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1,4-anthraquinone
1,4-anthracenedione

Supplier Sponsors

Name:anthracene-1,4-dione
CAS Number: 635-12-1Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:211-228-7
FDA UNII: Search
Nikkaji Web:J6.908F
MDL:MFCD00013724
XlogP3:3.00 (est)
Molecular Weight:208.21616000
Formula:C14 H8 O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 406.00 °C. @ 760.00 mm Hg (est)
Flash Point: 306.00 °F. TCC ( 152.00 °C. ) (est)
logP (o/w): 3.020 (est)
Soluble in:
 water, 150 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
ExtraSynthese
For experimental / research use only.
1,4-Anthraquinone (HPLC) ≥90%
Santa Cruz Biotechnology
For experimental / research use only.
1,4-Anthraquinone
Sigma-Aldrich: Aldrich
For experimental / research use only.
Anthracene-1,4-dione
TCI AMERICA
For experimental / research use only.
1,4-Anthraquinone >95.0%(GC)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for 1,4-anthraquinone usage levels up to:
 not for fragrance use.
 
Recommendation for 1,4-anthraquinone flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :69457
National Institute of Allergy and Infectious Diseases:Data
anthracene-1,4-dione
Chemidplus:0000635121
 
References:
 anthracene-1,4-dione
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):69457
Pubchem (sid):135026140
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 found in nature
 
Synonyms:
 anthracene-1,4-dione
1,4-anthracenedione
1,4-dioxoanthracene
 

Articles:

PubMed:Reactive paper spray mass spectrometry for in situ identification of quinones.
PubMed:Proton translocation in monomolecular Langmuir-Blodgett films including 2-naphthol and 1,4-anthraquinone derivatives.
PubMed:Excited-state dynamical behavior of 1,4-anthraquinone in a fluid solution.
PubMed:1,4-Anthraquinone: an anticancer drug that blocks nucleoside transport, inhibits macromolecule synthesis, induces DNA fragmentation, and decreases the growth and viability of L1210 leukemic cells in the same nanomolar range as daunorubicin in vitro.
PubMed:Ex(2)Box: interdependent modes of binding in a two-nanometer-long synthetic receptor.
PubMed:Synthesis of a small library of 2-phenoxy-1,4-naphthoquinone and 2-phenoxy-1,4-anthraquinone derivatives bearing anti-trypanosomal and anti-leishmanial activity.
PubMed:[Partially hydrogenated aryl-1,2/1,4-anthraquinone derivatives, 5-lipoxygenase inhibitors with arotinoid structure].
PubMed:Solvatochromism, preferential solvation of 2,3-bis(chloromethyl)-1,4-anthraquinone in binary mixtures and the molecular recognition towards p-tert-butyl-calix[4]arene.
PubMed:Self-assembled hexanuclear organometallic cages: synthesis, characterization, and host-guest properties.
PubMed:Spectral investigations on 2,3-bis(chloromethyl)-1,4- anthraquinone: solvent effects and host-guest interactions.
PubMed:Polyanthraquinone as a Reliable Organic Electrode for Stable and Fast Lithium Storage.
PubMed:2-Phenoxy-1,4-naphthoquinones: From a Multitarget Antitrypanosomal to a Potential Antitumor Profile.
PubMed:6,7-Dimeth-oxy-1,4-anthraquinone.
PubMed:Chemoenzymatic synthesis of novel C-ribosylated naphthoquinones.
PubMed:Role of LHCII organization in the interaction of substituted 1,4-anthraquinones with thylakoid membranes.
PubMed:Concise total syntheses of variecolortides A and B through an unusual hetero-Diels-Alder reaction.
PubMed:Lateral extension of π conjugation along the bay regions of bisanthene through a Diels-Alder cycloaddition reaction.
PubMed:A new approach to evaluating the extent of Michael adduct formation to PAH quinones: tetramethylammonium hydroxide (TMAH) thermochemolysis with GC/MS.
PubMed:Novel substituted 1,4-anthracenediones with antitumor activity directly induce permeability transition in isolated mitochondria.
PubMed:Rapid collapse of mitochondrial transmembrane potential in HL-60 cells and isolated mitochondria treated with anti-tumor 1,4-anthracenediones.
PubMed:Influence of substituted 1,4-anthraquinones on the chlorophyll fluorescence and photochemical activity of pea thylakoid membranes.
PubMed:Electronic structure of the lowest excited triplet state of 5,12-naphthacenequinone.
PubMed:Anthraquinones from hedyotis herbacea
PubMed:Synthetic 1,4-anthracenedione analogs induce cytochrome c release, caspase-9, -3, and -8 activities, poly(ADP-ribose) polymerase-1 cleavage and internucleosomal DNA fragmentation in HL-60 cells by a mechanism which involves caspase-2 activation but not Fas signaling.
PubMed:Synthetic 1,4-anthracenediones, which block nucleoside transport and induce DNA fragmentation, retain their cytotoxic efficacy in daunorubicin-resistant HL-60 cell lines.
PubMed:Synthesis of indan-based unusual alpha-amino acid derivatives under phase-transfer catalysis conditions.
PubMed:Alpha-glucosidase inhibitory anthranols, kenganthranols A-C, from the stem bark of Harungana madagascariensis.
PubMed:1,4,9,10-Anthradiquinone as precursor for antitumor compounds.
PubMed:The thermodynamic properties of some commonly used oxidation-reduction mediators, inhibitors and dyes, as determined by polarography.
PubMed:Digitally enhanced thin layer chromatography: further development and some applications in isotopic chemistry.
 
Notes:
None found
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