EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

licoricidin

Supplier Sponsors

CAS Number: 30508-27-1Picture of molecule3D/inchi
FDA UNII: 929XTD20VK
Nikkaji Web:J885.811J
XlogP3-AA:6.40 (est)
Molecular Weight:424.53704000
Formula:C26 H32 O5
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 0.001253 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Licoricidin >98%
Odor: characteristic
Use: Licoricidin is a natural flavonoid compound found in several plants.
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for licoricidin usage levels up to:
 not for fragrance use.
 
Recommendation for licoricidin flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :480865
National Institute of Allergy and Infectious Diseases:Data
4-[(3R)-7-hydroxy-5-methoxy-6-(3-methylbut-2-enyl)-3,4-dihydro-2H-chromen-3-yl]-2-(3-methylbut-2-enyl)benzene-1,3-diol
Chemidplus:0030508271
 
References:
  4-[(3R)-7-hydroxy-5-methoxy-6-(3-methylbut-2-enyl)-3,4-dihydro-2H-chromen-3-yl]-2-(3-methylbut-2-enyl)benzene-1,3-diol
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):480865
Pubchem (cas):30508-27-1
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C16986
HMDB (The Human Metabolome Database):HMDB34183
FooDB:FDB012476
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 glycyrrhiza glabra root
Search Trop Picture
 glycyrrhiza uralensis root
Search Trop Picture
 
Synonyms:
4-((R)-7-hydroxy-5-methoxy-6-(3-methyl-but-2-enyl)-1-benzopyran-3-yl)-2-((E)-3-methyl-but-2-enyl)-benzene-1,3-diol
4-[(3R)-7-hydroxy-5-methoxy-6-(3-methylbut-2-enyl)-3,4-dihydro-2H-chromen-3-yl]-2-(3-methylbut-2-enyl)benzene-1,3-diol
 

Articles:

PubMed:Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents.
PubMed:Licoricidin inhibits the growth of SW480 human colorectal adenocarcinoma cells in vitro and in vivo by inducing cycle arrest, apoptosis and autophagy.
PubMed:Isolation and characterization of antimutagenic components ofGlycyrrhiza asperaagainstN-methyl-N-nitrosourea.
PubMed:Identification and Chemical Standardization of Licorice Raw Materials and Dietary Supplements Using UHPLC-MS/MS.
PubMed:Anti-Cancer Effect of Quercetin in Xenograft Models with EBV-Associated Human Gastric Carcinoma.
PubMed:Licoricidin, an isoflavonoid isolated from Glycyrrhiza uralensis Fisher, prevents UVA-induced photoaging of human dermal fibroblasts.
PubMed:Licoricidin, an Active Compound in the Hexane/Ethanol Extract of Glycyrrhiza uralensis, Inhibits Lung Metastasis of 4T1 Murine Mammary Carcinoma Cells.
PubMed:Metabolites identification of bioactive licorice compounds in rats.
PubMed:Prenylated polyphenolic compounds from Glycyrrhiza iconica and their antimicrobial and antioxidant activities.
PubMed:Structures of new phenolics isolated from licorice, and the effectiveness of licorice phenolics on vancomycin-resistant Enterococci.
PubMed:Pyrano-isoflavans from Glycyrrhiza uralensis with antibacterial activity against Streptococcus mutans and Porphyromonas gingivalis.
PubMed:Reduction of bacterial volatile sulfur compound production by licoricidin and licorisoflavan A from licorice.
PubMed:Flavonoids, a ubiquitous dietary phenolic subclass, exert extensive in vitro anti-invasive and in vivo anti-metastatic activities.
PubMed:Isoflavonoids and coumarins from Glycyrrhiza uralensis: antibacterial activity against oral pathogens and conversion of isoflavans into isoflavan-quinones during purification.
PubMed:Licorice and its potential beneficial effects in common oro-dental diseases.
PubMed:Modulation of matrix metalloproteinase and cytokine production by licorice isolates licoricidin and licorisoflavan A: potential therapeutic approach for periodontitis.
PubMed:Hexane-ethanol extract of Glycyrrhiza uralensis containing licoricidin inhibits the metastatic capacity of DU145 human prostate cancer cells.
PubMed:Effects of tannins and related polyphenols on methicillin-resistant Staphylococcus aureus.
PubMed:Antinephritis and radical scavenging activity of prenylflavonoids.
PubMed:Anti-Helicobacter pylori flavonoids from licorice extract.
PubMed:Antibacterial compounds of licorice against upper airway respiratory tract pathogens.
PubMed:Phenolic constituents of licorice. VIII. Structures of glicophenone and glicoisoflavanone, and effects of licorice phenolics on methicillin-resistant Staphylococcus aureus.
PubMed:Inhibition of lysoPAF acetyltransferase activity by components of licorice root.
PubMed:Inhibition of adenosine 3',5'-cyclic monophosphate phosphodiesterase by flavonoids from licorice roots and 4-arylcoumarins.
PubMed:The chemical studies on the oriental plant drugs. XIX. Some new constituents of licorice root. 1. The structure of licoricidin.
 
Notes:
None found
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