perfluoro t-butylcyclohexane
oxycyte
 
Notes:
None found
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1,1,2,2,3,3,4,4,5,5,6-undecafluoro-6-[1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)propan-2-yl]cyclohexane (Click)
CAS Number: 84808-64-0Picture of molecule
FDA UNII: 3ZX1Z33VUU
Nikkaji Web: J3.466.554K
XlogP3-AA: 7.00 (est)
Molecular Weight: 500.07806400
Formula: C10 F20
NMR Predictor: Predict (works with chrome or firefox)
Category: antistatic, hair conditioning
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Soluble in:
 water, 0.0001703 mg/L @ 25 °C (est)
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Organoleptic Properties:
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: antistatic agents
hair conditioning
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: antistatic, hair conditioning
Recommendation for perfluoro t-butylcyclohexane usage levels up to:
 not for fragrance use.
 
Recommendation for perfluoro t-butylcyclohexane flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
ClinicalTrials.gov: search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 15710945
National Institute of Allergy and Infectious Diseases: Data
 1,1,2,2,3,3,4,4,5,5,6-undecafluoro-6-[1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)propan-2-yl]cyclohexane
Chemidplus: 0084808640
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References:
 1,1,2,2,3,3,4,4,5,5,6-undecafluoro-6-[1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)propan-2-yl]cyclohexane
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 15710945
Pubchem (sid): 163640936
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
Wikipedia: View
RSC Learn Chemistry: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 cyclohexane, 1,1,2,2,3,3,4,4,5,5,6-undecafluoro-6-[2,2,2-trifluoro-1,1-bis(trifluoromethyl)ethyl]-
 oxycyte
1,1,2,2,3,3,4,4,5,5,6-undecafluoro-6-[1,1,1,3,3,3-hexafluoro-2-(trifluoromethyl)propan-2-yl]cyclohexane
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Articles:
PubMed: In vitro alteration of hematological parameters and blood viscosity by the perfluorocarbon: Oxycyte.
PubMed: The effect of the perfluorocarbon emulsion Oxycyte on platelet count and function in the treatment of decompression sickness in a swine model.
PubMed: Blood monitoring of perfluorocarbon compounds (F-tert-butylcyclohexane, perfluoromethyldecalin and perfluorodecalin) by headspace-gas chromatography-tandem mass spectrometry.
PubMed: Administration of a second generation perfluorochemical in combination with hyperbaric oxygenation does not provide additional benefit in a model of permanent middle cerebral artery occlusion in rats.
PubMed: Cardiovascular parameters in a mixed-sex swine study of severe decompression sickness treated with the emulsified perfluorocarbon Oxycyte.
PubMed: Recent advances in the pharmacologic treatment of spinal cord injury.
PubMed: Effects of perfluorocarbon emulsions on microvascular blood flow and oxygen transport in a model of severe arterial gas embolism.
PubMed: Pefluorocarbon inhibition of bubble induced Ca2+ transients in an in vitro model of vascular gas embolism.
PubMed: The intravenous perfluorocarbon emulsion Oxycyte does not increase hyperbaric oxygen-related seizures in a non-sedated swine model.
PubMed: Neuroprotective effects of perflurocarbon (oxycyte) after contusive spinal cord injury.
PubMed: Perfluorocarbon emulsion improves oxygen transport of normal and sickle cell human blood in vitro.
PubMed: Surfactant reduction of cerebral infarct size and behavioral deficit in a rat model of cerebrovascular arterial gas embolism.
PubMed: Use of perfluorocarbons to enhance the performance of perfused three-dimensional hepatic cultures.
PubMed: The emulsified perfluorocarbon Oxycyte improves spinal cord injury in a swine model of decompression sickness.
PubMed: Brain oxygenation and CNS oxygen toxicity after infusion of perfluorocarbon emulsion.
PubMed: Treatment with endotracheal therapeutics after sarin microinstillation inhalation exposure increases blood cholinesterase levels in guinea pigs.
PubMed: Mechanotransductional basis of endothelial cell response to intravascular bubbles.
PubMed: Use of a third-generation perfluorocarbon for preservation of rat DCD liver grafts.
PubMed: Delaying blood transfusion in experimental acute anemia with a perfluorocarbon emulsion.
PubMed: Perfluorocarbon emulsions improve cognitive recovery after lateral fluid percussion brain injury in rats.
PubMed: The effect of isovolemic hemodilution with oxycyte, a perfluorocarbon emulsion, on cerebral blood flow in rats.
PubMed: Perfluorocarbon administration during cardiopulmonary bypass in rats: an inflammatory link to adverse outcome?
PubMed: A new method for superselective middle cerebral artery infusion in the rat.
PubMed: Early administration of a second-generation perfluorochemical decreases ischemic brain damage in a model of permanent middle cerebral artery occlusion in the rat.
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