visnadine, 477-32-7

Supplier Sponsors

CAS Number:	477-32-7	3D/inchi
ECHA EINECS - REACH Pre-Reg:	207-515-1
FDA UNII:	0RL4V0K263
Nikkaji Web:	J67.394C
XlogP3-AA:	3.40 (est)
Molecular Weight:	388.41668000
Formula:	C21 H24 O7
NMR Predictor:	Predict (works with chrome, Edge or firefox)

Category:cosmetic ingredient for skin conditioning

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
Google Books:	Search
Google Scholar: with word "volatile"	Search
Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search

Physical Properties:

Assay:	95.00 to 100.00
Food Chemicals Codex Listed:	No
Soluble in:
	water, 2.38 mg/L @ 25 °C (est)

Organoleptic Properties:

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

CosIng:	cosmetic data
Cosmetic Uses:	skin conditioning

Suppliers:

None found

Safety Information:


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-dog LDLo 20 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 283, 1967. oral-dog LDLo 200 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 283, 1967. intramuscular-mouse LD50 832 mg/kg Journal of Drug Research. Vol. 7(2), Pg. 1, 1975. oral-mouse LD50 2240 mg/kg LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 283, 1967. intravenous-rabbit LDLo 50 mg/kg LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 283, 1967. oral-rabbit LDLo > 600 mg/kg LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 283, 1967. oral-rat LD50 1213 mg/kg Journal of Drug Research. Vol. 7(2), Pg. 1, 1975.
Dermal Toxicity:
subcutaneous-mouse LD50 > 370 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA Arzneimittel-Forschung. Drug Research. Vol. 17, Pg. 283, 1967.
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
cosmetic ingredient for skin conditioning
Recommendation for visnadine usage levels up to:
	not for fragrance use.

Recommendation for visnadine flavor usage levels up to:
	not for flavor use.

Safety References:

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :442151

National Institute of Allergy and Infectious Diseases:Data

WGK Germany:3

acetyloxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-f]chromen-9-yl] (2R)-2-methylbutanoate

Chemidplus:0000477327

References:

	acetyloxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-f]chromen-9-yl] (2R)-2-methylbutanoate
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	442151
Pubchem (sid):	134973667

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
CHEBI:	View
KEGG (GenomeNet):	C09316
HMDB (The Human Metabolome Database):	Search
ChemSpider:	View
Wikipedia:	View

Potential Blenders and core components note

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):note

not found in nature

Synonyms:

[(9R,10R)-10-	acetyloxy-8,8-dimethyl-2-oxo-9,10-dihydropyrano[2,3-f]chromen-9-yl] (2R)-2-methylbutanoate
	butanoic acid, 2-methyl-, (9R,10R)-10-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-9-yl ester, (2R)-

Articles:

PubMed:Randomized crossover study investigating daily versus on-demand vulvar Visnadine spray in women affected by female sexual arousal disorder.

PubMed:Effects of visnadine on rat isolated vascular smooth muscles.

PubMed:Study of the action of visnadine on general and cardiac hemodynamics.

PubMed:[Coronary treatment with visnadine].

PubMed:[Studies on the effect of the coronary active substance (Visnadine) on fat and carbohydrate metabolism].

PubMed:[Clinical observations on the effect of Visnadine in acute myocardial lesions].

PubMed:[The effect of Visnadine in chronic degenerative myocardial lesions].

PubMed:[On the chemistry, pharmacology and toxicology of Visnadine].

PubMed:[A further contribution to the study of biological effects of visnadine].

PubMed:[VISNADINE IN THE TREATMENT OF MYOCARDIAL INFARCT AND CORONARY DISEASE].

Notes:

None found

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visnadine butanoic acid, 2-methyl-, (9R,10R)-10-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-9-yl ester, (2R)-

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Articles:

visnadine
butanoic acid, 2-methyl-, (9R,10R)-10-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-9-yl ester, (2R)-