Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
Assay: | 95.00 to 100.00
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Food Chemicals Codex Listed: | No |
Boiling Point: | 722.20 °C. @ 760.00 mm Hg (est)
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Flash Point: | 513.00 °F. TCC ( 267.10 °C. ) (est)
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logP (o/w): | -1.930 (est) |
Soluble in: |
| water, 1.912e+005 mg/L @ 25 °C (est) |
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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Hazards identification |
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Classification of the substance or mixture |
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
None found. |
GHS Label elements, including precautionary statements |
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Pictogram | |
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Hazard statement(s) |
None found. |
Precautionary statement(s) |
None found. |
Oral/Parenteral Toxicity: |
Not determined
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Dermal Toxicity: |
Not determined
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Inhalation Toxicity: |
Not determined
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Safety in Use Information:
Category: | natural substances and extractives |
Recommendation for fraxin usage levels up to: | | not for fragrance use.
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Recommendation for fraxin flavor usage levels up to: |
| not for flavor use.
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Safety References:
References:
| 7-hydroxy-6-methoxy-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one |
NIST Chemistry WebBook: | Search Inchi |
Pubchem (cid): | 5273568 |
Pubchem (sid): | 135227410 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
2H-1- | benzopyran-2-one, 8-(beta-D-glucopyranosyloxy)-7-hydroxy-6-methoxy- | | fraxetin-8-O-glucoside | 8-(beta-D- | glucopyranosyloxy)-7-hydroxy-6-methoxy-2h-1-benzopyran-2-one | 7- | hydroxy-6-methoxy-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-2-one | | paviin |
Articles:
PubMed:Simultaneous Determination of Five Constituents in Qinpijiegu Capsule by High-Performance Liquid Chromatography Coupled with Tandem Mass Spectrometry. |
PubMed:Purification of Coumarin Compounds From Cortex fraxinus by Adsorption Chromatography. |
PubMed:[Quantitative method for simultaneous assay of four coumarins with one marker in Fraxini Cortex]. |
PubMed:Antioxidative and anti-inflammatory effects of phenolic compounds from the roots of Ulmus macrocarpa. |
PubMed:Screening for novel quorum-sensing inhibitors to interfere with the formation of Pseudomonas aeruginosa biofilm. |
PubMed:Protective effects of cortex fraxini coumarines against oxonate-induced hyperuricemia and renal dysfunction in mice. |
PubMed:Inhibitory effects of coumarins from the stem barks of Fraxinus rhynchophylla on adipocyte differentiation in 3T3-L1 cells. |
PubMed:A new phenolic compound, 4-dehydrochebulic acid-1,6-dimethyl ester from Sapium insigne leaves. |
PubMed:[Studies on chemical constituents from stem barks of Fraxinus paxiana]. |
PubMed:[Coumarins from branch of Fraxinus sieboldiana and their antioxidative activity]. |
PubMed:Functional analysis of LjSUT4, a vacuolar sucrose transporter from Lotus japonicus. |
PubMed:Simultaneous analysis of coumarins and secoiridoids in Cortex Fraxini by high-performance liquid chromatography-diode array detection-electrospray ionization tandem mass spectrometry. |
PubMed:Cytotoxic phenolic constituents of Acer tegmentosum maxim. |
PubMed:Arabidopsis sucrose transporter AtSUC9. High-affinity transport activity, intragenic control of expression, and early flowering mutant phenotype. |
PubMed:Metabolic fate of fraxin administered orally to rats. |
PubMed:Solution to spectroscopy challenge 10. |
PubMed:Natural compounds,fraxin and chemicals structurally related to fraxin protect cells from oxidative stress. |
PubMed:A new compound from Rhododendren anthopogonosides maxim. |
PubMed:Analysis and bioactive evaluation of the compounds absorbed into blood after oral administration of the extracts of Vaccinium vitis-idaea in rat. |
PubMed:Isolation and purification of coumarin compounds from Cortex fraxinus by high-speed counter-current chromatography. |
PubMed:Non-aqueous capillary electrophoresis for separation and simultaneous determination of fraxin, esculin and esculetin in Cortex fraxini and its medicinal preparations. |
PubMed:HIV gp41 binding phenolic components from Fraxinus sieboldiana var. angustata. |
PubMed:Effect of organic cosolvents on the stability and activity of the beta-1,4-galactosyltransferase from bovine colostrum. |
PubMed:Structure-activity relationship of coumarins in xanthine oxidase inhibition. |
PubMed:Effect of some hydroxycoumarins on complement-mediated hemolysis in human serum. |
PubMed:Reversed-phase HPTLC densitometric evaluation of fraxin in Fraxinus excelsior leaves. |
PubMed:Role of sulfate concentration in dechlorination of 3,4,5-trichlorocatechol by stable enrichment cultures grown with coumarin and flavanone glycones and aglycones. |
PubMed:Semisynthetic transformations of fraxin to biological active compounds. |
PubMed:Fast atom bombardment and tandem mass spectrometry for structure determination of steroid and flavonoid glycosides. |
PubMed:Inhibition of the formation of 5-hydroxy-6,8,11,14-eicosatetraenoic acid from arachidonic acid in polymorphonuclear leukocytes by various coumarins. |
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