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liquiritin
liquiritoside

Supplier Sponsors

CAS Number: 551-15-5Picture of molecule3D/inchi
Other(deleted CASRN):100483-53-2
FDA UNII: T0O79T74CD
Nikkaji Web:J22.605J
XlogP3-AA:0.40 (est)
Molecular Weight:418.39914000
Formula:C21 H22 O9
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 4899 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Liquiritin 98%
BOC Sciences
For experimental / research use only.
Liquiritin
ExtraSynthese
For experimental / research use only.
Liquiritin
Santa Cruz Biotechnology
For experimental / research use only.
Liquiritin ≥97%
Sigma-Aldrich: Sigma
For experimental / research use only.
Liquiritin from Glycyrrhizae root (licorice root), ≥98% (HPLC)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for liquiritin usage levels up to:
 not for fragrance use.
 
Recommendation for liquiritin flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :503737
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
(2S)-7-hydroxy-2-[4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-2,3-dihydrochromen-4-one
Chemidplus:0000551155
 
References:
 (2S)-7-hydroxy-2-[4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-2,3-dihydrochromen-4-one
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):503737
Pubchem (cas):551-15-5
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):C16989
HMDB (The Human Metabolome Database):HMDB29520
FooDB:FDB000656
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 glycyrrhiza glabra
Search Trop Picture
 glycyrrhiza uralensis
Search Trop Picture
 
Synonyms:
4H-1-benzopyran-4-one, 2-(4-(beta-D-glucopyranosyloxy)phenyl)-2,3-dihydro-7-hydroxy-, (S)-
(S)-2-(4-(beta-D-glucopyranosyloxy)phenyl)-2,3-dihydro-7-hydroxy-4H-1-benzopyran-4-one
(2S)-7-hydroxy-2-[4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-2,3-dihydrochromen-4-one
 likviritin
 liquiritoside
 

Articles:

PubMed:Protective effect and molecular mechanism of liquiritin on oxybuprocaine-induced apoptosis of human corneal endothelial cells.
PubMed:Intestinal absorption differences of major bioactive compounds of Gegenqinlian Decoction between normal and bacterial diarrheal mini-pigs in vitro and in situ.
PubMed:Paljung-San, a traditional herbal medicine, attenuates benign prostatic hyperplasia in vitro and in vivo.
PubMed:Arbuscular mycorrhiza facilitates the accumulation of glycyrrhizin and liquiritin in Glycyrrhiza uralensis under drought stress.
PubMed:The effect of ethanol extract of Glycyrrhiza uralensis on the voltage-gated sodium channel subtype 1.4.
PubMed:Pharmacokinetic comparisons of six components from raw and vinegar-processed Daphne genkwa aqueous extracts following oral administration in rats by employing UHPLC-MS/MS approaches.
PubMed:A Comparative Pharmacokinetic Study by UHPLC-MS/MS of Main Active Compounds after Oral Administration of Zushima-Gancao Extract in Normal and Adjuvant-Induced Arthritis Rats.
PubMed:Simultaneous quantification of multiple components in rat plasma by UPLC-MS/MS and pharmacokinetic study after oral administration of Huangqi decoction.
PubMed:[Study on correlation between color and effective components contents of Glycyrrhiza uralensis].
PubMed:Antitussive and expectorant activities of licorice and its major compounds.
PubMed:Pharmacokinetic Assessments of Liquiritin, Protocatechuic Aldehyde and Rosmarinic Acid in Rat Plasma by UPLC-MS-MS After Administration of ZibuPiyin Recipe.
PubMed:Multi-parameters monitoring during traditional Chinese medicine concentration process with near infrared spectroscopy and chemometrics.
PubMed:Simultaneous Determination of Seven Components in Rat Plasma by the UPLC-MS/MS Method and Application of Pharmacokinetic Studies to SimiaoYong'an Decoction.
PubMed:[Absorption enhancing effects and safety of PAMAM dendrimers on liquiritin].
PubMed:Liquiritin induces apoptosis and autophagy in cisplatin (DDP)-resistant gastric cancer cells in vitro and xenograft nude mice in vivo.
PubMed:Simultaneous Quantification of Eight Marker Compounds in Yongdamsagan-Tang Using a High-Performance Liquid Chromatography Equipped with Photodiode Array Detector.
PubMed:[Research on Glycyrrhizeae Radix standard decoction].
PubMed:Neuroprotective effect of liquiritin as an antioxidant via an increase in glucose-6-phosphate dehydrogenase expression on B65 neuroblastoma cells.
PubMed:Intestinal Absorption of Triterpenoids and Flavonoids from Glycyrrhizae radix et rhizoma in the Human Caco-2 Monolayer Cell Model.
PubMed:[Comparative identification studies on wild and cultivated Glycyrrhiza uralensis produced Ningxia based on index components and near-infrared spectroscopy].
PubMed:Influence of Jiegeng on Pharmacokinetic Properties of Flavonoids and Saponins in Gancao.
