogenesis in vitro. |
| PubMed:Harmine is an inflammatory inhibitor through the suppression of NF-κB signaling. |
| PubMed:UVA Photoactivation of Harmol Enhances Its Antifungal Activity against the PhytopathogensPenicillium digitatumandBotrytis cinerea. |
| PubMed:Indole Alkaloids from Plants as Potential Leads for Antidepressant Drugs: A Mini Review. |
| PubMed:Parts-per-trillion detection of harmala alkaloids in Undaria pinnatifida algae by on-line solid phase extraction capillary electrophoresis mass spectrometry. |
| PubMed:Antifungal activity of β-carbolines on Penicillium digitatum and Botrytis cinerea. |
| PubMed:Antiviral activity of natural and synthetic β-carbolines against dengue virus. |
| PubMed:Quality criterion to optimize separations in capillary electrophoresis: Application to the analysis of harmala alkaloids. |
| PubMed:Interspecies metabolic diversity of harmaline and harmine in in vitro 11 mammalian liver microsomes. |
| PubMed:A rapid and simple method for the determination of psychoactive alkaloids by CE-UV: application to Peganum Harmala seed infusions. |
| PubMed:Functional Integrity of the Chimeric (Humanized) Mouse Liver: Enzyme Zonation, Physiologic Spaces, and Hepatic Enzymes and Transporters. |
| PubMed:The Potential of β Carbolin Alkaloids to Hinder Growth and Reverse Chloroquine Resistance in Plasmodium falciparum. |
| PubMed:Specific binding of [(18)F]fluoroethyl-harmol to monoamine oxidase A in rat brain cryostat sections, and compartmental analysis of binding in living brain. |
| PubMed:Interplay of metabolizing enzymes and transporter of xenobiotics. |
| PubMed:Determination of phytochemicals, antioxidant activity and total phenolic content in Andrographis paniculata using chromatographic methods. |
| PubMed:Fast determination of harmala alkaloids in edible algae by capillary electrophoresis mass spectrometry. |
| PubMed:Selective binding to monoamine oxidase A: in vitro and in vivo evaluation of (18)F-labeled β-carboline derivatives. |
| PubMed:Detection of monoamine oxidase a in brain of living rats with [18F]fluoroethyl-harmol PET. |
| PubMed:Inhibition of myeloperoxidase activity by the alkaloids of Peganum harmala L. (Zygophyllaceae). |
| PubMed:Simultaneous determination of harmine, harmaline and their metabolites harmol and harmalol in beagle dog plasma by UPLC-ESI-MS/MS and its application to a pharmacokinetic study. |
| PubMed:Harmol induces autophagy and subsequent apoptosis in U251MG human glioma cells through the downregulation of survivin. |
| PubMed:Simultaneous determination of alkaloids and flavonoids from aerial parts of Passiflora species and dietary supplements using UPLC-UV-MS and HPTLC. |
| PubMed:Metabolism and disposition of N,N-dimethyltryptamine and harmala alkaloids after oral administration of ayahuasca. |
| PubMed:Structure-activity relationship study of beta-carboline derivatives as haspin kinase inhibitors. |
| PubMed:Transcriptional and posttranslational inhibition of dioxin-mediated induction of CYP1A1 by harmine and harmol. |
| PubMed:The β-carboline alkaloid harmol induces cell death via autophagy but not apoptosis in human non-small cell lung cancer A549 cells. |
| PubMed:Inhibition of human cytochrome P450 enzymes 3A4 and 2D6 by β-carboline alkaloids, harmine derivatives. |
| PubMed:Mitochondrial dysfunction and biotransformation of β-carboline alkaloids, harmine and harmaline, on isolated rat hepatocytes. |
| PubMed:beta-Carboline alkaloids in Peganum harmala and inhibition of human monoamine oxidase (MAO). |
| PubMed:Banisteriopsis caapi, a unique combination of MAO inhibitory and antioxidative constituents for the activities relevant to neurodegenerative disorders and Parkinson's disease. |
| PubMed:Acetylcholinesterase inhibitive activity-guided isolation of two new alkaloids from seeds of Peganum nigellastrum Bunge by an in vitro TLC- bioautographic assay. |
