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ganoderic acid DM

Supplier Sponsors

CAS Number: 173075-45-1Picture of molecule3D/inchi
FDA UNII: Search
Nikkaji Web:J2.046.033D
MDL:MFCD04039843
XlogP3-AA:6.40 (est)
Molecular Weight:468.67748000
Formula:C30 H44 O4
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
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PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 0.0004257 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Ganoderic acid DM 97.5%
Odor: characteristic
Use: Ganoderic acid DM is a natural compound isolated from the fruit body of Ganode
Carbosynth
For experimental / research use only.
Ganoderic acid DM
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for ganoderic acid DM usage levels up to:
 not for fragrance use.
 
Recommendation for ganoderic acid DM flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :11784642
National Institute of Allergy and Infectious Diseases:Data
(E,6R)-2-methyl-6-[(5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-3,7-dioxo-2,5,6,11,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]hept-2-enoic acid
 
References:
 (E,6R)-2-methyl-6-[(5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-3,7-dioxo-2,5,6,11,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]hept-2-enoic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):11784642
Pubchem (cas):173075-45-1
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):HMDB32837
FooDB:FDB010814
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 ganoderma lucida
Search PMC Picture
 
Synonyms:
(E,6R)-2-methyl-6-[(5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-3,7-dioxo-2,5,6,11,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]hept-2-enoic acid
 

Articles:

PubMed:Anticancer Activity of Ganoderic Acid DM: Current Status and Future Perspective.
PubMed:Novel binding patterns between ganoderic acids and neuraminidase: Insights from docking, molecular dynamics and MM/PBSA studies.
PubMed:Distinct Responses of Cytotoxic Ganoderma lucidum Triterpenoids in Human Carcinoma Cells.
PubMed:A novel component from citrus, ginger, and mushroom family exhibits antitumor activity on human meningioma cells through suppressing the Wnt/β-catenin signaling pathway.
PubMed:Target proteins of ganoderic acid DM provides clues to various pharmacological mechanisms.
PubMed:A possible cross-talk between autophagy and apoptosis in generating an immune response in melanoma.
PubMed:Ganoderic acid DM, a natural triterpenoid, induces DNA damage, G1 cell cycle arrest and apoptosis in human breast cancer cells.
PubMed:Macromolecular and small-molecule modulation of intracellular Aβ42 aggregation and associated toxicity.
PubMed:Ganoderic Acid DM: An Alternative Agent for the Treatment of Advanced Prostate Cancer.
PubMed:Ganoderic acid DM: anti-androgenic osteoclastogenesis inhibitor.
PubMed:Regulation of osteoclastogenesis by ganoderic acid DM isolated from Ganoderma lucidum.
PubMed:Quality evaluation of Ganoderma through simultaneous determination of nine triterpenes and sterols using pressurized liquid extraction and high performance liquid chromatography.
PubMed:5alpha-reductase inhibitory effect of triterpenoids isolated from Ganoderma lucidum.
PubMed:[Studies on the ganoderic acid, a new constituents from the fruiting body of Ganoderma lucidum (Fr.) Karst].
 
Notes:
None found
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