PubMed:[Rapid monitoring five components of ethanol precipitation process of Shenzhiling oral solution using near infrared spectroscopy].
PubMed:Spasmolytic Mechanism of Aqueous Licorice Extract on Oxytocin-Induced Uterine Contraction through Inhibiting the Phosphorylation of Heat Shock Protein 27.
PubMed:Neuroprotective effect of liquiritin against neuropathic pain induced by chronic constriction injury of the sciatic nerve in mice.
PubMed:[Application of relative quality constant in grades evaluation of Glycyrrizae Radix et Rhizome pieces].
PubMed:Simultaneous quantitation of six aconitum alkaloids and three flavonoids in the herb couple of radix aconiti lateralis-radix glycyrrhizae (Fuzi-Gancao) by UHPLC-ESI-MS/MS.
PubMed:Simultaneous Determination of 11 Compounds in Gualou Guizhi Granule and Pharmacokinetics Study by UPLC-MS/MS.
PubMed:Comparatively evaluating the pharmacokinetic of fifteen constituents in normal and blood deficiency rats after oral administration of Xin-Sheng-Hua Granule by UPLC-MS/MS.
PubMed:Combining TRAIL and liquiritin exerts synergistic effects against human gastric cancer cells and xenograft in nude mice through potentiating apoptosis and ROS generation.
PubMed:Chinese herbal medicine for Alzheimer's disease: Clinical evidence and possible mechanism of neurogenesis.
PubMed:REDUCING TOXICITY AND INCREASING EFFICIENCY: ACONITINE WITH LIQUIRITIN AND GLYCYRRHETINIC ACID REGULATE CALCIUM REGULATORY PROTEINS IN RAT MYOCARDIAL CELL.
PubMed:Simultaneous Determination of 8 Compounds in Gancao-Ganjiang-Tang by HPLC-DAD and Analysis of the Relations between Compatibility, Dosage, and Contents of Medicines.
PubMed:Pharmacokinetics study of Erhuang decoction extracts in rats by HPLC-MS/MS.
PubMed:Liquiritin (LT) exhibits suppressive effects against the growth of human cervical cancer cells through activating Caspase-3 in vitro and xenograft mice in vivo.
PubMed:The Mealiness and Quality of Herbal Medicine: Licorice for Example.
PubMed:Optimization of a Decoction Process for an Herbal Formula Using a Response Surface Methodology.
PubMed:Simultaneous determination of nine bioactive compounds in Yijin-tang via high-performance liquid chromatography and liquid chromatography-electrospray ionization-mass spectrometry.
PubMed:An LC-MS/MS method for determination of bioactive components of liquorice and Semen Strychni in rat plasma: Application to a pharmacokinetics study.
PubMed:Identification of bioactive compounds in Shaoyao-Gancao decoction using β2-adrenoceptor affinity chromatography.
PubMed:Identification of NF-κB as Determinant of Posttraumatic Stress Disorder and Its Inhibition by the Chinese Herbal RemedyFree and Easy Wanderer.
PubMed:Paeoniflorin and liquiritin, two major constituents in Chinese herbal formulas used to treat hyperprolactinemia-associated disorders, inhibits prolactin secretion in prolactinoma cells by different mechanisms.
PubMed:Simultaneous quantitative determination of 13 active components in the traditional Chinese medicinal preparation Suanzaoren oral liquid by HPLC coupled with diode array detection and evaporative light scattering detection.
PubMed:Components of Goutengsan in Rat Plasma by Microdialysis Sampling and Its Protection on Aβ1-42-Induced PC12 Cells Injury.
PubMed:Simultaneous determination of multiple active components in rat plasma using ultra-fast liquid chromatography with tandem mass spectrometry and application to a comparative pharmacokinetic study after oral administration of Suan-Zao-Ren decoction and Suan-Zao-Ren granule.
PubMed:Antibacterial and Antiadhesive Activities of Extracts from Edible Plants against Soft Drink Spoilage by Asaia spp.
PubMed:Pharmacokinetic interaction of aconitine, liquiritin and 6-gingerol in a traditional Chinese herbal formula, Sini Decoction.
PubMed:Development of a UPLC-TQ/MS Approach for the Determination of Eleven Bioactive Components in Haizao Yuhu Decoction Plus-Minus Haizao and Gancao Drug Combination after Oral Administration in a Rat Model of Hypothyroidism.
PubMed:Control of stress-induced depressive disorders by So-ochim-tang-gamibang, a Korean herbal medicine.
PubMed:Simultaneous determination of glycyrrhizin and liquiritin in licorice roots and Kampo medicines by combination enzyme-linked immunosorbent assay using anti-glycyrrhizin and anti-liquiritin monoclonal antibodies.
PubMed:The protective role of liquiritin in high fructose-induced myocardial fibrosis via inhibiting NF-κB and MAPK signaling pathway.
PubMed:Identification and Chemical Standardization of Licorice Raw Materials and Dietary Supplements Using UHPLC-MS/MS.
