| PubMed:Core Bioactive Components Promoting Blood Circulation in the Traditional Chinese Medicine Compound Xueshuantong Capsule (CXC) Based on the Relevance Analysis between Chemical HPLC Fingerprint and In Vivo Biological Effects. |
| PubMed:Effect of a soluble prebiotic fiber, NUTRIOSE, on the absorption of ginsenoside Rd in rats orally administered ginseng. |
| PubMed:Ginsenoside Rd inhibits apoptosis following spinal cord ischemia/reperfusion injury. |
| PubMed:The Bioconversion of Red Ginseng Ethanol Extract into Compound K by Saccharomyces cerevisiae HJ-014. |
| PubMed:[Determination of twelve active compounds in Qili Qiangxin capsules by UPLC-MS]. |
| PubMed:Relative quantification of multi-components in Panax notoginseng (Sanqi) by high-performance liquid chromatography with mass spectrometry using mobile phase compensation. |
| PubMed:A comparative study of using in-line near-infrared spectra, ultraviolet spectra and fused spectra to monitor Panax notoginseng adsorption process. |
| PubMed:[Effect of light quality on growth, photosynthesis and effective components of Panax notoginseng]. |
| PubMed:[Fermentation transformed ginsenoside by Lactobacillus plantarum]. |
| PubMed:Ginsenoside Rd attenuates mitochondrial permeability transition and cytochrome C release in isolated spinal cord mitochondria: involvement of kinase-mediated pathways. |
| PubMed:Characterization of recombinant β-glucosidase from Arthrobacter chlorophenolicus and biotransformation of ginsenosides Rb1, Rb 2, Rc, and Rd. |
| PubMed:Ginsenoside Rd ameliorates experimental autoimmune encephalomyelitis in C57BL/6 mice. |
| PubMed:Ginsenoside Rd attenuates tau protein phosphorylation via the PI3K/AKT/GSK-3β pathway after transient forebrain ischemia. |
| PubMed:[Major hypoglycemic ingredients of panax notoginseng saponins for treating diabetes]. |
| PubMed:Simultaneous quantitation of polygalaxanthone III and four ginsenosides by ultra-fast liquid chromatography with tandem mass spectrometry in rat and beagle dog plasma after oral administration of Kai-Xin-San: application to a comparative pharmacokinetic study. |
| PubMed:[Chemical constituents from processed rhizomes of Panax notoginseng]. |
| PubMed:Evaluation of glucosidases of Aspergillus niger strain comparing with other glucosidases in transformation of ginsenoside Rb1 to ginsenosides Rg3. |
| PubMed:Efficacy comparison of Korean ginseng and American ginseng on body temperature and metabolic parameters. |
| PubMed:Ginsenoside-Rd exhibits anti-inflammatory activities through elevation of antioxidant enzyme activities and inhibition of JNK and ERK activation in vivo. |
| PubMed:[Chemical constituents from roots and rhizomes of Panax ginseng cultivated in Jilin province]. |
| PubMed:Ginsenoside Rd promotes glutamate clearance by up-regulating glial glutamate transporter GLT-1 via PI3K/AKT and ERK1/2 pathways. |
| PubMed:Progress on the protective effect of compounds from natural medicines on cerebral ischemia. |
| PubMed:Biotransformation of ginsenoside Rb1 via the gypenoside pathway by human gut bacteria. |
| PubMed:Ginsenoside Rb1 is transformed into Rd and Rh2 by Microbacterium trichothecenolyticum. |
| PubMed:Ginsenoside Rd induces protective anti-Candida albicans antibody through immunological adjuvant activity. |
| PubMed:Biotransformation of ginsenoside Rd in the ginseng extraction residue by fermentation with lingzhi (Ganoderma lucidum). |
| PubMed:Efficient thermal deglycosylation of ginsenoside Rd and its contribution to the improved anticancer activity of ginseng. |
| PubMed:Ginsenoside Rd attenuates myocardial ischemia/reperfusion injury via Akt/GSK-3β signaling and inhibition of the mitochondria-dependent apoptotic pathway. |
