EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

fulvic acid
1H,3H-pyrano[4,3-b][1]benzopyran-9-carboxylic acid, 4,10-dihydro-3,7,8-trihydroxy-3-methyl-10-oxo

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Name:3,7,8-trihydroxy-3-methyl-10-oxo-1,4-dihydropyrano[4,3-b]chromene-9-carboxylic acid
CAS Number: 479-66-3Picture of molecule3D/inchi
Nikkaji Web:J127.110E
XlogP3-AA:0.30 (est)
Molecular Weight:308.24324000
Formula:C14 H12 O8
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:cosmetic ingredient for skin conditioning
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 1.393e+005 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: skin conditioning
BOC Sciences
For experimental / research use only.
Fulvic acid >95%
Glentham Life Sciences
Fulvic acid
Santa Cruz Biotechnology
For experimental / research use only.
Fulvic Acid ≥95%
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
cosmetic ingredient for skin conditioning
Recommendation for fulvic acid usage levels up to:
 not for fragrance use.
Recommendation for fulvic acid flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :5359407
National Institute of Allergy and Infectious Diseases:Data
3,7,8-trihydroxy-3-methyl-10-oxo-1,4-dihydropyrano[4,3-b]chromene-9-carboxylic acid
 3,7,8-trihydroxy-3-methyl-10-oxo-1,4-dihydropyrano[4,3-b]chromene-9-carboxylic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):5359407
Pubchem (sid):134974174
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 not found in nature
3,4-dihydro-3,7,8-trihydroxy-3-methyl-10-oxo-1H,10H-pyrano(4,3-b)(1)benzopyran-9-carboxylic acid
1H,3H-pyrano[4,3-b][1]benzopyran-9-carboxylic acid, 4,10-dihydro-3,7,8-trihydroxy-3-methyl-10-oxo
3,7,8-trihydroxy-3-methyl-10-oxo-1,4-dihydropyrano[4,3-b]chromene-9-carboxylic acid


PubMed:Distribution and translocation of selenium from soil to highland barley in the Tibetan Plateau Kashin-Beck disease area.
PubMed:[Vermicomposting of different organic materials and three-dimensional excitation emission matrix fluorescence spectroscopic characterization of their dissolved organic matter].
PubMed:Characterizing the interaction between uranyl ion and fulvic acid using regional integration analysis (RIA) and fluorescence quenching.
PubMed:[Spectrum characteristics of leaching components from co-contaminated loess in ex-situ column washing reaction].
PubMed:Fulvic acid mediates chromium (Cr) tolerance in wheat (Triticum aestivum L.) through lowering of Cr uptake and improved antioxidant defense system.
PubMed:Isolation and characterization of Chinese standard fulvic acid sub-fractions separated from forest soil by stepwise elution with pyrophosphate buffer.
PubMed:The use of solid-phase fluorescence spectroscopy in the characterisation of organic matter transformations.
PubMed:Evaluation of monitoring indicators for the post-closure care of a landfill for MSW characterized with low lignin content.
PubMed:Evaluation of humic substances during co-composting of food waste, sawdust and Chinese medicinal herbal residues.
PubMed:Relationship between anaerobic digestion of biodegradable solid waste and spectral characteristics of the derived liquid digestate.
PubMed:Effect of presence of cellulose in the freshwater sediment on the performance of sediment microbial fuel cell.
PubMed:Soil metabolism of [14C]methiozolin under aerobic and anaerobic flooded conditions.
PubMed:Characterization of the atrazine sorption process on Andisol and Ultisol volcanic ash-derived soils: kinetic parameters and the contribution of humic fractions.
PubMed:Can nutraceuticals prevent Alzheimer's disease? Potential therapeutic role of a formulation containing shilajit and complex B vitamins.
PubMed:Photodegradation of ormetoprim in aquaculture and stream-derived dissolved organic matter.
PubMed:Effects of soil properties on the transfer of cadmium from soil to wheat in the Yangtze River delta region, China--a typical industry-agriculture transition area.
PubMed:Investigation into organic phosphorus species in sediments of Baiyangdian Lake in China measured by fractionation and ³¹P NMR.
PubMed:Abiotic reduction of pendimethalin and trifluralin in controlled and natural systems containing Fe(II) and dissolved organic matter.
PubMed:Novel software for data analysis of Fourier transform ion cyclotron resonance mass spectra applied to natural organic matter.
PubMed:Complementary multianalytical approach to study the distinctive structural features of the main humic fractions in solution: gray humic acid, brown humic acid, and fulvic acid.
PubMed:Influence of fulvic acids and copper ions on thiram determination in water.
PubMed:Characterization of brewery wastewater with spectrofluorometry analysis.
PubMed:Multivariate statistical analysis of mass spectra as a tool for the classification of the main humic substances according to their structural and conformational features.
PubMed:Maturity assessment of composted olive mill wastes using UV spectra and humification parameters.
PubMed:Bioconversion of wastes from the olive oil and confectionary industries: spectroscopic study of humic acids.
PubMed:Environmental photochemistry of tylosin: efficient, reversible photoisomerization to a less-active isomer, followed by photolysis.
PubMed:Characterization of humic substances derived from swine manure-based compost and correlation of their characteristics with reactivities with heavy metals.
PubMed:Changes in organic matter and residual effect of amendment with two-phase olive-mill waste on degraded agricultural soils.
PubMed:Evolution of the fulvic acid fractions during co-composting of olive oil mill wastewater sludge and tree cuttings.
PubMed:Water remediation by micelle-clay system: case study for tetracycline and sulfonamide antibiotics.
PubMed:Modification of soil humic matter after 4 years of compost application.
PubMed:Compost effect on soil humic acid: A NMR study.
PubMed:Humic substances can modulate the allelopathic potential of caffeic, ferulic, and salicylic acids for seedlings of lettuce (Lactuca sativa L.) and tomato (Lycopersicon esculentum Mill.).
PubMed:Influence of water chemistry on the acute toxicity of copper and zinc to the cladoceran Ceriodaphnia cf dubia.
PubMed:Long-time fulvic acid supplementation modulates hydroxylysyl glycosylation of collagen in mice.
PubMed:Towards sustainable use of potassium in pineapple waste.
PubMed:Analysis of carbon and nitrogen forms in soil fractions after the addition of 15N-compost by 13C and 15N nuclear magnetic resonance.
PubMed:Influence of organic matter on the uptake of cadmium, zinc, copper and iron by sorghum plants.
PubMed:Characterization and biological activities of humic substances from mumie.
PubMed:Aerobic soil metabolism of a new herbicide, LGC-42153.
PubMed:Retention and extractability of phenol, cresol, and dichlorophenol exposed to two surface soils in the presence of horseradish peroxidase enzyme.
PubMed:Studies on bound (14)C-chlorsulfuron residues in soil.
PubMed:Aquatic humic substances inhibit clastogenic events in germinating seeds of herbaceous plants.
PubMed:Microbial release and degradation of nonextractable anilazine residues.
PubMed:Intestinal absorption of copper from drinking water containing fulvic acids and an infant formula mixture studied in a suckling rat model.
PubMed:Fulvic and humic acids decrease the absorption of cadmium in the rat intestine.
PubMed:Study on the pathogenic factors of Kashin-Beck disease.
None found
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