PubMed:Simultaneous Determinations of Eleven Bioactive Components in Suanzaoren Decoction Granules by High-Performance Liquid Chromatography and Its Application to the Quality Control in Productive Processes.
PubMed:Anti-Cancer Effect of Quercetin in Xenograft Models with EBV-Associated Human Gastric Carcinoma.
PubMed:Gu-Ben-Fang-Xiao decoction attenuates sustained airway inflammation by suppressing ER stress response in a murine asthma remission model of respiratory syncytial virus infection.
PubMed:Neuroprotective effects of liquiritin on cognitive deficits induced by soluble amyloid-β1-42oligomers injected into the hippocampus.
PubMed:Chemomics-Integrated Proteomics Analysis of Jie-Geng-Tang to Ameliorate Lipopolysaccharide-Induced Acute Lung Injury in Mice.
PubMed:Pharmacokinetic Effects of Cinnamic Acid, Amygdalin, Glycyrrhizic Acid and Liquiritin on Ephedra Alkaloids in Rats.
PubMed:Antimutagenic components in Glycyrrhiza against N-methyl-N-nitrosourea in the Ames assay.
PubMed:Protective Effects of Liquiritin on the Brain of Rats with Alzheimer's Disease.
PubMed:Simultaneous Determination of 18 Chemical Constituents in Traditional Chinese Medicine of Antitussive by UPLC-MS-MS.
PubMed:Development and Validation of an UHPLC-QqQ-MS Technique for Simultaneous Determination of Ten Bioactive Components in Fangji Huangqi Tang.
PubMed:Ultra high performance liquid chromatography coupled with triple quadrupole mass spectrometry and chemometric analysis of licorice based on the simultaneous determination of saponins and flavonoids.
PubMed:[An exploration in the action targets for antidepressant bioactive components of Xiaoyaosan based on network pharmacology].
PubMed:[comparisons of pharmacokinetic profile of eleven bioactive components in Haizao Yuhu decoction modified with Haizao and Gancao anti-drug pair in normal rats].
PubMed:[Effect of exogenous sucrose on growth and active ingredient content of licorice seedlings under salt stress conditions].
PubMed:[Study on intestinal absorption of ingredients from different compatibilities of Shaoyao Gancao decoction].
PubMed:[In vitro microdialysis recoveries of nine active ingredients in Mahuang decoction].
PubMed:Rhein 8-O-β-D-Glucopyranoside Elicited the Purgative Action of Daiokanzoto (Da-Huang-Gan-Cao-Tang), Despite Dysbiosis by Ampicillin.
PubMed:Assessment of genetic fidelity and composition: Mixed elicitors enhance triterpenoid and flavonoid biosynthesis of Glycyrrhiza uralensis Fisch. tissue cultures.
PubMed:Hepatoprotective effect of licorice, the root of Glycyrrhiza uralensis Fischer, in alcohol-induced fatty liver disease.
PubMed:Analysis of bioactive components and pharmacokinetic study of herb-herb interactions in the traditional Chinese patent medicine Tongmai Yangxin Pill.
PubMed:Development of Double Eastern Blotting for Major Licorice Components, Glycyrrhizin and Liquiritin for Chemical Quality Control of Licorice Using anti-Glycyrrhizin and anti-Liquiritin Monoclonal Antibodies.
PubMed:[Effect of exogenous brassinolide on morphological characters and contents of seven chemical constituents of Glycyrrhiza uralensis].
PubMed:[Changes of specific chromatograms and contents of five components in Yinqiao powder decoctions during decocting process].
PubMed:Pharmacokinetics of Maxing Shigan decoction in normal rats and RSV pneumonia model rats by HPLC-MS/MS.
PubMed:The comparative pharmacokinetics of four bioactive ingredients after administration of Ramulus Cinnamomi-Radix Glycyrrhizae herb pair extract, Ramulus Cinnamomi extract and Radix Glycyrrhizae extract.
PubMed:Online near-infrared analysis coupled with MWPLS and SiPLS models for the multi-ingredient and multi-phase extraction of licorice (Gancao).
PubMed:[Feature Selection and Interpretation in Infrared Quantitative Models of Liquiritin and Glycyrrhizin in Radix Glycyrrhizae].
PubMed:Simultaneous quantification of catechin, epicatechin, liquiritin, isoliquiritin, liquiritigenin, isoliquiritigenin, piperine and glycyrrhetinic acid in rat plasma by HPLC-MS/MS: application to a pharmacokinetic study of Longhu Rendan pills.
PubMed:[Simultaneous Determination of Index Components in Wuwei Shaji Oral Liquid by HPLC].
PubMed:Aspergillus niger Enhance Bioactive Compounds Biosynthesis As Well As Expression of Functional Genes in Adventitious Roots of Glycyrrhiza uralensis Fisch.
PubMed:Combination of the advantages of chromatographic methods based on active components for the quality evaluation of licorice.
PubMed:[Relationship Between Seedling Grade of Glycyrrhiza uralensis and Plant Biomass Accumulation, Yield and Quality of Product].
