EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

withanolide B
lycium substance B

Supplier Sponsors

CAS Number: 56973-41-2Picture of molecule3D/inchi
FDA UNII: 9YU877VU8K
Nikkaji Web:J1.712.385H
MDL:MFCD19053156
XlogP3-AA:4.70 (est)
Molecular Weight:454.60686000
Formula:C28 H38 O5
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 1.749 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
BOC Sciences
For experimental / research use only.
Withanolide B ≥95%
Odor: characteristic
Use: Withanolide B is a withanolide that has been found in W. somnifera. Unlike withanolide A, it does not increase glucose uptake i
Sigma-Aldrich
For experimental / research use only.
Withanolide B analytical standard
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for withanolide B usage levels up to:
 not for fragrance use.
 
Recommendation for withanolide B flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :14236711
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
Chemidplus:0056973412
 
References:
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):14236711
Pubchem (cas):56973-41-2
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):HMDB30020
FooDB:FDB001313
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 lycium chinense leaf
Search Trop Picture
 
Synonyms:
 ergosta-2,24-dien-26-oic acid, 6,7-epoxy-5,22-dihydroxy-1-oxo-, delta-lactone, (5alpha,6alpha,7alpha,22R)-
(5alpha,6alpha,7alpha,22R)-5-hydroxy-6,7:22,26-diepoxyergosta-2,24-diene-1,26-dione
 lycium substance B
 

Articles:

PubMed:Determination of Withanolides inWithania somniferaby Liquid Chromatography: Single-Laboratory Validation, First Action 2015.17.
PubMed:Exploring neuroprotective potential of Withania somnifera phytochemicals by inhibition of GluN2B-containing NMDA receptors: An in silico study.
PubMed:Evaluation of the bioavailability of major withanolides of Withania somnifera using an in vitro absorption model system.
PubMed:Sonication, Vacuum Infiltration and Thiol Compounds Enhance the Agrobacterium-Mediated Transformation Frequency of Withania somnifera (L.) Dunal.
PubMed:Effect of carbon and nitrogen sources on in vitro flower and fruit formation and withanolides production in Withania somnifera (L.) Dunal.
PubMed:Lycium barbarum polysaccharide improves traumatic cognition via reversing imbalance of apoptosis/regeneration in hippocampal neurons after stress.
PubMed:Enhanced biosynthesis of withanolides by elicitation and precursor feeding in cell suspension culture of Withania somnifera (L.) Dunal in shake-flask culture and bioreactor.
PubMed:Withania somnifera attenuates acid production, acid tolerance and extra-cellular polysaccharide formation of Streptococcus mutans biofilms.
PubMed:A promising approach on biomass accumulation and withanolides production in cell suspension culture of Withania somnifera (L.) Dunal.
PubMed:Optimization of elicitation conditions with methyl jasmonate and salicylic acid to improve the productivity of withanolides in the adventitious root culture of Withania somnifera (L.) Dunal.
PubMed:New withanolides from Mandragora officinarum: first report of withanolides from the Genus Mandragora.
PubMed:Withanolide Z, a new chlorinated withanolide from Withania somnifera.
PubMed:Analysis of withanolides in root and leaf of Withania somnifera by HPLC with photodiode array and evaporative light scattering detection.
 
Notes:
None found
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