| PubMed:Non-competitive androgen receptor inhibition in vitro and in vivo. |
| PubMed:Harmol induces apoptosis by caspase-8 activation independently of Fas/Fas ligand interaction in human lung carcinoma H596 cells. |
| PubMed:Antiplatelet activity of beta-carboline alkaloids from Perganum harmala: a possible mechanism through inhibiting PLCgamma2 phosphorylation. |
| PubMed:Apparent differences in mechanisms of harmol sulfate biliary excretion in mice and rats. |
| PubMed:Antioxidant properties of beta-carboline alkaloids are related to their antimutagenic and antigenotoxic activities. |
| PubMed:Effects of ayahuasca on psychometric measures of anxiety, panic-like and hopelessness in Santo Daime members. |
| PubMed:Evaluation of the role of multidrug resistance-associated protein (Mrp) 3 and Mrp4 in hepatic basolateral excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in Abcc3-/- and Abcc4-/- mice. |
| PubMed:The important role of Bcrp (Abcg2) in the biliary excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in mice. |
| PubMed:Effects of beta-carboline alkaloids on the object recognition task in mice. |
| PubMed:Effect of chlorine as substituent on the photochemistry and acid-base properties of beta-carboline alkaloids. |
| PubMed:Synthesis and antimycobacterial activity of some beta-carboline alkaloids. |
| PubMed:Sulfate conjugating and transport functions of MDCK distal tubular cells. |
| PubMed:HPLC method for the analysis of harmol, harmalol, harmine and harmaline in the seeds of Peganum harmala L. |
| PubMed:Determination of N,N-dimethyltryptamine and beta-carboline alkaloids in human plasma following oral administration of Ayahuasca. |
| PubMed:Transport of the sulfated, amidated bile acid, sulfolithocholyltaurine, into rat hepatocytes is mediated by Oatp1 and Oatp2. |
| PubMed:The modified dipeptide, enalapril, an angiotensin-converting enzyme inhibitor, is transported by the rat liver organic anion transport protein. |
| PubMed:Effects of molybdate on the sulfation of harmol and alpha-naphthol. |
| PubMed:beta-Carboline alkaloids as matrices for UV-matrix-assisted laser desorption/ionization time-of-flight mass spectrometry in positive and negative ion modes. Analysis of proteins of high molecular mass, and of cyclic and acyclic oligosaccharides. |
| PubMed:Effects of Ayahuasca on the human EEG. |
| PubMed:Genotoxic effects of structurally related beta-carboline alkaloids. |
| PubMed:Behavioural effects of Passiflora incarnata L. and its indole alkaloid and flavonoid derivatives and maltol in the mouse. |
| PubMed:Uptake of sulfate conjugates by isolated rat hepatocytes. |
| PubMed:Effect of erythrocyte binding on elimination of harmol by the isolated perfused rat liver. |
| PubMed:Simple beta-carboline alkaloids as nucleic acids fluorochromes. |
| PubMed:Methyl-beta-carbolinium analogs of MPP+ cause nigrostriatal toxicity after substantia nigra injections in rats. |
| PubMed:[Radioprotective effect of gamma-harmine and its carboline analogues]. |
| PubMed:2,6-Dichloro-4-nitrophenol (DCNP), an alternate-substrate inhibitor of phenolsulfotransferase. |
| PubMed:Inhibition of platelet aggregation and arachidonic acid metabolism by B-carboline alkaloids. |
| PubMed:Fasting increases the sensitivity of hepatic harmol glucuronidation to hypoxia. |
| PubMed:Effects of microsomal enzyme inducers upon UDP-glucuronic acid concentration and UDP-glucuronosyltransferase activity in the rat intestine and liver. |
| PubMed:Extractionless determination of diclofenac sodium in serum using reversed-phase high-performance liquid chromatography with fluorimetric detection. |
| PubMed:Malaria infection impairs glucuronidation and biliary excretion by the isolated perfused rat liver. |