PubMed:Two New Compounds from Hedyotis lindleyana.
PubMed:HPLC-PDA Method for Simultaneous Determination of Nine Marker Components in Banhasasim-Tang.
PubMed:[Effects of abscisic acid on chemical components content and color of Glycyrrhiza uralensis].
PubMed:Analysis of main constituents and mechanisms underlying antidepressant-like effects of Xiaochaihutang in mice.
PubMed:Simultaneous determination of nine marker compounds in the traditional Korean medicine, Dangguisu-san by high-performance liquid chromatography.
PubMed:Simultaneous determination of ten compounds in rat plasma by UPLC-MS/MS: Application in the pharmacokinetic study of Ma-Zi-Ren-Wan.
PubMed:Anti-Inflammatory activities of licorice extract and its active compounds, glycyrrhizic acid, liquiritin and liquiritigenin, in BV2 cells and mice liver.
PubMed:Antibacterial evaluation of flavonoid compounds against E. coli by microcalorimetry and chemometrics.
PubMed:An Ultra-Performance Liquid Chromatography Photodiode Array Detection Tandem Mass Spectrometric Method for Simultaneous Determination of Seven Major Bioactive Constituents in Xiaochaihutang and Its Application to Fourteen Compatibilities Study.
PubMed:Comparisons of the pharmacokinetic profile of four bioactive components after oral administration of gan-sui-ban-xia decoction plus-minus gansui and gancao drug combination in normal rats.
PubMed:[Changing rules study of effective components of Glycyrrhizae Radix et Rhizoma before and after compatibilities in Sini decoction].
PubMed:Blood-brain barrier permeability of Gualou Guizhi granules and neuroprotective effects in ischemia/reperfusion injury.
PubMed:Monitoring and evaluating the quality consistency of Compound Bismuth Aluminate tablets by a simple quantified ratio fingerprint method combined with simultaneous determination of five compounds and correlated with antioxidant activities.
PubMed:Comparative pharmacokinetics of puerarin, daidzin, baicalin, glycyrrhizic acid, liquiritin, berberine, palmatine and jateorhizine by liquid chromatography-mass spectrometry after oral administration of Gegenqinlian decoction and active components alignment (ACA) to rats.
PubMed:Effect of genotype and environment on five bioactive components of cultivated licorice (Glycyrrhiza uralensis) populations in northern China.
PubMed:Plant-derived natural medicines for the management of depression: an overview of mechanisms of action.
PubMed:Effects of herbal drugs in Mahuang decoction and their main components on intestinal transport characteristics of Ephedra alkaloids evaluated by a Caco-2 cell monolayer model.
PubMed:A protective mechanism of licorice (Glycyrrhiza uralensis): isoliquiritigenin stimulates detoxification system via Nrf2 activation.
PubMed:[Study on correlation between trace elements and active ingredient in glycyrrhizae radix et rhizome].
PubMed:Potential mechanisms of an antiadenomyosis chinese herbal formula shaoyao-gancao decoction in primary cell culture model.
PubMed:Simultaneous Determination of Nine Active Compounds of the Traditional Chinese Medicinal Prescription Shaoyao-Gancao-Tang and Analysis of the Relationship between Therapeutical Effect and Compatibility of Medicines.
PubMed:Simultaneous HPLC determination of four active compounds in fengshiding capsules, a chinese medicine.
PubMed:Preliminary identification of the absorbed bioactive components and metabolites in rat plasma after oral administration of Shaoyao-Gancao decoction by ultra-performance liquid chromatography with electrospray ionization tandem mass spectrometry.
PubMed:Effect of genotype and environment on five bioactive components of cultivated licorice (Glycyrrhiza uralensis FISCH.) populations in northern China.
PubMed:[Pharmacokinetic study on peoniflorin, astilbin, rosmarinic acid, isofraxidin and liquiritin in rat blood after oral administration of shaolin xiaoyin tablets].
PubMed:[Quantitative estimation of glycyrrhizic acid and liquiritin contents using in-situ canopy spectroscopy].
PubMed:A Chinese medicine formula Gegen Qinlian decoction suppresses expansion of human renal carcinoma with inhibition of matrix metalloproteinase-2.
PubMed:Production of rubusoside from stevioside by using a thermostable lactase from Thermus thermophilus and solubility enhancement of liquiritin and teniposide.
PubMed:LC-MS/MS analysis of Gegen Qinlian Decoction and its pharmacokinetics after oral administration to rats.
PubMed:Orthogonal Analysis Underscores the Relevance of Primary and Secondary Metabolites in Licorice.
PubMed:Enhanced skin delivery of liquiritigenin and liquiritin-loaded liposome-in-hydrogel complex system.
PubMed:Synergy of licorice extract and pea protein hydrolysate for oxidative stability of soybean oil-in-water emulsions.
PubMed:Chemical interaction between Paeonia lactiflora and Glycyrrhiza uralensis, the components of Jakyakgamcho-tang, using a validated high-performance liquid chromatography method: herbal combination and chemical interaction in a decoction.
