EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

alpha-boswellic acid
olean-12-en-24-oic acid, 3-hydroxy-, (3a)-

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Name:(3R,4R,4aR,6aR,6bS,8aR,12aR,14aR,14bR)-3-hydroxy-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicene-4-carboxylic acid
CAS Number: 471-66-9Picture of molecule3D/inchi
FDA UNII: Search
Nikkaji Web:J12.038C
Beilstein Number:3074442
MDL:MFCD03788779
XlogP3-AA:8.40 (est)
Molecular Weight:456.71016000
Formula:C30 H48 O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 552.70 °C. @ 760.00 mm Hg (est)
Flash Point: 576.00 °F. TCC ( 302.10 °C. ) (est)
logP (o/w): 9.430 (est)
Soluble in:
 water, 0.001748 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
None found
 
Suppliers:
Alfa Biotechnology
For experimental / research use only.
Alpha-Boswellic acid 98%
BOC Sciences
For experimental / research use only.
alpha-Boswellic acid 98%
Odor: characteristic
Use: a-Boswellic acid isolated from the herbs of Boswellia carterii Birdw.
ExtraSynthese
For experimental / research use only.
alpha-Boswellic Acid (HPLC) ≥90%
Santa Cruz Biotechnology
For experimental / research use only.
a-Boswellic Acid ≥95%
Sigma-Aldrich
For experimental / research use only.
a-Boswellic Acid analytical standard
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
natural substances and extractives
Recommendation for alpha-boswellic acid usage levels up to:
 not for fragrance use.
 
Recommendation for alpha-boswellic acid flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :637234
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
(3R,4R,4aR,6aR,6bS,8aR,12aR,14aR,14bR)-3-hydroxy-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicene-4-carboxylic acid
 
References:
 (3R,4R,4aR,6aR,6bS,8aR,12aR,14aR,14bR)-3-hydroxy-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicene-4-carboxylic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):637234
Pubchem (sid):43759577
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
HMDB (The Human Metabolome Database):Search
VCF-Online:VCF Volatile Compounds in Food
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 found in nature
 
Synonyms:
a-boswellic acid
(3R,4R,4aR,6aR,6bS,8aR,12aR,14aR,14bR)-3-hydroxy-4,6a,6b,8a,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicene-4-carboxylic acid
(3a)-3-hydroxyolean-12-en-24-oic acid
 olean-12-en-24-oic acid, 3-hydroxy-, (3a)-
 

Articles:

PubMed:[Change in dissolution of chemical components of frankincense-myrrh before and after their compatibility and effect on no release of LPS-induced macrophage cells].
PubMed:In vitro metabolism, permeation, and brain availability of six major boswellic acids from Boswellia serrata gum resins.
PubMed:Enhanced absorption of boswellic acids by a lecithin delivery form (Phytosome(®)) of Boswellia extract.
PubMed:[Determination of five boswellic acids in Boswellia serrata].
PubMed:Antituberculosis cycloartane triterpenoids from Radermachera boniana.
PubMed:Two new triterpenoids from the resin of Boswellia carterii.
PubMed:Discovery of cyclooxygenase inhibitors from medicinal plants used to treat inflammation.
PubMed:A norsesquiterpene lactone and a benzoic acid derivative from the leaves of Cyclocarya paliurus and their glucosidase and glycogen phosphorylase inhibiting activities.
PubMed:Characterization of 3alpha-acetyl-11-keto-alpha-boswellic acid, a pentacyclic triterpenoid inducing apoptosis in vitro and in vivo.
PubMed:Analysis of frankincense from various Boswellia species with inhibitory activity on human drug metabolising cytochrome P450 enzymes using liquid chromatography mass spectrometry after automated on-line extraction.
PubMed:High-performance liquid chromatographic determination of acetyl-11-keto-alpha-boswellic acid, a novel pentacyclic triterpenoid, in plasma using a fluorinated stationary phase and photodiode array detection: application in pharmacokinetic studies.
PubMed:Boswellic acid acetate induces apoptosis through caspase-mediated pathways in myeloid leukemia cells.
PubMed:Effect of food intake on the bioavailability of boswellic acids from a herbal preparation in healthy volunteers.
PubMed:Acetyl-boswellic acids inhibit lipopolysaccharide-mediated TNF-alpha induction in monocytes by direct interaction with IkappaB kinases.
PubMed:Characterization of archaeological frankincense by gas chromatography-mass spectrometry.
PubMed:Immunomodulatory triterpenoids from the oleogum resin of Boswellia carterii Birdwood.
PubMed:[Chemical components of Boswellia carterii].
PubMed:A lupane triterpene from frankincense (Boswellia sp., Burseraceae).
 
Notes:
None found
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