| PubMed:Expression of a high-affinity form of UDP-glucuronosyltransferase in human foetal liver cells in culture on exposure to mercuric chloride. |
| PubMed:Selective inhibition of glucuronidation by 2,2,2-triphenylethyl-UDP in isolated rat hepatocytes: conjugation of harmol, 3,3',5-triiodothyronine, and N-hydroxy-2-acetylaminofluorene. |
| PubMed:Antioxidative properties of harmane and beta-carboline alkaloids. |
| PubMed:Sulphation of the flavonoids quercetin and catechin by rat liver. |
| PubMed:Intestinal biotransformation of harmol and 1-naphthol in the rat. Further evidence of dose-dependent phase-II conjugation in situ. |
| PubMed:Mercury-induced UDP-glucuronyltransferase (UDPGT) activity in mouse kidney. |
| PubMed:Fluorescence of harmol, harmalol and 2-hydroxycarbazole in concentrated hydroxide solutions. |
| PubMed:Upper motor neurone effects in sheep of some beta-carboline alkaloids identified in zygophyllaceous plants. |
| PubMed:UDP-glucuronyltransferase activity toward harmol in human liver and human fetal liver cells in culture. |
| PubMed:Effect of glutathione depletion on sulfate activation and sulfate ester formation in rats. |
| PubMed:Measurement of beta-carbolines by high-performance liquid chromatography with fluorescence detection. |
| PubMed:Beta-carbolines as antagonists of the discriminative stimulus effects of diazepam in rats. |
| PubMed:Synergistic effects of hypoxia and fasting on harmol elimination in the isolated perfused rat liver. |
| PubMed:Hypoxia impairs conjugation and elimination of harmol in the isolated perfused rat liver. |
| PubMed:Metabolism of the beta-carbolines, harmine and harmol, by liver microsomes from phenobarbitone- or 3-methylcholanthrene-treated mice. Identification and quantitation of two novel harmine metabolites. |
| PubMed:Inhibition of calcium channels by harmaline and other harmala alkaloids in vascular and intestinal smooth muscles. |
| PubMed:Mutagenicities of nitrosated carboline derivatives. |
| PubMed:High-performance liquid chromatographic analysis of harmol and its conjugated metabolites after enzyme hydrolysis in biological fluids. |
| PubMed:Kinetics of sulfation in the rat in vivo and in the perfused rat liver. |
| PubMed:Heterogeneous distribution of the conjugation activity of acetaminophen and p-nitrophenol in isolated rat liver cells. |
| PubMed:Food-borne amines and amides as potential precursors of endogenous carcinogens. |
| PubMed:Alteration of transit time and direction of flow to probe the heterogeneous distribution of conjugating activities for harmol in the perfused rat liver preparation. |
| PubMed:Secretion of the organic anion harmol sulfate from liver into blood. Evidence for a carrier-mediated mechanism. |
| PubMed:Extrahepatic sulfation and glucuronidation in the rat in vivo. Determination of the hepatic extraction ratio of harmol and the extrahepatic contribution to harmol conjugation. |
| PubMed:Heterogeneous distribution of conjugation activities of harmol in isolated rat liver cells. |
| PubMed:D-cysteine as a selective precursor for inorganic sulfate in the rat in vivo. Effect of D-cysteine on the sulfation of harmol. |
| PubMed:Factors influencing sulfation in isolated rat hepatocytes. |
| PubMed:Effects of betacarbolines on the automaticity of the guinea pig sinus node. |
| PubMed:Comparison of beta-adrenoceptor antagonists as modulators of drug metabolism: effect of lipophilicity on microsomal phase I and II reactions. |
| PubMed:Metabolism of harmol and transport of harmol conjugates in isolated rat hepatocytes. |
| PubMed:Use of pentachlorophenol as long-term inhibitor of sulfation of phenols and hydroxamic acids in the rat in vivo. |
| PubMed:Ionization processes of some harmala alkaloids. |
| PubMed:Normal and retrograde perfusion to probe the zonal distribution of sulfation and glucuronidation activities of harmol in the perfused rat liver preparation. |
