sodium polyphosphate
polyphosphoric acids, sodium salts
None found
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disodium;[hydroxy(oxido)phosphoryl] hydrogen phosphate (Click)
CAS Number: 68915-31-1Picture of molecule
Other: 197527-53-0
ECHA EINECS - REACH Pre-Reg: 272-808-3
Molecular Weight: 221.93740256
Formula: H2 Na2 O7 P2
NMR Predictor: Predict (works with chrome or firefox)
Category: chelating agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
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Organoleptic Properties:
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: chelating agents
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 None found
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Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: chelating agents
Recommendation for sodium polyphosphate usage levels up to:
 not for fragrance use.
Recommendation for sodium polyphosphate flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
EPA Substance Registry Services (TSCA): 68915-31-1
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 24451
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 1
 disodium;[hydroxy(oxido)phosphoryl] hydrogen phosphate
Chemidplus: 0068915311
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 disodium;[hydroxy(oxido)phosphoryl] hydrogen phosphate
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 68915-31-1
Pubchem (cid): 24451
Pubchem (sid): 135316753
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
ChemSpider: View
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Potential Blenders and core components note
None Found
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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 disodium;[hydroxy(oxido)phosphoryl] hydrogen phosphate
 polyphosphoric acids, sodium salts
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PubMed: pH influences hydrolysis of sodium polyphosphate in dairy matrices and the structure of processed cheese.
PubMed: Preparation and performance of biofouling resistant PAN/chitosan hollow fiber membranes.
PubMed: In situ evaluation of fluoride-, stannous- and polyphosphate-containing solutions against enamel erosion.
PubMed: Factors influencing gelation properties of corn germ proteins.
PubMed: Synthetic polyphosphate inhibits endogenous coagulation and platelet aggregation in vitro.
PubMed: Synthesis and factorial design applied to a novel chitosan/sodium polyphosphate nanoparticles via ionotropic gelation as an RGD delivery system.
PubMed: Platelet-Derived Short-Chain Polyphosphates Enhance the Inactivation of Tissue Factor Pathway Inhibitor by Activated Coagulation Factor XI.
PubMed: Effect of the cross-linking agent on performances of NaCS-CS/WSC microcapsules.
PubMed: Elution Is a Critical Step for Recovering Human Adenovirus 40 from Tap Water and Surface Water by Cross-Flow Ultrafiltration.
PubMed: Degradation and hemostatic properties of polyphosphate coacervates.
PubMed: Physicochemical properties of skim milk powders prepared with the addition of mineral chelators.
PubMed: A small volume procedure for viral concentration from water.
PubMed: Anti-erosive properties of solutions containing fluoride and different film-forming agents.
PubMed: Microarray analysis of the transcriptional responses of Porphyromonas gingivalis to polyphosphate.
PubMed: The importance of chain length for the polyphosphate enhancement of acidic potassium permanganate chemiluminescence.
PubMed: Comprehensive study of the chelation and coacervation of alkaline earth metals in the presence of sodium polyphosphate solution.
PubMed: Characterization of novel lactoferrin loaded capsules prepared with polyelectrolyte complexes.
PubMed: Optimization of adenovirus 40 and 41 recovery from tap water using small disk filters.
PubMed: Novel NaCS-CS-PPS microcapsules as a potential enzyme-triggered release carrier for highly-loading 5-ASA.
PubMed: Chitosan coated alginate/poly(N-isopropylacrylamide) beads for dual responsive drug delivery.
PubMed: Effectiveness of poliovirus concentration and recovery from treated wastewater by two electropositive filter methods.
PubMed: [Application of membrane separation technology in extraction process of Chuanxiong Chatiao granules].
PubMed: In situ evaluation of the erosive potential of orange juice modified by food additives.
PubMed: Slow complexation dynamics between linear short polyphosphates and polyallylamines: analogies with "layer-by-layer" deposits.
PubMed: Influence of the nature of the polycation on the adsorption kinetics and on exchange processes in polyelectrolyte multilayer films.
PubMed: Effects of polyphosphate additives on the pH of processed chicken exudates and the survival of Campylobacter.
PubMed: New method using a positively charged microporous filter and ultrafiltration for concentration of viruses from tap water.
PubMed: Antimicrobial effect of ammonium hydroxide when used as an alkaline agent in the formulation of injection brine solutions.