| PubMed:A UFLC-MS/MS method with a switching ionization mode for simultaneous quantitation of polygalaxanthone III, four ginsenosides and tumulosic acid in rat plasma: application to a comparative pharmacokinetic study in normal and Alzheimer's disease rats. |
| PubMed:The anaphylactoid constituents in Xue-Sai-Tong injection. |
| PubMed:Ginsenoside Rd for acute ischemic stroke: translating from bench to bedside. |
| PubMed:Involvement of melastatin type transient receptor potential 7 channels in ginsenoside Rd-induced apoptosis in gastric and breast cancer cells. |
| PubMed:Ginsenoside Rd inhibits the expressions of iNOS and COX-2 by suppressing NF-κB in LPS-stimulated RAW264.7 cells and mouse liver. |
| PubMed:Inhibition of TNF-α-mediated NF-κB Transcriptional Activity in HepG2 Cells by Dammarane-type Saponins from Panax ginseng Leaves. |
| PubMed:Isolation and characterization of novel ginsenoside-hydrolyzing glycosidase from Microbacterium esteraromaticum that transforms ginsenoside Rb2 to rare ginsenoside 20(S)-Rg3. |
| PubMed:Simultaneous determination of three alkaloids, four ginsenosides and limonin in the plasma of normal and headache rats after oral administration of Wu-Zhu-Yu decoction by a novel ultra fast liquid chromatography-tandem mass spectrometry method: application to a comparative pharmacokinetics and ethological study. |
| PubMed:Production of ginsenoside Rd from ginsenoside Rc by α-L-arabinofuranosidase from Caldicellulosiruptor saccharolyticus. |
| PubMed:Novosphingobium ginsenosidimutans sp. nov., with the ability to convert ginsenoside. |
| PubMed:Compound K, a final intestinal metabolite of ginsenosides, enhances insulin secretion in MIN6 pancreatic β-cells by upregulation of GLUT2. |
| PubMed:Enhancement of ginsenoside biosynthesis in cell cultures of Panax ginseng by N,N'-dicyclohexylcarbodiimide elicitation. |
| PubMed:Ginsenoside Rd blocks AIF mitochondrio-nuclear translocation and NF-κB nuclear accumulation by inhibiting poly(ADP-ribose) polymerase-1 after focal cerebral ischemia in rats. |
| PubMed:Studies on the interactions between ginsenosides and liposome by equilibrium dialysis combined with ultrahigh performance liquid chromatography-tandem mass spectrometry. |
| PubMed:Wound-healing effect of ginsenoside Rd from leaves of Panax ginseng via cyclic AMP-dependent protein kinase pathway. |
| PubMed:Microbial transformation of ginsenoside Rb1 to compound K by Lactobacillus paralimentarius. |
| PubMed:Ginsenoside Rd attenuates beta-amyloid-induced tau phosphorylation by altering the functional balance of glycogen synthase kinase 3beta and protein phosphatase 2A. |
| PubMed:Saponins composition of rhizomes, taproots, and lateral roots of Satsuma-ninjin (Panax japonicus). |
| PubMed:Lactobacillus ginsenosidimutans sp. nov., isolated from kimchi with the ability to transform ginsenosides. |
| PubMed:Four new triterpenoid saponins from the leaves of Panax japonicus grown in southern Miyazaki Prefecture (4). |
| PubMed:Bioconversion of ginsenoside Rc into Rd by a novel α-L-arabinofuranosidase, Abf22-3 from Leuconostoc sp. 22-3: cloning, expression, and enzyme characterization. |
| PubMed:Purification and Characterization of a Ginsenoside Rb(1)-Hydrolyzing β-Glucosidase from Aspergillus niger KCCM 11239. |
| PubMed:Ginsenoside Rd maintains adult neural stem cell proliferation during lead-impaired neurogenesis. |
| PubMed:Ginsenosides Rb₁ and Rd regulate proliferation of mature keratinocytes through induction of p63 expression in hair follicles. |
| PubMed:Ginsennoside rd attenuates cognitive dysfunction in a rat model of Alzheimer's disease. |