PubMed:Simultaneous determination of liquiritin, nodakenin and glycyrrhizinin Guibi-tang, a traditional herbal prescription by HPLC-PDA.
PubMed:Bioactive profiles, antioxidant activities, nitrite scavenging capacities and protective effects on H2O2-injured PC12 cells of Glycyrrhiza glabra L. leaf and root extracts.
PubMed:Simultaneous Quantification of Ten Active Components in Traditional Chinese Formula Sijunzi Decoction Using a UPLC-PDA Method.
PubMed:Liquiritin modulates ERK‑ and AKT/GSK‑3β‑dependent pathways to protect against glutamate‑induced cell damage in differentiated PC12 cells.
PubMed:Distribution patterns of the contents of five active components in taproot and stolon of Glycyrrhiza uralensis.
PubMed:Preparative isolation and analysis of alcohol dehydrogenase inhibitors from Glycyrrhiza uralensis root using ultrafiltration combined with high-performance liquid chromatography and high-speed countercurrent chromatography.
PubMed:Simultaneous determination of 12 index components and compatibility changes in Longchai decoction by liquid chromatography-mass spectrometry.
PubMed:The effects of Glycyrrhizae uralenis and its major bioactive components on pharmacokinetics of daphnetin in Cortex daphnes in rats.
PubMed:Identification and pharmacokinetics of multiple constituents in rat plasma after oral administration of Yinchenzhufu decoction.
PubMed:A validated high performance liquid chromatograph-photodiode array method for simultaneous determination of 10 bioactive components in compound hongdoushan capsule.
PubMed:Simultaneous determination of 13 chemical marker compounds in Gwakhyangjeonggi-san, a herbal formula, with validated analytical methods.
PubMed:Intervention effects of QRZSLXF, a Chinese medicinal herb recipe, on the DOR-β-arrestin1-Bcl2 signal transduction pathway in a rat model of ulcerative colitis.
PubMed:Simultaneous determination of puerarin, daidzin, daidzein, paeoniflorin, albiflorin, liquiritin and liquiritigenin in rat plasma and its application to a pharmacokinetic study of Ge-Gen Decoction by a liquid chromatography-electrospray ionization-tandem mass spectrometry.
PubMed:Development of a monoclonal antibody-based immunochemical assay for liquiritin and its application to the quality control of licorice products.
PubMed:Effect of liquiritin on human intestinal bacteria growth: metabolism and modulation.
PubMed:Antidepressant-like effects of Xiaochaihutang in a rat model of chronic unpredictable mild stress.
PubMed:[Analysis and comparison of intestinal absorption of components of Gegenqinlian decoction in different combinations based on pharmacokinetic parameters].
PubMed:Simultaneous quantification and inhibitory effect on LDL oxidation of the traditional Korean medicine, Leejung-tang.
PubMed:Computer-guided approach to access the anti-influenza activity of licorice constituents.
PubMed:Combination of liquiritin, isoliquiritin and isoliquirigenin induce apoptotic cell death through upregulating p53 and p21 in the A549 non-small cell lung cancer cells.
PubMed:[Simultaneous determination of six ingredients in Huoxiang Zhengqi oral liquid by UPLC].
PubMed:[Development of a rapid screening method for discovering neuroprotective components from traditional Chinese medicine].
PubMed:[Genotype, environment and their interactions of major bioactive components in 2-year licorice (Glycyrrhiza uralensis) population].
PubMed:Evaluation of cytotoxiciy and tumor-specificity of licorice flavonoids based on chemical structure.
PubMed:A novel concept for detoxification: complexation between aconitine and liquiritin in a Chinese herbal formula ('Sini Tang').
PubMed:Simultaneous separation of triterpenoid saponins and flavonoid glycosides from the roots of Glycyrrhiza uralensis Fisch by pH-zone-refining counter-current chromatography.
PubMed:Employing bifunctional enzymes for enhanced extraction of bioactives from plants: flavonoids as an example.
PubMed:Pharmacokinetic comparisons of two different combinations of Shaoyao-Gancao Decoction in rats: competing mechanisms between paeoniflorin and glycyrrhetinic acid.
PubMed:Pharmacokinetic comparisons of different combinations of Shaoyao-Gancao-Decoction in rats: simultaneous determination of ten active constituents by HPLC-MS/MS.
PubMed:[Phenolic constituents from Lysimachia patungensis].
PubMed:Pharmacokinetic study of four flavones of Glycyrrhiza in rat plasma using HPLC-MS.
PubMed:[Study on in vitro anti-inflammatory activity of total flavonoids from Glycyrrhizae Radix et Rhizoma and its ingredients].
PubMed:Simultaneous quantification of paeoniflorin, nobiletin, tangeretin, liquiritigenin, isoliquiritigenin, liquiritin and formononetin from Si-Ni-San extract in rat plasma and tissues by liquid chromatography-tandem mass spectrometry.
