EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

dihydrocurcumin
letestuianin B

Supplier Sponsors

CAS Number: 76474-56-1Picture of molecule3D/inchi
FDA UNII: 4YU9OA673J
XlogP3-AA:3.00 (est)
Molecular Weight:370.40154000
Formula:C21 H22 O6
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 8.397 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Dihydrocurcumin 98%
BOC Sciences
For experimental / research use only.
Dihydrocurcumin >98%
Odor: characteristic
Use: Dihydrocurcumin can be found in the rhizome of Curcuma longa L. Curcumin was first biotransformed to Dihydrocurcumin and tetrahydrocurcumin and that these compounds subsequently were converted to monoglucuronide conjugates.
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for dihydrocurcumin usage levels up to:
 not for fragrance use.
 
Recommendation for dihydrocurcumin flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :10429233
National Institute of Allergy and Infectious Diseases:Data
(E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hept-1-ene-3,5-dione
Chemidplus:0076474561
 
References:
 (E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hept-1-ene-3,5-dione
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):10429233
Pubchem (cas):76474-56-1
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
HMDB (The Human Metabolome Database):HMDB31552
FooDB:FDB008164
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 curcuma longa rhizome
Search Trop Picture
 
Synonyms:
4,6-heptadien-3-one, 5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)-, (4Z,6E)-
(1E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hept-1-ene-3,5-dione
 letestuianin B
 

Articles:

PubMed:Degradation of curcuminoids by in vitro pure culture fermentation.
PubMed:Formation of tetrahydrocurcumin by reduction of curcumin with cultured plant cells of Marchantia polymorpha.
PubMed:Discovery of the curcumin metabolic pathway involving a unique enzyme in an intestinal microorganism.
PubMed:Isolation of dihydrocurcuminoids from cell clumps and their distribution in various parts of turmeric (Curcuma longa).
PubMed:Anti-allergic principles from Thai zedoary: structural requirements of curcuminoids for inhibition of degranulation and effect on the release of TNF-alpha and IL-4 in RBL-2H3 cells.
PubMed:Suppression of protein kinase C and nuclear oncogene expression as possible action mechanisms of cancer chemoprevention by Curcumin.
PubMed:Mechanisms of cancer chemoprevention by curcumin.
PubMed:Recent studies on the biofunctions and biotransformations of curcumin.
PubMed:Biotransformation of curcumin through reduction and glucuronidation in mice.
 
Notes:
None found
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