| PubMed:Therapeutic effect of ginsenoside Rd in rats with TNBS-induced recurrent ulcerative colitis. |
| PubMed:Effects of external calcium on the biotransformation of ginsenoside Rb1 to ginsenoside Rd by Paecilomyces bainier 229-7. |
| PubMed:Highly selective microbial transformation of major ginsenoside Rb1 to gypenoside LXXV by Esteya vermicola CNU120806. |
| PubMed:Promotive effect of ginsenoside Rd on proliferation of neural stem cells in vivo and in vitro. |
| PubMed:Production of rare ginsenosides (compound Mc, compound Y and aglycon protopanaxadiol) by β-glucosidase from Dictyoglomus turgidum that hydrolyzes β-linked, but not α-linked, sugars in ginsenosides. |
| PubMed:Metabolism of ginsenoside Rb1 by human intestinal microflora and cloning of its metabolizing β-D-glucosidase from Bifidobacterium longum H-1. |
| PubMed:Enzymatic biotransformation of ginsenoside Rb1 to compound K by recombinant β-glucosidase from Microbacterium esteraromaticum. |
| PubMed:[Identification of major components of traditional Chinese medicine Naodesheng tablet by HPLC-DAD-MS(n)]. |
| PubMed:Inhibitory effect of ginsenoside-Rd on carrageenan-induced inflammation in rats. |
| PubMed:Is there a future for neuroprotective agents in acute ischaemic stroke? |
| PubMed:Ginsenoside-Rd improves outcome of acute ischaemic stroke - a randomized, double-blind, placebo-controlled, multicenter trial. |
| PubMed:Ginsenoside-Rd attenuates TRPM7 and ASIC1a but promotes ASIC2a expression in rats after focal cerebral ischemia. |
| PubMed:Ginsenoside Rd attenuates the inflammatory response via modulating p38 and JNK signaling pathways in rats with TNBS-induced relapsing colitis. |
| PubMed:Characterization of a novel ginsenoside-hydrolyzing α-L-arabinofuranosidase, AbfA, from Rhodanobacter ginsenosidimutans Gsoil 3054T. |
| PubMed:Ginsenoside-Rd potentiates apoptosis induced by hydrogen peroxide in basilar artery smooth muscle cells through the mitochondrial pathway. |
| PubMed:Ginsenoside Rd stimulates the differentiation and mineralization of osteoblastic MC3T3-E1 cells by activating AMP-activated protein kinase via the BMP-2 signaling pathway. |
| PubMed:[Screening of plant pathogenic fungi by ginsenoside compound K production]. |
| PubMed:Anti-metastatic effects of ginsenoside Rd via inactivation of MAPK signaling and induction of focal adhesion formation. |
| PubMed:Protective effects of ginsenoside Rd against okadaic acid-induced neurotoxicity in vivo and in vitro. |
| PubMed:Pharmacokinetic, tissue distribution and excretion of ginsenoside-Rd in rodents. |
| PubMed:Biotransformation of Ginsenoside Rb1 to Prosapogenins, Gypenoside XVII, Ginsenoside Rd, Ginsenoside F2, and Compound K by Leuconostoc mesenteroides DC102. |
| PubMed:Immunosuppressive effects of ginsenoside-Rd on skin allograft rejection in rats. |
| PubMed:Ginsenoside Rd protects neurons against glutamate-induced excitotoxicity by inhibiting ca(2+) influx. |
| PubMed:Bioconversion of ginsenoside rb1 into compound k by Leuconostoc citreum LH1 isolated from kimchi. |
| PubMed:Ginsenoside Rd attenuates redox imbalance and improves stroke outcome after focal cerebral ischemia in aged mice. |
| PubMed:Ginsenoside rd in experimental stroke: superior neuroprotective efficacy with a wide therapeutic window. |
| PubMed:Ginsenoside Rd attenuates mitochondrial dysfunction and sequential apoptosis after transient focal ischemia. |
| PubMed:Ginsenoside Rd attenuates early oxidative damage and sequential inflammatory response after transient focal ischemia in rats. |
| PubMed:Ginsenoside-Rd, a purified component from panax notoginseng saponins, prevents atherosclerosis in apoE knockout mice. |