PubMed:Isolation of liquiritigenin-4'-apiosyl-glucoside and liquiritin from the root of Glycyrrhiza uralensis by high-performance centrifugal partition chromatography.
PubMed:[Intestinal absorption of different combinations of active compounds from Gegenqinlian decoction by rat single pass intestinal perfusion in situ].
PubMed:[Cellular absorption of the active ingredients in different compatibilities of gegenqinlian decoction in human intestinal Caco-2 cells].
PubMed:Simultaneous determination of five bioactive components in radix glycyrrhizae by pressurised liquid extraction combined with UPLC-PDA and UPLC/ESI-QTOF-MS confirmation.
PubMed:Facile optimization for chromatographic separation of liquiritin and liquiritigenin.
PubMed:Research progress on flavonoids isolated from traditional Chinese medicine in treatment of Alzheimer's disease.
PubMed:Simultaneous quantitative determination of nine active chemical compositions in traditional Chinese medicine Glycyrrhiza by RP-HPLC with full-time five-wavelength fusion method.
PubMed:Subacute toxicity and stability of Soshiho-tang, a traditional herbal formula, in Sprague-Dawley rats.
PubMed:Development of sample preparation method for isoliquiritigenin, liquiritin, and glycyrrhizic acid analysis in licorice by ionic liquids-ultrasound based extraction and high-performance liquid chromatography detection.
PubMed:Liquiritin attenuates advanced glycation end products-induced endothelial dysfunction via RAGE/NF-κB pathway in human umbilical vein endothelial cells.
PubMed:Comparative study of bioactive constituents in crude and processed Glycyrrhizae radix and their respective metabolic profiles in gastrointestinal tract in vitro by HPLC-DAD and HPLC-ESI/MS analyses.
PubMed:Antispasmodic effect of shakuyakukanzoto extract on experimental muscle cramps in vivo: role of the active constituents of Glycyrrhizae radix.
PubMed:Comparative analysis of the main bioactive components of San-ao decoction and its series of formulations.
PubMed:Deglycosylation of liquiritin strongly enhances its inhibitory potential towards UDP-glucuronosyltransferase (UGT) isoforms.
PubMed:Effect of hypaconitine combined with liquiritin on the expression of calmodulin and connexin43 in rat cardiac muscle in vivo.
PubMed:An investigation of the antidepressant action of xiaoyaosan in rats using ultra performance liquid chromatography-mass spectrometry combined with metabonomics.
PubMed:Variations in the composition of Fructus Evodiae after processing with Radix Glycyrrhizae extract.
PubMed:Analytical strategy to reveal the in vivo process of multi-component herbal medicine: a pharmacokinetic study of licorice using liquid chromatography coupled with triple quadrupole mass spectrometry.
PubMed:[Multiple analysis of the difference in intestinal absorption between the main components and the extract of Glycyrrhiza uralensis].
PubMed:[Influence of combination on the specific chromatogram of Glycyrrhiza in sini decoctions by HPLC].
PubMed:[Simultaneous determination of four components in sini tang by HPLC].
PubMed:[Absorption of flavones in Gegenqinlian decoction and different compatibilities in rat everted gut scas].
PubMed:Determination of 5-hydroxymethyl-2-furfural, albiflorin, paeoniflorin, liquiritin, ferulic acid, nodakenin, and glycyrrhizin by HPLC-PDA, and evaluation of the cytotoxicity of Palmul-tang, a traditional Korean herbal medicine.
PubMed:Characterization and quantification of major constituents of Xue Fu Zhu Yu by UPLC-DAD-MS/MS.
PubMed:[Identification of the metabolites of Sinisan extract in rat plasma, urine, feces and bile after intragastric administration].
PubMed:Simultaneous determination of seven constituents in herbal prescription jaeumganghwa-tang using HPLC-PDA.
PubMed:Influence of honey-roasting on the main pharmacological activities and the water-soluble active glycosides of licorice.
PubMed:Absorption and interaction of the main constituents from the traditional Chinese drug pair Shaoyao-Gancao via a Caco-2 cell monolayer model.
PubMed:[Effect of Tongfeng trace elements nutrient balance agent on growth, physiological characteristics and content of active constituents of Glycyrrhiza uralensis].
PubMed:Simultaneous determination of naringin, hesperidin, neohesperidin, naringenin and hesperetin of Fractus aurantii extract in rat plasma by liquid chromatography tandem mass spectrometry.
PubMed:High-performance liquid chromatographic determination and metabolic study of sennoside a in daiokanzoto by mouse intestinal bacteria.
PubMed:The influence of glycyrrhiza and antibiotics on the purgative action of sennoside a from Daiokanzoto in mice.
PubMed:Variation of glycyrrhizin and liquiritin contents within a population of 5-year-old licorice (Glycyrrhiza uralensis) plants cultivated under the same conditions.
PubMed:Effects of brucine combined with glycyrrhetinic acid or liquiritin on rat hepatic cytochrome P450 activities in vivo.