| PubMed:Differential effects of phenobarbitone and 3-methylcholanthrene induction on the hepatic microsomal metabolism of the beta-carbolines harmine and harmol. |
| PubMed:The dependence of the rate of sulphate conjugation on the plasma concentration of inorganic sulphate in the rat in vivo. |
| PubMed:Importance of extrahepatic sulphate conjugation. |
| PubMed:Kinetics of sulfation and glucuronidation of harmol in the perfused rat liver preparation. Disappearance of aberrances in glucuronidation kinetics by inhibition of sulfation. |
| PubMed:Cholestatic effect of harmol glucuronide in the rat. Prevention of harmol-induced cholestasis by increased formation of harmol sulfate. |
| PubMed:The effect of fasting on sulfation and glucuronidation in the rat in vivo. |
| PubMed:Selective inhibition of sulfate conjugation in the rat: pharmacokinetics and characterization of the inhibitory effect of 2,6-dichloro-4-nitrophenol. |
| PubMed:Elevation of conjugation capacity in isolated hepatocytes from BHA-treated mice. |
| PubMed:Sulphate and glucuronic acid conjugation of harmol in human fetal and adult liver tissue. |
| PubMed:Aberrant Pharmacokinetics of harmol in the perfused rat liver preparation: sulfate and glucuronide conjugations. |
| PubMed:Dose-dependent shifts in the sulfation and glucuronidation of phenolic compounds in the rat in vivo and in isolated hepatocytes. The role of saturation of phenolsulfotransferase. |
| PubMed:Effect of calcium ions on ethanol oxidation and drug glucuronidation in isolated hepatocytes. |
| PubMed:Inhibition of sulfation of phenols in vivo by 2,6-dichloro-4-nitrophenol: selectivity of its action in relation to other conjugations in the rat in vivo. |
| PubMed:Xenobiotic metabolism by isolated rat small intestinal cells. |
| PubMed:Assay of adenosine 3'-phosphate 5'-sulphatophosphate in hepatic tissues. |
| PubMed:Biliary and urinary excretion of drug conjugates: effect of diuresis and choleresis on excretion of harmol sulphate and harmol glucuronide in the rat. |
| PubMed:Metabolism of inorganic sulphate in the isolated perfused rat liver. Effect of sulphate concentration on the rate of sulphation by phenol sulphotransferase. |
| PubMed:Uptake of glucuronides into isolated hepatocytes and their effects on glucuronide and sulphate conjugation. |
| PubMed:The availability of inorganic sulphate in blood for sulphate conjugation of drugs in rat liver in vivo. (35S)Sulphate incorporation into harmol sulphate. |
| PubMed:Phenol sulphotransferase and uridine diphosphate glucuronyltransferase from rat liver in vivo and vitro. 2,6-Dichloro-4-nitrophenol as selective inhibitor of sulphation. |
| PubMed:Observations on the accessibility of acceptor substrates to the active centre of UDP-glucuronosyltransferase in vitro. |
| PubMed:Species and phenobarbitone-induced differences in the kinetic constants of liver microsomal harmine O-demethylation. |
| PubMed:UDP glucuronyltransferase and phenolsulfotransferase from rat liver in vivo and in vitro--IV. Species differences in harmol conjugation and elimination in bile and urine in vivo. |
| PubMed:UDP glucuronyltransferase and phenolsulfotransferase from rat liver in vivo and in vitro. III. The effect of phenolphthalein and its sulfate and glucuronide conjugate on conjugation and biliary excretion of harmol. |
| PubMed:UDP glucuronyltransferase and phenolsulfotransferase from rat liver in vivo and in vitro. Characterization of conjugation and biliary excretion of harmol in vivo and in the perfused liver. |
| PubMed:UDP glucuronyltransferase and phenolsulfotransferase in vivo and in vitro. Conjugation of harmol and harmalol. |
| PubMed:Glucuronidation of 3-O-methylnoradrenaline, harmalol and some related compounds. |
| PubMed:[On 2 pharmacological properties, not yet known, of harmol]. |
3D/inchi