PubMed: Autocatalytic nature of permanganate oxidations exploited for highly sensitive chemiluminescence detection.
PubMed: Polyphosphate-doped polypyrrole coated on steel fiber for the solid-phase microextraction of organochlorine pesticides in water.
PubMed: Design of LabVIEW-based software for the control of sequential injection analysis instrumentation for the determination of morphine.
PubMed: Effects of salinity on physicochemical properties of Alaska pollock surimi after repeated freeze-thaw cycles.
PubMed: Ultrafiltration-based techniques for rapid and simultaneous concentration of multiple microbe classes from 100-L tap water samples.
PubMed: Fluorescent II-VI semiconductor quantum dots in living cells: nonlinear microspectroscopy in an optical tweezers system.
PubMed: Evaluation of 1MDS electropositive microfilters for simultaneous recovery of multiple microbe classes from tap water.
PubMed: Preparation of colloidal CdSe and CdS/CdSe nanoparticles from sodium selenosulfate in aqueous polymers solutions.
PubMed: Coexistence of liquid phases in the sodium polyphosphate-chromium nitrate-water system.
PubMed: Jamming and gelation of dense beta-casein micelle suspensions.
PubMed: Development of a rapid method for simultaneous recovery of diverse microbes in drinking water by ultrafiltration with sodium polyphosphate and surfactants.
PubMed: Dynamic mechanical properties of suspensions of micellar casein particles.
PubMed: Multinuclear NMR studies on the sol-gel preparation of sodium aluminophosphate glasses.
PubMed: Production of a high gel strength whey protein concentrate from cheese whey.
PubMed: Determination of salbutamol using on-line solid-phase extraction and sequential injection analysis. Comparison of chemiluminescence and fluorescence detection.
PubMed: Effects of permeabilizers on antimicrobial susceptibility of Stenotrophomonas maltophilia and Acinetobacter spp.
PubMed: Maximization of recombinant Helicobacter pylori neutrophil activating protein production in Escherichia coli: improvement of a chemically defined medium using response surface methodology.
PubMed: Methods for determination of milt protein and epsilon-polylysine in food additive preparations and processed foods by capillary zone electrophoresis.
PubMed: Determination of morphine, oripavine and pseudomorphine using capillary electrophoresis with acidic potassium permanganate chemiluminescence detection.
PubMed: Aluminum Polyphosphate Nanoparticles: Preparation, Particle Size Determination, and Microchemistry.
PubMed: Effect of permeabilizers on antibiotic sensitivity of Pseudomonas aeruginosa.
PubMed: Effect of divalent cations on permeabilizer-induced lysozyme lysis of Pseudomonas aeruginosa.
PubMed: Use of the Malthus-AT system to assess the efficacy of permeabilizing agents on the activity of antibacterial agents against Pseudomonas aeruginosa.
PubMed: Phosphate glass as a phosphate source in high cell density Escherichia coli fermentations.
PubMed: Emulsification preparation of calcium alginate beads in the presence of sequesterant.
PubMed: X-ray-absorption spectroscopic studies of sodium polyphosphate glasses.
PubMed: [Clinical study of the anti-calculus effect of a dentifrice containing sodium polyphosphate].
PubMed: [Effects of sodium polyphosphate on the inhibition of calculus formation in vitro and animal test].
PubMed: Maturation of vacuolar (lysosomal) enzymes in yeast: proteinase yscA and proteinase yscB are catalysts of the processing and activation event of carboxypeptidase yscY.
PubMed: Novel method for the preparation of controlled-release theophylline granules coated with a polyelectrolyte complex of sodium polyphosphate-chitosan.
PubMed: Radiochemical purity of various 99mTc-labelled bone-scanning agents.
PubMed: [Evaluation of 99mTc sodium polyphosphate complex as a bone seeking agent].
PubMed: [Determination of reaction in the reticuloendothelial system after injection with omnadin and pyrifer by continuous measurement of polyphosphate clearance; study with P32 labeled calcium and sodium polyphosphate].
PubMed: [Further studies on the determination of reticuloendothelial clearance of macromolecules using P32-tagged potassium sodium polyphosphate. II].
PubMed: [Circulation studies in the dog with the aid of radiophosphorus-labelled calcium and sodium polyphosphate].
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