PubMed:Isoliquiritigenin is a novel NMDA receptor antagonist in kampo medicine yokukansan.
PubMed:Protective effects of liquiritin apioside on cigarette smoke-induced lung epithelial cell injury.
PubMed:[Determination of liquiritin, naringin, hesperidin and glycyrrhizic acid in extractive of Wendan formula by RP-HPLC].
PubMed:Simultaneous determination of liquiritin, hesperidin, and glycyrrhizin by HPLC-photodiode array detection and the anti-inflammatory effect of Pyungwi-san.
PubMed:Optimization of micellar electrokinetic capillary chromatography method using central composite design for the analysis of components in Yangwei granule.
PubMed:[In vitro absorption mechanism of strychnine and the transport interaction with liquiritin in Caco-2 cell monolayer model].
PubMed:Identification and determination of the major constituents in traditional Chinese medicine Longdan Xiegan Pill by HPLC-DAD-ESI-MS.
PubMed:[On-line sample stacking for the analysis of glycyrrhiza flavonoids by anion selective exhaustive injection-sweeping micellar electrokinetic chromatography].
PubMed:Neuroprotective effect of liquiritin against focal cerebral ischemia/reperfusion in mice via its antioxidant and antiapoptosis properties.
PubMed:Genotoxicity assessment of Pyungwi-san (PWS), a traditional herbal prescription.
PubMed:[Studies on changes of in vitro and in vivo material base of Shaoyao Gancao decoction based on HPLC-DAD-ESI-MS].
PubMed:Solid-phase extraction of liquiritin and glycyrrhizin from licorice using porous alkyl-pyridinium polymer sorbent.
PubMed:[Application of FTIR spectroscopy to the identification of Glycyrrhiza uralensis Fisch].
PubMed:[Investigation on medicinal plant resources of Glycyrrhiza uralensis in China and chemical assessment of its underground part].
PubMed:Licorice infusion: Chemical profile and effects on the activation and the cell cycle progression of human lymphocytes.
PubMed:Rapid profiling and target analysis of principal components in Fuling Decoctions by UFLC-DAD-ESI-MS.
PubMed:Separation, characterization and dose-effect relationship of the PPARgamma-activating bio-active constituents in the Chinese herb formulation 'San-Ao decoction'.
PubMed:Effects of space flight on DNA mutation and secondary metabolites of licorice (Glycyrrhiza uralensis Fisch.).
PubMed:Solid-phase extraction of liquiritin and glycyrrhizic acid from licorice using ionic liquid-based silica sorbent.
PubMed:Liquiritin potentiate neurite outgrowth induced by nerve growth factor in PC12 cells.
PubMed:Qualitative and quantitative analysis of traditional Chinese medicine Niu Huang Jie Du Pill using ultra performance liquid chromatography coupled with tunable UV detector and rapid resolution liquid chromatography coupled with time-of-flight tandem mass spectrometry.
PubMed:Simultaneous determination of five flavonoids in licorice using pressurized liquid extraction and capillary electrochromatography coupled with peak suppression diode array detection.
PubMed:Simultaneous determination of puerarin, daidzein, baicalin, wogonoside and liquiritin of GegenQinlian decoction in rat plasma by ultra-performance liquid chromatography-mass spectrometry.
PubMed:Liquiritigenin, a licorice flavonoid, helps mice resist disseminated candidiasis due to Candida albicans by Th1 immune response, whereas liquiritin, its glycoside form, does not.
PubMed:[Fingerprint analysis of Radix Glycyrrhizae by fast HPLC].
PubMed:Licorice flavonoids inhibit eotaxin-1 secretion by human fetal lung fibroblasts in vitro.
PubMed:Survey of Glycyrrhizae Radix resources in Mongolia: chemical assessment of the underground part of Glycyrrhiza uralensis and comparison with Chinese Glycyrrhizea Radix.
PubMed:Simultaneous determination of 12 chemical constituents in the traditional Chinese Medicinal Prescription Xiao-Yao-San-Jia-Wei by HPLC coupled with photodiode array detection.
PubMed:Transport and metabolism of flavonoids from Chinese herbal remedy Xiaochaihu- tang across human intestinal Caco-2 cell monolayers.
PubMed:Antidepressant-like effect of liquiritin from Glycyrrhiza uralensis in chronic variable stress induced depression model rats.
PubMed:[Neuroprotection and neurotrophism effects of liquiritin on primary cultured hippocampal cells].
PubMed:Isoliquiritigenin suppresses cocaine-induced extracellular dopamine release in rat brain through GABA(B) receptor.
PubMed:[Selective adsorption of multi-walled carbon nanotubes with liquiritin and isoliquiritin].
PubMed:Antidepressant-like effects of liquiritin and isoliquiritin from Glycyrrhiza uralensis in the forced swimming test and tail suspension test in mice.
PubMed:Analysis of glycyrrhizic acid and liquiritin in liquorice root with microwave-assisted micellar extraction and pre-concentration.