| PubMed:Production of aglycon protopanaxadiol via compound K by a thermostable β-glycosidase from Pyrococcus furiosus. |
| PubMed:Preparative chromatography of flavonoids and saponins in Gynostemma pentaphyllum and their antiproliferation effect on hepatoma cell. |
| PubMed:Biotransformation of ginsenoside Rb1 to ginsenoside Rd by highly substrate-tolerant Paecilomyces bainier 229-7. |
| PubMed:Increased ubiquitination of multidrug resistance 1 by ginsenoside Rd. |
| PubMed:Pharmacokinetics and safety of ginsenoside Rd following a single or multiple intravenous dose in healthy Chinese volunteers. |
| PubMed:Absorption and disposition of ginsenosides after oral administration of Panax notoginseng extract to rats. |
| PubMed:Dammarane-type glycosides and long chain sesquiterpene glycosides from Gynostemma yixingense. |
| PubMed:Ginsenoside Rd prevents glutamate-induced apoptosis in rat cortical neurons. |
| PubMed:Differential effect of Shenmai injection, a herbal preparation, on the cytochrome P450 3A-mediated 1'-hydroxylation and 4-hydroxylation of midazolam. |
| PubMed:Panax ginseng C.A. Meyer modulates the levels of MMP3 in S12 murine articular cartilage cell line. |
| PubMed:Neuroprotective effects of ginsenoside Rd against oxygen-glucose deprivation in cultured hippocampal neurons. |
| PubMed:Proteome changes related to the anti-cancer activity of HT29 cells by the treatment of ginsenoside Rd. |
| PubMed:Ginsenoside-Rd, a new voltage-independent Ca2+ entry blocker, reverses basilar hypertrophic remodeling in stroke-prone renovascular hypertensive rats. |
| PubMed:[A quantitative method using one marker for simultaneous assay of ginsenosides in Panax ginseng and P. notoginseng]. |
| PubMed:Effects of extrusion process variables on extractable ginsenosides in wheat-ginseng extrudates. |
| PubMed:Efficacy and safety of ginsenoside-Rd for acute ischaemic stroke: a randomized, double-blind, placebo-controlled, phase II multicenter trial. |
| PubMed:Highly selective biotransformation of ginsenoside Rb1 to Rd by the phytopathogenic fungus Cladosporium fulvum (syn. Fulvia fulva). |
| PubMed:Ginsenoside compound K production from ginseng root extract by a thermostable beta-glycosidase from Sulfolobus solfataricus. |
| PubMed:Role of ginsenoside Rd in inhibiting 26S proteasome activity. |
| PubMed:Simultaneous determination of nucleobases, nucleosides and saponins in Panax notoginseng using multiple columns high performance liquid chromatography. |
| PubMed:Pressure and electrokinetic injections for on-line sample stacking neutral analytes in microemulsion electrokinetic chromatography with salt-containing matrixes. |
| PubMed:Protective effects of ginsenoside Rd on PC12 cells against hydrogen peroxide. |
| PubMed:[Purification and characterization of a beta-D-xylosidase from Leifsonia shinshuensis DICP 16]. |
| PubMed:Ginsenoside Rd prevents and rescues rat intestinal epithelial cells from irradiation-induced apoptosis. |
| PubMed:Comparative analysis on microbial and rat metabolism of ginsenoside Rb1 by high-performance liquid chromatography coupled with tandem mass spectrometry. |
| PubMed:[Studies on chemical constituents from rhizomes of Panax notoginseng]. |
| PubMed:Purification method improvement and characterization of a novel ginsenoside-hydrolyzing beta-glucosidase from Paecilomyces Bainier sp. 229. |
| PubMed:Role of jasmonic acid in alteration of ginsenoside heterogeneity in elicited cell cultures of Panax notoginseng. |
| PubMed:Ginsenoside Rd enhances glutathione levels in H4IIE cells via NF-kappaB-dependent gamma-glutamylcysteine ligase induction. |
| PubMed:Screening and characterization of an enzyme with beta-glucosidase activity from environmental DNA. |
