telmesteine
3,4-thiazolidinedicarboxylic acid, 3-ethyl ester, (R)-
 
Notes:
None found
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(4R)-3-ethoxycarbonyl-1,3-thiazolidine-4-carboxylic acid (Click)
CAS Number: 122946-43-4Picture of molecule
FDA UNII: 124I3FE35T
Nikkaji Web: J561.874F
MDL: MFCD00867667
XlogP3: 0.60 (est)
Molecular Weight: 205.23347000
Formula: C7 H11 N O4 S
NMR Predictor: Predict (works with chrome or firefox)
Category: antioxidants
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
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Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
IBM Patents: Obtain
Pubchem Patents: Search
PubMed: Search
NCBI: Search
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Soluble in:
 water, 9.987e+004 mg/L @ 25 °C (est)
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Organoleptic Properties:
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: antioxidants
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: antioxidants
Recommendation for telmesteine usage levels up to:
 not for fragrance use.
 
Recommendation for telmesteine flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 65946
National Institute of Allergy and Infectious Diseases: Data
 (4R)-3-ethoxycarbonyl-1,3-thiazolidine-4-carboxylic acid
Chemidplus: 0122946434
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References:
 (4R)-3-ethoxycarbonyl-1,3-thiazolidine-4-carboxylic acid
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 65946
Pubchem (sid): 135025373
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEMBL: View
KEGG (GenomeNet): D08565
HMDB (The Human Metabolome Database): Search
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
(4R)-3-ethoxycarbonyl-1,3-thiazolidine-4-carboxylic acid
3,4-thiazolidinedicarboxylic acid, 3-ethyl ester, (R)-
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Articles:
PubMed: Treatment of pruritus in mild-to-moderate atopic dermatitis with a topical non-steroidal agent.
PubMed: A double-blind, randomised, vehicle-controlled clinical study to evaluate the efficacy of MAS065D in limiting the effects of radiation on the skin: interim analysis.
PubMed: Treatment of mild to moderate seborrhoeic dermatitis with MAS064D (Sebclair), a novel topical medical device: results of a pilot, randomized, double-blind, controlled trial.
PubMed: Suppression of diabetes-induced retinal inflammation by blocking the angiotensin II type 1 receptor or its downstream nuclear factor-kappaB pathway.
PubMed: A double-blind, vehicle-controlled clinical study to evaluate the efficacy of MAS065D (XClair), a hyaluronic acid-based formulation, in the management of radiation-induced dermatitis.
PubMed: Steroids versus other immune modulators in the management of allergic dermatoses.
PubMed: A multicenter, randomized, vehicle-controlled clinical study to examine the efficacy and safety of MAS063DP (Atopiclair) in the management of mild to moderate atopic dermatitis in adults.
PubMed: A randomised, double-blind, vehicle-controlled study to evaluate the efficacy and safety of MAS063D (Atopiclair) in the treatment of mild to moderate atopic dermatitis.
PubMed: Absorption, distribution, metabolism and excretion of telmesteine, a mucolitic agent, in rat.
PubMed: [Telemestein and variations in blood concentrations of lipoprotein A].
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