sarmentosin, 71933-54-5

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CODE182202 CODE182202
Product(s):
71933-54-5 Sarmentosin 0.97
Sarmentosin isolated from the herb of Sedum sarmetosum Bunge. It shows a good effect in lowering serum glutamate-pyruvate transaminase and lowering the SGPT level of patients suffering from chronic viral hepatitis. Sarmentosin shows a suppressive effect on cell-mediated immune responses in mice.

CAS Number:	71933-54-5	3D/inchi
FDA UNII:	Search
Nikkaji Web:	J589.931A
XlogP3:	-3.10 (est)
Molecular Weight:	275.25789000
Formula:	C11 H17 N O7
NMR Predictor:	Predict (works with chrome, Edge or firefox)

Category:natural substances and extractives

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
Google Books:	Search
Google Scholar: with word "volatile"	Search
Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search

Physical Properties:

Assay:	95.00 to 100.00
Food Chemicals Codex Listed:	No
Soluble in:
	water, 1e+006 mg/L @ 25 °C (est)

Organoleptic Properties:

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

None found

Suppliers:

BOC Sciences

For experimental / research use only.

Sarmentosin 0.97

Odor: characteristic

Use: Sarmentosin isolated from the herb of Sedum sarmetosum Bunge. It shows a good effect in lowering serum glutamate-pyruvate transaminase and lowering the SGPT level of patients suffering from chronic viral hepatitis. Sarmentosin shows a suppressive effect on cell-mediated immune responses in mice.

Safety Information:


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
natural substances and extractives
Recommendation for sarmentosin usage levels up to:
	not for fragrance use.

Recommendation for sarmentosin flavor usage levels up to:
	not for flavor use.

Safety References:

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :6438710

National Institute of Allergy and Infectious Diseases:Data

(Z)-2-(hydroxymethyl)-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybut-2-enenitrile

Chemidplus:0071933545

References:

	(Z)-2-(hydroxymethyl)-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybut-2-enenitrile
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	6438710
Pubchem (cas):	71933-54-5
Pherobase:	View

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
KEGG (GenomeNet):	C08340
HMDB (The Human Metabolome Database):	HMDB30697
FooDB:	FDB002618
VCF-Online:	VCF Volatile Compounds in Food
ChemSpider:	View

Potential Blenders and core components note

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):note

	ribes nigrum Search Trop Picture
	sedum sarmentosum Search Trop Picture

Synonyms:

2-	butenenitrile, 4-(beta-D-glucopyranosyloxy)-2-(hydroxymethyl)-, (E)-
(Z)-2-(	hydroxymethyl)-4-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybut-2-enenitrile

Articles:

PubMed:Occurrence of sarmentosin and other hydroxynitrile glucosides in Parnassius (papilionidae) butterflies and their food plants.

PubMed:Hepatoprotective effects of Sedum sarmentosum on D-galactosamine/lipopolysaccharide-induced murine fulminant hepatic failure.

PubMed:Diversification of an ancient theme: hydroxynitrile glucosides.

PubMed:Synthesis of aglycon analogues of sarmentosin and their bioactivity of lymphocyte proliferation.

PubMed:Prolyl endopeptidase inhibitors from the underground part of Rhodiola sacra S. H. Fu.

PubMed:[Sarmentosin-Epoxid, eine neue cyanogene Verbindung aus Sedum cepaea.].

Notes:

None found