| PubMed:Microbial transformation of ginsenoside Rb(1) by Acremonium strictum. |
| PubMed:Ginsenoside Rd production from the major ginsenoside Rb(1) by beta-glucosidase from Thermus caldophilus. |
| PubMed:Ginsenoside Rd attenuates neuroinflammation of dopaminergic cells in culture. |
| PubMed:Marked production of ginsenosides Rd, F2, Rg3, and compound K by enzymatic method. |
| PubMed:Medicinal flowers. XVI. New dammarane-type triterpene tetraglycosides and gastroprotective principles from flower buds of Panax ginseng. |
| PubMed:In vivo pharmacokinetic and metabolism studies of ginsenoside Rd. |
| PubMed:Induction of cyclooxygenase-2 by ginsenoside Rd via activation of CCAAT-enhancer binding proteins and cyclic AMP response binding protein. |
| PubMed:Differential effects of ginsenosides on NO and TNF-alpha production by LPS-activated N9 microglia. |
| PubMed:Determination of ginsenoside Rd in dog plasma by liquid chromatography-mass spectrometry after solid-phase extraction and its application in dog pharmacokinetics studies. |
| PubMed:[Determination of ginsenoside rd in human plasma by LC/MS/MS]. |
| PubMed:Ginsenoside Rd from Panax notoginseng is cytotoxic towards HeLa cancer cells and induces apoptosis. |
| PubMed:[Determination of ginsenoside Rd and its metabolites in rat urine by LC-MS]. |
| PubMed:Ginsenoside-Rd from panax notoginseng blocks Ca2+ influx through receptor- and store-operated Ca2+ channels in vascular smooth muscle cells. |
| PubMed:Ginsenoside Rd elicits Th1 and Th2 immune responses to ovalbumin in mice. |
| PubMed:In vitro anti-cancer activity and structure-activity relationships of natural products isolated from fruits of Panax ginseng. |
| PubMed:Effects of individual ginsenosides, ginkgolides and flavonoids on CYP2C19 and CYP2D6 activity in human liver microsomes. |
| PubMed:Conversion of major ginsenoside Rb1 to ginsenoside F2 by Caulobacter leidyia. |
| PubMed:[Purification of a ginsenoside-Rb1 hydrolase from Helix snailase]. |
| PubMed:Induction and characterization of adventitious roots directly from the explants of Panax notoginseng. |
| PubMed:The growth characteristics and ginsenosides isolation of suspension-cultured crown gall of Panax quinquefolium. |
| PubMed:Microbial conversion of major ginsenoside rb(1) to pharmaceutically active minor ginsenoside rd. |
| PubMed:Manipulation of ginsenoside heterogeneity in cell cultures of Panax notoginseng by addition of jasmonates. |
| PubMed:Orthogonal array design in optimizing the extraction efficiency of active constituents from roots of Panax notoginseng. |
| PubMed:High-performance liquid chromatographic assay for the active saponins from Panax notoginseng in rat tissues. |
| PubMed:Bronchodilatory effects of the aqueous extract of Gynostemma pentaphyllum and gypenosides III and VIII in anaesthetized guinea-pigs. |
| PubMed:Efficient induction of ginsenoside biosynthesis and alteration of ginsenoside heterogeneity in cell cultures of Panax notoginseng by using chemically synthesized 2-hydroxyethyl jasmonate. |
| PubMed:Chromatographic resolution of glucosidic compounds, ginsenosides on polyethersulphone membrane, and its application to the quantitative immunoassay for ginseng saponins. |
| PubMed:Enhancement of ginsenoside biosynthesis in high-density cultivation of Panax notoginseng cells by various strategies of methyl jasmonate elicitation. |
| PubMed:Impact of external calcium and calcium sensors on ginsenoside Rb1 biosynthesis by Panax notoginseng cells. |
| PubMed:Ginsenoside-Rd from Panax notoginseng enhances astrocyte differentiation from neural stem cells. |