PubMed:Simultaneous analysis of glycyrrhizin, paeoniflorin, quercetin, ferulic acid, liquiritin, formononetin, benzoic acid and isoliquiritigenin in the Chinese proprietary medicine Xiao Yao Wan by HPLC.
PubMed:Constituent properties of licorices derived from Glycyrrhiza uralensis, G. glabra, or G. inflata identified by genetic information.
PubMed:[Relative adscriptions of components in the effective fractions of Yinqiao decoction and its composing individual herbs].
PubMed:Simultaneous quantification of multiple licorice flavonoids in rat plasma.
PubMed:Separation of Liquiritin by simulated moving bed chromatography.
PubMed:Simultaneous quantification of flavonoids and triterpenoids in licorice using HPLC.
PubMed:Determination of liquiritin, naringin, hesperidin, thymol, imperatorin, honokiol, isoimperatorin, and magnolol in the traditional Chinese medicinal preparation Huoxiang-zhengqi liquid using high-performance liquid chromatography.
PubMed:Liquiritigenin, an aglycone of liquiritin in Glycyrrhizae radix, prevents acute liver injuries in rats induced by acetaminophen with or without buthionine sulfoximine.
PubMed:Application of LC/MS and ICP/MS for establishing the fingerprint spectrum of the traditional Chinese medicinal preparation Gan-Lu-Yin.
PubMed:Norditerpenoid alkaloids and other components from the processed tubers of Aconitum carmichaeli.
PubMed:CYP3A4 inhibitors isolated from Licorice.
PubMed:Isolation and identification of flavonoids in licorice and a study of their inhibitory effects on tyrosinase.
PubMed:Analysis and comparison of Radix Glycyrrhizae (licorice) from Europe and China by capillary-zone electrophoresis (CZE).
PubMed:[Effects of Chinese herbal medicines on intestinal drug absorption].
PubMed:Pharmacokinetic and pharmacodynamic profiles of the antitussive principles of Glycyrrhizae radix (licorice), a main component of the Kampo preparation Bakumondo-to (Mai-men-dong-tang).
PubMed:Separation and isolation methods for analysis of the active principles of Sho-saiko-to (SST) oriental medicine.
PubMed:Cytoprotective effects of Glycyrrhizae radix extract and its active component liquiritigenin against cadmium-induced toxicity (effects on bad translocation and cytochrome c-mediated PARP cleavage).
PubMed:[Isolation and elucidation of chemical constituents with antiviral action from yinqiaosan on influenza virus].
PubMed:Permeability of the flavonoids liquiritigenin and its glycosides in licorice roots and davidigenin, a hydrogenated metabolite of liquiritigenin, using human intestinal cell line Caco-2.
PubMed:Pharmacokinetic study on the multi-constituents of Huangqin-Tang decoction in rats.
PubMed:Antitussive principles of Glycyrrhizae radix, a main component of the Kampo preparations Bakumondo-to (Mai-men-dong-tang).
PubMed:[Study on the chemical components of Rabdosia excisa].
PubMed:Metabolism of constituents in Huangqin-Tang, a prescription in traditional Chinese medicine, by human intestinal flora.
PubMed:Determination of 14 chemical constituents in the traditional Chinese medicinal preparation Huangqin-Tang by high performance liquid chromatography.
PubMed:Dissolution profiles of principal ingredients in Kampo medicinal powders by high-performance liquid chromatography.
PubMed:Topical liquiritin improves melasma.
PubMed:Modulation of lung local immune responses by oral administration of a herbal medicine Sho-saiko-to.
PubMed:Simultaneous high-performance liquid chromatographic determination of puerarin, daidzin, paeoniflorin, liquiritin, cinnamic acid, cinnamaldehyde and glycyrrhizin in Kampo medicines.
PubMed:[Quantitative determination of constituents in various licorice roots by means of high performance liquid chromatography].
PubMed:Relationship between hydrophobicity and structure of hydrolyzable tannins, and association of tannins with crude drug constituents in aqueous solution.
PubMed:[Chemical components of decoction of radix Paeoniae and radix Glycyrrhizae].
PubMed:Modifying effects of naturally occurring products on the development of colonic aberrant crypt foci induced by azoxymethane in F344 rats.
PubMed:Inhibitory effects of flavonoids on xanthine oxidase.
PubMed:High-performance liquid chromatographic method for the determination of mangiferin, likviritin and dihydroquercetin in rat plasma and urine.
PubMed:[Chemical studies of coumarins from Glycyrrhiza uralensis Fisch].
PubMed:[Quality evaluation of Chinese licorice].
PubMed:[HPLC analysis of flavonoids in the root of six Glycyrrhiza species].
PubMed:[Studies on chemical constituents of Glycyrrhiza eurycarpa P. C. Li].
PubMed:[STUDY OF THE ENZYME HYDROLYSIS LIQUIRITIN].
PubMed:[On the isolation and a new decomposition of liquiritin from licorice root].
PubMed:[Liquiritoside, flavonoside from root of licorice, Glycyrrhiza glabra L].
 
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