| PubMed:HPLC determination of four active saponins from Panax notoginseng in rat serum and its application to pharmacokinetic studies. |
| PubMed:Dammarane-type glycosides from Gynostemma pentaphyllum. |
| PubMed:The inhibitory effects of herbal components on CYP2C9 and CYP3A4 catalytic activities in human liver microsomes. |
| PubMed:Ginsenoside-Rd attenuates oxidative damage related to aging in senescence-accelerated mice. |
| PubMed:Effect of ginsenoside Rd on nitric oxide system induced by lipopolysaccharide plus TNF-alpha in C6 rat glioma cells. |
| PubMed:Effects of ginsenoside Rd and decursinol on the neurotoxic responses induced by kainic acid in mice. |
| PubMed:[Metabolism of ginsenoside Rb1 and panaxadiol saponins by fungi]. |
| PubMed:[Determination of six ginsenosides in Panax species by high performance liquid chromatography]. |
| PubMed:Components of Panax ginseng that improve accelerated small intestinal transit. |
| PubMed:Role of ginsenoside-Rd in cisplatin-induced renal injury: special reference to DNA fragmentation. |
| PubMed:Effects of ginsenosides from Panax ginseng on cell-to-cell communication function mediated by gap junctions. |
| PubMed:Constitutive beta-glucosidases hydrolyzing ginsenoside Rb1 and Rb2 from human intestinal bacteria. |
| PubMed:Somatic embryogenesis and ginsenoside production of Panax ginseng in phytohormone-free medium. |
| PubMed:The role of ginsenoside-Rd in cisplatin-induced acute renal failure. |
| PubMed:Screening of anti-hypoxia/reoxygenation agents by an in vitro method. Part 2: Inhibition of tyrosine kinase activation prevented hypoxia/reoxygenation-induced injury in endothelial gap junctional intercellular communication. |
| PubMed:Screening of anti-hypoxia/reoxygenation agents by an in vitro model. Part 1: Natural inhibitors for protein tyrosine kinase activated by hypoxia/reoxygenation in cultured human umbilical vein endothelial cells. |
| PubMed:Effects of ginseng components on c-DNA-expressed cytochrome P450 enzyme catalytic activity. |
| PubMed:Formation of monoclonal antibody against a major ginseng component, ginsenoside Rb1 and its characterization. |
| PubMed:Effect of ginsenoside-Rd in cephaloridine-induced renal disorder. |
| PubMed:Intestinal bacterial hydrolysis is required for the appearance of compound K in rat plasma after oral administration of ginsenoside Rb1 from Panax ginseng. |
| PubMed:A study of ginsenoside-Rd in a renal ischemia-reperfusion model. |
| PubMed:Ginsenosides increase secretion of lipoprotein lipase by 3T3-L1 adipocytes. |
| PubMed:Inhibitory effects of ginseng on proliferation of cultured mouse mesangial cells. |
| PubMed:Studies on absorption, distribution, excretion and metabolism of ginseng saponins. VII. Comparison of the decomposition modes of ginsenoside-Rb1 and -Rb2 in the digestive tract of rats. |
| PubMed:Studies on absorption, distribution, excretion and metabolism of ginseng saponins. V. The decomposition products of ginsenoside Rb2 in the large intestine of rats. |
| PubMed:[Dammarane-type saponins in leaves of Panax collected in Sichuan]. |
| PubMed:Alterations by saponins of passive Ca2+ permeability and Na+-Ca2+ exchange activity of canine cardiac sarcolemmal vesicles. |
| PubMed:Positive inotropic action of saponins on isolated atrial and papillary muscles from the guinea-pig. |
| PubMed:[Rhizoma of ginseng (renshenlutou). 2. Isolation and identification of saponin D1 and D2 from the rhizome of ginseng]. |
| PubMed:Enhancement and suppression in production of IgM-antibody in mice treated with purified saponins. |
| PubMed:Studies on the biochemical action of ginseng saponin. I. Purification from ginseng extract of the active component stimulating serum protein biosynthesis. |
3D/inchi